chr6 : 27,049,960 – 27,050,724
764 bp 99 TFs 5 linked genes
This 764 bp open chromatin element is linked to 5 target genes and is bound by 99 transcription factors.
Linked Genes
5 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
LINC00240 30.0 kb Distal Multiome
LARRPM 30.0 kb Distal Multiome
GUSBP2 93.7 kb Distal Multiome
H2AC12 96.8 kb Distal Multiome
ENSG00000290009 128.1 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:27,044,960 – 27,055,724
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
99 transcription factors
Source
Cell type
AGO1 1 dataset
ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 287 bp overlap
AR 7 datasets
ChIP LNCaP_SHFOXP1_DHT GSE62492.AR.LNCaP_SHFOXP1_DHT 109 bp overlap
ChIP MCF-7 ERP001226.AR.MCF-7 130 bp overlap
ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 147 bp overlap
ChIP prostate-cancer_PDX_35 GSE130408.AR.prostate-cancer_PDX_35 225 bp overlap
ChIP prostate-cancer_PDX_58 GSE130408.AR.prostate-cancer_PDX_58 67 bp overlap
ChIP prostate-cancer_PDX_78 GSE130408.AR.prostate-cancer_PDX_78 121 bp overlap
ChIP prostate_1798_T GSE130408.AR.prostate_1798_T 282 bp overlap
ARID1A 2 datasets
ChIP MCF-7_4-hydroxytamoxifen GSE123284.ARID1A.MCF-7_4-hydroxytamoxifen 602 bp overlap
ChIP MCF-7_Fulvestrant GSE123284.ARID1A.MCF-7_Fulvestrant 382 bp overlap
ARRB1 1 dataset
ChIP prostate GSE55615.ARRB1.prostate 135 bp overlap
ASCL1 1 dataset
ChIP NCI-H82 GSE69394.ASCL1.NCI-H82 101 bp overlap
Ahr::Arnt 1 dataset
Motif DE_48h DE_48h-AhrArnt_MA0006.2 5 bp overlap
BRD4 2 datasets
ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 329 bp overlap
ChIP hESC GSE33281.BRD4.hESC 90 bp overlap
CDK6 1 dataset
ChIP KB GSE52469.CDK6.KB 110 bp overlap
CREBBP 1 dataset
ChIP MCF-7 ERP000901.CREBBP.MCF-7 132 bp overlap
CRX 3 datasets
ChIP retina_Hu20 GSE137311.CRX.retina_Hu20 327 bp overlap
ChIP retina_Hu3 GSE137311.CRX.retina_Hu3 311 bp overlap
ChIP retina_Hu6 GSE137311.CRX.retina_Hu6 522 bp overlap
CTCF 10 datasets
ChIP H1 ENCFF764RHO 215 bp overlap
ChIP H9 ENCFF152GTF 231 bp overlap
ChIP T-47D_NaCl-triptolide GSE111923.CTCF.T-47D_NaCl-triptolide 272 bp overlap
ChIP endodermal cell ENCFF471YCZ 132 bp overlap
ChIP hiPSC_IB12 GSE106870.CTCF.hiPSC_IB12 129 bp overlap
ChIP neural progenitor cell ENCFF420RBO 256 bp overlap
ChIP neural_progenitor ENCSR125NBL.CTCF.neural_progenitor 142 bp overlap
ChIP prostate gland ENCFF979KAF 381 bp overlap
ChIP retina_Hu25 GSE137311.CTCF.retina_Hu25 185 bp overlap
ChIP retina_Hu6 GSE137311.CTCF.retina_Hu6 271 bp overlap
CTCFL 1 dataset
ChIP K-562 ENCSR000BNK.CTCFL.K-562 84 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF262VBH 385 bp overlap
