chr2 : 63,950,012 – 63,950,802
790 bp 117 TFs 4 linked genes
This 790 bp open chromatin element is linked to 4 target genes and is bound by 117 transcription factors.
Linked Genes
4 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
VPS54 68.8 kb Distal Multiome
UGP2 109.6 kb Distal Multiome
PELI1 193.8 kb Distal Multiome
ENSG00000225889 277.8 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:63,945,012 – 63,955,802
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
117 transcription factors
Source
Cell type
AGO2 3 datasets
ChIP HepG2 ENCFF252VFI 176 bp overlap
ChIP HepG2 ENCFF252VFI 386 bp overlap
ChIP HepG2 ENCFF773YDL 176 bp overlap
ARID3A 1 dataset
ChIP HepG2 ENCFF341DES 395 bp overlap
ARID5B 1 dataset
ChIP HepG2 ENCFF964FWK 182 bp overlap
ATF2 2 datasets
Motif DE_48h DE_48h-ATF2_MA1632.2 10 bp overlap
Motif DE_60h DE_60h-ATF2_MA1632.2 10 bp overlap
ATM 1 dataset
ChIP HepG2 ENCFF686TFU 331 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 224 bp overlap
ChIP K562 ENCFF673OEZ 302 bp overlap
CEBPA 3 datasets
Motif DE_48h DE_48h-CEBPA_MA0102.5 10 bp overlap
Motif DE_60h DE_60h-CEBPA_MA0102.5 10 bp overlap
ChIP HepG2 ENCFF175DFS 290 bp overlap
CEBPD 2 datasets
Motif DE_48h DE_48h-CEBPD_MA0836.3 8 bp overlap
Motif DE_60h DE_60h-CEBPD_MA0836.3 8 bp overlap
CREB1 4 datasets
Motif DE_48h DE_48h-CREB1_MA0018.5 8 bp overlap
Motif DE_60h DE_60h-CREB1_MA0018.5 8 bp overlap
ChIP HepG2 ENCFF576ERP 539 bp overlap
ChIP HepG2 ENCFF576ERP 338 bp overlap
CREM 2 datasets
ChIP Hep-G2 ENCSR903ELW.CREM.Hep-G2 313 bp overlap
ChIP HepG2 ENCFF049UDY 460 bp overlap
ELF1 5 datasets
Motif DE_48h DE_48h-ELF1_MA0473.4 9 bp overlap
Motif DE_72h DE_72h-ELF1_MA0473.4 9 bp overlap
ChIP Hep-G2 ENCSR321VGW.ELF1.Hep-G2 175 bp overlap
ChIP HepG2 ENCFF367ZWV 421 bp overlap
ChIP HepG2 ENCFF838BCU 277 bp overlap
ELF3 2 datasets
Motif DE_48h DE_48h-ELF3_MA0640.3 9 bp overlap
Motif DE_72h DE_72h-ELF3_MA0640.3 9 bp overlap
EOMES 2 datasets
ChIP hESC GSE26097.EOMES.hESC 288 bp overlap
ChIP hESC GSE26097.EOMES.hESC 231 bp overlap
EP300 2 datasets
ChIP Hep-G2 ENCSR000BLW.EP300.Hep-G2 351 bp overlap
ChIP HepG2 ENCFF354ACD 325 bp overlap
ERF::FOXI1 2 datasets
Motif DE_48h DE_48h-ERFFOXI1_MA1935.2 10 bp overlap
Motif DE_72h DE_72h-ERFFOXI1_MA1935.2 10 bp overlap
ERF::FOXO1 2 datasets
Motif DE_48h DE_48h-ERFFOXO1_MA1936.2 12 bp overlap
Motif DE_60h DE_60h-ERFFOXO1_MA1936.2 12 bp overlap
ETV1 2 datasets
Motif DE_48h DE_48h-ETV1_MA0761.3 9 bp overlap
Motif DE_72h DE_72h-ETV1_MA0761.3 9 bp overlap
ETV2::FOXI1 4 datasets
Motif DE_48h DE_48h-ETV2FOXI1_MA1942.2 11 bp overlap
Motif DE_48h DE_48h-ETV2FOXI1_MA1942.2 11 bp overlap
Motif DE_60h DE_60h-ETV2FOXI1_MA1942.2 11 bp overlap
