chr8:123,207,081–123,207,716

chr8 : 123,207,081 – 123,207,716

635 bp 96 TFs 6 linked genes

This 635 bp open chromatin element is linked to 6 target genes and is bound by 96 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
C8orf76		34.0 kb	Distal	Multiome
ZHX1		66.9 kb	Distal	Multiome
TBC1D31		134.7 kb	Distal	Multiome
DERL1		165.1 kb	Distal	Multiome
ATAD2		189.1 kb	Distal	Multiome
NTAQ1		209.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

96 transcription factors

ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 172 bp overlap

ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 254 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 387 bp overlap

ARNT::HIF1A 1 dataset

Motif DE_12h DE_12h-ARNTHIF1A_MA0259.2 5 bp overlap

ASH2L 1 dataset

ChIP H1 ENCFF399KAM 159 bp overlap

BRD2 2 datasets

ChIP THP-1_DMSO GSE138084.BRD2.THP-1_DMSO 304 bp overlap

ChIP THP-1_iBET GSE138084.BRD2.THP-1_iBET 251 bp overlap

BRD4 5 datasets

ChIP MCF-10A ERP003925.BRD4.MCF-10A 416 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 286 bp overlap

ChIP hESC GSE33281.BRD4.hESC 133 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 386 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 418 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 518 bp overlap

ChIP hMSC GSE117084.CBX4.hMSC 209 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 473 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231_p27CK-DD GSE112444.CDKN1B.MDA-MB-231_p27CK-DD 267 bp overlap

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 407 bp overlap

ChIP T-47D_ETOH_5 GSE62428.CHD8.T-47D_ETOH_5 240 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 160 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 241 bp overlap

CTCF 14 datasets

Motif ES_0h ES_0h-CTCF_MA1929.2 31 bp overlap

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP HT-1080_CBL0137-6h GSE122462.CTCF.HT-1080_CBL0137-6h 188 bp overlap

ChIP Hep-G2 ENCSR000DLS.CTCF.Hep-G2 79 bp overlap

ChIP MCF-7 ENCFF414SZG 191 bp overlap

ChIP MCF-7 ENCFF424NQR 191 bp overlap

ChIP MCF-7 ENCFF844STM 191 bp overlap

ChIP T-47D_NaCl-isotonic GSE111923.CTCF.T-47D_NaCl-isotonic 260 bp overlap

ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 467 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 123 bp overlap

ChIP THP-1_Pam3csk-000m-Flavo-000m GSE103477.CTCF.THP-1_Pam3csk-000m-Flavo-000m 168 bp overlap

ChIP anterior-temporal-cortex_adult GSE116825.CTCF.anterior-temporal-cortex_adult 152 bp overlap

ChIP hiPSC_IB12 GSE106870.CTCF.hiPSC_IB12 209 bp overlap

ChIP islet ERP004003.CTCF.islet 193 bp overlap

CTCFL 1 dataset

ChIP K-562 GSE70764.CTCFL.K-562 313 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF262VBH 264 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 334 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 270 bp overlap

ChIP A-375 GSE116190.EGR1.A-375 186 bp overlap

EPAS1 1 dataset

Motif DE_12h DE_12h-EPAS1_MA2325.1 9 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 483 bp overlap

ChIP MCF-7 GSE23730.ERG.MCF-7 495 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 477 bp overlap

ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 213 bp overlap

ESR1 11 datasets

ChIP Ishikawa GSE99905.ESR1.Ishikawa 477 bp overlap

ChIP Ishikawa_EnhiE2 GSE99905.ESR1.Ishikawa_EnhiE2 279 bp overlap

ChIP MCF-7 GSE48930.ESR1.MCF-7 171 bp overlap

ChIP MCF-7 GSE148277.ESR1.MCF-7 318 bp overlap

ChIP MCF-7_Fulv GSE115607.ESR1.MCF-7_Fulv 225 bp overlap

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 336 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 396 bp overlap

ChIP MCF-7_Y537S_DMSO GSE148277.ESR1.MCF-7_Y537S_DMSO 510 bp overlap

ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 284 bp overlap

ChIP MCF-7_estradiol-aldosterone_45min GSE99626.ESR1.MCF-7_estradiol-aldosterone_45min 241 bp overlap