E2F6 2 datasets
ChIP H1 ENCFF785DWK 451 bp overlap
ChIP WA01 ENCSR000BSI.E2F6.WA01 273 bp overlap
ESR1 22 datasets
ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 256 bp overlap
ChIP MCF-7 GSE48930.ESR1.MCF-7 206 bp overlap
ChIP MCF-7 GSE41561.ESR1.MCF-7 130 bp overlap
ChIP MCF-7_E2 ERP000209.ESR1.MCF-7_E2 155 bp overlap
ChIP MCF-7_E2 GSE14664.ESR1.MCF-7_E2 116 bp overlap
ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 269 bp overlap
ChIP MCF-7_ICI GSE125594.ESR1.MCF-7_ICI 256 bp overlap
ChIP MCF-7_IL1b_45m GSE67295.ESR1.MCF-7_IL1b_45m 218 bp overlap
ChIP MCF-7_LY2_ETOH GSE54592.ESR1.MCF-7_LY2_ETOH 173 bp overlap
ChIP MCF-7_R5020 GSE68355.ESR1.MCF-7_R5020 215 bp overlap
ChIP MCF-7_SHCTR_E2_TNF GSE59530.ESR1.MCF-7_SHCTR_E2_TNF 208 bp overlap
ChIP MCF-7_SIGATA_E2 GSE40129.ESR1.MCF-7_SIGATA_E2 217 bp overlap
ChIP MCF-7_TNFa_45m GSE67295.ESR1.MCF-7_TNFa_45m 202 bp overlap
ChIP MCF-7_Veh GSE67295.ESR1.MCF-7_Veh 172 bp overlap
ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 488 bp overlap
ChIP MCF-7_jc5850 GSE126004.ESR1.MCF-7_jc5850 219 bp overlap
ChIP MCF-7_parental GSE123284.ESR1.MCF-7_parental 193 bp overlap
ChIP T-47D GSE148277.ESR1.T-47D 296 bp overlap
ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 318 bp overlap
ChIP T-47D_Y537S GSE148277.ESR1.T-47D_Y537S 388 bp overlap
ChIP T-47D_Y537S_E2 GSE148277.ESR1.T-47D_Y537S_E2 364 bp overlap
ChIP breast_tumor_Male_14 GSE104399.ESR1.breast_tumor_Male_14 177 bp overlap
ETV5::FOXO1 1 dataset
Motif DE_48h DE_48h-ETV5FOXO1_MA1947.2 10 bp overlap
EZH2 2 datasets
ChIP neural progenitor cell ENCFF018MKA 517 bp overlap
ChIP neural progenitor cell ENCFF018MKA 314 bp overlap
EZH2_phosphoT487 1 dataset
ChIP neural_progenitor ENCSR656MXA.EZH2_phosphoT487.neural_progenitor 225 bp overlap
FOXA1 6 datasets
ChIP MCF-7_E2 GSE60270.FOXA1.MCF-7_E2 253 bp overlap
ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 390 bp overlap
ChIP primary-prostate-cancer_P2_DSG GSE114737.FOXA1.primary-prostate-cancer_P2_DSG 301 bp overlap
ChIP prostate-cancer_PDX_136 GSE130408.FOXA1.prostate-cancer_PDX_136 75 bp overlap
ChIP prostate_2078 GSE130408.FOXA1.prostate_2078 181 bp overlap
ChIP prostate_2480 GSE130408.FOXA1.prostate_2480 228 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 417 bp overlap
ChIP DE DE-FOXA2-2 329 bp overlap
GATA2 1 dataset
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 420 bp overlap
GATA4 3 datasets
ChIP DE DE-GATA4-1 250 bp overlap
ChIP DE DE-GATA4-1 271 bp overlap
ChIP DE DE-GATA4-2 444 bp overlap
GATA6 6 datasets
ChIP DE DE-GATA6-1 243 bp overlap
