chr2 : 7,703,564 – 7,704,214

650 bp 105 TFs 2 linked genes

This 650 bp open chromatin element is linked to ENSG00000290092 and ID2 and is bound by 105 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000290092		172.9 kb	Distal	Multiome+HiCAR
ID2		975.1 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

105 transcription factors

ASCL1 3 datasets

ChIP NCI-H128 GSE69394.ASCL1.NCI-H128 120 bp overlap

ChIP NCI-H2107 GSE69394.ASCL1.NCI-H2107 109 bp overlap

ChIP SCLC_ASCLP GSE61197.ASCL1.SCLC_ASCLP 252 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 382 bp overlap

ASXL3 1 dataset

ChIP NCI-H1963_Ab2 GSE145028.ASXL3.NCI-H1963_Ab2 495 bp overlap

ATF2 1 dataset

ChIP WA01 ENCSR000BQU.ATF2.WA01 134 bp overlap

Ascl2 1 dataset

Motif ES_0h ES_0h-Ascl2_MA0816.1 10 bp overlap

BCL6 3 datasets

ChIP B-cell_GERMINAL_CENTER GSE68349.BCL6.B-cell_GERMINAL_CENTER 133 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 246 bp overlap

ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 84 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 210 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 308 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 614 bp overlap

BRD4 7 datasets

ChIP Mutu-1_vehicle GSE84213.BRD4.Mutu-1_vehicle 609 bp overlap

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 650 bp overlap

ChIP NCI-H1963_dBET6 GSE145028.BRD4.NCI-H1963_dBET6 407 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 532 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 635 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 416 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 145 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 258 bp overlap

CHD1 2 datasets

ChIP WA01 ENCSR000AQK.CHD1.WA01 352 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 159 bp overlap

CHD7 2 datasets

ChIP WA01 ENCSR000AVA.CHD7.WA01 484 bp overlap

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 271 bp overlap

CREB1 3 datasets

ChIP GM23338 ENCFF432ZEW 305 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 157 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 137 bp overlap

CREBBP 2 datasets

ChIP tonsil_GCBC_p5 GSE89688.CREBBP.tonsil_GCBC_p5 190 bp overlap

ChIP tonsil_GCBc_p4 GSE89688.CREBBP.tonsil_GCBc_p4 258 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 315 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF460KDD 251 bp overlap

ChIP BLaER1 ENCFF896HSY 218 bp overlap

E2F6 2 datasets

ChIP WA01 ENCSR000BSI.E2F6.WA01 325 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 90 bp overlap

EP300 1 dataset

ChIP WA01 ENCSR000BKK.EP300.WA01 217 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 265 bp overlap

ETS1 2 datasets

ChIP hESC ENCSR534VHI.ETS1.hESC 224 bp overlap

ChIP hESC ENCSR534VHI.ETS1.hESC 139 bp overlap

ETV1 2 datasets

ChIP GIST-T1 GSE106624.ETV1.GIST-T1 290 bp overlap

ChIP GIST-T1 GSE80443.ETV1.GIST-T1 144 bp overlap

ETV2::DRGX 1 dataset

Motif ES_0h ES_0h-ETV2DRGX_MA1940.2 12 bp overlap

ETV5::DRGX 1 dataset

Motif ES_0h ES_0h-ETV5DRGX_MA1944.2 12 bp overlap

ETV5::HOXA2 1 dataset

Motif ES_0h ES_0h-ETV5HOXA2_MA1948.2 12 bp overlap

FOXA1 1 dataset

Motif ES_0h ES_0h-FOXA1_MA0148.5 8 bp overlap

FOXB1 1 dataset

Motif ES_0h ES_0h-FOXB1_MA0845.1 11 bp overlap

FOXO1::FLI1 1 dataset

Motif ES_0h ES_0h-FOXO1FLI1_MA1956.2 13 bp overlap

Foxl2 1 dataset

Motif ES_0h ES_0h-Foxl2_MA1607.2 10 bp overlap

GABPA 1 dataset

ChIP Hep-G2 ENCSR000BJK.GABPA.Hep-G2 134 bp overlap

GFI1 1 dataset

Motif ES_0h ES_0h-GFI1_MA0038.3 11 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 393 bp overlap

