chr15:64,915,576–64,916,281

chr15 : 64,915,576 – 64,916,281

705 bp 115 TFs 9 linked genes

This 705 bp open chromatin element is linked to 9 target genes and is bound by 115 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ANKDD1A		3.7 kb	Proximal	Proximity
SPG21		74.0 kb	Distal	Multiome
PIF1		90.3 kb	Distal	Multiome
MTFMT		113.7 kb	Distal	Multiome
RBPMS2		140.3 kb	Distal	Multiome
UBAP1L		185.7 kb	Distal	Multiome
OAZ2		212.7 kb	Distal	Multiome
PDCD7		217.9 kb	Distal	Multiome
CLPX		269.4 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

115 transcription factors

ARNT::HIF1A 1 dataset

Motif DE_72h DE_72h-ARNTHIF1A_MA0259.2 5 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 412 bp overlap

Motif DE_72h DE_72h-Arnt_MA0004.1 6 bp overlap

BCL6 3 datasets

Motif DE_72h DE_72h-BCL6_MA0463.3 13 bp overlap

ChIP HepG2 ENCFF423EJH 179 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 286 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 201 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 310 bp overlap

CEBPA 1 dataset

ChIP HepG2 ENCFF175DFS 305 bp overlap

CEBPB 1 dataset

ChIP Hep-G2 ENCSR000EEX.CEBPB.Hep-G2 106 bp overlap

CREB1 2 datasets

ChIP H1 ENCFF955PMP 321 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 176 bp overlap

Cebpa 4 datasets

ChIP BLaER1 ENCFF031ISE 491 bp overlap

ChIP BLaER1 ENCFF274GAT 462 bp overlap

ChIP BLaER1 ENCFF335XTP 251 bp overlap

ChIP BLaER1 ENCFF364PUR 218 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 308 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 687 bp overlap

ChIP Hep-G2 ENCSR026GSW.EGR1.Hep-G2 370 bp overlap

EPAS1 1 dataset

Motif DE_72h DE_72h-EPAS1_MA2325.1 9 bp overlap

ERF::FIGLA 2 datasets

Motif DE_72h DE_72h-ERFFIGLA_MA1934.2 13 bp overlap

Motif DE_72h DE_72h-ERFFIGLA_MA1934.2 13 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 255 bp overlap

ESRRA 1 dataset

ChIP WTC11 ENCFF591YCA 363 bp overlap

ETV2::FIGLA 2 datasets

Motif DE_72h DE_72h-ETV2FIGLA_MA1941.2 13 bp overlap

Motif DE_72h DE_72h-ETV2FIGLA_MA1941.2 13 bp overlap

ETV5::FIGLA 1 dataset

Motif DE_72h DE_72h-ETV5FIGLA_MA1945.2 14 bp overlap

ETV5::FOXI1 1 dataset

Motif DE_72h DE_72h-ETV5FOXI1_MA1946.2 12 bp overlap

FIGLA 1 dataset

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FOSL2 1 dataset

ChIP HepG2 ENCFF548CXY 357 bp overlap

FOXA1 4 datasets

ChIP HepG2 ENCFF207NVJ 281 bp overlap

ChIP HepG2 ENCFF361KNY 285 bp overlap

ChIP HepG2 ENCFF740VZW 285 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 225 bp overlap

FOXA2 5 datasets

ChIP Caco-2 GSE66218.FOXA2.Caco-2 160 bp overlap

ChIP DE DE-FOXA2-1 558 bp overlap

ChIP DE DE-FOXA2-2 597 bp overlap

ChIP HepG2 ENCFF570ABM 405 bp overlap

ChIP HepG2 ENCFF894AYY 381 bp overlap

FOXA3 1 dataset

ChIP HepG2 ENCFF005KGL 361 bp overlap

GATA2 1 dataset

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 243 bp overlap

GATA4 4 datasets

ChIP DE DE-GATA4-1 437 bp overlap

ChIP DE DE-GATA4-2 422 bp overlap

ChIP foregut GSE117136.GATA4.foregut 355 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 310 bp overlap

GATA6 4 datasets

ChIP DE DE-GATA6-1 343 bp overlap

ChIP DE DE-GATA6-2 561 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 324 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 265 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 280 bp overlap

HDAC2 1 dataset

ChIP Hep-G2 ENCSR000BMC.HDAC2.Hep-G2 142 bp overlap

HIF1A 1 dataset

Motif DE_72h DE_72h-HIF1A_MA1106.2 6 bp overlap

HIF3A 1 dataset

ChIP Hep-3B2-1-7 GSE129491.HIF3A.Hep-3B2-1-7 624 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 488 bp overlap

