ZNF768

zinc finger protein 768 | FLJ23436

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Biological processes 11 terms

DNA binding (GO:0003677)DNA-binding transcription factor activity, RNA polymerase II-specific (GO:0000981)RNA binding (GO:0003723)RNA polymerase II transcription regulatory region sequence-specific DNA binding (GO:0000977)chromosome (GO:0005694)nucleus (GO:0005634)nucleus (GO:0005634)protein binding (GO:0005515)regulation of transcription by RNA polymerase II (GO:0006357)sequence-specific double-stranded DNA binding (GO:1990837)transcription by RNA polymerase II (GO:0006366)

Expression (TPM)

TFs regulating ZNF768 0 TFs

Transcription factors with Perturb-seq knockdown data for ZNF768. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = ZNF768 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to ZNF768

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of ZNF768, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr16:30,334,526–30,335,777	191.2 kb	Distal (>10kb) Multiome	486
chr16:30,354,854–30,355,978	171.2 kb	Distal (>10kb) Multiome	1070
chr16:30,369,220–30,371,611	155.8 kb	Distal (>10kb) Multiome	818
chr16:30,377,495–30,379,532	148.2 kb	Distal (>10kb) Multiome	1025
chr16:30,394,422–30,396,098	131.4 kb	Distal (>10kb) Multiome	941
chr16:30,400,026–30,401,048	126.0 kb	Distal (>10kb) Multiome	839
chr16:30,406,974–30,408,429	119.1 kb	Distal (>10kb) Multiome	908
chr16:30,417,414–30,418,576	108.5 kb	Distal (>10kb) Multiome	543
chr16:30,429,571–30,430,773	96.4 kb	Distal (>10kb) Multiome	1060
chr16:30,445,340–30,446,062	80.7 kb	Distal (>10kb) Multiome	898
chr16:30,526,068–30,527,896	845 bp	At TSS Multiome	1004
chr16:30,534,370–30,535,460	8.3 kb	Proximal (<10kb) Multiome	957
chr16:30,535,765–30,536,130	9.2 kb	Proximal (<10kb)	553
chr16:30,557,913–30,558,847	31.9 kb	Distal (>10kb) Multiome	1025
chr16:30,571,001–30,572,505	45.5 kb	Distal (>10kb) Multiome	950
chr16:30,585,243–30,586,223	59.2 kb	Distal (>10kb) Multiome	588
chr16:30,609,586–30,610,748	83.9 kb	Distal (>10kb) Multiome	1030
chr16:30,634,070–30,634,986	107.8 kb	Distal (>10kb) Multiome	907
chr16:30,650,029–30,651,831	124.2 kb	Distal (>10kb) Multiome	992
chr16:30,657,638–30,659,894	131.7 kb	Distal (>10kb) Multiome	1053
chr16:30,677,814–30,678,622	151.6 kb	Distal (>10kb) Multiome	177
chr16:30,697,755–30,699,614	172.6 kb	Distal (>10kb) Multiome	1153
chr16:30,747,864–30,748,943	221.8 kb	Distal (>10kb) Multiome	824
chr16:30,761,380–30,762,606	235.7 kb	Distal (>10kb) Multiome	885
chr16:30,774,965–30,776,186	249.0 kb	Distal (>10kb) Multiome	1025
chr16:30,786,385–30,788,019	260.6 kb	Distal (>10kb) Multiome	885
chr16:30,805,468–30,806,187	279.1 kb	Distal (>10kb) Multiome	969
chr16:30,814,045–30,814,733	287.9 kb	Distal (>10kb) Multiome	995

Genome Browser

Genomic view of the ZNF768 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.