chr4 : 38,489,064 – 38,489,939
875 bp 119 TFs 1 linked gene
This 875 bp open chromatin element is linked to KLF3 and is bound by 119 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
KLF3 174.7 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:38,484,064 – 38,494,939
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
119 transcription factors
Source
Cell type
ARNTL 1 dataset
ChIP U2OS_trough_DMOG GSE85096.ARNTL.U2OS_trough_DMOG 229 bp overlap
ASH2L 2 datasets
ChIP H1 ENCFF399KAM 458 bp overlap
ChIP WA01 ENCSR850KIP.ASH2L.WA01 800 bp overlap
BCOR 1 dataset
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 161 bp overlap
BHLHE22 1 dataset
Motif ES_0h ES_0h-BHLHE22_MA1635.2 6 bp overlap
BRD2 1 dataset
ChIP SK-MEL-147 GSE94488.BRD2.SK-MEL-147 480 bp overlap
BRD4 10 datasets
ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 354 bp overlap
ChIP HUVEC-C GSE60171.BRD4.HUVEC-C 208 bp overlap
ChIP K-562_iBET-BD2 GSE138084.BRD4.K-562_iBET-BD2 321 bp overlap
ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 568 bp overlap
ChIP cortical-interneuron_KCl-pos GSE117508.BRD4.cortical-interneuron_KCl-pos 166 bp overlap
ChIP hESC GSE33281.BRD4.hESC 205 bp overlap
ChIP retina_AB1-FW13 GSE86981.BRD4.retina_AB1-FW13 599 bp overlap
ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 674 bp overlap
ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 442 bp overlap
ChIP retina_AB1-FW23 GSE86981.BRD4.retina_AB1-FW23 455 bp overlap
CASZ1 1 dataset
ChIP rhabdomyosarcoma_DOX GSE126142.CASZ1.rhabdomyosarcoma_DOX 192 bp overlap
CEBPB 1 dataset
ChIP monocyte GSE98367.CEBPB.monocyte 154 bp overlap
CHD2 2 datasets
ChIP H1 ENCFF991MKH 331 bp overlap
ChIP WA01 ENCSR000EBT.CHD2.WA01 131 bp overlap
CHD7 2 datasets
ChIP hiPSC_AF22_abD3F5 GSE108506.CHD7.hiPSC_AF22_abD3F5 286 bp overlap
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 875 bp overlap
CREB1 1 dataset
ChIP WA01 ENCSR000BSN.CREB1.WA01 143 bp overlap
CREBBP 1 dataset
ChIP PC-3 GSE147455.CREBBP.PC-3 187 bp overlap
CTBP1 1 dataset
ChIP K-562 ENCSR201NQZ.CTBP1.K-562 259 bp overlap
CTCF 5 datasets
ChIP islet ERP004003.CTCF.islet 335 bp overlap
ChIP neural progenitor cell ENCFF420RBO 147 bp overlap
ChIP neural_progenitor ENCSR125NBL.CTCF.neural_progenitor 325 bp overlap
ChIP parathyroid adenoma ENCFF173NJK 421 bp overlap
ChIP tibial-nerve ENCSR875NEW.CTCF.tibial-nerve 311 bp overlap
E2F6 3 datasets
Motif ES_0h ES_0h-E2F6_MA0471.3 8 bp overlap
ChIP H1 ENCFF785DWK 451 bp overlap
ChIP WA01 ENCSR000BSI.E2F6.WA01 114 bp overlap
ELF4 1 dataset
ChIP HepG2 ENCFF752OAT 587 bp overlap
ESR1 1 dataset
ChIP breast_tumor_Male_10 GSE104399.ESR1.breast_tumor_Male_10 223 bp overlap
EWSR1-FLI1 2 datasets
Motif ES_0h ES_0h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif ES_0h ES_0h-EWSR1-FLI1_MA0149.1 18 bp overlap
EZH2 1 dataset
ChIP neural progenitor cell ENCFF018MKA 557 bp overlap
FEZF2 1 dataset
Motif ES_0h ES_0h-FEZF2_MA2341.1 8 bp overlap
FOXA2 1 dataset