HNF4A 4 datasets

ChIP Hep-G2 ENCSR000BLF.HNF4A.Hep-G2 137 bp overlap

ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 260 bp overlap

ChIP Hep-G2 ERP000209.HNF4A.Hep-G2 224 bp overlap

ChIP HepG2 ENCFF146SSF 300 bp overlap

HNF4G 1 dataset

ChIP Hep-G2 ENCSR000BNJ.HNF4G.Hep-G2 140 bp overlap

HOXB13 1 dataset

ChIP prostate_P1 GSE130408.HOXB13.prostate_P1 138 bp overlap

HOXB4 1 dataset

Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap

HOXC4 1 dataset

Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap

HOXD4 1 dataset

Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap

JARID2 1 dataset

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 177 bp overlap

KDM1A 1 dataset

ChIP NCI-H526_DMSO GSE66297.KDM1A.NCI-H526_DMSO 280 bp overlap

L3MBTL2 1 dataset

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 240 bp overlap

Motif DE_72h DE_72h-MAX_MA0058.4 6 bp overlap

ChIP H1 ENCFF601FOM 325 bp overlap

ChIP H1 ENCFF914VQY 343 bp overlap

ChIP Hep-G2 ENCSR168DYA.MAX.Hep-G2 431 bp overlap

ChIP Hep-G2 ENCSR000BTM.MAX.Hep-G2 255 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 116 bp overlap

ChIP K562 ENCFF524IJO 397 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 319 bp overlap

ChIP WTC11 ENCFF223QFY 537 bp overlap

MAX::MYC 1 dataset

Motif DE_72h DE_72h-MAXMYC_MA0059.2 10 bp overlap

Motif DE_72h DE_72h-MNT_MA0825.2 6 bp overlap

ChIP Hep-G2 ENCSR261EDU.MNT.Hep-G2 223 bp overlap

ChIP HepG2 ENCFF701PYP 385 bp overlap

Motif DE_72h DE_72h-MYC_MA0147.4 8 bp overlap

ChIP H1 ENCFF794ZJT 265 bp overlap

Motif DE_72h DE_72h-MYCN_MA0104.5 8 bp overlap

Mlxip 1 dataset

Motif DE_72h DE_72h-Mlxip_MA0622.2 6 bp overlap

Motif DE_72h DE_72h-NFYA_MA0060.4 8 bp overlap

Motif DE_72h DE_72h-NFYC_MA1644.2 7 bp overlap

NHLH2 1 dataset

Motif DE_72h DE_72h-NHLH2_MA1529.2 16 bp overlap

NKX2-1 1 dataset

ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 410 bp overlap

NR2C1 2 datasets

ChIP K-562 ENCSR742IDN.NR2C1.K-562 266 bp overlap

ChIP K562 ENCFF239KMA 349 bp overlap

NR2C2 4 datasets

ChIP Hep-G2 ENCSR559ZKI.NR2C2.Hep-G2 318 bp overlap

ChIP Hep-G2 ENCSR000EVS.NR2C2.Hep-G2 134 bp overlap

ChIP HepG2 ENCFF944PRH 172 bp overlap

ChIP K562 ENCFF750AXF 595 bp overlap

NR2F1 3 datasets

ChIP GM12878 ENCSR514VYD.NR2F1.GM12878 184 bp overlap

ChIP HepG2 ENCFF953UJL 301 bp overlap

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 417 bp overlap

NR2F2 3 datasets

ChIP Hep-G2 ENCSR000BVM.NR2F2.Hep-G2 181 bp overlap

ChIP K-562 ENCSR000BRS.NR2F2.K-562 155 bp overlap

ChIP K-562 ENCSR000BRS.NR2F2.K-562 148 bp overlap

NR2F6 5 datasets

ChIP Hep-G2 ENCSR518WPL.NR2F6.Hep-G2 380 bp overlap

ChIP HepG2 ENCFF429VKC 151 bp overlap

ChIP HepG2 ENCFF514UJI 320 bp overlap

ChIP K-562 ENCSR707QWA.NR2F6.K-562 336 bp overlap

ChIP K562 ENCFF674RQA 331 bp overlap

NR5A1 2 datasets

ChIP Hep-G2 ENCSR310OZS.NR5A1.Hep-G2 243 bp overlap

ChIP HepG2 ENCFF970YZO 377 bp overlap

Npas2 1 dataset

Motif DE_72h DE_72h-Npas2_MA0626.2 8 bp overlap

Nr2F6 1 dataset

Motif DE_72h DE_72h-Nr2F6_MA0728.1 15 bp overlap

POU2F3 1 dataset

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 317 bp overlap

POU5F1 3 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 550 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 291 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 414 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 496 bp overlap