Motif DE_72h DE_72h-ETV2FOXI1_MA1942.2 11 bp overlap
ETV4 2 datasets
ChIP Hep-G2 ENCSR714YZG.ETV4.Hep-G2 251 bp overlap
ChIP HepG2 ENCFF534CDD 410 bp overlap
ETV5 1 dataset
ChIP HepG2 ENCFF456LSA 371 bp overlap
ETV5::FOXI1 2 datasets
Motif DE_48h DE_48h-ETV5FOXI1_MA1946.2 12 bp overlap
Motif DE_60h DE_60h-ETV5FOXI1_MA1946.2 12 bp overlap
EWSR1-FLI1 2 datasets
Motif DE_48h DE_48h-EWSR1-FLI1_MA0149.1 18 bp overlap
Motif DE_72h DE_72h-EWSR1-FLI1_MA0149.1 18 bp overlap
Elf5 1 dataset
Motif DE_48h DE_48h-Elf5_MA0136.4 8 bp overlap
Erg 2 datasets
Motif DE_48h DE_48h-Erg_MA0474.4 10 bp overlap
Motif DE_72h DE_72h-Erg_MA0474.4 10 bp overlap
FLI1::FOXI1 2 datasets
Motif DE_48h DE_48h-FLI1FOXI1_MA1950.2 11 bp overlap
Motif DE_72h DE_72h-FLI1FOXI1_MA1950.2 11 bp overlap
FOSL2 1 dataset
ChIP HepG2 ENCFF548CXY 357 bp overlap
FOXA1 3 datasets
ChIP HepG2 ENCFF207NVJ 71 bp overlap
ChIP HepG2 ENCFF361KNY 285 bp overlap
ChIP HepG2 ENCFF740VZW 108 bp overlap
FOXA2 5 datasets
ChIP DE DE-FOXA2-1 790 bp overlap
ChIP DE DE-FOXA2-2 790 bp overlap
ChIP HepG2 ENCFF533COJ 297 bp overlap
ChIP HepG2 ENCFF570ABM 230 bp overlap
ChIP HepG2 ENCFF894AYY 353 bp overlap
FOXK1 1 dataset
ChIP HepG2 ENCFF635XWY 375 bp overlap
FOXO1::ELK1 4 datasets
Motif DE_48h DE_48h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_60h DE_60h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_72h DE_72h-FOXO1ELK1_MA1954.2 13 bp overlap
FOXO1::ELK3 4 datasets
Motif DE_48h DE_48h-FOXO1ELK3_MA1955.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1ELK3_MA1955.2 13 bp overlap
Motif DE_60h DE_60h-FOXO1ELK3_MA1955.2 13 bp overlap
Motif DE_72h DE_72h-FOXO1ELK3_MA1955.2 13 bp overlap
FOXP1 1 dataset
ChIP Hep-G2 ENCSR369YUK.FOXP1.Hep-G2 198 bp overlap
FOXP4 2 datasets
ChIP Hep-G2 ENCSR232LLP.FOXP4.Hep-G2 284 bp overlap
ChIP HepG2 ENCFF462ULY 329 bp overlap
GABPA 2 datasets
Motif DE_48h DE_48h-GABPA_MA0062.4 10 bp overlap
Motif DE_72h DE_72h-GABPA_MA0062.4 10 bp overlap
GATA1 4 datasets
ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 172 bp overlap
ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 184 bp overlap
ChIP K-562 GSE107726.GATA1.K-562 290 bp overlap
ChIP erythroid_Don001 GSE137982.GATA1.erythroid_Don001 243 bp overlap
GATA2 4 datasets
ChIP Hep-G2 ENCSR897LDT.GATA2.Hep-G2 512 bp overlap
ChIP HepG2 ENCFF905PYM 356 bp overlap
ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 191 bp overlap
ChIP TF1 GSE73207.GATA2.TF1 270 bp overlap
GATA4 7 datasets
ChIP DE DE-GATA4-1 790 bp overlap
ChIP DE DE-GATA4-2 790 bp overlap
ChIP ESO-26 GSE132813.GATA4.ESO-26 440 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 367 bp overlap
ChIP Hep-G2 ENCSR590CNM.GATA4.Hep-G2 264 bp overlap
ChIP HepG2 ENCFF309FOQ 356 bp overlap