ChIP DE DE-GATA6-2 550 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 128 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 238 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 139 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 244 bp overlap
GRHL2 5 datasets
ChIP HBE GSE46194.GRHL2.HBE 227 bp overlap
ChIP MCF-7 GSE109820.GRHL2.MCF-7 283 bp overlap
ChIP MCF-7 GSE99680.GRHL2.MCF-7 216 bp overlap
ChIP MCF-7_E2_45min GSE109820.GRHL2.MCF-7_E2_45min 346 bp overlap
ChIP T-47D GSE99680.GRHL2.T-47D 296 bp overlap
GSPT2 1 dataset
ChIP HEK293T GSE35197.GSPT2.HEK293T 197 bp overlap
HDAC1 1 dataset
ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.HDAC1.MCF-7_parental_4-hydroxytamoxifen 239 bp overlap
HEXIM1 1 dataset
ChIP HCT-116 GSE72622.HEXIM1.HCT-116 245 bp overlap
HOXB13 2 datasets
Motif DE_48h DE_48h-HOXB13_MA0901.3 9 bp overlap
ChIP prostate_2483_T GSE130408.HOXB13.prostate_2483_T 235 bp overlap
Hoxa13 1 dataset
Motif DE_48h DE_48h-Hoxa13_MA0650.4 8 bp overlap
KDM4C 1 dataset
ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 173 bp overlap
KDM5B 1 dataset
ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 154 bp overlap
KLF1 1 dataset
Motif DE_48h DE_48h-KLF1_MA0493.3 8 bp overlap
KLF10 1 dataset
Motif DE_48h DE_48h-KLF10_MA1511.2 9 bp overlap
KLF11 1 dataset
Motif DE_48h DE_48h-KLF11_MA1512.2 10 bp overlap
KLF12 1 dataset
Motif DE_48h DE_48h-KLF12_MA0742.2 9 bp overlap
KLF13 1 dataset
Motif DE_48h DE_48h-KLF13_MA0657.2 17 bp overlap
KLF14 1 dataset
Motif DE_48h DE_48h-KLF14_MA0740.2 9 bp overlap
KLF16 1 dataset
Motif DE_48h DE_48h-KLF16_MA0741.1 11 bp overlap
KLF2 1 dataset
Motif DE_48h DE_48h-KLF2_MA1515.2 8 bp overlap
KLF3 1 dataset
Motif DE_48h DE_48h-KLF3_MA1516.2 10 bp overlap
KLF5 1 dataset
Motif DE_48h DE_48h-KLF5_MA0599.1 10 bp overlap
KLF6 1 dataset
Motif DE_48h DE_48h-KLF6_MA1517.2 9 bp overlap
KLF7 1 dataset
Motif DE_48h DE_48h-KLF7_MA1959.2 8 bp overlap
KLF9 1 dataset
Motif DE_48h DE_48h-KLF9_MA1107.3 11 bp overlap
LMO2 1 dataset
ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 157 bp overlap
MAX 6 datasets
ChIP H1 ENCFF914VQY 357 bp overlap
ChIP Hep-G2 ENCSR000BTM.MAX.Hep-G2 156 bp overlap
ChIP MCF-7 ENCFF169IXS 437 bp overlap
ChIP MCF-7 ENCSR000BUL.MAX.MCF-7 192 bp overlap
ChIP NCI-H128 GSE41105.MAX.NCI-H128 277 bp overlap
ChIP WTC11 ENCFF223QFY 535 bp overlap
MED1 2 datasets
ChIP MCF-7_SHCTR GSE60270.MED1.MCF-7_SHCTR 215 bp overlap
ChIP MCF-7_SHRARS_E2 GSE60270.MED1.MCF-7_SHRARS_E2 257 bp overlap
MEF2D 1 dataset
ChIP retina_Hu25 GSE137311.MEF2D.retina_Hu25 320 bp overlap
MNT 2 datasets
ChIP MCF-7 ENCFF144ZFZ 445 bp overlap
ChIP MCF-7 ENCSR663ZZZ.MNT.MCF-7 266 bp overlap
MNX1 2 datasets
ChIP Hep-G2 ENCSR108MKR.MNX1.Hep-G2 256 bp overlap
