chr12:110,772,664–110,773,461

chr12 : 110,772,664 – 110,773,461

797 bp 88 TFs 7 linked genes

This 797 bp open chromatin element is linked to 7 target genes and is bound by 88 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PPP1CC		30.1 kb	Distal	Multiome+HiCAR
CCDC63		73.7 kb	Distal	Multiome
HVCN1		83.9 kb	Distal	Multiome
TCTN1		158.9 kb	Distal	Multiome
PPTC7		189.7 kb	Distal	Multiome
CUX2		261.1 kb	Distal	Multiome
VPS29		270.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

88 transcription factors

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 354 bp overlap

ChIP K562 ENCFF938UXQ 255 bp overlap

ARID3A 3 datasets

ChIP GM12878 ENCFF006WWZ 346 bp overlap

ChIP GM12878 ENCSR778UBR.ARID3A.GM12878 194 bp overlap

ChIP Hep-G2 ENCSR000EDP.ARID3A.Hep-G2 125 bp overlap

ChIP GM12878 ENCSR000BQK.ATF2.GM12878 147 bp overlap

ChIP HCT-116_CAMP GSE74355.ATF3.HCT-116_CAMP 140 bp overlap

ATF7 3 datasets

ChIP GM12878 ENCFF037PYH 183 bp overlap

ChIP GM12878 ENCSR014YCR.ATF7.GM12878 371 bp overlap

ChIP K-562 ENCSR972ZBV.ATF7.K-562 356 bp overlap

ChIP CD4_Th1_DMSO GSE62482.BRD4.CD4_Th1_DMSO 111 bp overlap

CBFA2T2 3 datasets

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 345 bp overlap

ChIP K562 ENCFF963TXY 299 bp overlap

ChIP K562 ENCFF963TXY 381 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 467 bp overlap

ChIP K562 ENCFF673OEZ 614 bp overlap

ChIP K562 ENCFF008KGK 219 bp overlap

ChIP K562 ENCFF410AQU 62 bp overlap

ChIP K562 ENCFF188CYP 133 bp overlap

CEBPB 2 datasets

ChIP K-562 ENCSR000EHE.CEBPB.K-562 175 bp overlap

ChIP K562 ENCFF189VBN 271 bp overlap

CEBPD 1 dataset

ChIP K-562 ENCSR000BVY.CEBPD.K-562 205 bp overlap

ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 212 bp overlap

ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 242 bp overlap

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 311 bp overlap

ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 210 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF844FIP 281 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 333 bp overlap

ChIP K562 ENCFF775HUO 493 bp overlap

EP300 2 datasets

ChIP K-562 ENCSR000EGE.EP300.K-562 140 bp overlap

ChIP K562 ENCFF226VMS 317 bp overlap

ESRRA 1 dataset

ChIP SK-BR-3_HRG GSE81651.ESRRA.SK-BR-3_HRG 246 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 797 bp overlap

ChIP DE DE-FOXA2-2 730 bp overlap

FOXJ2 1 dataset

ChIP K562 ENCFF457GZC 512 bp overlap

FOXM1 1 dataset

ChIP K562 ENCFF255RHV 391 bp overlap

GABPB1 1 dataset

ChIP K562 ENCFF015GDS 180 bp overlap

GATA1 5 datasets

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 86 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 264 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 175 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 166 bp overlap

ChIP erythroid-progenitor GSE124163.GATA1.erythroid-progenitor 198 bp overlap

GATA1::TAL1 1 dataset

Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 8 datasets

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 166 bp overlap

ChIP K-562 ENCSR000BKM.GATA2.K-562 144 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 116 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 156 bp overlap

ChIP K562 ENCFF513FTZ 225 bp overlap

ChIP K562 ENCFF513FTZ 301 bp overlap

ChIP K562 ENCFF544PCK 251 bp overlap

ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 130 bp overlap

GATA3 1 dataset

ChIP T-47D ENCSR000BMX.GATA3.T-47D 119 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 797 bp overlap

ChIP DE DE-GATA4-2 753 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 558 bp overlap

GATA6 3 datasets

ChIP DE DE-GATA6-1 739 bp overlap

ChIP DE DE-GATA6-2 736 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 464 bp overlap

Motif DE_72h DE_72h-GFI1_MA0038.3 11 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 162 bp overlap

Gfi1B 1 dataset

Motif DE_72h DE_72h-Gfi1B_MA0483.2 10 bp overlap

HDAC2 2 datasets

ChIP K-562 ENCSR075HTM.HDAC2.K-562 251 bp overlap

ChIP K-562 ENCSR893WSB.HDAC2.K-562 288 bp overlap

ChIP K562 ENCFF783OCM 149 bp overlap

HMG20A 1 dataset

ChIP K562 ENCFF840WDB 588 bp overlap

HOXB13 2 datasets

ChIP prostate-cancer_PDX_167 GSE130408.HOXB13.prostate-cancer_PDX_167 57 bp overlap