ChIP foregut GSE117136.GATA4.foregut 470 bp overlap
GATA6 14 datasets
ChIP AGS GSE51705.GATA6.AGS 151 bp overlap
ChIP AGS GSE51705.GATA6.AGS 330 bp overlap
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 246 bp overlap
ChIP DE DE-GATA6-1 790 bp overlap
ChIP DE DE-GATA6-2 790 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 790 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 790 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 790 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 790 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 790 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 790 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 790 bp overlap
ChIP foregut GSE117136.GATA6.foregut 263 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 253 bp overlap
GATAD2A 1 dataset
ChIP HepG2 ENCFF252XNH 119 bp overlap
GFI1 1 dataset
ChIP HepG2 ENCFF472INF 394 bp overlap
HDAC2 3 datasets
ChIP Hep-G2 ENCSR000BMC.HDAC2.Hep-G2 149 bp overlap
ChIP HepG2 ENCFF087XCR 337 bp overlap
ChIP HepG2 ENCFF990GUQ 419 bp overlap
HLF 2 datasets
ChIP Hep-G2 ENCSR528PSI.HLF.Hep-G2 185 bp overlap
ChIP HepG2 ENCFF854JLR 90 bp overlap
HMG20B 1 dataset
ChIP HepG2 ENCFF756WYV 308 bp overlap
HNF1A 1 dataset
ChIP HepG2 ENCFF540TRC 514 bp overlap
Hoxa13 1 dataset
Motif DE_48h DE_48h-Hoxa13_MA0650.4 8 bp overlap
IKZF1 2 datasets
Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap
Motif DE_72h DE_72h-IKZF1_MA1508.2 8 bp overlap
IKZF2 3 datasets
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap
ISL2 2 datasets
ChIP Hep-G2 ENCSR492IHH.ISL2.Hep-G2 427 bp overlap
ChIP HepG2 ENCFF742RIP 213 bp overlap
Ikzf3 2 datasets
Motif DE_48h DE_48h-Ikzf3_MA1992.2 9 bp overlap
Motif DE_72h DE_72h-Ikzf3_MA1992.2 9 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 325 bp overlap
KAT8 1 dataset
ChIP HepG2 ENCFF890JFC 487 bp overlap
LCOR 1 dataset
ChIP HepG2 ENCFF499KCU 391 bp overlap
Lhx3 1 dataset
Motif DE_48h DE_48h-Lhx3_MA0135.2 12 bp overlap
MED1 2 datasets
ChIP Hep-G2 ENCSR959XNY.MED1.Hep-G2 333 bp overlap
ChIP HepG2 ENCFF495TSS 387 bp overlap
MYBL2 1 dataset
ChIP Hep-G2 ENCSR581KCO.MYBL2.Hep-G2 127 bp overlap
NCOA2 1 dataset
ChIP HepG2 ENCFF853BJJ 190 bp overlap
NFIA 2 datasets
ChIP Hep-G2 GSE97661.NFIA.Hep-G2 215 bp overlap
ChIP HepG2 ENCFF815HWK 208 bp overlap
NFIC 5 datasets
ChIP Hep-G2 ENCSR000BQX.NFIC.Hep-G2 226 bp overlap
ChIP HepG2 ENCFF169TKU 447 bp overlap
ChIP K-562 ENCSR796ITY.NFIC.K-562 234 bp overlap
ChIP K562 ENCFF167YID 457 bp overlap
ChIP K562 ENCFF167YID 277 bp overlap
NR2F6 2 datasets
ChIP HepG2 ENCFF429VKC 393 bp overlap
ChIP HepG2 ENCFF429VKC 178 bp overlap
NR5A1 1 dataset
ChIP Hep-G2 ENCSR310OZS.NR5A1.Hep-G2 163 bp overlap
