chr1:27,592,703–27,593,619

chr1 : 27,592,703 – 27,593,619

916 bp 100 TFs 8 linked genes

This 916 bp open chromatin element is linked to 8 target genes and is bound by 100 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
AHDC1		10.9 kb	Distal	Multiome
WASF2		103.0 kb	Distal	Multiome
FAM76A		132.9 kb	Distal	Multiome
STX12		180.2 kb	Distal	Multiome
PPP1R8		237.8 kb	Distal	Multiome
SYTL1		251.0 kb	Distal	Multiome
TMEM222		270.8 kb	Distal	Multiome
THEMIS2		279.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

100 transcription factors

ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 93 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 242 bp overlap

ARID4B 1 dataset

ChIP WTC11 ENCFF441HDK 457 bp overlap

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 785 bp overlap

ChIP H1 ENCFF399KAM 706 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 729 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 257 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 699 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 578 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 712 bp overlap

BRD4 10 datasets

ChIP COLO-741 GSE73319.BRD4.COLO-741 220 bp overlap

ChIP Kelly_resistant GSE103030.BRD4.Kelly_resistant 221 bp overlap

ChIP Kelly_resistant_JQ1 GSE103030.BRD4.Kelly_resistant_JQ1 174 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 240 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 301 bp overlap

ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 204 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 487 bp overlap

ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 201 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 266 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 916 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 537 bp overlap

CHD2 3 datasets

ChIP H1 ENCFF991MKH 255 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 201 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 343 bp overlap

CHD4 2 datasets

ChIP RH5 GSE155861.CHD4.RH5 588 bp overlap

ChIP SCMC GSE155861.CHD4.SCMC 916 bp overlap

CHD7 2 datasets

ChIP hiPSC_AF22_abD3F5 GSE108506.CHD7.hiPSC_AF22_abD3F5 214 bp overlap

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 568 bp overlap

CREB1 2 datasets

ChIP GM23338 ENCFF432ZEW 184 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 140 bp overlap

CTCF 2 datasets

ChIP heart left ventricle ENCFF987PUT 371 bp overlap

ChIP heart_left-ventricle ENCSR791AYW.CTCF.heart_left-ventricle 245 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 175 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 273 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 307 bp overlap

ETS1 2 datasets

ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 93 bp overlap

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 196 bp overlap

ChIP HCT-116_A7A GSE152144.FOS.HCT-116_A7A 795 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 128 bp overlap

GABPA 1 dataset

ChIP WA01 ENCSR000BIW.GABPA.WA01 137 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 265 bp overlap

GATA6 2 datasets

ChIP DE_D2 S55-DE-d2-GATA6-exp2 247 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 343 bp overlap

GLIS2 1 dataset

ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 306 bp overlap

HDAC2 2 datasets

ChIP RH4_DMSO-6H GSE116344.HDAC2.RH4_DMSO-6H 494 bp overlap

ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 413 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 321 bp overlap

HEXIM1 2 datasets

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 426 bp overlap

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 196 bp overlap

HIC1 2 datasets

ChIP HEK293 ENCFF252CFL 233 bp overlap

ChIP HEK293 ENCSR803GYT.HIC1.HEK293 334 bp overlap

HNRNPH1 1 dataset

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 152 bp overlap

HNRNPL 5 datasets

ChIP Hep-G2 ENCSR315JJE.HNRNPL.Hep-G2 220 bp overlap

ChIP Hep-G2 GSE120104.HNRNPL.Hep-G2 220 bp overlap

ChIP HepG2 ENCFF671UYF 282 bp overlap

ChIP HepG2 ENCFF684GAM 282 bp overlap

ChIP K-562 ENCSR594BNR.HNRNPL.K-562 221 bp overlap

HNRNPLL 2 datasets

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 229 bp overlap

ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 134 bp overlap

JARID2 1 dataset

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 137 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 773 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 570 bp overlap

KLF17 1 dataset

ChIP HEK293 ENCSR065WUF.KLF17.HEK293 258 bp overlap

KLF5 2 datasets

ChIP HEK293_D418N GSE88976.KLF5.HEK293_D418N 191 bp overlap

ChIP HEK293_E419Q GSE88976.KLF5.HEK293_E419Q 202 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 100 bp overlap

KMT2A 2 datasets

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 325 bp overlap

ChIP RS4-11_DMSO-D3-180402 GSE127507.KMT2A.RS4-11_DMSO-D3-180402 100 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 361 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 169 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 350 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 170 bp overlap

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 111 bp overlap

ChIP RH4 GSE155861.MTA2.RH4 290 bp overlap

ChIP neural cell ENCFF623HQN 51 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 451 bp overlap

ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 65 bp overlap

MYOD1 4 datasets

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 886 bp overlap

ChIP RH4 GSE83726.MYOD1.RH4 254 bp overlap

ChIP myoblast GSE50413.MYOD1.myoblast 219 bp overlap

ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 169 bp overlap

MYOG 2 datasets

ChIP RH4_DMSO-6H GSE116344.MYOG.RH4_DMSO-6H 215 bp overlap

ChIP RH4_Entinostat-6H GSE116344.MYOG.RH4_Entinostat-6H 232 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 460 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 314 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 277 bp overlap