ChIP HepG2 ENCFF938KYA 567 bp overlap
MYC 2 datasets
ChIP MCF-7 ENCFF542NWJ 305 bp overlap
ChIP MCF-7 ENCSR000DMQ.MYC.MCF-7 127 bp overlap
NRIP1 1 dataset
ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 184 bp overlap
NUTM1 1 dataset
ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 623 bp overlap
OTX2 1 dataset
ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 365 bp overlap
PCBP1 1 dataset
ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 171 bp overlap
PHF19 1 dataset
ChIP DU145_SH4 GSE135623.PHF19.DU145_SH4 264 bp overlap
POGZ 1 dataset
ChIP HepG2 ENCFF153UUK 517 bp overlap
POLR2A 2 datasets
ChIP prostate gland ENCFF881OMH 325 bp overlap
ChIP upper lobe of left lung ENCFF199JUI 405 bp overlap
POU2F1 2 datasets
ChIP T-47D GSE148277.POU2F1.T-47D 245 bp overlap
ChIP T-47D_D538G GSE148277.POU2F1.T-47D_D538G 253 bp overlap
POU5F1 1 dataset
ChIP BG03 GSE21614.POU5F1.BG03 301 bp overlap
PRKDC 1 dataset
ChIP MCF-7_E2 GSE60270.PRKDC.MCF-7_E2 159 bp overlap
RAD21 1 dataset
ChIP MCF-7_E2_SHCTCF ERP000209.RAD21.MCF-7_E2_SHCTCF 106 bp overlap
RBPJ 1 dataset
Motif DE_48h DE_48h-RBPJ_MA1116.2 6 bp overlap
RELA 3 datasets
ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 579 bp overlap
ChIP MCF-7_IL1b_45m GSE67295.RELA.MCF-7_IL1b_45m 148 bp overlap
ChIP MCF-7_Veh GSE67295.RELA.MCF-7_Veh 166 bp overlap
RORB 1 dataset
ChIP retina_Hu22 GSE137311.RORB.retina_Hu22 480 bp overlap
RUNX1 1 dataset
ChIP AML_age-50-70 GSE111821.RUNX1.AML_age-50-70 300 bp overlap
SIN3A 2 datasets
ChIP WA01 ENCSR000EBO.SIN3A.WA01 120 bp overlap
ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 202 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 683 bp overlap
SMAD2_3 2 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 183 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 281 bp overlap
SMARCA4 2 datasets
ChIP MCF-7 GSE123284.SMARCA4.MCF-7 285 bp overlap
ChIP MCF-7_parental GSE123284.SMARCA4.MCF-7_parental 195 bp overlap
SMARCB1 5 datasets
ChIP MCF-7 GSE123284.SMARCB1.MCF-7 348 bp overlap
ChIP MCF-7_4-hydroxytamoxifen GSE123284.SMARCB1.MCF-7_4-hydroxytamoxifen 457 bp overlap
ChIP MCF-7_DCDT GSE123284.SMARCB1.MCF-7_DCDT 295 bp overlap
ChIP MCF-7_JQ1 GSE123284.SMARCB1.MCF-7_JQ1 304 bp overlap
ChIP MCF-7_estrogen GSE123284.SMARCB1.MCF-7_estrogen 325 bp overlap
SMARCC1 1 dataset
ChIP MCF-7 GSE124225.SMARCC1.MCF-7 266 bp overlap
SMC1A 1 dataset
ChIP MCF-7_EtOH GSE115602.SMC1A.MCF-7_EtOH 215 bp overlap
SOX2 1 dataset
ChIP RENVM GSE49404.SOX2.RENVM 144 bp overlap
SP3 1 dataset
Motif DE_48h DE_48h-SP3_MA0746.3 11 bp overlap
SP4 1 dataset
Motif DE_48h DE_48h-SP4_MA0685.2 9 bp overlap
SP8 1 dataset
