chr10:11,869,855–11,870,414

chr10 : 11,869,855 – 11,870,414

559 bp 105 TFs 7 linked genes

This 559 bp open chromatin element is linked to 7 target genes and is bound by 105 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PROSER2-AS1		4.4 kb	Proximal	Proximity
PROSER2		46.9 kb	Distal	Multiome
ECHDC3		127.8 kb	Distal	Multiome
UPF2		172.6 kb	Distal	Multiome
DHTKD1		198.8 kb	Distal	Multiome
USP6NL		258.6 kb	Distal	Multiome
SEC61A2		259.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

105 transcription factors

AGO1 2 datasets

ChIP K-562 ENCSR641BSL.AGO1.K-562 147 bp overlap

ChIP K-562 GSE120104.AGO1.K-562 147 bp overlap

AGO2 2 datasets

ChIP HepG2 ENCFF252VFI 235 bp overlap

ChIP HepG2 ENCFF773YDL 235 bp overlap

ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 307 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 126 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 140 bp overlap

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 468 bp overlap

ChIP H1 ENCFF399KAM 252 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 203 bp overlap

ChIP WA01 GSE104690.BCOR.WA01 444 bp overlap

ChIP foreskin_NHM1-5 GSE94488.BRD2.foreskin_NHM1-5 528 bp overlap

BRD4 12 datasets

ChIP COLO-741 GSE73319.BRD4.COLO-741 85 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 252 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 559 bp overlap

ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 67 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 558 bp overlap

ChIP hESC GSE33281.BRD4.hESC 74 bp overlap

ChIP hESC GSE33281.BRD4.hESC 105 bp overlap

ChIP keratinocyte GSE140992.BRD4.keratinocyte 559 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 101 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 261 bp overlap

ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 263 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 555 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 109 bp overlap

ChIP hMSC GSE117084.CBX4.hMSC 190 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 209 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231 GSE112444.CDKN1B.MDA-MB-231 65 bp overlap

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 195 bp overlap

ChIP T-47D_ETOH_5 GSE62428.CHD8.T-47D_ETOH_5 204 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 242 bp overlap

CTCF 3 datasets

ChIP T-47D_NaCl-isotonic GSE111923.CTCF.T-47D_NaCl-isotonic 293 bp overlap

ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 500 bp overlap

ChIP T-47D_NaCl-triptolide GSE111923.CTCF.T-47D_NaCl-triptolide 347 bp overlap

CTCFL 2 datasets

ChIP K-562 GSE70764.CTCFL.K-562 166 bp overlap

ChIP delta-47 GSE70764.CTCFL.delta-47 353 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF274GAT 88 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 450 bp overlap

ChIP mesenchymal GSE77260.E2F1.mesenchymal 219 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 451 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 191 bp overlap

Motif DE_12h DE_12h-EBF1_MA0154.5 11 bp overlap

ChIP ME-1 GSE46044.ELF1.ME-1 372 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 559 bp overlap

ChIP K-562 GSE23730.ERG.K-562 250 bp overlap

ChIP K-562 GSE23730.ERG.K-562 213 bp overlap

ChIP K-562_DOX GSE23730.ERG.K-562_DOX 317 bp overlap

ChIP MCF-7 GSE23730.ERG.MCF-7 217 bp overlap

ESR1 8 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 143 bp overlap

ChIP Ishikawa GSE99905.ESR1.Ishikawa 331 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 386 bp overlap

ChIP MCF-7_Y537S_DMSO GSE148277.ESR1.MCF-7_Y537S_DMSO 221 bp overlap

ChIP MCF-7_estradiol_45min_ChIP-and-reChIP GSE99626.ESR1.MCF-7_estradiol_45min_ChIP-and-reChIP 275 bp overlap

ChIP breast_tumor_Male_14 GSE104399.ESR1.breast_tumor_Male_14 195 bp overlap

ChIP breast_tumor_Male_14 GSE104399.ESR1.breast_tumor_Male_14 216 bp overlap

ChIP breast_tumor_Male_19 GSE104399.ESR1.breast_tumor_Male_19 410 bp overlap

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 260 bp overlap

Motif DE_12h DE_12h-Ebf4_MA2122.1 11 bp overlap

FLI1 2 datasets

ChIP ME-1 GSE46044.FLI1.ME-1 254 bp overlap

ChIP UAE_ZINC GSE23730.FLI1.UAE_ZINC 178 bp overlap

FOXA1 2 datasets

ChIP breast-cancer_heregulin-Herceptin-ICI GSE101407.FOXA1.breast-cancer_heregulin-Herceptin-ICI 432 bp overlap

