chr1:167,822,319–167,822,995

chr1 : 167,822,319 – 167,822,995

676 bp 107 TFs 7 linked genes

This 676 bp open chromatin element is linked to 7 target genes and is bound by 107 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000232194		1.9 kb	Proximal	Proximity
ENSG00000250762		2.1 kb	Proximal	Proximity
ADCY10		91.5 kb	Distal	Multiome
MPZL1		100.7 kb	Distal	Multiome
MPC2		113.4 kb	Distal	Multiome
DCAF6		114.0 kb	Distal	Multiome
CREG1		268.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

107 transcription factors

ChIP K-562 ENCSR426URK.AFF1.K-562 202 bp overlap

ARID1A 1 dataset

ChIP endometrial-epithelial-cells GSE106660.ARID1A.endometrial-epithelial-cells 192 bp overlap

ARID5B 1 dataset

ChIP Jurkat GSE97512.ARID5B.Jurkat 224 bp overlap

BACH1 1 dataset

ChIP K562 ENCFF419VIM 55 bp overlap

BRD4 4 datasets

ChIP SUM1315_DMSO GSE63581.BRD4.SUM1315_DMSO 123 bp overlap

ChIP SUM159PT_100nMtrametinib_72h GSE87418.BRD4.SUM159PT_100nMtrametinib_72h 157 bp overlap

ChIP SUM159PT_shMYC_dox_48h GSE87418.BRD4.SUM159PT_shMYC_dox_48h 92 bp overlap

ChIP SW480 GSE110473.BRD4.SW480 242 bp overlap

ChIP MDA-MB-231_JQ1 GSE116879.BRD9.MDA-MB-231_JQ1 300 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 268 bp overlap

ChIP K562 ENCFF673OEZ 411 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.CDK9.MM1-S_JQ1_500NM 167 bp overlap

CEBPB 1 dataset

ChIP HeLa-S3 ENCFF722WEG 85 bp overlap

CLOCK 1 dataset

ChIP U2OS GSE44236.CLOCK.U2OS 112 bp overlap

CREB3 1 dataset

ChIP K-562 ENCSR093FKD.CREB3.K-562 66 bp overlap

CREBBP 1 dataset

ChIP PC-3_GDC-resist GSE147455.CREBBP.PC-3_GDC-resist 119 bp overlap

CTBP1 2 datasets

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 347 bp overlap

ChIP K562 ENCFF403WPG 543 bp overlap

ChIP K-562 ENCSR000EWJ.E2F6.K-562 135 bp overlap

ChIP ProEs GSE59087.EED.ProEs 161 bp overlap

ChIP K-562 ENCSR000BMD.ELF1.K-562 158 bp overlap

ELF3 3 datasets

ChIP PDAC GSE64557.ELF3.PDAC 491 bp overlap

ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 558 bp overlap

ChIP PDAC_SHCTR GSE64557.ELF3.PDAC_SHCTR 520 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 292 bp overlap