Motif DE_48h DE_48h-SP8_MA0747.2 11 bp overlap
SP9 1 dataset
Motif DE_48h DE_48h-SP9_MA1564.2 10 bp overlap
SPI1 1 dataset
ChIP macrophage_IFNG GSE47188.SPI1.macrophage_IFNG 211 bp overlap
STAG1 2 datasets
ChIP MCF-7_E2 ERP000209.STAG1.MCF-7_E2 127 bp overlap
ChIP MCF-7_E2_SHCTCF ERP000209.STAG1.MCF-7_E2_SHCTCF 123 bp overlap
STAT3 4 datasets
ChIP BT-474 GSE152203.STAT3.BT-474 190 bp overlap
ChIP MCF-7_jc5836 GSE126004.STAT3.MCF-7_jc5836 302 bp overlap
ChIP MCF-7_jc5838 GSE126004.STAT3.MCF-7_jc5838 346 bp overlap
ChIP MDA-MB-361 GSE152203.STAT3.MDA-MB-361 229 bp overlap
Stat5b 1 dataset
Motif DE_48h DE_48h-Stat5b_MA1625.2 9 bp overlap
TBP 7 datasets
Motif DE_48h DE_48h-TBP_MA0108.3 7 bp overlap
ChIP K-562 GSE55306.TBP.K-562 192 bp overlap
ChIP hESC GSE122298.TBP.hESC 334 bp overlap
ChIP hESC_10h GSE122298.TBP.hESC_10h 110 bp overlap
ChIP hESC_2h GSE122298.TBP.hESC_2h 167 bp overlap
ChIP hESC_2h GSE122298.TBP.hESC_2h 172 bp overlap
ChIP hESC_8h GSE122298.TBP.hESC_8h 232 bp overlap
TEAD4 1 dataset
ChIP hMSC-TERT4 GSE140782.TEAD4.hMSC-TERT4 224 bp overlap
TFAP2A 1 dataset
ChIP MCF-7_E2 GSE60270.TFAP2A.MCF-7_E2 205 bp overlap
TFAP2C 2 datasets
ChIP MCF-7_E2 GSE23852.TFAP2C.MCF-7_E2 167 bp overlap
ChIP MCF-7_ETOH GSE23852.TFAP2C.MCF-7_ETOH 267 bp overlap
TP63 7 datasets
ChIP BxPC-3 GSE115461.TP63.BxPC-3 312 bp overlap
ChIP keratinocyte GSE33571.TP63.keratinocyte 157 bp overlap
ChIP keratinocyte_D0 GSE59824.TP63.keratinocyte_D0 231 bp overlap
ChIP keratinocyte_D2 GSE59824.TP63.keratinocyte_D2 220 bp overlap
ChIP keratinocyte_D7 GSE59824.TP63.keratinocyte_D7 190 bp overlap
ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 199 bp overlap
ChIP keratinocyte_epidermal GSE67382.TP63.keratinocyte_epidermal 150 bp overlap
ZBED4 1 dataset
Motif DE_48h DE_48h-ZBED4_MA2328.1 10 bp overlap
ZBTB48 1 dataset
ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 377 bp overlap
ZBTB7A 1 dataset
ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 216 bp overlap
ZNF143 1 dataset
ChIP MCF-7_E2 GSE76454.ZNF143.MCF-7_E2 158 bp overlap
ZNF530 1 dataset
Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap
ZNF667 1 dataset
Motif DE_48h DE_48h-ZNF667_MA1984.2 11 bp overlap
ZNF682 1 dataset
Motif DE_48h DE_48h-ZNF682_MA1599.2 11 bp overlap
ZNF687 1 dataset
ChIP HepG2 ENCFF653WIX 680 bp overlap
ZNF708 1 dataset
Motif DE_48h DE_48h-ZNF708_MA1730.2 9 bp overlap
ZNF737 1 dataset
ChIP Hep-G2 ENCSR127IHN.ZNF737.Hep-G2 162 bp overlap
ZNF891 1 dataset
ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 194 bp overlap
Znf423 1 dataset
Motif DE_48h DE_48h-Znf423_MA0116.1 15 bp overlap
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