chr2:64,251,480–64,252,200

chr2 : 64,251,480 – 64,252,200

720 bp 104 TFs 7 linked genes

This 720 bp open chromatin element is linked to 7 target genes and is bound by 104 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000288932		22.0 kb	Distal	Multiome
ENSG00000225889		23.3 kb	Distal	Multiome
PELI1		107.3 kb	Distal	Multiome+HiCAR
LGALSL-DT		202.3 kb	Distal	Multiome
LGALSL		202.8 kb	Distal	Multiome
VPS54		232.2 kb	Distal	Multiome
AFTPH		272.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

104 transcription factors

ChIP HCT-116 GSE103894.APC.HCT-116 292 bp overlap

ARNTL 1 dataset

ChIP U2OS_DMSO GSE85096.ARNTL.U2OS_DMSO 306 bp overlap

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 378 bp overlap

ChIP H1 ENCFF399KAM 720 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 719 bp overlap

ATF2 4 datasets

ChIP H1 ENCFF295GZO 509 bp overlap

ChIP H1 ENCFF295GZO 571 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 530 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 104 bp overlap

BCOR 6 datasets

ChIP B-cell_GERMINAL_CENTER GSE43350.BCOR.B-cell_GERMINAL_CENTER 171 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 196 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 162 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 190 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 278 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 175 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 230 bp overlap

BRD4 2 datasets

ChIP hESC GSE33281.BRD4.hESC 86 bp overlap

ChIP hESC GSE33281.BRD4.hESC 70 bp overlap

ChIP H9 GSE94418.BRF1.H9 191 bp overlap

Bcl11B 1 dataset

Motif ES_0h ES_0h-Bcl11B_MA1989.2 9 bp overlap

CHD1 2 datasets

ChIP WA01 ENCSR000AQK.CHD1.WA01 720 bp overlap

ChIP WA01 ENCSR000EBU.CHD1.WA01 91 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 345 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 173 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 298 bp overlap

E2F6 2 datasets

ChIP WA01 ENCSR000BSI.E2F6.WA01 142 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 118 bp overlap

Motif ES_0h ES_0h-EGR1_MA0162.5 10 bp overlap

ChIP hESC ENCSR534VHI.ETS1.hESC 132 bp overlap

ChIP WTC11 ENCFF812SCD 437 bp overlap

EWSR1-FLI1 1 dataset

Motif ES_0h ES_0h-EWSR1-FLI1_MA0149.1 18 bp overlap

FEZF2 1 dataset

Motif ES_0h ES_0h-FEZF2_MA2341.1 8 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 296 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 182 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 375 bp overlap

Motif ES_0h ES_0h-HIC2_MA0738.2 6 bp overlap

HNRNPK 4 datasets

ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 276 bp overlap

ChIP Hep-G2 ENCSR519QAA.HNRNPK.Hep-G2 234 bp overlap

ChIP K-562 GSE120104.HNRNPK.K-562 170 bp overlap

ChIP K-562 ENCSR014RCS.HNRNPK.K-562 169 bp overlap

IKZF2 1 dataset

Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 399 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 458 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 472 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 515 bp overlap

KDM4A 1 dataset

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 261 bp overlap

Motif ES_0h ES_0h-KLF1_MA0493.3 8 bp overlap

KLF10 2 datasets

Motif ES_0h ES_0h-KLF10_MA1511.2 9 bp overlap

Motif ES_0h ES_0h-KLF10_MA1511.2 9 bp overlap

KLF11 2 datasets

Motif ES_0h ES_0h-KLF11_MA1512.2 10 bp overlap

Motif ES_0h ES_0h-KLF11_MA1512.2 10 bp overlap

KLF12 1 dataset

Motif ES_0h ES_0h-KLF12_MA0742.2 9 bp overlap

KLF14 1 dataset

Motif ES_0h ES_0h-KLF14_MA0740.2 9 bp overlap

KLF16 2 datasets

Motif ES_0h ES_0h-KLF16_MA0741.1 11 bp overlap

Motif ES_0h ES_0h-KLF16_MA0741.1 11 bp overlap

Motif ES_0h ES_0h-KLF2_MA1515.2 8 bp overlap

Motif ES_0h ES_0h-KLF4_MA0039.5 8 bp overlap

Motif ES_0h ES_0h-KLF5_MA0599.1 10 bp overlap

Motif ES_0h ES_0h-KLF6_MA1517.2 9 bp overlap

Motif ES_0h ES_0h-KLF9_MA1107.3 11 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 169 bp overlap

