chr12 : 74,539,305 – 74,540,076

771 bp 124 TFs 2 linked genes

This 771 bp open chromatin element is linked to ENSG00000257386 and ATXN7L3B and is bound by 124 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000257386		672 bp	At TSS	Proximity
ATXN7L3B		1.5 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

124 transcription factors

AR 1 dataset

ChIP LNCaP GSE80256.AR.LNCaP 276 bp overlap

ASH2L 1 dataset

ChIP Hep-G2 ENCSR508LMH.ASH2L.Hep-G2 297 bp overlap

ATF2 1 dataset

Motif DE_60h DE_60h-ATF2_MA1632.2 10 bp overlap

BACH2 1 dataset

ChIP OCI-Ly7 GSE69558.BACH2.OCI-Ly7 72 bp overlap

BHLHE22 2 datasets

ChIP CAL-1 GSE43876.BHLHE22.CAL-1 126 bp overlap

Motif DE_60h DE_60h-BHLHE22_MA1635.2 6 bp overlap

BRD2 1 dataset

ChIP SK-MEL-147 GSE94488.BRD2.SK-MEL-147 107 bp overlap

BRD4 4 datasets

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 216 bp overlap

ChIP MPNST_PDJQ GSE62499.BRD4.MPNST_PDJQ 220 bp overlap

ChIP RH4 GSE83726.BRD4.RH4 229 bp overlap

ChIP RH4_shCHD4 GSE140115.BRD4.RH4_shCHD4 249 bp overlap

Bhlha15 1 dataset

Motif DE_60h DE_60h-Bhlha15_MA1472.3 8 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 277 bp overlap

CREBBP 2 datasets

ChIP MCF-7 ERP000901.CREBBP.MCF-7 163 bp overlap

ChIP PC-3_GDC-resist GSE147455.CREBBP.PC-3_GDC-resist 130 bp overlap

CRX 1 dataset

ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 355 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 309 bp overlap

CTCF 5 datasets

Motif DE_12h DE_12h-CTCF_MA0139.2 15 bp overlap

Motif DE_60h DE_60h-CTCF_MA0139.2 15 bp overlap

ChIP DOHH2 ENCSR084RDK.CTCF.DOHH2 88 bp overlap

ChIP K-562_MonoC GSE137216.CTCF.K-562_MonoC 86 bp overlap

ChIP RH4 GSE83726.CTCF.RH4 148 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF364PUR 107 bp overlap

DNMT1 2 datasets

ChIP K-562 ENCSR987PBI.DNMT1.K-562 99 bp overlap

ChIP K562 ENCFF742HMD 226 bp overlap

DPF2 2 datasets

ChIP K-562 ENCSR219BXP.DPF2.K-562 62 bp overlap

ChIP K562 ENCFF739JDE 113 bp overlap

E2F4 1 dataset

ChIP K-562 ENCSR000EWL.E2F4.K-562 137 bp overlap

E2F6 1 dataset

ChIP K-562 ENCSR000BLI.E2F6.K-562 133 bp overlap

ESR1 1 dataset

ChIP MCF-7_E2 ERP000901.ESR1.MCF-7_E2 111 bp overlap

ESR1_Y537N 1 dataset

ChIP MCF-7_dox_E2 GSE94493.ESR1_Y537N.MCF-7_dox_E2 78 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 345 bp overlap

FERD3L 2 datasets

Motif DE_60h DE_60h-FERD3L_MA1485.1 14 bp overlap

FEZF2 2 datasets

Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap

Motif DE_60h DE_60h-FEZF2_MA2341.1 8 bp overlap

FIGLA 1 dataset

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

FOS 1 dataset

ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 317 bp overlap

FOXB1 1 dataset

Motif DE_60h DE_60h-FOXB1_MA0845.1 11 bp overlap

FOXC1 1 dataset

Motif DE_60h DE_60h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif DE_60h DE_60h-FOXC2_MA0846.2 11 bp overlap