ChIP prostate-cancer_PDX_70 GSE130408.HOXB13.prostate-cancer_PDX_70 59 bp overlap

ChIP K-562 ENCSR000FAH.JUN.K-562 118 bp overlap

JUNB 2 datasets

ChIP GM12878 ENCFF667EJQ 324 bp overlap

ChIP GM12878 ENCSR897MMC.JUNB.GM12878 165 bp overlap

KDM1A 5 datasets

ChIP K-562 GSE117944.KDM1A.K-562 51 bp overlap

ChIP K-562 GSE117944.KDM1A.K-562 178 bp overlap

ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 54 bp overlap

ChIP K562 ENCFF128TYE 461 bp overlap

ChIP K562 ENCFF133OLU 461 bp overlap

LDB1 2 datasets

ChIP HEP GSE52637.LDB1.HEP 121 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 296 bp overlap

ChIP HCT-116 ENCSR000BSH.MAX.HCT-116 128 bp overlap

MEF2D 2 datasets

ChIP retina_Hu13 GSE137311.MEF2D.retina_Hu13 279 bp overlap

ChIP retina_Hu25 GSE137311.MEF2D.retina_Hu25 265 bp overlap

MEIS1 1 dataset

Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap

MEIS2 1 dataset

ChIP K-562 ENCSR851BNE.MEIS2.K-562 215 bp overlap

ChIP melanocyte_CTR GSE50681.MITF.melanocyte_CTR 220 bp overlap

NCOR1 3 datasets

ChIP K-562 ENCSR798ILC.NCOR1.K-562 205 bp overlap

ChIP K562 ENCFF788MPU 177 bp overlap

ChIP K562 ENCFF866HRM 212 bp overlap

NEUROD1 5 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 287 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 247 bp overlap

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 188 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 300 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 274 bp overlap

ChIP K562 ENCFF167YID 361 bp overlap

NFXL1 1 dataset

ChIP K562 ENCFF619QDE 147 bp overlap

NR5A2 2 datasets

ChIP A-549 ENCSR190GIW.NR5A2.A-549 277 bp overlap

ChIP A549 ENCFF834RVE 365 bp overlap

ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 357 bp overlap

PKNOX1 1 dataset

ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 226 bp overlap

RAD51 3 datasets

ChIP GM12878 ENCFF916JXQ 357 bp overlap

ChIP GM12878 ENCSR482TWQ.RAD51.GM12878 240 bp overlap

ChIP K-562 ENCSR524BUE.RAD51.K-562 253 bp overlap

RBM25 2 datasets

ChIP K-562 ENCSR791OZM.RBM25.K-562 86 bp overlap

ChIP K562 ENCFF957ORK 86 bp overlap

RFX1 6 datasets

ChIP K-562 ENCSR041AXL.RFX1.K-562 352 bp overlap

ChIP K-562 ENCSR968GIB.RFX1.K-562 275 bp overlap

ChIP K562 ENCFF421AVO 465 bp overlap

ChIP K562 ENCFF809XVG 113 bp overlap

ChIP MCF-7 ENCFF782EZS 441 bp overlap

ChIP MCF-7 ENCSR066TET.RFX1.MCF-7 377 bp overlap

ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 239 bp overlap

SETDB1 4 datasets

ChIP HEK293 ENCFF676PLV 291 bp overlap

ChIP HEK293 ENCFF676PLV 491 bp overlap

ChIP HEK293 ENCSR348AGV.SETDB1.HEK293 218 bp overlap

ChIP U2OS ENCSR000EYD.SETDB1.U2OS 219 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 350 bp overlap

SMARCA4 1 dataset

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 270 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 365 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 257 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 237 bp overlap

ChIP K562 ENCFF059YCJ 406 bp overlap

STAT1 1 dataset

ChIP HeLa-S3 ENCSR000EZK.STAT1.HeLa-S3 216 bp overlap

TAL1 13 datasets

ChIP K-562 ENCSR000EHB.TAL1.K-562 601 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 255 bp overlap

ChIP K-562 ENCSR106FRG.TAL1.K-562 230 bp overlap

ChIP K-562_MYO1D-Non-hub_KO GSE107726.TAL1.K-562_MYO1D-Non-hub_KO 221 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 233 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 235 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 232 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 227 bp overlap

ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 226 bp overlap

ChIP K562 ENCFF620GMX 309 bp overlap

ChIP K562 ENCFF620GMX 283 bp overlap

ChIP K562 ENCFF661CCK 277 bp overlap

ChIP K562 ENCFF661CCK 277 bp overlap

TCF12 3 datasets

ChIP K-562 ENCSR744WOO.TCF12.K-562 344 bp overlap

ChIP K562 ENCFF909RDY 397 bp overlap

ChIP K562 ENCFF931DJY 287 bp overlap

TCF3 2 datasets

ChIP K-562 ENCSR970OJY.TCF3.K-562 338 bp overlap

ChIP K562 ENCFF319QZT 201 bp overlap

TEAD4 1 dataset

ChIP K562 ENCFF673NIK 365 bp overlap

TRIM24 5 datasets

ChIP K-562 ENCSR907MZR.TRIM24.K-562 51 bp overlap

ChIP K-562 ENCSR907MZR.TRIM24.K-562 407 bp overlap

ChIP K-562 ENCSR957LDM.TRIM24.K-562 326 bp overlap

ChIP K562 ENCFF284DKY 161 bp overlap

ChIP K562 ENCFF616RIL 230 bp overlap

TRIM28 7 datasets

ChIP K-562 ENCSR474CVP.TRIM28.K-562 57 bp overlap

ChIP K-562 ENCSR000EVY.TRIM28.K-562 221 bp overlap

ChIP K-562 ENCSR000BRW.TRIM28.K-562 50 bp overlap

ChIP K-562 ENCSR474CVP.TRIM28.K-562 363 bp overlap

ChIP K562 ENCFF172UPN 199 bp overlap

ChIP K562 ENCFF671NCI 455 bp overlap

ChIP K562 ENCFF671NCI 655 bp overlap

USF1 9 datasets

ChIP GM12878 ENCSR000BGI.USF1.GM12878 137 bp overlap

ChIP HCT-116 ENCSR000BVK.USF1.HCT-116 241 bp overlap

ChIP HCT116 ENCFF330PYP 305 bp overlap

ChIP Hep-G2 ENCSR000BGM.USF1.Hep-G2 116 bp overlap

ChIP HepG2 ENCFF807KYJ 201 bp overlap

ChIP Ishikawa ENCSR000BSX.USF1.Ishikawa 133 bp overlap

ChIP K-562 ENCSR000BKT.USF1.K-562 175 bp overlap

ChIP K562 ENCFF202SFC 347 bp overlap

ChIP SK-N-SH ENCSR000BMF.USF1.SK-N-SH 209 bp overlap

USF2 3 datasets

ChIP GM12878 GSE97661.USF2.GM12878 298 bp overlap

ChIP Hep-G2 GSE97661.USF2.Hep-G2 229 bp overlap

ChIP IMR-90 ENCSR513UQG.USF2.IMR-90 117 bp overlap

ChIP GM12878 ENCFF908JTL 148 bp overlap

ChIP GM12891 ENCSR000BKJ.YY1.GM12891 148 bp overlap

ChIP GM12892 ENCFF802MHJ 291 bp overlap

ChIP GM12892 ENCSR000BLT.YY1.GM12892 188 bp overlap

ChIP Ishikawa ENCSR000BSY.YY1.Ishikawa 112 bp overlap

ChIP K-562 ENCSR000BKU.YY1.K-562 159 bp overlap

ChIP K-562 ENCSR000BMH.YY1.K-562 132 bp overlap

ZBTB2 2 datasets

ChIP GM12878 GSE97661.ZBTB2.GM12878 188 bp overlap

ChIP Hep-G2 GSE97661.ZBTB2.Hep-G2 148 bp overlap

ZEB2 2 datasets

ChIP K562 ENCFF975RXS 243 bp overlap

ChIP K562 ENCFF975RXS 442 bp overlap

ZNF280A 2 datasets

ChIP HEK293 GSE76494.ZNF280A.HEK293 64 bp overlap

ChIP K562 ENCFF706EWX 145 bp overlap

ZNF280B 1 dataset

ChIP K562 ENCFF568RSS 136 bp overlap

ZNF280D 1 dataset

ChIP HEK293 ENCFF420AXB 140 bp overlap

ZNF418 1 dataset

Motif DE_72h DE_72h-ZNF418_MA1980.1 15 bp overlap

ZNF510 1 dataset

ChIP HEK293 ENCFF202BSY 70 bp overlap

ZNF518A 1 dataset

ChIP HEK293 ENCFF892ULS 192 bp overlap

ZNF529 1 dataset

ChIP HEK293 ENCFF090MHG 141 bp overlap

ZNF547 1 dataset

Motif DE_72h DE_72h-ZNF547_MA2334.1 13 bp overlap

ZNF85 1 dataset

Motif DE_72h DE_72h-ZNF85_MA1720.2 12 bp overlap

ZNF850 1 dataset

ChIP HepG2 ENCFF671RTH 170 bp overlap

ZNF865 1 dataset

ChIP HepG2 ENCFF472KAQ 214 bp overlap

ZNF92 1 dataset

ChIP retina_pigment GSE60024.ZNF92.retina_pigment 50 bp overlap

ZSCAN4 2 datasets

ChIP HEK293 ENCFF381BKT 237 bp overlap

ChIP HEK293 ENCSR211GNP.ZSCAN4.HEK293 362 bp overlap