ChIP DE DE-FOXA2-1 221 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 423 bp overlap
ChIP DE DE-GATA4-2 478 bp overlap
GATA6 2 datasets
ChIP DE DE-GATA6-1 282 bp overlap
ChIP DE DE-GATA6-2 498 bp overlap
GLIS3 1 dataset
ChIP H9_plus GSE109562.GLIS3.H9_plus 292 bp overlap
HDAC1 2 datasets
ChIP K-562 ENCSR711VWL.HDAC1.K-562 231 bp overlap
ChIP K562 ENCFF928TKZ 457 bp overlap
HDAC2 1 dataset
ChIP WA01 ENCSR000AVB.HDAC2.WA01 139 bp overlap
HLF 1 dataset
ChIP HepG2 ENCFF854JLR 75 bp overlap
IKZF1 1 dataset
ChIP K-562 ENCSR395HWC.IKZF1.K-562 174 bp overlap
INSM1 1 dataset
Motif ES_0h ES_0h-INSM1_MA0155.1 12 bp overlap
JUND 2 datasets
ChIP H1 ENCFF010YXS 311 bp overlap
ChIP WA01 ENCSR000EBZ.JUND.WA01 293 bp overlap
KDM1A 1 dataset
ChIP K562 ENCFF133OLU 461 bp overlap
KDM4A 1 dataset
ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 170 bp overlap
KDM5B 2 datasets
ChIP HCC2157 GSE46055.KDM5B.HCC2157 125 bp overlap
ChIP SUM185 GSE46055.KDM5B.SUM185 126 bp overlap
KLF1 1 dataset
Motif ES_0h ES_0h-KLF1_MA0493.3 8 bp overlap
KLF15 1 dataset
Motif ES_0h ES_0h-KLF15_MA1513.2 8 bp overlap
KLF2 1 dataset
Motif ES_0h ES_0h-KLF2_MA1515.2 8 bp overlap
KLF4 4 datasets
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 250 bp overlap
Motif ES_0h ES_0h-KLF4_MA0039.5 8 bp overlap
Motif ES_0h ES_0h-KLF4_MA0039.5 8 bp overlap
ChIP HAP1 GSE130417.KLF4.HAP1 158 bp overlap
KLF5 2 datasets
Motif ES_0h ES_0h-KLF5_MA0599.1 10 bp overlap
Motif ES_0h ES_0h-KLF5_MA0599.1 10 bp overlap
LHX6 1 dataset
Motif ES_0h ES_0h-LHX6_MA0658.2 8 bp overlap
MAF1 1 dataset
ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 163 bp overlap
MED1 1 dataset
ChIP VCaP_R1881 GSE148358.MED1.VCaP_R1881 243 bp overlap
MTA2 1 dataset
ChIP K-562 ENCSR411UYA.MTA2.K-562 247 bp overlap
NANOG 3 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 824 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 105 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 210 bp overlap
NEUROD1 1 dataset
ChIP K-562 ENCSR986CDX.NEUROD1.K-562 143 bp overlap
NFATC3 1 dataset
ChIP Hep-G2 GSE97661.NFATC3.Hep-G2 255 bp overlap
NFE2L1 1 dataset
ChIP WTC11 ENCFF644BPU 377 bp overlap
NKX3-1 1 dataset
ChIP islet ERP004003.NKX3-1.islet 297 bp overlap
NR1D1 1 dataset
Motif ES_0h ES_0h-NR1D1_MA1531.2 14 bp overlap
NR1D2 1 dataset
Motif ES_0h ES_0h-NR1D2_MA1532.2 15 bp overlap
NR1H2 1 dataset
ChIP HT29_GW3965_48H GSE77039.NR1H2.HT29_GW3965_48H 151 bp overlap
NR1H2::RXRA 1 dataset
Motif ES_0h ES_0h-NR1H2RXRA_MA0115.1 17 bp overlap
NR2C2 1 dataset
Motif ES_0h ES_0h-NR2C2_MA0504.2 14 bp overlap
Neurod2 1 dataset
Motif ES_0h ES_0h-Neurod2_MA1993.2 6 bp overlap
OTX2 1 dataset
ChIP retina_Hu7 GSE137311.OTX2.retina_Hu7 203 bp overlap
Olig2 1 dataset
Motif ES_0h ES_0h-Olig2_MA1997.2 6 bp overlap
PAX3-FOXO1 1 dataset
ChIP Hs-352-Sk_PAX3-FOXO1-vector GSE83725.PAX3-FOXO1.Hs-352-Sk_PAX3-FOXO1-vector 195 bp overlap
PHF8 1 dataset
ChIP WA01 ENCSR000ATK.PHF8.WA01 262 bp overlap
POLR2A 3 datasets
ChIP H1 ENCFF566JSR 537 bp overlap
ChIP H1 ENCFF566JSR 631 bp overlap