ChIP MCF-7_estradiol_45min_ChIP-and-reChIP GSE99626.ESR1.MCF-7_estradiol_45min_ChIP-and-reChIP 302 bp overlap

ETS1 2 datasets

ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 139 bp overlap

ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 249 bp overlap

ETV6 3 datasets

ChIP K-562 ENCSR124BJR.ETV6.K-562 76 bp overlap

ChIP WTC11 ENCFF812SCD 58 bp overlap

ChIP WTC11 ENCFF812SCD 288 bp overlap

FERD3L 1 dataset

Motif DE_12h DE_12h-FERD3L_MA1485.1 14 bp overlap

FLI1 4 datasets

ChIP CTV-1_DSG GSE128835.FLI1.CTV-1_DSG 159 bp overlap

ChIP ME-1 GSE46044.FLI1.ME-1 254 bp overlap

ChIP UAE GSE23730.FLI1.UAE 608 bp overlap

ChIP UAE_ZINC GSE23730.FLI1.UAE_ZINC 614 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 373 bp overlap

FOXP1 1 dataset

ChIP WTC11 ENCFF338WGC 401 bp overlap

HCFC1R1 1 dataset

ChIP cartilage GSE100311.HCFC1R1.cartilage 484 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 553 bp overlap

HIF1A 2 datasets

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 447 bp overlap

Motif DE_12h DE_12h-HIF1A_MA1106.2 6 bp overlap

HNRNPK 3 datasets

ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 334 bp overlap

ChIP Hep-G2 ENCSR519QAA.HNRNPK.Hep-G2 303 bp overlap

ChIP HepG2 ENCFF826MXP 81 bp overlap

HOXA3 1 dataset

ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 213 bp overlap

ChIP MCF-7_hyperthermia-15min GSE137558.HSF1.MCF-7_hyperthermia-15min 130 bp overlap

JARID2 1 dataset

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 403 bp overlap

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 422 bp overlap

KDM5B 2 datasets

ChIP MCF-7 GSE46055.KDM5B.MCF-7 186 bp overlap

ChIP MCF-7 GSE46055.KDM5B.MCF-7 188 bp overlap

KDM6B 1 dataset

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 226 bp overlap

KLF15 1 dataset

Motif ES_0h ES_0h-KLF15_MA1513.2 8 bp overlap

KLF17 1 dataset

Motif DE_12h DE_12h-KLF17_MA1514.2 14 bp overlap

MAF1 2 datasets

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 353 bp overlap

ChIP THP-1_monocytes GSE96800.MAF1.THP-1_monocytes 153 bp overlap

ChIP H1 ENCFF914VQY 201 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 145 bp overlap

ChIP WTC11 ENCFF223QFY 436 bp overlap

MED1 2 datasets

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 350 bp overlap

ChIP HCT-116_thaps GSE121798.MED1.HCT-116_thaps 370 bp overlap

ChIP CD34 GSE85488.MYC.CD34 117 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 228 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 253 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 450 bp overlap

Motif DE_12h DE_12h-NFYB_MA0502.3 9 bp overlap

NOTCH1 2 datasets

ChIP HCC1599 GSE116871.NOTCH1.HCC1599 438 bp overlap

ChIP HCC1599_GSI GSE116871.NOTCH1.HCC1599_GSI 378 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 381 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 432 bp overlap

NR3C1 1 dataset

ChIP breast_tumor_Male_1 GSE104399.NR3C1.breast_tumor_Male_1 192 bp overlap

OGG1 3 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 500 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 540 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 497 bp overlap

PCBP1 3 datasets

ChIP HepG2 ENCFF604TPT 230 bp overlap

ChIP K-562 ENCSR052PTN.PCBP1.K-562 329 bp overlap

ChIP K-562 GSE120104.PCBP1.K-562 321 bp overlap

ChIP MCF-7_PROG GSE68355.PGR.MCF-7_PROG 95 bp overlap

POLR2A 1 dataset

ChIP K562 ENCFF214YGX 177 bp overlap

POLR2G 2 datasets

ChIP K562 ENCFF047BLG 616 bp overlap

ChIP K562 ENCFF648YPL 616 bp overlap

POU2F1 2 datasets

ChIP T-47D GSE148277.POU2F1.T-47D 550 bp overlap

ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 489 bp overlap

POU5F1 5 datasets

ChIP BG03 GSE21614.POU5F1.BG03 153 bp overlap

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 177 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 553 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 177 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 269 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 578 bp overlap

