Predicted to enable protein-N-terminal glutamine amidohydrolase activity. Predicted to be involved in protein modification process. Predicted to be located in cytoplasm. Predicted to be active in cytosol and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Transcription factors with Perturb-seq knockdown data for NTAQ1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = NTAQ1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of NTAQ1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr8:123,156,604–123,157,953 | 259.5 kb | Distal (>10kb) Multiome | 1083 | |
| chr8:123,160,441–123,161,547 | 256.1 kb | Distal (>10kb) Multiome | 590 | |
| chr8:123,205,121–123,205,789 | 211.3 kb | Distal (>10kb) Multiome | 298 | |
| chr8:123,207,081–123,207,716 | 209.4 kb | Distal (>10kb) Multiome | 96 | |
| chr8:123,235,684–123,236,295 | 180.8 kb | Distal (>10kb) Multiome | 110 | |
| chr8:123,240,791–123,241,581 | 175.4 kb | Distal (>10kb) Multiome | 784 | |
| chr8:123,273,286–123,275,625 | 142.0 kb | Distal (>10kb) Multiome | 970 | |
| chr8:123,395,612–123,397,193 | 20.1 kb | Distal (>10kb) Multiome | 1096 | |
| chr8:123,412,789–123,413,692 | 3.1 kb | Proximal (<10kb) | 165 | |
| chr8:123,416,006–123,417,726 | 190 bp | At TSS Multiome | 823 | |
| chr8:123,479,357–123,480,359 | 63.0 kb | Distal (>10kb) Multiome | 179 | |
| chr8:123,539,997–123,542,004 | 124.7 kb | Distal (>10kb) Multiome | 699 | |
| chr8:123,678,684–123,679,495 | 262.5 kb | Distal (>10kb) Multiome | 51 | |
| chr8:123,679,596–123,680,360 | 263.2 kb | Distal (>10kb) Multiome | 85 | |
| chr8:123,767,780–123,769,038 | 351.6 kb | Distal (>10kb) Multiome HiCAR | 744 |
Genomic view of the NTAQ1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.