PAXIP1 3 datasets
ChIP Hep-G2 ENCSR530ARJ.PAXIP1.Hep-G2 301 bp overlap
ChIP HepG2 ENCFF526NOJ 456 bp overlap
ChIP HepG2 ENCFF526NOJ 249 bp overlap
PHF21A 3 datasets
ChIP Hep-G2 ENCSR315VYZ.PHF21A.Hep-G2 196 bp overlap
ChIP HepG2 ENCFF525EUW 474 bp overlap
ChIP HepG2 ENCFF525EUW 273 bp overlap
PITX1 1 dataset
ChIP HepG2 ENCFF468QTQ 382 bp overlap
POGZ 1 dataset
ChIP HepG2 ENCFF153UUK 507 bp overlap
POU1F1 2 datasets
Motif DE_48h DE_48h-POU1F1_MA0784.3 14 bp overlap
Motif DE_60h DE_60h-POU1F1_MA0784.3 14 bp overlap
POU2F2 2 datasets
Motif DE_48h DE_48h-POU2F2_MA0507.3 13 bp overlap
Motif DE_60h DE_60h-POU2F2_MA0507.3 13 bp overlap
POU3F2 2 datasets
Motif DE_48h DE_48h-POU3F2_MA0787.1 12 bp overlap
Motif DE_60h DE_60h-POU3F2_MA0787.1 12 bp overlap
POU3F3 2 datasets
Motif DE_48h DE_48h-POU3F3_MA0788.1 13 bp overlap
Motif DE_60h DE_60h-POU3F3_MA0788.1 13 bp overlap
PPARG 1 dataset
ChIP Hep-G2 ENCSR130VQL.PPARG.Hep-G2 195 bp overlap
Prdm15 2 datasets
Motif DE_48h DE_48h-Prdm15_MA1616.2 11 bp overlap
Motif DE_72h DE_72h-Prdm15_MA1616.2 11 bp overlap
RARA 1 dataset
ChIP HepG2 ENCFF582XUA 357 bp overlap
RERE 1 dataset
ChIP HepG2 ENCFF145QRA 381 bp overlap
RXRB 1 dataset
ChIP HepG2 ENCFF539ZAY 374 bp overlap
SAP130 1 dataset
ChIP HepG2 ENCFF892EHZ 411 bp overlap
SATB1 1 dataset
Motif DE_48h DE_48h-SATB1_MA1963.2 7 bp overlap
SIX1 3 datasets
Motif DE_48h DE_48h-SIX1_MA1118.2 9 bp overlap
Motif DE_60h DE_60h-SIX1_MA1118.2 9 bp overlap
ChIP Hep-G2 ENCSR561BQM.SIX1.Hep-G2 225 bp overlap
SIX2 2 datasets
Motif DE_48h DE_48h-SIX2_MA1119.2 11 bp overlap
Motif DE_60h DE_60h-SIX2_MA1119.2 11 bp overlap
SIX4 1 dataset
ChIP HepG2 ENCFF372NPG 341 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 790 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 790 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 428 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 438 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 790 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 412 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 790 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 790 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 368 bp overlap
SOX13 2 datasets
ChIP HepG2 ENCFF062VSQ 388 bp overlap
ChIP HepG2 ENCFF231PAK 341 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 790 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 790 bp overlap
SOX5 1 dataset
ChIP HepG2 ENCFF470KZD 233 bp overlap
SOX6 2 datasets
ChIP Hep-G2 ENCSR766TSU.SOX6.Hep-G2 359 bp overlap
ChIP HepG2 ENCFF767OCK 510 bp overlap
SP1 1 dataset
ChIP HepG2 ENCFF123KAM 325 bp overlap
SPIB 2 datasets
Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap
Motif DE_72h DE_72h-SPIB_MA0081.3 13 bp overlap