HDAC2 2 datasets

ChIP WA01 ENCSR000AVB.HDAC2.WA01 189 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 127 bp overlap

HSF1 1 dataset

Motif ES_0h ES_0h-HSF1_MA0486.2 13 bp overlap

HSF2 1 dataset

Motif ES_0h ES_0h-HSF2_MA0770.1 13 bp overlap

HSF4 1 dataset

Motif ES_0h ES_0h-HSF4_MA0771.1 13 bp overlap

Hand1::Tcf3 1 dataset

Motif ES_0h ES_0h-Hand1Tcf3_MA0092.2 9 bp overlap

JUN 4 datasets

ChIP DE_D2 S02-DE-d2-JUN-exp1 489 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 510 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 284 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 638 bp overlap

JUND 1 dataset

ChIP WA01 ENCSR000BKP.JUND.WA01 119 bp overlap

KLF4 1 dataset

ChIP WA09 GSE105028.KLF4.WA09 481 bp overlap

LIN54 2 datasets

Motif ES_0h ES_0h-LIN54_MA0619.2 7 bp overlap

Lhx3 1 dataset

Motif ES_0h ES_0h-Lhx3_MA0135.2 12 bp overlap

MAX 4 datasets

ChIP H1 ENCFF914VQY 303 bp overlap

ChIP NCI-H128 GSE41105.MAX.NCI-H128 294 bp overlap

ChIP NCI-H128 GSE41105.MAX.NCI-H128 127 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 389 bp overlap

MEF2A 1 dataset

Motif ES_0h ES_0h-MEF2A_MA0052.5 10 bp overlap

MEF2B 2 datasets

Motif ES_0h ES_0h-MEF2B_MA0660.1 12 bp overlap

ChIP tonsil GSE110682.MEF2B.tonsil 396 bp overlap

MEF2C 1 dataset

Motif ES_0h ES_0h-MEF2C_MA0497.2 11 bp overlap

MEF2D 1 dataset

Motif ES_0h ES_0h-MEF2D_MA0773.1 12 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 576 bp overlap

MTA2 1 dataset

ChIP GM12878 ENCSR293QAR.MTA2.GM12878 134 bp overlap

NANOG 7 datasets

ChIP GM23338 ENCFF065NZG 245 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 492 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 615 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 154 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 650 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 578 bp overlap

ChIP hESC GSE18292.NANOG.hESC 101 bp overlap

NELFE 1 dataset

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 152 bp overlap

NFE2L1 1 dataset

ChIP WTC11 ENCFF644BPU 377 bp overlap

NFKB1 1 dataset

Motif ES_0h ES_0h-NFKB1_MA0105.4 13 bp overlap

NIPBL 4 datasets

ChIP WA09 GSE105028.NIPBL.WA09 358 bp overlap

ChIP WA09_heat-shock GSE105028.NIPBL.WA09_heat-shock 376 bp overlap

ChIP hESC GSE64758.NIPBL.hESC 238 bp overlap

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 229 bp overlap

NR3C1 1 dataset

ChIP A-549 ENCSR000BHF.NR3C1.A-549 134 bp overlap

PGR 1 dataset

Motif ES_0h ES_0h-PGR_MA2327.1 9 bp overlap

PLAG1 1 dataset

Motif ES_0h ES_0h-PLAG1_MA0163.1 14 bp overlap

POLR2A 1 dataset

ChIP H1 ENCFF833NJP 392 bp overlap

POU5F1 7 datasets

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 650 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 246 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 296 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 456 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 199 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 369 bp overlap

PRDM1 1 dataset

ChIP fetal_testis GSE100639.PRDM1.fetal_testis 163 bp overlap

PRDM14 2 datasets

ChIP NCCIT GSE71675.PRDM14.NCCIT 252 bp overlap

ChIP hESC GSE22767.PRDM14.hESC 492 bp overlap

PRDM15 1 dataset

ChIP WTC11 ENCFF108TMF 401 bp overlap

Plagl1 1 dataset

Motif ES_0h ES_0h-Plagl1_MA1615.2 8 bp overlap

RAD21 2 datasets

ChIP WA09 GSE105028.RAD21.WA09 494 bp overlap

ChIP WA09_heat-shock GSE105028.RAD21.WA09_heat-shock 289 bp overlap

RELA 1 dataset

ChIP SGBS_TNF GSE64233.RELA.SGBS_TNF 77 bp overlap

RNF2 2 datasets

ChIP WA09 GSE105028.RNF2.WA09 359 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 317 bp overlap

