chr15 : 41,567,657 – 41,568,120

463 bp 98 TFs 1 linked gene

This 463 bp open chromatin element is linked to TYRO3 and is bound by 98 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
TYRO3		8.4 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

98 transcription factors

ARID4A 1 dataset

ChIP Hep-G2 ENCSR386UBO.ARID4A.Hep-G2 154 bp overlap

ASH2L 2 datasets

ChIP Hep-G2 ENCSR508LMH.ASH2L.Hep-G2 419 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 374 bp overlap

BCOR 1 dataset

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 107 bp overlap

BRD4 2 datasets

ChIP K-562_dilution-6-100 GSE140325.BRD4.K-562_dilution-6-100 115 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 132 bp overlap

CHD1 3 datasets

ChIP H1 ENCFF998XEK 303 bp overlap

ChIP H1 ENCFF998XEK 103 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 57 bp overlap

CHD2 1 dataset

ChIP H1 ENCFF991MKH 250 bp overlap

CHD4 1 dataset

ChIP 501-mel GSE134848.CHD4.501-mel 261 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 193 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 99 bp overlap

DMAP1 1 dataset

ChIP Hep-G2 ENCSR670YPQ.DMAP1.Hep-G2 123 bp overlap

EGR1 1 dataset

ChIP Hep-G2 ENCSR026GSW.EGR1.Hep-G2 91 bp overlap

ELF1 1 dataset

ChIP Hep-G2 ENCSR321VGW.ELF1.Hep-G2 137 bp overlap

EP300 5 datasets

ChIP H1 ENCFF927IYK 242 bp overlap

ChIP H1 ENCFF937OPV 205 bp overlap

ChIP Hep-G2 ENCSR000BLW.EP300.Hep-G2 109 bp overlap

ChIP HepG2 ENCFF354ACD 177 bp overlap

ChIP WA01 ENCSR000AUQ.EP300.WA01 170 bp overlap

ETS1 1 dataset

ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 107 bp overlap

FIP1L1 1 dataset

ChIP Hep-G2 ENCSR313VZG.FIP1L1.Hep-G2 250 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 463 bp overlap

ChIP DE DE-FOXA2-2 463 bp overlap

FOXP1 1 dataset

ChIP Hep-G2 ENCSR369YUK.FOXP1.Hep-G2 137 bp overlap

FOXP4 1 dataset

ChIP Hep-G2 ENCSR232LLP.FOXP4.Hep-G2 178 bp overlap

GATA1 2 datasets

ChIP K-562 GSE107726.GATA1.K-562 224 bp overlap

ChIP K-562 ENCSR000EFT.GATA1.K-562 121 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 463 bp overlap

ChIP DE DE-GATA4-2 463 bp overlap

ChIP foregut GSE117136.GATA4.foregut 381 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 399 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 263 bp overlap

GATA6 13 datasets

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 109 bp overlap

ChIP DE DE-GATA6-1 453 bp overlap

ChIP DE DE-GATA6-2 463 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 204 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 331 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 370 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 422 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 406 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 463 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 366 bp overlap

ChIP foregut GSE117136.GATA6.foregut 351 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 349 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 224 bp overlap

GFI1B 1 dataset

ChIP K-562 ENCSR509GDT.GFI1B.K-562 166 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 184 bp overlap

HBP1 1 dataset

ChIP Hep-G2 ENCSR616WEG.HBP1.Hep-G2 124 bp overlap

HDAC1 1 dataset

ChIP Hep-G2 ENCSR750OWO.HDAC1.Hep-G2 112 bp overlap

HDAC2 2 datasets

ChIP K-562 ENCSR893WSB.HDAC2.K-562 261 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 139 bp overlap