ChIP MCF-7_RUNX2_DOX GSE86538.ESR1.MCF-7_RUNX2_DOX 199 bp overlap

ESRRA 4 datasets

ChIP K-562 ENCSR486IFJ.ESRRA.K-562 550 bp overlap

ChIP K562 ENCFF968PEP 389 bp overlap

ChIP SK-BR-3 GSE81651.ESRRA.SK-BR-3 306 bp overlap

ChIP SK-BR-3_EGF GSE81651.ESRRA.SK-BR-3_EGF 235 bp overlap

ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 284 bp overlap

Motif DE_48h DE_48h-ETV1_MA0761.3 9 bp overlap

ETV2::DRGX 1 dataset

Motif DE_48h DE_48h-ETV2DRGX_MA1940.2 12 bp overlap

ETV5::DRGX 1 dataset

Motif DE_48h DE_48h-ETV5DRGX_MA1944.2 12 bp overlap

ETV5::HOXA2 1 dataset

Motif DE_48h DE_48h-ETV5HOXA2_MA1948.2 12 bp overlap

FLI1::DRGX 1 dataset

Motif DE_48h DE_48h-FLI1DRGX_MA1949.2 14 bp overlap

FOXA1 7 datasets

ChIP CFPAC-1 GSE119930.FOXA1.CFPAC-1 407 bp overlap

ChIP CFPAC-1_FOXA1-KO GSE119930.FOXA1.CFPAC-1_FOXA1-KO 333 bp overlap

ChIP CFPAC-1_FOXA2-KO GSE119930.FOXA1.CFPAC-1_FOXA2-KO 456 bp overlap

ChIP NCI-H3122 GSE39998.FOXA1.NCI-H3122 195 bp overlap

ChIP PDAC GSE64557.FOXA1.PDAC 447 bp overlap

ChIP PDAC_KOKLF5 GSE64557.FOXA1.PDAC_KOKLF5 420 bp overlap

ChIP PDAC_SHCTR GSE64557.FOXA1.PDAC_SHCTR 456 bp overlap

FOXA2 8 datasets

ChIP CFPAC-1 GSE119930.FOXA2.CFPAC-1 416 bp overlap

ChIP CFPAC-1_EV GSE119930.FOXA2.CFPAC-1_EV 492 bp overlap

ChIP CFPAC-1_HNF1B-KO GSE119930.FOXA2.CFPAC-1_HNF1B-KO 301 bp overlap

ChIP CFPAC-1_HOXB8-OE GSE119930.FOXA2.CFPAC-1_HOXB8-OE 334 bp overlap

ChIP Caco-2 GSE66218.FOXA2.Caco-2 134 bp overlap

ChIP DE DE-FOXA2-1 631 bp overlap

ChIP DE DE-FOXA2-2 571 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 199 bp overlap

FOXA3 1 dataset

ChIP K562 ENCFF781VSC 341 bp overlap

FOXK2 1 dataset

ChIP K562 ENCFF245WKP 289 bp overlap

GATA1::TAL1 1 dataset

Motif DE_48h DE_48h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 1 dataset

ChIP SKH1 GSE87283.GATA2.SKH1 284 bp overlap

GATA3 1 dataset

ChIP Jurkat GSE76181.GATA3.Jurkat 190 bp overlap

GATA4 3 datasets

ChIP DE DE-GATA4-1 523 bp overlap

ChIP DE DE-GATA4-2 562 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 257 bp overlap

GATA6 9 datasets

ChIP DE DE-GATA6-1 495 bp overlap

ChIP DE DE-GATA6-2 585 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 431 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 268 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 259 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 391 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 310 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 527 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 303 bp overlap

HDAC1 2 datasets

ChIP K-562 ENCSR387UWP.HDAC1.K-562 399 bp overlap

ChIP K562 ENCFF968WBH 390 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR893WSB.HDAC2.K-562 259 bp overlap

HDAC8 1 dataset

ChIP K-562 ENCSR000DJZ.HDAC8.K-562 165 bp overlap

ChIP K-562 ENCSR197ALX.HDGF.K-562 237 bp overlap

HINFP 1 dataset

ChIP K562 ENCFF361QXJ 297 bp overlap

HMBOX1 5 datasets

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 453 bp overlap

ChIP K562 ENCFF055GAZ 329 bp overlap

ChIP K562 ENCFF055GAZ 531 bp overlap

ChIP K562 ENCFF317JJX 313 bp overlap

ChIP K562 ENCFF317JJX 513 bp overlap

HMGXB4 1 dataset

ChIP K562 ENCFF620JLK 83 bp overlap

HOXB2::ELK1 1 dataset

Motif DE_48h DE_48h-HOXB2ELK1_MA1957.1 14 bp overlap

HOXC13 1 dataset

Motif DE_48h DE_48h-HOXC13_MA0907.2 9 bp overlap

IKZF1 1 dataset

ChIP K562 ENCFF348IBL 175 bp overlap

ChIP PDAC GSE64557.IRF1.PDAC 229 bp overlap

Motif DE_48h DE_48h-ISL2_MA0914.2 6 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 279 bp overlap