ChIP TSU-1621MT GSE60477.RARA.TSU-1621MT 278 bp overlap

RBFOX2 4 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 599 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 594 bp overlap

ChIP K562 ENCFF196WTG 594 bp overlap

ChIP K562 ENCFF967GRF 586 bp overlap

RBM22 4 datasets

ChIP K-562 GSE120104.RBM22.K-562 612 bp overlap

ChIP K-562 ENCSR848AOP.RBM22.K-562 604 bp overlap

ChIP K562 ENCFF420JDS 429 bp overlap

ChIP K562 ENCFF629OUL 426 bp overlap

ChIP HCC1599_GSI GSE116871.RBPJ.HCC1599_GSI 293 bp overlap

RELA 2 datasets

ChIP 786-O GSE86092.RELA.786-O 64 bp overlap

ChIP HDF_NUTLIN GSE77225.RELA.HDF_NUTLIN 192 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 635 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 635 bp overlap

RUNX1 3 datasets

ChIP Jurkat GSE85524.RUNX1.Jurkat 465 bp overlap

ChIP ME-1 GSE46044.RUNX1.ME-1 248 bp overlap

ChIP SKNO-1 GSE23730.RUNX1.SKNO-1 401 bp overlap

RUNX1T1 1 dataset

ChIP Kasumi-1_CEBPA-ER_E2 GSE102697.RUNX1T1.Kasumi-1_CEBPA-ER_E2 303 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 292 bp overlap

SMARCA4 1 dataset

ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 187 bp overlap

SPI1 4 datasets

ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 60 bp overlap

ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 77 bp overlap

ChIP THP-1_DIFF GSE25426.SPI1.THP-1_DIFF 141 bp overlap

ChIP U-937 GSE128834.SPI1.U-937 123 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 589 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 572 bp overlap

STAG2 1 dataset

ChIP OCI-AML-3 GSE111537.STAG2.OCI-AML-3 133 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 431 bp overlap

TAF15 2 datasets

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 382 bp overlap

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 369 bp overlap

ChIP ME-1 GSE46044.TAL1.ME-1 442 bp overlap

TCF12 1 dataset

ChIP ME-1 GSE46044.TCF12.ME-1 233 bp overlap

TEAD1 1 dataset

ChIP H69 GSE62274.TEAD1.H69 305 bp overlap

TFDP1 1 dataset

Motif ES_0h ES_0h-TFDP1_MA1122.2 8 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 458 bp overlap

ChIP breast-organoid GSE113909.TP63.breast-organoid 116 bp overlap

TRIM24 2 datasets

ChIP LNCaP-abl_ETOH GSE69331.TRIM24.LNCaP-abl_ETOH 272 bp overlap

ChIP LNCaP_DHT GSE69331.TRIM24.LNCaP_DHT 299 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 509 bp overlap

TRIM28 1 dataset

ChIP HCT-116 GSE72622.TRIM28.HCT-116 318 bp overlap

ChIP K-562 GSE111469.USF2.K-562 195 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 561 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 297 bp overlap

ZBTB33 3 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 635 bp overlap

ChIP K562 ENCFF427SDV 195 bp overlap

ChIP K562 ENCFF875HLX 416 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 467 bp overlap

ZNF148 1 dataset

ChIP K-562 GSE121133.ZNF148.K-562 215 bp overlap

ZNF263 2 datasets

ChIP K-562 ENCSR000EWN.ZNF263.K-562 286 bp overlap

ChIP K562 ENCFF640RNA 68 bp overlap

ZNF281 2 datasets

ChIP K-562 GSE121133.ZNF281.K-562 196 bp overlap

ChIP WTC11 ENCFF551GAV 349 bp overlap

ChIP K-562 ENCSR195QFV.ZNF3.K-562 152 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 156 bp overlap

ZNF512 1 dataset

ChIP WTC11 ENCFF086TTM 207 bp overlap

ZNF524 1 dataset

Motif DE_12h DE_12h-ZNF524_MA2096.1 9 bp overlap

ZNF530 1 dataset

Motif ES_0h ES_0h-ZNF530_MA1981.2 14 bp overlap

ZNF93 1 dataset

Motif DE_12h DE_12h-ZNF93_MA1721.2 14 bp overlap