HMGXB4 1 dataset

ChIP Hep-G2 ENCSR174GOO.HMGXB4.Hep-G2 137 bp overlap

HNF4A 3 datasets

ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 119 bp overlap

ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 231 bp overlap

ChIP Hep-G2 ENCSR000BLF.HNF4A.Hep-G2 130 bp overlap

HNF4G 1 dataset

ChIP Hep-G2 ENCSR000BNJ.HNF4G.Hep-G2 101 bp overlap

HNRNPL 1 dataset

ChIP Hep-G2 ENCSR315JJE.HNRNPL.Hep-G2 170 bp overlap

HOXA3 1 dataset

ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 203 bp overlap

IKZF1 1 dataset

ChIP K-562 ENCSR395HWC.IKZF1.K-562 256 bp overlap

JUND 1 dataset

ChIP Hep-G2 ENCSR000BGK.JUND.Hep-G2 76 bp overlap

KDM1A 1 dataset

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 333 bp overlap

KLF6 1 dataset

ChIP Hep-G2 ENCSR757EKM.KLF6.Hep-G2 93 bp overlap

KLF9 1 dataset

ChIP GBM1A GSE62211.KLF9.GBM1A 144 bp overlap

KMT2A 1 dataset

ChIP Hep-G2 ENCSR692GFR.KMT2A.Hep-G2 150 bp overlap

MAX 2 datasets

ChIP Hep-G2 ENCSR000BTM.MAX.Hep-G2 143 bp overlap

ChIP Hep-G2 ENCSR168DYA.MAX.Hep-G2 90 bp overlap

MCRS1 2 datasets

ChIP Hep-G2 GSE107730.MCRS1.Hep-G2 92 bp overlap

ChIP Hep-G2 GSE97411.MCRS1.Hep-G2 92 bp overlap

MED1 3 datasets

ChIP Hep-G2 ENCSR959XNY.MED1.Hep-G2 207 bp overlap

ChIP SGBS GSE64233.MED1.SGBS 136 bp overlap

ChIP VCaP_R1881 GSE148358.MED1.VCaP_R1881 240 bp overlap

MNX1 1 dataset

ChIP Hep-G2 ENCSR108MKR.MNX1.Hep-G2 164 bp overlap

MXD4 1 dataset

ChIP Hep-G2 ENCSR441KFW.MXD4.Hep-G2 149 bp overlap

MYBL2 1 dataset

ChIP Hep-G2 ENCSR581KCO.MYBL2.Hep-G2 120 bp overlap

MYNN 1 dataset

ChIP Hep-G2 ENCSR398TMP.MYNN.Hep-G2 220 bp overlap

NELFE 1 dataset

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 72 bp overlap

NEUROD1 1 dataset

ChIP D283-Med GSE92582.NEUROD1.D283-Med 179 bp overlap

NFIC 1 dataset

ChIP HepG2 ENCFF169TKU 223 bp overlap

NFKBIZ 1 dataset

ChIP Hep-G2 ENCSR235OVI.NFKBIZ.Hep-G2 196 bp overlap

NR3C1 2 datasets

ChIP A-549 ENCSR000BHF.NR3C1.A-549 136 bp overlap

ChIP A-549 ENCSR000BJR.NR3C1.A-549 108 bp overlap

NSD2 1 dataset

ChIP K-562 ENCSR000AVE.NSD2.K-562 166 bp overlap

PAXIP1 1 dataset

ChIP Hep-G2 ENCSR530ARJ.PAXIP1.Hep-G2 257 bp overlap

PHF5A 1 dataset

ChIP Hep-G2 ENCSR191TLD.PHF5A.Hep-G2 157 bp overlap

PHF8 2 datasets

ChIP H1 ENCFF427UFV 227 bp overlap

ChIP Hep-G2 ENCSR604VAE.PHF8.Hep-G2 161 bp overlap

POLR2A 3 datasets

ChIP H1 ENCFF566JSR 168 bp overlap

ChIP H1 ENCFF833NJP 191 bp overlap

ChIP HepG2 ENCFF350RIU 262 bp overlap

PPARG 2 datasets

ChIP Hep-G2 ENCSR130VQL.PPARG.Hep-G2 199 bp overlap

ChIP HepG2 ENCFF329FBJ 101 bp overlap

PRPF4 2 datasets

ChIP Hep-G2 ENCSR243LNQ.PRPF4.Hep-G2 301 bp overlap

ChIP Hep-G2 GSE120104.PRPF4.Hep-G2 271 bp overlap

PRRX2 1 dataset

ChIP WTC11 ENCFF107JGJ 226 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 194 bp overlap