L3MBTL2 3 datasets

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 411 bp overlap

ChIP K562 ENCFF320EQC 479 bp overlap

ChIP K562 ENCFF320EQC 599 bp overlap

ChIP Kasumi-1_SICTR GSE60130.LMO2.Kasumi-1_SICTR 149 bp overlap

ChIP HeLa-S3 ENCFF019SXC 110 bp overlap

ChIP HeLa-S3 ENCSR000EZF.MAX.HeLa-S3 325 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 151 bp overlap

ChIP K562 ENCFF110LJS 351 bp overlap

ChIP K562 ENCFF524IJO 358 bp overlap

MECOM 1 dataset

ChIP K562 ENCFF773RGL 311 bp overlap

MED1 4 datasets

ChIP hMSC-TERT4_4h GSE104537.MED1.hMSC-TERT4_4h 62 bp overlap

ChIP hMSC-TERT4_osteoblast-4H GSE113253.MED1.hMSC-TERT4_osteoblast-4H 143 bp overlap

ChIP hMSC-TERT4_osteoblast-D3 GSE113253.MED1.hMSC-TERT4_osteoblast-D3 118 bp overlap

ChIP hMSC-TERT4_osteoblast-D7 GSE113253.MED1.hMSC-TERT4_osteoblast-D7 126 bp overlap

