This gene encodes a krueppel C2H2-type zinc-finger protein family member. The encoded protein is expressed in several cancer cell types and may be a biomarker for early diagnosis of these cancers. [provided by RefSeq, Sep 2015]
Transcription factors with Perturb-seq knockdown data for ZNF510. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF510 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF510, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr9:96,543,037–96,543,508 | 234.8 kb | Distal (>10kb) Multiome | 76 | |
| chr9:96,566,442–96,567,471 | 211.1 kb | Distal (>10kb) Multiome | 819 | |
| chr9:96,618,860–96,620,237 | 158.3 kb | Distal (>10kb) Multiome | 570 | |
| chr9:96,620,809–96,621,291 | 157.0 kb | Distal (>10kb) Multiome | 143 | |
| chr9:96,654,449–96,655,707 | 122.8 kb | Distal (>10kb) Multiome | 706 | |
| chr9:96,686,688–96,687,337 | 91.1 kb | Distal (>10kb) Multiome | 253 | |
| chr9:96,777,772–96,778,352 | 18 bp | At TSS Multiome | 632 | |
| chr9:96,854,007–96,854,748 | 76.5 kb | Distal (>10kb) Multiome | 699 | |
| chr9:96,875,314–96,876,157 | 97.8 kb | Distal (>10kb) Multiome | 643 | |
| chr9:97,013,175–97,013,888 | 235.5 kb | Distal (>10kb) Multiome | 273 | |
| chr9:97,038,375–97,039,810 | 261.2 kb | Distal (>10kb) Multiome | 639 | |
| chr9:97,051,679–97,052,459 | 273.9 kb | Distal (>10kb) Multiome | 224 |
Genomic view of the ZNF510 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.