ChIP breast_tumor_Male_19 GSE104399.FOXA1.breast_tumor_Male_19 224 bp overlap

FOXL2 1 dataset

ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 90 bp overlap

GABPA 2 datasets

ChIP WA01 ENCSR000BIW.GABPA.WA01 184 bp overlap

ChIP WA01 ENCSR000BIW.GABPA.WA01 264 bp overlap

GATA2 1 dataset

ChIP SKH1 GSE87283.GATA2.SKH1 130 bp overlap

GATA3 1 dataset

ChIP breast_tumor_Male_21 GSE104399.GATA3.breast_tumor_Male_21 130 bp overlap

GATA6 1 dataset

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 259 bp overlap

GTF2F1 1 dataset

ChIP K-562 ENCSR377BLZ.GTF2F1.K-562 51 bp overlap

HEXIM1 2 datasets

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 120 bp overlap

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 309 bp overlap

Motif DE_12h DE_12h-HIC2_MA0738.2 6 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 251 bp overlap

HMGB1 1 dataset

ChIP HUVEC-C GSE98245.HMGB1.HUVEC-C 245 bp overlap

JARID2 1 dataset

ChIP AMIPS6 GSE48516.JARID2.AMIPS6 256 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 307 bp overlap

ChIP MCF-7_BD610326 GSE128445.JUN.MCF-7_BD610326 211 bp overlap

KDM6B 1 dataset

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 186 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 559 bp overlap

ChIP keratinocyte_diff GSE57702.KLF4.keratinocyte_diff 181 bp overlap

ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 203 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 103 bp overlap

ChIP melanocyte_CTR GSE50681.MITF.melanocyte_CTR 205 bp overlap

NANOG 2 datasets

ChIP WA01 ERP004238.NANOG.WA01 211 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 291 bp overlap

NCAPH2 2 datasets

ChIP HEK293 GSE97540.NCAPH2.HEK293 559 bp overlap

ChIP IMR-90_Bethyl275_G GSE118494.NCAPH2.IMR-90_Bethyl275_G 202 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 559 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 559 bp overlap

OGG1 2 datasets

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 76 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 133 bp overlap

OLIG2 1 dataset

ChIP brain-prefrontal-cortex_2017014 GSE129039.OLIG2.brain-prefrontal-cortex_2017014 461 bp overlap

PCBP1 5 datasets

ChIP K-562 GSE120104.PCBP1.K-562 251 bp overlap

ChIP K-562 ENCSR052PTN.PCBP1.K-562 245 bp overlap

ChIP K562 ENCFF121LOV 216 bp overlap

ChIP K562 ENCFF382QWQ 222 bp overlap

ChIP K562 ENCFF382QWQ 423 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 559 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 559 bp overlap

POLR2A 3 datasets

ChIP adrenal gland ENCFF843OBJ 476 bp overlap

ChIP adrenal gland ENCFF843OBJ 276 bp overlap

ChIP thyroid gland ENCFF979LRR 491 bp overlap

POLR2G 3 datasets

ChIP K562 ENCFF047BLG 184 bp overlap

ChIP K562 ENCFF047BLG 323 bp overlap

ChIP K562 ENCFF648YPL 184 bp overlap

POU5F1 8 datasets

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 188 bp overlap

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 300 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 559 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 547 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 287 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 169 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 106 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 318 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 559 bp overlap

ChIP TSU-1621MT GSE60477.RARA.TSU-1621MT 68 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 345 bp overlap

RBFOX2 2 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 56 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 105 bp overlap

RBM14 1 dataset

ChIP K-562 ENCSR423FCW.RBM14.K-562 108 bp overlap

RBM22 3 datasets

ChIP K-562 GSE120104.RBM22.K-562 559 bp overlap

ChIP K-562 ENCSR848AOP.RBM22.K-562 108 bp overlap

ChIP K-562 ENCSR848AOP.RBM22.K-562 332 bp overlap

RNF2 3 datasets

ChIP WA09 GSE105028.RNF2.WA09 494 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 474 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 559 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 559 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 559 bp overlap

RUNX1 6 datasets

ChIP AML_Blast GSE60130.RUNX1.AML_Blast 153 bp overlap

ChIP CD34 GSE64862.RUNX1.CD34 153 bp overlap

ChIP Jurkat GSE85524.RUNX1.Jurkat 443 bp overlap

ChIP ME-1 GSE46044.RUNX1.ME-1 530 bp overlap

ChIP SKNO-1 GSE23730.RUNX1.SKNO-1 179 bp overlap

ChIP SKNO-1 GSE23730.RUNX1.SKNO-1 218 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 261 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 535 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 516 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 312 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 275 bp overlap