MEIS1 1 dataset

Motif DE_48h DE_48h-MEIS1_MA0498.3 5 bp overlap

ChIP K-562 ENCSR710WLO.MGA.K-562 237 bp overlap

MGA::EVX1 1 dataset

Motif DE_48h DE_48h-MGAEVX1_MA1960.2 11 bp overlap

MITF 2 datasets

ChIP K-562 ENCSR797SWM.MITF.K-562 213 bp overlap

ChIP K562 ENCFF731XJJ 347 bp overlap

ChIP K-562 ENCSR807BGP.MTA1.K-562 227 bp overlap

MTA3 2 datasets

ChIP K-562 ENCSR180NCY.MTA3.K-562 376 bp overlap

ChIP K-562 ENCSR914NEI.MTA3.K-562 266 bp overlap

ChIP DU528 GSE94000.MYB.DU528 517 bp overlap

ChIP Loucy GSE94000.MYB.Loucy 237 bp overlap

MYBL2 1 dataset

Motif DE_48h DE_48h-MYBL2_MA0777.1 15 bp overlap

ChIP Jurkat GSE83777.MYC.Jurkat 287 bp overlap

ChIP K-562 ENCSR085QEV.NBN.K-562 218 bp overlap

NCAPH2 1 dataset

ChIP RMG-I_ARID1A-KO GSE120058.NCAPH2.RMG-I_ARID1A-KO 382 bp overlap

ChIP K562 ENCFF047YKA 126 bp overlap

NFE2L2 1 dataset

ChIP BEAS-2B_arsenic GSE145834.NFE2L2.BEAS-2B_arsenic 274 bp overlap

NKX2-1 1 dataset

ChIP NCI-H3122 GSE39998.NKX2-1.NCI-H3122 205 bp overlap

NR2C1 2 datasets

ChIP K-562 ENCSR178DEG.NR2C1.K-562 191 bp overlap

ChIP K562 ENCFF568JLK 411 bp overlap

NR2F1 2 datasets

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 443 bp overlap

ChIP K562 ENCFF221HJH 493 bp overlap

NR2F2 2 datasets

ChIP K-562 ENCSR000BRS.NR2F2.K-562 340 bp overlap

ChIP K562 ENCFF004YPK 391 bp overlap

ChIP HeLa-S3 GSE108856.NRF1.HeLa-S3 304 bp overlap

Nkx3-2 1 dataset

Motif DE_48h DE_48h-Nkx3-2_MA0122.4 10 bp overlap

Nr2e1 1 dataset

Motif DE_48h DE_48h-Nr2e1_MA0676.1 9 bp overlap

ONECUT1 1 dataset

Motif DE_48h DE_48h-ONECUT1_MA0679.3 9 bp overlap

ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 232 bp overlap

PKNOX1 1 dataset

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 294 bp overlap

POLR2A 1 dataset

ChIP stomach ENCFF820WZN 345 bp overlap

Motif DE_48h DE_48h-Pgr_MA2323.1 17 bp overlap

RUNX1 3 datasets

ChIP K562 ENCFF738EUI 277 bp overlap

ChIP SKH1 GSE87283.RUNX1.SKH1 251 bp overlap

ChIP SKH1_10d GSE87283.RUNX1.SKH1_10d 194 bp overlap

RUNX2 1 dataset

ChIP Karpas-45 GSE151819.RUNX2.Karpas-45 178 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 133 bp overlap

SMAD2-3 4 datasets

ChIP HGrC1_WT GSE138496.SMAD2-3.HGrC1_WT 135 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 617 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 302 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 518 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 496 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 676 bp overlap

SMAD4 2 datasets

ChIP K562 ENCFF628RBP 296 bp overlap

ChIP K562 ENCFF628RBP 498 bp overlap

SMARCA4 4 datasets

ChIP A-549_AG15686 GSE132290.SMARCA4.A-549_AG15686 322 bp overlap

ChIP A-549_AG15689 GSE132290.SMARCA4.A-549_AG15689 300 bp overlap

ChIP CTV-1_DSG GSE128835.SMARCA4.CTV-1_DSG 254 bp overlap

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 382 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 316 bp overlap

SNAI2 1 dataset

ChIP PC-9_2DF GSE131687.SNAI2.PC-9_2DF 195 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 351 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 460 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 346 bp overlap

ChIP K562 ENCFF059YCJ 385 bp overlap

SPDEF 1 dataset

Motif DE_48h DE_48h-SPDEF_MA0686.2 10 bp overlap

ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 214 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 199 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 199 bp overlap

TBX19 1 dataset

Motif DE_48h DE_48h-TBX19_MA0804.2 17 bp overlap

Motif DE_48h DE_48h-TBXT_MA0009.2 16 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 232 bp overlap

TEAD4 1 dataset

ChIP K562 ENCFF673NIK 327 bp overlap

ChIP K562 ENCFF202SFC 236 bp overlap

YY1AP1 2 datasets

ChIP PC-9_1DF GSE131687.YY1AP1.PC-9_1DF 333 bp overlap

ChIP PC-9_2DF_DMSO GSE131687.YY1AP1.PC-9_2DF_DMSO 132 bp overlap

ZBTB40 1 dataset

ChIP K-562 ENCSR237VLT.ZBTB40.K-562 162 bp overlap

ZBTB7A 1 dataset

ChIP K-562 GSE103445.ZBTB7A.K-562 80 bp overlap

ZEB2 2 datasets

ChIP K-562 ENCSR322CFO.ZEB2.K-562 320 bp overlap

ChIP K-562 ENCSR004GKA.ZEB2.K-562 475 bp overlap

ChIP HeLa-S3 ENCSR855WKQ.ZHX1.HeLa-S3 116 bp overlap

ZNF143 2 datasets

ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 156 bp overlap

ChIP FLP76_T4 GSE39263.ZNF143.FLP76_T4 153 bp overlap

ZNF592 2 datasets

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 248 bp overlap

ChIP K562 ENCFF547OSS 451 bp overlap

ZNF652 1 dataset

Motif DE_48h DE_48h-ZNF652_MA1657.2 9 bp overlap