FOXD2 1 dataset

Motif DE_60h DE_60h-FOXD2_MA0847.4 11 bp overlap

FOXE1 1 dataset

Motif DE_60h DE_60h-FOXE1_MA1487.3 12 bp overlap

FOXP1 1 dataset

ChIP LNCaP GSE62492.FOXP1.LNCaP 113 bp overlap

Foxl2 1 dataset

Motif DE_60h DE_60h-Foxl2_MA1607.2 10 bp overlap

GATA1 1 dataset

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 138 bp overlap

GATA2 1 dataset

ChIP K-562 ENCSR000EWG.GATA2.K-562 136 bp overlap

GLIS1 3 datasets

ChIP HEK293 ENCFF299RSE 115 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 209 bp overlap

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 274 bp overlap

GLIS2 2 datasets

Motif DE_12h DE_12h-GLIS2_MA0736.1 14 bp overlap

Motif DE_60h DE_60h-GLIS2_MA0736.1 14 bp overlap

GLIS3 2 datasets

Motif DE_12h DE_12h-GLIS3_MA0737.1 14 bp overlap

Motif DE_60h DE_60h-GLIS3_MA0737.1 14 bp overlap

HAND2 2 datasets

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

Motif DE_60h DE_60h-HAND2_MA1638.2 6 bp overlap

HBP1 1 dataset

ChIP HepG2 ENCFF512UDH 419 bp overlap

HDAC1 3 datasets

ChIP MCF-7_ARID1A-KO_4-OHT_clone14 GSE123284.HDAC1.MCF-7_ARID1A-KO_4-OHT_clone14 214 bp overlap

ChIP MCF-7_parental GSE123284.HDAC1.MCF-7_parental 345 bp overlap

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.HDAC1.MCF-7_parental_4-hydroxytamoxifen 771 bp overlap

HDAC2 2 datasets

ChIP K-562 ENCSR893WSB.HDAC2.K-562 164 bp overlap

ChIP K-562 ENCSR075HTM.HDAC2.K-562 208 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 71 bp overlap

HDAC8 1 dataset

ChIP K-562 ENCSR835TCD.HDAC8.K-562 58 bp overlap

HDGF 2 datasets

ChIP K-562 ENCSR197ALX.HDGF.K-562 771 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 168 bp overlap

HLTF 1 dataset

ChIP K562 ENCFF783OCM 179 bp overlap

HMBOX1 3 datasets

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 320 bp overlap

ChIP K562 ENCFF055GAZ 317 bp overlap

ChIP K562 ENCFF055GAZ 516 bp overlap

HMGB2 1 dataset

ChIP HUVEC-C GSE98245.HMGB2.HUVEC-C 205 bp overlap

Hand1::Tcf3 2 datasets

Motif DE_12h DE_12h-Hand1Tcf3_MA0092.2 9 bp overlap

Motif DE_60h DE_60h-Hand1Tcf3_MA0092.2 9 bp overlap

ID3 2 datasets

ChIP K-562 ENCSR005NMT.ID3.K-562 260 bp overlap

ChIP K562 ENCFF170RNI 71 bp overlap

IRF2 1 dataset

ChIP keratinocyte_DOX GSE135677.IRF2.keratinocyte_DOX 216 bp overlap

JUN 1 dataset

Motif DE_60h DE_60h-JUN_MA0488.2 10 bp overlap

JUND 1 dataset

Motif DE_60h DE_60h-JUND_MA0492.2 11 bp overlap

KAT7 1 dataset

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 771 bp overlap

L3MBTL2 2 datasets

ChIP HEK293T ENCFF482NJV 249 bp overlap

ChIP HEK293T ENCSR862PNL.L3MBTL2.HEK293T 80 bp overlap

MAFG 1 dataset

ChIP K-562 ENCSR818DQV.MAFG.K-562 119 bp overlap

MAX 3 datasets

ChIP K562 ENCFF398VJM 90 bp overlap

ChIP MDA-MB-231 GSE127192.MAX.MDA-MB-231 76 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 207 bp overlap