Motif ES_0h ES_0h-MAZ_MA1522.2 8 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 720 bp overlap

MORC2 2 datasets

ChIP H9 GSE95374.MORC2.H9 411 bp overlap

ChIP H9 GSE95374.MORC2.H9 164 bp overlap

ChIP H1 ENCFF963FZS 299 bp overlap

NANOG 10 datasets

ChIP GM23338 ENCFF065NZG 276 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 131 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 720 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 443 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 148 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 720 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 720 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 614 bp overlap

ChIP hESC GSE20650.NANOG.hESC 325 bp overlap

ChIP hESC GSE18292.NANOG.hESC 154 bp overlap

NFIC::TLX1 1 dataset

Motif ES_0h ES_0h-NFICTLX1_MA0119.1 14 bp overlap

Motif ES_0h ES_0h-NFIX_MA1528.2 14 bp overlap

NFYB 2 datasets

ChIP K-562 GSE26439.NFYB.K-562 265 bp overlap

ChIP WTC11 ENCFF751ZTQ 391 bp overlap

NIPBL 1 dataset

ChIP WA09 GSE105028.NIPBL.WA09 571 bp overlap

PATZ1 1 dataset

Motif ES_0h ES_0h-PATZ1_MA1961.2 11 bp overlap

POLR2A 4 datasets

ChIP GM23338 ENCFF450WCS 269 bp overlap

ChIP H1 ENCFF566JSR 327 bp overlap

ChIP H1 ENCFF770YBQ 471 bp overlap

ChIP H1 ENCFF833NJP 411 bp overlap

POU5F1 10 datasets

ChIP HUES-8 GSE109524.POU5F1.HUES-8 520 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 130 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 245 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 667 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 251 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 197 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 720 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 712 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 301 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 146 bp overlap

PRDM9 1 dataset

Motif ES_0h ES_0h-PRDM9_MA1723.2 20 bp overlap

RAD21 4 datasets

ChIP H1 ENCFF698EWO 241 bp overlap

ChIP H1 ENCFF967OJF 244 bp overlap

ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 388 bp overlap

ChIP hiPSC_IV8 GSE106870.RAD21.hiPSC_IV8 181 bp overlap

RBBP5 2 datasets

ChIP WA01 ENCSR000AQC.RBBP5.WA01 136 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 338 bp overlap

ChIP K562 ENCFF809XVG 107 bp overlap

RREB1 1 dataset

Motif ES_0h ES_0h-RREB1_MA0073.2 19 bp overlap

RUNX3 1 dataset

Motif ES_0h ES_0h-RUNX3_MA0684.3 8 bp overlap

Runx1 1 dataset

Motif ES_0h ES_0h-Runx1_MA0002.3 9 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 531 bp overlap

SIN3A 6 datasets

ChIP H1 ENCFF042ZSL 521 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 447 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 113 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 468 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 192 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 228 bp overlap

SMAD1 1 dataset

ChIP BG03 GSE36578.SMAD1.BG03 219 bp overlap

SMAD3 1 dataset

ChIP BG03 GSE21614.SMAD3.BG03 209 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 325 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 238 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 250 bp overlap

SMARCC1 5 datasets

ChIP DE_D1 S10-DE-d1-BAF155-exp1 282 bp overlap

ChIP ESC S25-ESC-d0-BAF155-exp1 338 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 243 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 269 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 529 bp overlap

SOX10 1 dataset

Motif ES_0h ES_0h-SOX10_MA0442.3 6 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 161 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 347 bp overlap