POU6F1 1 dataset

Motif DE_72h DE_72h-POU6F1_MA1549.2 7 bp overlap

POU6F2 1 dataset

Motif DE_72h DE_72h-POU6F2_MA0793.2 9 bp overlap

PROX1 1 dataset

ChIP HepG2 ENCFF016ZJS 351 bp overlap

ChIP HepG2 ENCFF582XUA 357 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 135 bp overlap

Motif DE_72h DE_72h-REST_MA0138.3 20 bp overlap

RUNX1-RUNX1T1 1 dataset

ChIP AML GSE131939.RUNX1-RUNX1T1.AML 132 bp overlap

RUNX2 2 datasets

ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 303 bp overlap

ChIP PER-117 GSE151819.RUNX2.PER-117 126 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 352 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 265 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 484 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 472 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 317 bp overlap

SMAD3 1 dataset

ChIP WTC11 ENCFF815YYQ 357 bp overlap

SMAD4 2 datasets

ChIP HepG2 ENCFF615GTE 337 bp overlap

ChIP endoderm GSE29422.SMAD4.endoderm 189 bp overlap

SMARCA4 1 dataset

ChIP NSC GSE125033.SMARCA4.NSC 389 bp overlap

SOHLH2 1 dataset

Motif DE_72h DE_72h-SOHLH2_MA1560.2 8 bp overlap

SOX12 1 dataset

Motif DE_72h DE_72h-SOX12_MA1561.2 10 bp overlap

SOX13 1 dataset

ChIP HepG2 ENCFF062VSQ 357 bp overlap

SOX14 1 dataset

Motif DE_72h DE_72h-SOX14_MA1562.2 9 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 349 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 604 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 316 bp overlap

ChIP HepG2 ENCFF470KZD 405 bp overlap

SOX6 2 datasets

ChIP Hep-G2 ENCSR766TSU.SOX6.Hep-G2 419 bp overlap

ChIP HepG2 ENCFF767OCK 494 bp overlap

Motif DE_72h DE_72h-SOX8_MA0868.3 7 bp overlap

Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Sox11 1 dataset

Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap

Sox17 1 dataset

Motif DE_72h DE_72h-Sox17_MA0078.3 10 bp overlap

Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

Motif DE_72h DE_72h-Sox7_MA2095.1 10 bp overlap

Stat4 1 dataset

Motif DE_72h DE_72h-Stat4_MA0518.2 10 bp overlap

Motif DE_72h DE_72h-TBX2_MA0688.2 9 bp overlap

Motif DE_72h DE_72h-TCF3_MA0522.4 7 bp overlap

Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 227 bp overlap

TFAP4::ETV1 1 dataset

Motif DE_72h DE_72h-TFAP4ETV1_MA1966.2 13 bp overlap

ChIP WTC11 ENCFF359JCU 537 bp overlap

USF1 2 datasets

ChIP H1 ENCFF090WVU 241 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 177 bp overlap

ZBTB21 1 dataset

ChIP WTC11 ENCFF677ZYY 401 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ZNF175 1 dataset

ChIP Hep-G2 ENCSR014RHK.ZNF175.Hep-G2 128 bp overlap

ZNF217 1 dataset

ChIP Hep-G2 ENCSR055FQB.ZNF217.Hep-G2 211 bp overlap

ZNF219 1 dataset

ChIP HepG2 ENCFF266JIR 359 bp overlap

ZNF263 8 datasets

Motif DE_72h DE_72h-ZNF263_MA0528.3 7 bp overlap

ChIP HEK293 ENCFF336CWQ 369 bp overlap

ChIP HEK293 ENCFF336CWQ 579 bp overlap

ChIP Hep-G2 ENCSR313MMD.ZNF263.Hep-G2 571 bp overlap

ChIP HepG2 ENCFF626SSV 300 bp overlap

ChIP K-562 ENCSR000EWN.ZNF263.K-562 319 bp overlap

ChIP K562 ENCFF640RNA 379 bp overlap

ChIP WTC11 ENCFF893RTM 425 bp overlap

ZNF341 1 dataset

ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 108 bp overlap

ZNF454 1 dataset

Motif DE_72h DE_72h-ZNF454_MA1712.2 17 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 146 bp overlap

ZNF550 1 dataset

ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 202 bp overlap

ZNF766 1 dataset

Motif DE_72h DE_72h-ZNF766_MA2098.1 9 bp overlap

ZNF768 1 dataset

Motif DE_72h DE_72h-ZNF768_MA1731.2 9 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 261 bp overlap