RBFOX2 1 dataset

ChIP HepG2 ENCFF554DMZ 240 bp overlap

RELA 1 dataset

ChIP 786-O GSE86092.RELA.786-O 206 bp overlap

RFX1 8 datasets

ChIP K-562 ENCSR968GIB.RFX1.K-562 378 bp overlap

ChIP K-562 ENCSR041AXL.RFX1.K-562 355 bp overlap

ChIP K562 ENCFF421AVO 377 bp overlap

ChIP K562 ENCFF809XVG 335 bp overlap

ChIP MCF-7 ENCFF782EZS 321 bp overlap

ChIP MCF-7 ENCFF973QAD 197 bp overlap

ChIP MCF-7 ENCSR788XNX.RFX1.MCF-7 323 bp overlap

ChIP MCF-7 ENCSR066TET.RFX1.MCF-7 274 bp overlap

RFX3 1 dataset

ChIP Hep-G2 ENCSR633OVO.RFX3.Hep-G2 174 bp overlap

RREB1 1 dataset

ChIP HepG2 ENCFF986CSN 233 bp overlap

RXRA 2 datasets

ChIP Hep-G2 ENCSR000BHU.RXRA.Hep-G2 113 bp overlap

ChIP HepG2 ENCFF204YVO 178 bp overlap

SIN3A 1 dataset

ChIP H1 ENCFF042ZSL 367 bp overlap

SIX1 1 dataset

ChIP Hep-G2 ENCSR561BQM.SIX1.Hep-G2 104 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 240 bp overlap

SMARCA4 1 dataset

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 236 bp overlap

SMARCB1 1 dataset

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 92 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 195 bp overlap

SP1 4 datasets

ChIP H1 ENCFF263FUH 260 bp overlap

ChIP Hep-G2 ENCSR000BJX.SP1.Hep-G2 120 bp overlap

ChIP HepG2 ENCFF123KAM 215 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 239 bp overlap

SP5 1 dataset

ChIP Hep-G2 ENCSR019NPF.SP5.Hep-G2 157 bp overlap

TAF1 1 dataset

ChIP WA01 ENCSR000BHO.TAF1.WA01 139 bp overlap

TBL1XR1 1 dataset

ChIP Hep-G2 ENCSR101FJS.TBL1XR1.Hep-G2 145 bp overlap

TBX5 2 datasets

ChIP cardiomyocyte GSE85628.TBX5.cardiomyocyte 308 bp overlap

ChIP cardiomyocyte_1 GSE85628.TBX5.cardiomyocyte_1 308 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 273 bp overlap

ChIP WA09 GSE105081.TFAP2C.WA09 141 bp overlap

TFE3 1 dataset

ChIP Hep-G2 ENCSR589SNT.TFE3.Hep-G2 117 bp overlap

U2AF1 1 dataset

ChIP Hep-G2 ENCSR868JLS.U2AF1.Hep-G2 229 bp overlap

YY1 1 dataset

ChIP Huh-7 GSE97411.YY1.Huh-7 267 bp overlap

ZBTB7A 2 datasets

ChIP Hep-G2 ENCSR000BQA.ZBTB7A.Hep-G2 193 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 113 bp overlap

ZBTB7B 1 dataset

ChIP Hep-G2 ENCSR322ULL.ZBTB7B.Hep-G2 102 bp overlap

ZEB2 1 dataset

ChIP K-562 ENCSR004GKA.ZEB2.K-562 253 bp overlap

ZGPAT 1 dataset

ChIP Hep-G2 ENCSR704IGU.ZGPAT.Hep-G2 144 bp overlap

ZKSCAN1 1 dataset

ChIP Hep-G2 ENCSR157CAU.ZKSCAN1.Hep-G2 132 bp overlap

ZNF143 1 dataset

ChIP Hep-G2 ENCSR080UEM.ZNF143.Hep-G2 143 bp overlap

ZNF148 1 dataset

ChIP K-562 GSE121133.ZNF148.K-562 185 bp overlap

ZNF217 1 dataset

ChIP Hep-G2 ENCSR055FQB.ZNF217.Hep-G2 169 bp overlap

ZNF274 1 dataset

ChIP Hep-G2 ENCSR871VNN.ZNF274.Hep-G2 241 bp overlap

ZNF281 1 dataset

ChIP HepG2 ENCFF585QNU 159 bp overlap

ZNF341 2 datasets

ChIP HEK293 ENCFF944VMC 345 bp overlap

ChIP HEK293 ENCSR185FOY.ZNF341.HEK293 341 bp overlap

ZNF395 2 datasets

ChIP K562 ENCFF464EIT 463 bp overlap

ChIP K562 ENCFF464EIT 110 bp overlap

ZNF407 1 dataset

ChIP Hep-G2 ENCSR005WGY.ZNF407.Hep-G2 207 bp overlap

ZNF416 1 dataset

ChIP WTC11 ENCFF407TAZ 115 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 186 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 134 bp overlap

ZNF543 1 dataset

ChIP HepG2 ENCFF864SAR 381 bp overlap

ZNF816 1 dataset

ChIP HepG2 ENCFF294VPD 255 bp overlap

ZNF883 1 dataset

ChIP Hep-G2 ENCSR882YYL.ZNF883.Hep-G2 206 bp overlap