RREB1 1 dataset

Motif ES_0h ES_0h-RREB1_MA0073.2 19 bp overlap

RXRA 1 dataset

ChIP WA01 ENCSR000BJW.RXRA.WA01 145 bp overlap

SALL3 1 dataset

ChIP hiPSC GSE104863.SALL3.hiPSC 481 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 439 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 592 bp overlap

SMAD2_3 1 dataset

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 350 bp overlap

SMAD3 2 datasets

ChIP BG03 GSE21614.SMAD3.BG03 517 bp overlap

ChIP hESC GSE75297.SMAD3.hESC 325 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 182 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 613 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 63 bp overlap

SMARCC1 4 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 632 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 228 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 59 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 378 bp overlap

SOX10 1 dataset

Motif ES_0h ES_0h-SOX10_MA0442.3 6 bp overlap

SOX2 3 datasets

ChIP HNSC GSE69479.SOX2.HNSC 301 bp overlap

ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 389 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 441 bp overlap

SP1 3 datasets

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 282 bp overlap

ChIP WTC11 ENCFF688PEU 501 bp overlap

SREBF1 1 dataset

Motif ES_0h ES_0h-SREBF1_MA0829.3 10 bp overlap

STAT1 1 dataset

Motif ES_0h ES_0h-STAT1_MA0137.4 9 bp overlap

TAF1 1 dataset

ChIP WA01 ENCSR000BHO.TAF1.WA01 169 bp overlap

TBP 1 dataset

ChIP hESC GSE122298.TBP.hESC 166 bp overlap

TCF12 3 datasets

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 257 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 115 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 650 bp overlap

TEAD1 1 dataset

Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap

TEAD4 3 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 352 bp overlap

ChIP H1 ENCFF778PAX 245 bp overlap

ChIP hESC GSE99202.TEAD4.hESC 417 bp overlap

TFAP4::FLI1 1 dataset

Motif ES_0h ES_0h-TFAP4FLI1_MA1967.2 14 bp overlap

USF1 2 datasets

ChIP H1 ENCFF090WVU 177 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 306 bp overlap

YY1 2 datasets

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 326 bp overlap

ZBTB21 1 dataset

ChIP WTC11 ENCFF677ZYY 361 bp overlap

ZBTB26 1 dataset

Motif ES_0h ES_0h-ZBTB26_MA1579.2 8 bp overlap

ZBTB43 1 dataset

ChIP WTC11 ENCFF058JUB 392 bp overlap

ZIC1 1 dataset

Motif ES_0h ES_0h-ZIC1_MA0696.1 14 bp overlap

ZNF143 1 dataset

ChIP WA09_heat-shock GSE105028.ZNF143.WA09_heat-shock 174 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 399 bp overlap

ZNF257 1 dataset

Motif ES_0h ES_0h-ZNF257_MA1710.2 10 bp overlap

ZNF263 2 datasets

ChIP WTC11 ENCFF893RTM 318 bp overlap

ChIP WTC11 ENCFF893RTM 437 bp overlap

ZNF317 1 dataset

Motif ES_0h ES_0h-ZNF317_MA1593.2 8 bp overlap

ZNF331 1 dataset

Motif ES_0h ES_0h-ZNF331_MA1726.2 10 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 317 bp overlap

ZNF454 1 dataset

Motif ES_0h ES_0h-ZNF454_MA1712.2 17 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 229 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 260 bp overlap

ZNF530 1 dataset

Motif ES_0h ES_0h-ZNF530_MA1981.2 14 bp overlap

ZNF667 1 dataset

Motif ES_0h ES_0h-ZNF667_MA1984.2 11 bp overlap

ZNF768 1 dataset

Motif ES_0h ES_0h-ZNF768_MA1731.2 9 bp overlap

ZNF85 1 dataset

Motif ES_0h ES_0h-ZNF85_MA1720.2 12 bp overlap

Zic2 1 dataset

Motif ES_0h ES_0h-Zic2_MA1629.2 9 bp overlap