chr6 : 111,661,571 – 111,662,099
528 bp 114 TFs 5 linked genes
This 528 bp open chromatin element is linked to 5 target genes and is bound by 114 transcription factors.
Linked Genes
5 genes
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
TRAF3IP2 56.0 kb Distal Multiome
REV3L 178.1 kb Distal Multiome
TRAF3IP2-AS1 178.3 kb Distal Multiome
FYN 211.6 kb Distal Multiome
MFSD4B 402.5 kb Distal Multiome+HiCAR
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr6:111,656,571 – 111,667,099
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
114 transcription factors
Source
Cell type
AGO1 2 datasets
ChIP Hep-G2 GSE120104.AGO1.Hep-G2 379 bp overlap
ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 183 bp overlap
AR 4 datasets
ChIP LNCaP-95_NT GSE125552.AR.LNCaP-95_NT 318 bp overlap
ChIP MDA-MB-453 ERP003503.AR.MDA-MB-453 156 bp overlap
ChIP VCaP_DHT24H_SHFOXP1 GSE58428.AR.VCaP_DHT24H_SHFOXP1 102 bp overlap
ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 240 bp overlap
ASCL1 3 datasets
ChIP NCI-H2107 GSE69394.ASCL1.NCI-H2107 161 bp overlap
ChIP SCLC_ASCLP GSE61197.ASCL1.SCLC_ASCLP 160 bp overlap
ChIP SCLC_ASCLP GSE61197.ASCL1.SCLC_ASCLP 119 bp overlap
ASH2L 3 datasets
ChIP H1 ENCFF399KAM 316 bp overlap
ChIP H1 ENCFF399KAM 371 bp overlap
ChIP WA01 ENCSR850KIP.ASH2L.WA01 528 bp overlap
Ascl2 1 dataset
Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap
BCOR 4 datasets
ChIP WA01 GSE104690.BCOR.WA01 249 bp overlap
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 299 bp overlap
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 150 bp overlap
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 528 bp overlap
BHLHE22 1 dataset
Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap
BHLHE40 1 dataset
ChIP K562 ENCFF923NJI 206 bp overlap
BRD1 1 dataset
ChIP HUES-64 GSE104059.BRD1.HUES-64 384 bp overlap
BRD4 11 datasets
ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 216 bp overlap
ChIP LNCaP-C4-2_F133V GSE88871.BRD4.LNCaP-C4-2_F133V 194 bp overlap
ChIP LNCaP-C4-2_OE GSE88871.BRD4.LNCaP-C4-2_OE 118 bp overlap
ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 259 bp overlap
ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 397 bp overlap
ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 274 bp overlap
ChIP NCI-H2171_DMSO GSE49224.BRD4.NCI-H2171_DMSO 165 bp overlap
ChIP NCI-H2171_DMSO GSE49224.BRD4.NCI-H2171_DMSO 130 bp overlap
ChIP hESC GSE33281.BRD4.hESC 186 bp overlap
ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 275 bp overlap
ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 308 bp overlap
CBFA2T2 1 dataset
ChIP NCCIT GSE71675.CBFA2T2.NCCIT 225 bp overlap
CHD4 1 dataset
ChIP SCMC GSE155861.CHD4.SCMC 489 bp overlap
CHD7 1 dataset
ChIP WA01 ENCSR000AVA.CHD7.WA01 158 bp overlap
CREB1 1 dataset
ChIP WA01 ENCSR000BSN.CREB1.WA01 124 bp overlap
CREM 1 dataset
ChIP K-562 ENCSR077DKV.CREM.K-562 125 bp overlap
CTBP1 1 dataset
ChIP K-562 ENCSR201NQZ.CTBP1.K-562 283 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF031ISE 327 bp overlap
EP300 1 dataset
ChIP sigmoid colon ENCFF524QSR 92 bp overlap
ESR1 4 datasets
ChIP Ishikawa_E2-1h GSE129803.ESR1.Ishikawa_E2-1h 250 bp overlap
ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 318 bp overlap
ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 381 bp overlap
ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 309 bp overlap
FOXA1 2 datasets
ChIP VCaP_DHT24H GSE58428.FOXA1.VCaP_DHT24H 108 bp overlap
ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 285 bp overlap
FOXL2 2 datasets
ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 92 bp overlap
ChIP HGrC1_C134W-TGF_parental GSE138496.FOXL2.HGrC1_C134W-TGF_parental 69 bp overlap
GATA2 1 dataset
ChIP ESF GSE108408.GATA2.ESF 60 bp overlap
GLIS3 1 dataset
ChIP H9_plus GSE109562.GLIS3.H9_plus 350 bp overlap
HDAC2 2 datasets
ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 244 bp overlap
ChIP WA01 ENCSR000AVB.HDAC2.WA01 329 bp overlap
IRF2 1 dataset
Motif DE_12h DE_12h-IRF2_MA0051.2 16 bp overlap
IRF3 1 dataset
Motif DE_12h DE_12h-IRF3_MA1418.2 17 bp overlap
IRF4 1 dataset
Motif DE_12h DE_12h-IRF4_MA1419.2 14 bp overlap
Isl1 1 dataset
Motif DE_12h DE_12h-Isl1_MA1608.2 7 bp overlap
JUND 1 dataset
ChIP H1 ENCFF468JZD 188 bp overlap
KDM4A 1 dataset
ChIP WA01 ENCSR000AVC.KDM4A.WA01 204 bp overlap
KLF1 1 dataset
Motif DE_12h DE_12h-KLF1_MA0493.3 8 bp overlap
KLF10 1 dataset
Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap
KLF12 1 dataset
Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap
KLF14 1 dataset
Motif DE_12h DE_12h-KLF14_MA0740.2 9 bp overlap
KLF16 1 dataset
Motif DE_12h DE_12h-KLF16_MA0741.1 11 bp overlap
KLF2 1 dataset
Motif DE_12h DE_12h-KLF2_MA1515.2 8 bp overlap
KLF4 2 datasets
Motif DE_12h DE_12h-KLF4_MA0039.5 8 bp overlap
ChIP hiPSC GSE56567.KLF4.hiPSC 145 bp overlap
KLF5 2 datasets
Motif DE_12h DE_12h-KLF5_MA0599.1 10 bp overlap
ChIP ESO-26 GSE132680.KLF5.ESO-26 289 bp overlap
KLF6 1 dataset
ChIP PDAC GSE64557.KLF6.PDAC 313 bp overlap
KLF9 2 datasets
Motif DE_12h DE_12h-KLF9_MA1107.3 11 bp overlap
ChIP GBM1A GSE62211.KLF9.GBM1A 125 bp overlap
MAX 6 datasets
ChIP H1 ENCFF914VQY 242 bp overlap
ChIP K-562 ENCSR000EFV.MAX.K-562 130 bp overlap
ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 528 bp overlap
ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 528 bp overlap
ChIP liver ENCFF584QGB 305 bp overlap
ChIP liver ENCSR521IID.MAX.liver 191 bp overlap
MAZ 4 datasets
Motif DE_12h DE_12h-MAZ_MA1522.2 8 bp overlap
ChIP HEK293 GSE76494.MAZ.HEK293 150 bp overlap
ChIP K-562 ENCSR000EFX.MAZ.K-562 157 bp overlap
ChIP K562 ENCFF333ZIV 297 bp overlap
MED1 2 datasets
ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 154 bp overlap
ChIP NCI-H2171 GSE36354.MED1.NCI-H2171 443 bp overlap
MSC 1 dataset
Motif DE_12h DE_12h-MSC_MA0665.1 10 bp overlap
MTA2 1 dataset
ChIP RH4 GSE155861.MTA2.RH4 167 bp overlap
MYC 3 datasets
ChIP NCI-H128 GSE41105.MYC.NCI-H128 179 bp overlap
ChIP NCI-H128 GSE41105.MYC.NCI-H128 146 bp overlap
ChIP NCI-H2171 GSE36354.MYC.NCI-H2171 528 bp overlap
MYCN 2 datasets
ChIP LA-N-5 GSE138295.MYCN.LA-N-5 360 bp overlap
ChIP LNCaP_DHT GSE117304.MYCN.LNCaP_DHT 170 bp overlap
MYOD1 2 datasets
ChIP RH4 GSE83726.MYOD1.RH4 433 bp overlap
ChIP myoblast GSE50413.MYOD1.myoblast 139 bp overlap
MYOG 3 datasets
Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap
ChIP RH30_DMSO GSE85169.MYOG.RH30_DMSO 248 bp overlap
ChIP RH4 GSE83726.MYOG.RH4 246 bp overlap
NANOG 3 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 511 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 185 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 148 bp overlap
NEUROD1 1 dataset
ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 153 bp overlap
NEUROG2 1 dataset
ChIP MRC-5_NFD_05DPT GSE75910.NEUROG2.MRC-5_NFD_05DPT 269 bp overlap
NFATC3 1 dataset
ChIP Hep-G2 GSE97661.NFATC3.Hep-G2 457 bp overlap
NHLH2 1 dataset
Motif DE_12h DE_12h-NHLH2_MA1529.2 16 bp overlap
NOTCH3 1 dataset
ChIP TALL-1_DMSO GSE104261.NOTCH3.TALL-1_DMSO 192 bp overlap
Neurod2 1 dataset
Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap
OLIG2 1 dataset
ChIP brain-prefrontal-cortex_2018006 GSE129039.OLIG2.brain-prefrontal-cortex_2018006 238 bp overlap
Olig2 1 dataset
Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap
PATZ1 1 dataset
Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap
PCGF1 1 dataset
ChIP WA01 GSE104690.PCGF1.WA01 528 bp overlap
POLR2A 10 datasets
ChIP H1 ENCFF566JSR 528 bp overlap
ChIP H1 ENCFF566JSR 411 bp overlap
ChIP esophagus muscularis mucosa ENCFF617PTB 301 bp overlap
ChIP esophagus muscularis mucosa ENCFF759BBR 257 bp overlap
ChIP gastrocnemius medialis ENCFF081DTE 334 bp overlap
ChIP gastrocnemius medialis ENCFF145VIB 347 bp overlap
ChIP prostate gland ENCFF881OMH 149 bp overlap
ChIP sigmoid colon ENCFF725QFT 65 bp overlap
ChIP spleen ENCFF446ZGT 225 bp overlap
ChIP thyroid gland ENCFF979LRR 397 bp overlap
POU5F1 2 datasets
ChIP BG03 GSE21614.POU5F1.BG03 174 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 263 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 321 bp overlap
PRDM9 1 dataset
Motif DE_12h DE_12h-PRDM9_MA1723.2 20 bp overlap
Prdm15 2 datasets
Motif DE_12h DE_12h-Prdm15_MA1616.2 11 bp overlap
Motif ES_0h ES_0h-Prdm15_MA1616.2 11 bp overlap
RAD21 2 datasets
ChIP RH4 GSE83726.RAD21.RH4 390 bp overlap
ChIP liver ENCFF522JHE 283 bp overlap
RBBP4 1 dataset
ChIP SCMC GSE155861.RBBP4.SCMC 474 bp overlap
RBBP5 2 datasets
ChIP H1 ENCFF905HFL 486 bp overlap
ChIP WA01 ENCSR000AQC.RBBP5.WA01 499 bp overlap
RBM39 1 dataset
ChIP Hep-G2 GSE120104.RBM39.Hep-G2 202 bp overlap
RELA 2 datasets
ChIP HDF_NUTLIN GSE77225.RELA.HDF_NUTLIN 211 bp overlap
ChIP KB GSE52469.RELA.KB 103 bp overlap
RREB1 1 dataset
Motif DE_12h DE_12h-RREB1_MA0073.2 19 bp overlap
RUNX2 1 dataset
ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 56 bp overlap
RXRA 2 datasets
ChIP liver ENCFF077DAP 366 bp overlap
ChIP liver ENCFF807CIA 277 bp overlap
RYBP 1 dataset
ChIP WA01 GSE104690.RYBP.WA01 443 bp overlap
SAP30 1 dataset
ChIP WA01 ENCSR000ATR.SAP30.WA01 295 bp overlap
SIN3A 3 datasets
ChIP WA01 ENCSR000EBO.SIN3A.WA01 139 bp overlap
ChIP WA01 ENCSR000BIS.SIN3A.WA01 355 bp overlap
ChIP WA01 ENCSR000EBO.SIN3A.WA01 216 bp overlap
SIX2 2 datasets
Motif DE_12h DE_12h-SIX2_MA1119.2 11 bp overlap
ChIP HEK GSE73865.SIX2.HEK 160 bp overlap
SIX5 2 datasets
ChIP H1 ENCFF942SOJ 237 bp overlap
ChIP WA01 ENCSR000BIQ.SIX5.WA01 125 bp overlap
SMARCA4 3 datasets