MLLT1 1 dataset

ChIP K-562 ENCSR107GRP.MLLT1.K-562 397 bp overlap

MTA3 2 datasets

ChIP K-562 ENCSR914NEI.MTA3.K-562 489 bp overlap

ChIP K-562 ENCSR180NCY.MTA3.K-562 771 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 232 bp overlap

MYCN 2 datasets

ChIP COG-N-415 GSE138295.MYCN.COG-N-415 62 bp overlap

ChIP RH4 GSE83726.MYCN.RH4 103 bp overlap

MYF5 1 dataset

Motif DE_60h DE_60h-MYF5_MA1641.2 8 bp overlap

MYOD1 2 datasets

Motif DE_60h DE_60h-MYOD1_MA0499.3 9 bp overlap

ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 134 bp overlap

MYOG 1 dataset

ChIP RH4 GSE83726.MYOG.RH4 153 bp overlap

NCAPH2 1 dataset

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 257 bp overlap

NELFE 1 dataset

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 203 bp overlap

NEUROD1 5 datasets

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 229 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 133 bp overlap

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 303 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 312 bp overlap

Motif DE_60h DE_60h-NEUROD1_MA1109.2 8 bp overlap

NFE2 2 datasets

ChIP K-562 ENCSR000FCC.NFE2.K-562 110 bp overlap

ChIP K-562 ENCSR552YGL.NFE2.K-562 80 bp overlap

NFE2L1 1 dataset

ChIP K562 ENCFF138UHK 61 bp overlap

NFKBIZ 1 dataset

ChIP Hep-G2 ENCSR235OVI.NFKBIZ.Hep-G2 127 bp overlap

NKRF 1 dataset

ChIP K562 ENCFF815TQL 257 bp overlap

NKX2-2 1 dataset

Motif DE_60h DE_60h-NKX2-2_MA1645.2 8 bp overlap

NRF1 1 dataset

ChIP HeLa-S3 GSE108856.NRF1.HeLa-S3 499 bp overlap

NRIP1 1 dataset

ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 238 bp overlap

Neurod2 2 datasets

Motif DE_60h DE_60h-Neurod2_MA0668.3 8 bp overlap

Motif DE_60h DE_60h-Neurod2_MA1993.2 6 bp overlap

Olig2 1 dataset

Motif DE_60h DE_60h-Olig2_MA1997.2 6 bp overlap

PAF1 1 dataset

ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 261 bp overlap

PKNOX1 2 datasets

ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 84 bp overlap

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 149 bp overlap

POLR2A 5 datasets

ChIP H1 ENCFF566JSR 232 bp overlap

ChIP HeLa-S3 ENCFF773DNG 412 bp overlap

ChIP IMR-90 ENCFF672YWV 605 bp overlap

ChIP erythroblast ENCFF498VMR 751 bp overlap

ChIP erythroblast ENCFF498VMR 290 bp overlap

PRDM1 1 dataset

ChIP HEK293 ENCFF302TBP 421 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 230 bp overlap

PRDM9 1 dataset

Motif DE_60h DE_60h-PRDM9_MA1723.2 20 bp overlap

Ptf1A 1 dataset

Motif DE_60h DE_60h-Ptf1A_MA1619.2 8 bp overlap

RAD21 1 dataset

ChIP RH4 GSE83726.RAD21.RH4 340 bp overlap

RBFOX2 4 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 285 bp overlap

ChIP K562 ENCFF196WTG 408 bp overlap

ChIP K562 ENCFF196WTG 555 bp overlap

ChIP K562 ENCFF967GRF 589 bp overlap

RELA 2 datasets

ChIP HDF_NUTLIN GSE77225.RELA.HDF_NUTLIN 125 bp overlap

ChIP HDF_NUTLIN GSE77225.RELA.HDF_NUTLIN 163 bp overlap

REST 1 dataset

Motif DE_60h DE_60h-REST_MA0138.3 20 bp overlap

SCRT2 1 dataset

ChIP HEK293 ENCFF711QQB 413 bp overlap

SMAD2 2 datasets

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 429 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 343 bp overlap