NELFE 1 dataset

ChIP K-562_HS GSE112379.NELFE.K-562_HS 211 bp overlap

NEUROG2 6 datasets

ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 282 bp overlap

ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 146 bp overlap

ChIP MRC-5_NFD_05DPT GSE75910.NEUROG2.MRC-5_NFD_05DPT 125 bp overlap

ChIP MRC-5_NFD_1DPT GSE75910.NEUROG2.MRC-5_NFD_1DPT 187 bp overlap

ChIP MRC-5_NFD_1DPT GSE75910.NEUROG2.MRC-5_NFD_1DPT 129 bp overlap

ChIP MRC-5_N_1DPT GSE75910.NEUROG2.MRC-5_N_1DPT 73 bp overlap

ChIP WTC11 ENCFF751ZTQ 265 bp overlap

ChIP EndoC-betaH2 GSE87530.PAX6.EndoC-betaH2 165 bp overlap

PCBP1 2 datasets

ChIP HepG2 ENCFF447SRJ 71 bp overlap

ChIP HepG2 ENCFF604TPT 71 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 191 bp overlap

PKNOX1 4 datasets

ChIP HEK293T ENCFF174WDB 181 bp overlap

ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 254 bp overlap

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 293 bp overlap

ChIP K562 ENCFF236IUS 206 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 284 bp overlap

POLR2A 3 datasets

ChIP adrenal gland ENCFF843OBJ 505 bp overlap

ChIP neural cell ENCFF604SPB 385 bp overlap

ChIP spleen ENCFF706IUS 223 bp overlap

POU5F1 3 datasets

ChIP BG03 GSE21614.POU5F1.BG03 202 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 916 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 447 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 916 bp overlap

RAD21 2 datasets

ChIP H1 ENCFF698EWO 241 bp overlap

ChIP RH4 GSE83726.RAD21.RH4 251 bp overlap

RBBP4 2 datasets

ChIP RH5 GSE155861.RBBP4.RH5 457 bp overlap

ChIP SCMC GSE155861.RBBP4.SCMC 916 bp overlap

RBBP5 2 datasets

ChIP WA01 ENCSR000AQC.RBBP5.WA01 135 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 566 bp overlap

RBFOX2 4 datasets

ChIP K-562 GSE120104.RBFOX2.K-562 407 bp overlap

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 407 bp overlap

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 275 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 275 bp overlap

ChIP neural ENCSR000BTV.REST.neural 252 bp overlap

ChIP K-562 ENCSR968GIB.RFX1.K-562 51 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 223 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 170 bp overlap

SIN3A 1 dataset

ChIP H1 ENCFF042ZSL 521 bp overlap

SIX2 2 datasets

ChIP HEK GSE73865.SIX2.HEK 202 bp overlap

ChIP kidney_fetal_17w GSE75948.SIX2.kidney_fetal_17w 172 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 470 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 409 bp overlap

SMAD3 1 dataset

ChIP BG03_DIFF_0H GSE36578.SMAD3.BG03_DIFF_0H 213 bp overlap

SMARCA4 5 datasets

ChIP NGP_ARID1A-het GSE134626.SMARCA4.NGP_ARID1A-het 94 bp overlap

ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 345 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 770 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 422 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 431 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 353 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 174 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 336 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 473 bp overlap

SOX2 2 datasets

ChIP HNSC GSE69479.SOX2.HNSC 399 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 330 bp overlap

ChIP H1 ENCFF263FUH 237 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 181 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 167 bp overlap

ChIP H1 ENCFF903ACN 264 bp overlap

ChIP WA01 ENCSR000BQG.SP2.WA01 143 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 323 bp overlap

SUPT5H 1 dataset

ChIP HeLa GSE125534.SUPT5H.HeLa 150 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 183 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 116 bp overlap

ChIP RCH-ACV GSE85988.TCF3.RCH-ACV 447 bp overlap

TEAD4 1 dataset

ChIP ESC S26-ESC-d0-TEAD4-exp1 295 bp overlap

TP63 2 datasets

ChIP breast-organoid GSE113909.TP63.breast-organoid 133 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 167 bp overlap

TRIM28 2 datasets

ChIP AF22 GSE84259.TRIM28.AF22 736 bp overlap

ChIP HEK293 ENCFF582MWI 563 bp overlap

TWIST1 4 datasets

ChIP BE2C GSE80151.TWIST1.BE2C 147 bp overlap

ChIP BE2C GSE80151.TWIST1.BE2C 115 bp overlap

ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 147 bp overlap

ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 115 bp overlap

ChIP K-562 GSE111469.USF2.K-562 205 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 111 bp overlap

ZBTB7A 1 dataset

ChIP Ishikawa ENCSR000BSZ.ZBTB7A.Ishikawa 535 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 127 bp overlap

ZFP14 1 dataset

ChIP HEK293T GSE78099.ZFP14.HEK293T 183 bp overlap

ZFP36 1 dataset

ChIP K-562 ENCSR776CYN.ZFP36.K-562 186 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 842 bp overlap

ChIP HEK293 ENCFF033NQQ 418 bp overlap

ZNF398 1 dataset

ChIP HEK293 ENCFF184XEW 457 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 240 bp overlap

ZNF479 1 dataset

ChIP HEK293T GSE78099.ZNF479.HEK293T 82 bp overlap

ZNF711 1 dataset

ChIP HEK293T GSE145160.ZNF711.HEK293T 649 bp overlap

ZNF714 1 dataset

ChIP HEK293T GSE78099.ZNF714.HEK293T 268 bp overlap

ZNF740 1 dataset

ChIP K562 ENCFF913GVQ 190 bp overlap

ZNF768 1 dataset

ChIP HepG2 ENCFF388QCK 260 bp overlap