ChIP vagina ENCFF305NWS 293 bp overlap
POU2F3 1 dataset
ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 315 bp overlap
POU5F1 4 datasets
ChIP HUES-8 GSE109524.POU5F1.HUES-8 632 bp overlap
ChIP SKM-1 GSE93706.POU5F1.SKM-1 285 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 369 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 231 bp overlap
PPARD 1 dataset
Motif ES_0h ES_0h-PPARD_MA1550.2 14 bp overlap
PPARG 1 dataset
ChIP HUVEC-C_PPARG_HYPO GSE50144.PPARG.HUVEC-C_PPARG_HYPO 96 bp overlap
PRDM9 2 datasets
Motif ES_0h ES_0h-PRDM9_MA1723.2 20 bp overlap
Motif ES_0h ES_0h-PRDM9_MA1723.2 20 bp overlap
Prdm5 1 dataset
Motif ES_0h ES_0h-Prdm5_MA1999.2 11 bp overlap
RAD21 1 dataset
ChIP HEK293_siE1A GSE130135.RAD21.HEK293_siE1A 324 bp overlap
RBBP5 2 datasets
ChIP H1 ENCFF905HFL 408 bp overlap
ChIP WA01 ENCSR000AQC.RBBP5.WA01 714 bp overlap
RBM39 1 dataset
ChIP K-562 ENCSR764OXF.RBM39.K-562 181 bp overlap
RBPJ 1 dataset
Motif ES_0h ES_0h-RBPJ_MA1116.2 6 bp overlap
REST 2 datasets
ChIP K-562 ENCSR137ZMQ.REST.K-562 196 bp overlap
ChIP K562 ENCFF688UKW 237 bp overlap
RREB1 1 dataset
Motif ES_0h ES_0h-RREB1_MA0073.2 19 bp overlap
RXRB 1 dataset
Motif ES_0h ES_0h-RXRB_MA0855.1 14 bp overlap
SIN3A 1 dataset
ChIP H1 ENCFF042ZSL 521 bp overlap
SMAD1 1 dataset
ChIP BG03 GSE36578.SMAD1.BG03 96 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 141 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 478 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 175 bp overlap
SMARCA4 6 datasets
ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 322 bp overlap
ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 294 bp overlap
ChIP NSC GSE125033.SMARCA4.NSC 528 bp overlap
ChIP NSC GSE125033.SMARCA4.NSC 256 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 745 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 189 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 179 bp overlap
SMARCC1 2 datasets
ChIP ESC S25-ESC-d0-BAF155-exp1 560 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 195 bp overlap
SMC1A 1 dataset
ChIP monocyte_INFg GSE98367.SMC1A.monocyte_INFg 133 bp overlap
SOX2 5 datasets
ChIP HNSC GSE69479.SOX2.HNSC 78 bp overlap
ChIP HNSC GSE69479.SOX2.HNSC 374 bp overlap
ChIP hiPSC GSE67282.SOX2.hiPSC 211 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 178 bp overlap
ChIP hiPSC_KDP53 GSE67282.SOX2.hiPSC_KDP53 300 bp overlap
SOX21 1 dataset
ChIP neuroepithelilal-cells GSE110505.SOX21.neuroepithelilal-cells 309 bp overlap
SP1 4 datasets
ChIP H1 ENCFF263FUH 321 bp overlap
ChIP H1 ENCFF263FUH 321 bp overlap
ChIP WA01 ENCSR000BIR.SP1.WA01 416 bp overlap
ChIP WTC11 ENCFF688PEU 501 bp overlap
SP2 1 dataset
Motif ES_0h ES_0h-SP2_MA0516.3 9 bp overlap
SP4 1 dataset
Motif ES_0h ES_0h-SP4_MA0685.2 9 bp overlap
SP5 1 dataset
Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap
STAT3 3 datasets
ChIP monocyte_IFNg GSE120943.STAT3.monocyte_IFNg 141 bp overlap
ChIP monocyte_IL10 GSE120943.STAT3.monocyte_IL10 142 bp overlap