SMARCA4 3 datasets

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 210 bp overlap

ChIP K562 ENCFF506JCB 289 bp overlap

ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 290 bp overlap

SMARCC1 1 dataset

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 399 bp overlap

SMARCC2 1 dataset

ChIP K-562 ENCSR519WMW.SMARCC2.K-562 121 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 133 bp overlap

SNAI2 1 dataset

ChIP RD_shSNAI2 GSE137168.SNAI2.RD_shSNAI2 160 bp overlap

STAG1 1 dataset

ChIP MCF-7_E2_SHCTCF ERP000209.STAG1.MCF-7_E2_SHCTCF 126 bp overlap

STAT1_pS727 2 datasets

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 361 bp overlap

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 157 bp overlap

SUPT5H 3 datasets

ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 202 bp overlap

ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 142 bp overlap

ChIP HCT-116_pThr806 GSE138548.SUPT5H.HCT-116_pThr806 336 bp overlap

TCF4 3 datasets

ChIP CAL-1 GSE76147.TCF4.CAL-1 174 bp overlap

Motif DE_60h DE_60h-TCF4_MA0830.3 8 bp overlap

ChIP GEN2-2 GSE76147.TCF4.GEN2-2 152 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 425 bp overlap

TRIM24 1 dataset

ChIP K-562 ENCSR907MZR.TRIM24.K-562 141 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 302 bp overlap

Tcf12 1 dataset

Motif DE_60h DE_60h-Tcf12_MA0521.3 6 bp overlap

Tcf21 1 dataset

Motif DE_60h DE_60h-Tcf21_MA0832.2 10 bp overlap

Twist2 1 dataset

Motif DE_60h DE_60h-Twist2_MA0633.3 6 bp overlap

YY1 2 datasets

ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 490 bp overlap

ChIP RH4_DMSO-6H GSE116344.YY1.RH4_DMSO-6H 186 bp overlap

ZEB1 1 dataset

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

ZFX 2 datasets

ChIP HEK293T_22Rv1 GSE145160.ZFX.HEK293T_22Rv1 144 bp overlap

ChIP K562 ENCFF169LZT 106 bp overlap

ZIC1 2 datasets

Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap

Motif DE_60h DE_60h-ZIC1_MA0696.1 14 bp overlap

ZIC2 1 dataset

ChIP HEK293 ENCFF033NQQ 393 bp overlap

ZIC4 2 datasets

Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap

Motif DE_60h DE_60h-ZIC4_MA0751.2 14 bp overlap

ZIC5 2 datasets

Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap

Motif DE_60h DE_60h-ZIC5_MA1584.2 15 bp overlap

ZNF189 1 dataset

ChIP HEK293 ENCSR163RYW.ZNF189.HEK293 244 bp overlap

ZNF24 1 dataset

ChIP K-562 ENCSR695EQB.ZNF24.K-562 107 bp overlap

ZNF257 1 dataset

Motif DE_60h DE_60h-ZNF257_MA1710.2 10 bp overlap

ZNF320 1 dataset

Motif DE_60h DE_60h-ZNF320_MA1976.2 20 bp overlap

ZNF35 1 dataset

ChIP HEK293 GSE76494.ZNF35.HEK293 155 bp overlap

ZNF407 1 dataset

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 304 bp overlap

ZNF485 1 dataset

ChIP HEK293T GSE78099.ZNF485.HEK293T 323 bp overlap

ZNF598 1 dataset

ChIP Hep-G2 ENCSR173NAL.ZNF598.Hep-G2 502 bp overlap

ZNF639 2 datasets

ChIP K-562 ENCSR949NVY.ZNF639.K-562 54 bp overlap

ChIP K562 ENCFF267NLX 173 bp overlap

ZNF750 1 dataset

ChIP keratinocyte_diff GSE57702.ZNF750.keratinocyte_diff 280 bp overlap

ZNF770 2 datasets

Motif DE_12h DE_12h-ZNF770_MA2099.1 8 bp overlap

Motif DE_60h DE_60h-ZNF770_MA2099.1 8 bp overlap

ZNF816 1 dataset

Motif DE_60h DE_60h-ZNF816_MA1719.2 15 bp overlap