ChIP NSC GSE125033.SMARCA4.NSC 179 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 189 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 471 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 193 bp overlap
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 528 bp overlap
SMARCC1 2 datasets
ChIP hiPSC GSE124903.SMARCC1.hiPSC 329 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 223 bp overlap
SMC1 1 dataset
ChIP monocyte_IFNg-LPS GSE120943.SMC1.monocyte_IFNg-LPS 193 bp overlap
SOX2 1 dataset
ChIP LK2_GFP GSE137459.SOX2.LK2_GFP 176 bp overlap
SP1 4 datasets
Motif DE_12h DE_12h-SP1_MA0079.5 9 bp overlap
ChIP H1 ENCFF263FUH 321 bp overlap
ChIP WA01 ENCSR000BIR.SP1.WA01 401 bp overlap
ChIP liver ENCFF597LFJ 163 bp overlap
SP2 1 dataset
Motif DE_12h DE_12h-SP2_MA0516.3 9 bp overlap
SP3 1 dataset
Motif DE_12h DE_12h-SP3_MA0746.3 11 bp overlap
SP4 1 dataset
Motif DE_12h DE_12h-SP4_MA0685.2 9 bp overlap
SP5 1 dataset
Motif DE_12h DE_12h-SP5_MA1965.2 6 bp overlap
STAT1::STAT2 1 dataset
Motif DE_12h DE_12h-STAT1STAT2_MA0517.2 13 bp overlap
STAT3 3 datasets
ChIP MCF-7_jc5840 GSE126004.STAT3.MCF-7_jc5840 96 bp overlap
ChIP MCF-7_jc5842 GSE126004.STAT3.MCF-7_jc5842 298 bp overlap
ChIP monocyte_IL10 GSE120943.STAT3.monocyte_IL10 149 bp overlap
STAT5B 1 dataset
ChIP CD8_H9RETR GSE64713.STAT5B.CD8_H9RETR 193 bp overlap
TAF1 2 datasets
ChIP H1 ENCFF478SZO 385 bp overlap
ChIP WA01 ENCSR000BHO.TAF1.WA01 388 bp overlap
TARDBP 2 datasets
ChIP K-562 ENCSR429XTR.TARDBP.K-562 193 bp overlap
ChIP K-562 GSE120104.TARDBP.K-562 191 bp overlap
TBL1X 1 dataset
ChIP HEK293T GSE35197.TBL1X.HEK293T 189 bp overlap
TCF12 2 datasets
ChIP H1 ENCFF203EBH 230 bp overlap
ChIP WA01 ENCSR000BIT.TCF12.WA01 155 bp overlap
TFAP4 2 datasets
ChIP K562 ENCFF727PXG 374 bp overlap
ChIP K562 ENCFF727PXG 500 bp overlap
Tcf12 1 dataset
Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap
Twist2 1 dataset
Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap
USF1 2 datasets
ChIP H1 ENCFF090WVU 197 bp overlap
ChIP WA01 ENCSR000BIU.USF1.WA01 438 bp overlap
USF2 1 dataset
ChIP WTC11 ENCFF139JAW 231 bp overlap
VEZF1 1 dataset
ChIP K562 ENCFF053XDV 441 bp overlap
YY1 4 datasets
ChIP WA01 ENCSR000BKD.YY1.WA01 126 bp overlap
ChIP liver ENCFF400MBC 314 bp overlap
ChIP liver ENCFF515BWJ 362 bp overlap
ChIP liver ENCSR994YLZ.YY1.liver 190 bp overlap
ZBTB38 1 dataset
ChIP HepG2 ENCFF875UQX 341 bp overlap
ZEB1 1 dataset
ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 378 bp overlap
ZKSCAN3 1 dataset
Motif DE_12h DE_12h-ZKSCAN3_MA1973.2 14 bp overlap
ZNF148 1 dataset
Motif DE_12h DE_12h-ZNF148_MA1653.2 10 bp overlap
ZNF263 1 dataset
ChIP K-562 ENCSR000EWN.ZNF263.K-562 469 bp overlap
ZNF281 1 dataset
Motif DE_12h DE_12h-ZNF281_MA1630.3 10 bp overlap
ZNF423 1 dataset
ChIP WTC11 ENCFF574PBR 279 bp overlap
ZNF549 1 dataset
Motif DE_12h DE_12h-ZNF549_MA1728.2 8 bp overlap
ZNF550 1 dataset
ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 177 bp overlap
ZNF598 1 dataset
ChIP Hep-G2 ENCSR173NAL.ZNF598.Hep-G2 204 bp overlap
ZNF711 1 dataset
ChIP HEK293T GSE145160.ZNF711.HEK293T 463 bp overlap
Zfx 2 datasets
Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap
Motif ES_0h ES_0h-Zfx_MA0146.3 10 bp overlap
Huangfu Lab · Publications · Resources · Contact