ChIP monocyte_resting GSE120943.STAT3.monocyte_resting 130 bp overlap
TAF1 2 datasets
ChIP H1 ENCFF478SZO 485 bp overlap
ChIP WA01 ENCSR000BHO.TAF1.WA01 231 bp overlap
TBP 5 datasets
ChIP hESC GSE122298.TBP.hESC 113 bp overlap
ChIP hESC GSE122298.TBP.hESC 212 bp overlap
ChIP hESC_10h GSE122298.TBP.hESC_10h 169 bp overlap
ChIP hESC_10h GSE122298.TBP.hESC_10h 117 bp overlap
ChIP hESC_8h GSE122298.TBP.hESC_8h 110 bp overlap
TEAD1 2 datasets
Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap
ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 117 bp overlap
TEAD3 1 dataset
Motif ES_0h ES_0h-TEAD3_MA0808.1 8 bp overlap
TEAD4 2 datasets
ChIP BJ_fibroblast_CD13-neg GSE114367.TEAD4.BJ_fibroblast_CD13-neg 150 bp overlap
ChIP H1 ENCFF778PAX 168 bp overlap
TFAP4 3 datasets
Motif ES_0h ES_0h-TFAP4_MA0691.1 10 bp overlap
ChIP Hep-G2 ENCSR103SZL.TFAP4.Hep-G2 138 bp overlap
ChIP HepG2 ENCFF030SRU 223 bp overlap
TP53 1 dataset
ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 390 bp overlap
TRIM28 1 dataset
ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 282 bp overlap
Tcf12 1 dataset
Motif ES_0h ES_0h-Tcf12_MA0521.3 6 bp overlap
Tfcp2l1 1 dataset
Motif ES_0h ES_0h-Tfcp2l1_MA0145.2 14 bp overlap
Twist2 1 dataset
Motif ES_0h ES_0h-Twist2_MA0633.3 6 bp overlap
USF1 3 datasets
ChIP H1 ENCFF090WVU 130 bp overlap
ChIP K-562 ENCSR000BKT.USF1.K-562 56 bp overlap
ChIP WA01 ENCSR000BIU.USF1.WA01 136 bp overlap
VDR 1 dataset
ChIP kidney-cortex GSE129585.VDR.kidney-cortex 533 bp overlap
Wt1 1 dataset
Motif ES_0h ES_0h-Wt1_MA1627.2 10 bp overlap
YY1 1 dataset
ChIP WA01 ENCSR000BKD.YY1.WA01 151 bp overlap
ZKSCAN1 1 dataset
Motif ES_0h ES_0h-ZKSCAN1_MA1585.2 9 bp overlap
ZKSCAN5 1 dataset
Motif ES_0h ES_0h-ZKSCAN5_MA1652.2 9 bp overlap
ZNF148 2 datasets
Motif ES_0h ES_0h-ZNF148_MA1653.2 10 bp overlap
ChIP K-562 GSE121133.ZNF148.K-562 298 bp overlap
ZNF18 1 dataset
ChIP HepG2 ENCFF479ZIQ 410 bp overlap
ZNF184 1 dataset
Motif ES_0h ES_0h-ZNF184_MA2120.1 13 bp overlap
ZNF257 1 dataset
Motif ES_0h ES_0h-ZNF257_MA1710.2 10 bp overlap
ZNF263 1 dataset
Motif ES_0h ES_0h-ZNF263_MA0528.3 7 bp overlap
ZNF281 2 datasets
Motif ES_0h ES_0h-ZNF281_MA1630.3 10 bp overlap
ChIP K-562 GSE121133.ZNF281.K-562 265 bp overlap
ZNF319 2 datasets
ChIP K-562 ENCSR231PDA.ZNF319.K-562 452 bp overlap
ChIP K562 ENCFF561ZSB 261 bp overlap
ZNF366 1 dataset
ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 281 bp overlap
ZNF460 1 dataset
Motif ES_0h ES_0h-ZNF460_MA1596.1 16 bp overlap
ZNF462 1 dataset
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 145 bp overlap
ZNF530 1 dataset
Motif ES_0h ES_0h-ZNF530_MA1981.2 14 bp overlap
ZNF596 2 datasets
ChIP HEK293 ENCFF854MGB 168 bp overlap
ChIP HEK293 ENCSR344SBD.ZNF596.HEK293 334 bp overlap
ZNF684 1 dataset
Motif ES_0h ES_0h-ZNF684_MA1600.2 14 bp overlap
ZNF85 1 dataset
Motif ES_0h ES_0h-ZNF85_MA1720.2 12 bp overlap
Zfp809 1 dataset
Motif ES_0h ES_0h-Zfp809_MA2125.1 9 bp overlap
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