SMAD2_3 1 dataset

ChIP ESC S23-ESC-d0-SMAD2_3-exp1 355 bp overlap

SMARCC1 1 dataset

ChIP ESC S25-ESC-d0-BAF155-exp1 317 bp overlap

SMC1 3 datasets

ChIP DKO GSE131606.SMC1.DKO 79 bp overlap

ChIP DKO GSE131606.SMC1.DKO 268 bp overlap

ChIP IMR-90_OIS GSE118494.SMC1.IMR-90_OIS 226 bp overlap

SMC1A 3 datasets

ChIP primary-epidermal-keratinocyte_diff_d0 GSE84657.SMC1A.primary-epidermal-keratinocyte_diff_d0 526 bp overlap

ChIP primary-epidermal-keratinocyte_diff_d3 GSE84657.SMC1A.primary-epidermal-keratinocyte_diff_d3 292 bp overlap

ChIP primary-epidermal-keratinocyte_diff_d6 GSE84657.SMC1A.primary-epidermal-keratinocyte_diff_d6 455 bp overlap

SNAI2 2 datasets

ChIP keratinocyte_LacZ GSE55421.SNAI2.keratinocyte_LacZ 167 bp overlap

ChIP keratinocyte_SNAI2 GSE55421.SNAI2.keratinocyte_SNAI2 233 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 559 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 559 bp overlap

STAT3 2 datasets

ChIP WA01 ERP004237.STAT3.WA01 123 bp overlap

ChIP WA01 ERP004237.STAT3.WA01 282 bp overlap

SUZ12 2 datasets

ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 371 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 543 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 150 bp overlap

TAF15 2 datasets

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 100 bp overlap

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 100 bp overlap

TAL1 2 datasets

ChIP ME-1 GSE46044.TAL1.ME-1 83 bp overlap

ChIP ME-1 GSE46044.TAL1.ME-1 296 bp overlap

TARDBP 2 datasets

ChIP Hep-G2 ENCSR145CXH.TARDBP.Hep-G2 123 bp overlap

ChIP Hep-G2 GSE120104.TARDBP.Hep-G2 122 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 178 bp overlap

TBX5 3 datasets

ChIP G296S GSE85628.TBX5.G296S 395 bp overlap

ChIP G296S_2 GSE85628.TBX5.G296S_2 395 bp overlap

ChIP G296S_4 GSE85628.TBX5.G296S_4 111 bp overlap

TCF12 1 dataset

ChIP ME-1 GSE46044.TCF12.ME-1 293 bp overlap

ChIP Jurkat_RUNX1KD GSE85524.TET2.Jurkat_RUNX1KD 207 bp overlap

TFAP2A 1 dataset

Motif DE_12h DE_12h-TFAP2A_MA0810.2 11 bp overlap

TFAP2B 2 datasets

Motif DE_12h DE_12h-TFAP2B_MA0811.2 11 bp overlap

ChIP SK-N-SH ENCFF869XXQ 340 bp overlap

TFAP2C 2 datasets

Motif DE_12h DE_12h-TFAP2C_MA0524.3 11 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 206 bp overlap

TFAP2E 1 dataset

Motif DE_12h DE_12h-TFAP2E_MA1569.2 9 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 559 bp overlap

THAP1 1 dataset

Motif DE_12h DE_12h-THAP1_MA0597.3 8 bp overlap

TP63 2 datasets

ChIP keratinocyte GSE33571.TP63.keratinocyte 482 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 191 bp overlap

TRIM24 2 datasets

ChIP LNCaP-abl_ETOH GSE69331.TRIM24.LNCaP-abl_ETOH 95 bp overlap

ChIP LNCaP-abl_ETOH GSE69331.TRIM24.LNCaP-abl_ETOH 272 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 559 bp overlap

TRIM28 2 datasets

ChIP HCT-116 GSE72622.TRIM28.HCT-116 169 bp overlap

ChIP HCT-116 GSE72622.TRIM28.HCT-116 195 bp overlap

ChIP K-562 GSE111469.USF2.K-562 323 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 559 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 181 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 131 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 124 bp overlap

ZBTB14 1 dataset

Motif DE_12h DE_12h-ZBTB14_MA1650.2 8 bp overlap

ZBTB33 1 dataset

ChIP K562 ENCFF427SDV 419 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 559 bp overlap

ZNF263 1 dataset

ChIP HEK293 ENCFF336CWQ 80 bp overlap

ZNF417 1 dataset

Motif DE_12h DE_12h-ZNF417_MA1727.2 7 bp overlap

ZNF558 1 dataset

ChIP HEK293T GSE78099.ZNF558.HEK293T 287 bp overlap

ZNF610 1 dataset

Motif DE_12h DE_12h-ZNF610_MA1713.2 10 bp overlap