SPIC 2 datasets
Motif DE_48h DE_48h-SPIC_MA0687.2 13 bp overlap
Motif DE_60h DE_60h-SPIC_MA0687.2 13 bp overlap
SSRP1 1 dataset
ChIP HepG2 ENCFF540BLL 430 bp overlap
Six4 2 datasets
Motif DE_48h DE_48h-Six4_MA2001.2 7 bp overlap
Motif DE_60h DE_60h-Six4_MA2001.2 7 bp overlap
Spi1 2 datasets
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
Motif DE_72h DE_72h-Spi1_MA0080.7 13 bp overlap
Stat2 2 datasets
Motif DE_48h DE_48h-Stat2_MA1623.2 10 bp overlap
Motif DE_60h DE_60h-Stat2_MA1623.2 10 bp overlap
TAL1 1 dataset
ChIP ProEs GSE59087.TAL1.ProEs 165 bp overlap
TBX2 2 datasets
ChIP Hep-G2 ENCSR410FEH.TBX2.Hep-G2 260 bp overlap
ChIP HepG2 ENCFF811TLA 457 bp overlap
TCF7 2 datasets
ChIP Hep-G2 ENCSR444LIN.TCF7.Hep-G2 332 bp overlap
ChIP HepG2 ENCFF628OFQ 217 bp overlap
TCF7L2 2 datasets
ChIP Hep-G2 ENCSR346BOD.TCF7L2.Hep-G2 290 bp overlap
ChIP HepG2 ENCFF510OLG 399 bp overlap
TEF 1 dataset
ChIP HepG2 ENCFF661AUQ 381 bp overlap
TFAP4 4 datasets
ChIP DLD-1 GSE46935.TFAP4.DLD-1 348 bp overlap
ChIP Hep-G2 ENCSR103SZL.TFAP4.Hep-G2 176 bp overlap
ChIP HepG2 ENCFF030SRU 331 bp overlap
ChIP HepG2 ENCFF932XOY 168 bp overlap
TFE3 1 dataset
ChIP Hep-G2 ENCSR589SNT.TFE3.Hep-G2 172 bp overlap
TGIF2 2 datasets
ChIP HepG2 ENCFF421ZJN 344 bp overlap
ChIP HepG2 ENCFF421ZJN 145 bp overlap
THRB 1 dataset
Motif DE_48h DE_48h-THRB_MA1576.2 18 bp overlap
ZBTB7A 2 datasets
Motif DE_48h DE_48h-ZBTB7A_MA0750.3 9 bp overlap
Motif DE_72h DE_72h-ZBTB7A_MA0750.3 9 bp overlap
ZBTB7B 2 datasets
ChIP Hep-G2 ENCSR322ULL.ZBTB7B.Hep-G2 161 bp overlap
ChIP HepG2 ENCFF763OCV 452 bp overlap
ZGPAT 1 dataset
ChIP Hep-G2 ENCSR704IGU.ZGPAT.Hep-G2 379 bp overlap
ZIM3 2 datasets
Motif DE_48h DE_48h-ZIM3_MA1709.2 11 bp overlap
Motif DE_60h DE_60h-ZIM3_MA1709.2 11 bp overlap
ZMYM4 1 dataset
ChIP HepG2 ENCFF567SQY 440 bp overlap
ZNF12 1 dataset
ChIP Hep-G2 ENCSR711KBM.ZNF12.Hep-G2 116 bp overlap
ZNF175 2 datasets
Motif DE_48h DE_48h-ZNF175_MA2332.1 9 bp overlap
Motif DE_72h DE_72h-ZNF175_MA2332.1 9 bp overlap
ZNF24 1 dataset
ChIP Hep-G2 ENCSR362NWP.ZNF24.Hep-G2 207 bp overlap
ZNF264 2 datasets
ChIP Hep-G2 ENCSR248BVU.ZNF264.Hep-G2 448 bp overlap
ChIP HepG2 ENCFF453WJV 287 bp overlap
ZNF324 1 dataset
Motif DE_48h DE_48h-ZNF324_MA1977.2 14 bp overlap
ZNF382 2 datasets
ChIP HepG2 ENCFF564AXY 491 bp overlap
ChIP HepG2 ENCFF564AXY 402 bp overlap
ZNF582 1 dataset
Motif DE_48h DE_48h-ZNF582_MA1983.2 19 bp overlap
ZNF614 1 dataset
ChIP HepG2 ENCFF677IUD 455 bp overlap
ZNF680 1 dataset
Motif DE_48h DE_48h-ZNF680_MA1729.2 11 bp overlap
ZNF766 2 datasets
Motif DE_48h DE_48h-ZNF766_MA2098.1 9 bp overlap
Motif DE_60h DE_60h-ZNF766_MA2098.1 9 bp overlap
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