Motif ES_0h ES_0h-SOX4_MA0867.3 8 bp overlap

Motif ES_0h ES_0h-SP1_MA0079.5 9 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 548 bp overlap

ChIP WTC11 ENCFF688PEU 361 bp overlap

Motif ES_0h ES_0h-SP2_MA0516.3 9 bp overlap

Motif ES_0h ES_0h-SP3_MA0746.3 11 bp overlap

Motif ES_0h ES_0h-SP4_MA0685.2 9 bp overlap

Motif ES_0h ES_0h-SP4_MA0685.2 9 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 613 bp overlap

Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap

Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap

Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap

Motif ES_0h ES_0h-SP8_MA0747.2 11 bp overlap

Motif ES_0h ES_0h-SP9_MA1564.2 10 bp overlap

Motif ES_0h ES_0h-SPIB_MA0081.3 13 bp overlap

Sox11 1 dataset

Motif ES_0h ES_0h-Sox11_MA0869.3 8 bp overlap

Motif ES_0h ES_0h-Sox6_MA0515.1 10 bp overlap

Motif ES_0h ES_0h-Spi1_MA0080.7 13 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 485 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 465 bp overlap

ChIP hESC GSE17917.TAF2.hESC 159 bp overlap

TAF7 2 datasets

ChIP H1 ENCFF061XZZ 337 bp overlap

ChIP WA01 ENCSR000BLU.TAF7.WA01 379 bp overlap

ChIP H1 ENCFF859IIO 377 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 496 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 128 bp overlap

ChIP hESC GSE122298.TBP.hESC 700 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 661 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 720 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 610 bp overlap

Motif ES_0h ES_0h-TBX5_MA0807.1 8 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 142 bp overlap

TFAP2A 1 dataset

Motif ES_0h ES_0h-TFAP2A_MA0810.2 11 bp overlap

TFAP2B 1 dataset

Motif ES_0h ES_0h-TFAP2B_MA0811.2 11 bp overlap

TFAP2C 3 datasets

Motif ES_0h ES_0h-TFAP2C_MA0524.3 11 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 720 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 707 bp overlap

ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 204 bp overlap

Motif ES_0h ES_0h-Wt1_MA1627.2 10 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 269 bp overlap

ZFP36 1 dataset

ChIP K-562 ENCSR776CYN.ZFP36.K-562 138 bp overlap

ZKSCAN5 2 datasets

Motif ES_0h ES_0h-ZKSCAN5_MA1652.2 9 bp overlap

Motif ES_0h ES_0h-ZKSCAN5_MA1652.2 9 bp overlap

ZNF114 1 dataset

ChIP GM23338 ENCFF631OSW 357 bp overlap

ZNF143 1 dataset

ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 224 bp overlap

ZNF148 4 datasets

Motif ES_0h ES_0h-ZNF148_MA1653.2 10 bp overlap

ChIP K-562 GSE121133.ZNF148.K-562 314 bp overlap

ChIP K-562 ENCSR018MSO.ZNF148.K-562 291 bp overlap

ChIP K562 ENCFF352SDL 472 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 711 bp overlap

ZNF213 1 dataset

Motif ES_0h ES_0h-ZNF213_MA2121.1 12 bp overlap

ZNF263 2 datasets

Motif ES_0h ES_0h-ZNF263_MA0528.3 7 bp overlap

Motif ES_0h ES_0h-ZNF263_MA0528.3 7 bp overlap

ZNF281 2 datasets

Motif ES_0h ES_0h-ZNF281_MA1630.3 10 bp overlap

ChIP K-562 GSE121133.ZNF281.K-562 243 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 475 bp overlap

ZNF532 2 datasets

ChIP WTC11 ENCFF373VBX 263 bp overlap

ChIP WTC11 ENCFF373VBX 285 bp overlap

ZNF740 1 dataset

Motif ES_0h ES_0h-ZNF740_MA0753.3 10 bp overlap

Motif ES_0h ES_0h-Zfx_MA0146.3 10 bp overlap