chr5 : 140,574,195 – 140,574,528
333 bp 115 TFs 4 linked genes
This 333 bp open chromatin element is linked to 4 target genes and is bound by 115 transcription factors.
Linked Genes
4 genes
Distance
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000283155 at TSS At TSS Proximity
ENSG00000293600 9.4 kb Proximal Proximity
SLC35A4 9.4 kb Proximal Proximity
APBB3 9.5 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr5:140,569,195 – 140,579,528
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
115 transcription factors
Source
Cell type
ARID4A 1 dataset
ChIP HepG2 ENCFF142DIE 82 bp overlap
ARNT::HIF1A 1 dataset
Motif DE_48h DE_48h-ARNTHIF1A_MA0259.2 5 bp overlap
ARNTL 1 dataset
ChIP HepG2 ENCFF217GCH 50 bp overlap
ATF3 7 datasets
ChIP HCT-116_DMSO GSE74355.ATF3.HCT-116_DMSO 142 bp overlap
ChIP K-562 ENCSR028UIU.ATF3.K-562 203 bp overlap
ChIP K562 ENCFF604FPV 333 bp overlap
ChIP liver ENCFF375GID 163 bp overlap
ChIP liver ENCFF867MFZ 150 bp overlap
ChIP liver ENCSR480LIS.ATF3.liver 273 bp overlap
ChIP liver ENCSR205FOW.ATF3.liver 240 bp overlap
BCL11A 11 datasets
ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 165 bp overlap
ChIP CD34_Day7_15min GSE104676.BCL11A.CD34_Day7_15min 88 bp overlap
ChIP CD34_Day7_30min GSE104676.BCL11A.CD34_Day7_30min 122 bp overlap
ChIP CD34_Day7_60min GSE104676.BCL11A.CD34_Day7_60min 94 bp overlap
ChIP CD34_Day7_90min GSE104676.BCL11A.CD34_Day7_90min 182 bp overlap
ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 144 bp overlap
ChIP CD34_Day9_60min GSE104676.BCL11A.CD34_Day9_60min 67 bp overlap
ChIP CD34_Day9_90min GSE104676.BCL11A.CD34_Day9_90min 78 bp overlap
ChIP HUDEP-2_30min GSE104676.BCL11A.HUDEP-2_30min 161 bp overlap
ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 231 bp overlap
ChIP HUDEP-2_BCL11A-ER-V5 GSE103445.BCL11A.HUDEP-2_BCL11A-ER-V5 188 bp overlap
BHLHE40 1 dataset
ChIP IMR-90 ENCSR957KYB.BHLHE40.IMR-90 222 bp overlap
CBFA2T2 1 dataset
ChIP K562 ENCFF963TXY 285 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 298 bp overlap
ChIP K562 ENCFF673OEZ 103 bp overlap
CEBPA 1 dataset
ChIP liver ERP002306.CEBPA.liver 217 bp overlap
CEBPB 5 datasets
ChIP IMR-90 ENCFF468UGY 224 bp overlap
ChIP K-562 ENCSR000EHE.CEBPB.K-562 169 bp overlap
ChIP K-562 ENCSR000BRQ.CEBPB.K-562 171 bp overlap
ChIP K562 ENCFF189VBN 222 bp overlap
ChIP MV4-11 GSE88746.CEBPB.MV4-11 214 bp overlap
CEBPG 2 datasets
ChIP K-562 ENCSR620VIC.CEBPG.K-562 212 bp overlap
ChIP K562 ENCFF651CMK 273 bp overlap
CTBP1 1 dataset
ChIP K562 ENCFF403WPG 333 bp overlap
CTCF 4 datasets
ChIP A-549 ENCSR000AUF.CTCF.A-549 105 bp overlap
ChIP HT-1080 GSE135580.CTCF.HT-1080 229 bp overlap
ChIP hepatocyte ERP000395.CTCF.hepatocyte 188 bp overlap
ChIP peripheral-blood-neutrophil_US-1 GSE126755.CTCF.peripheral-blood-neutrophil_US-1 150 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF031ISE 215 bp overlap
DMRTA2 1 dataset
Motif DE_48h DE_48h-DMRTA2_MA1478.2 6 bp overlap
EGR1 5 datasets
ChIP K-562 ENCSR000BNE.EGR1.K-562 104 bp overlap
ChIP liver ENCFF130MBW 156 bp overlap
ChIP liver ENCFF911LGW 294 bp overlap
ChIP liver ENCSR736BUG.EGR1.liver 222 bp overlap
ChIP liver ENCSR290ZOS.EGR1.liver 236 bp overlap
ELF1 3 datasets
ChIP Hep-G2 ENCSR321VGW.ELF1.Hep-G2 206 bp overlap
ChIP Hep-G2 ENCSR000BMZ.ELF1.Hep-G2 129 bp overlap
ChIP HepG2 ENCFF367ZWV 258 bp overlap
EOMES 2 datasets
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 269 bp overlap
EP300 2 datasets
ChIP A-549 ENCSR000BPW.EP300.A-549 167 bp overlap
ChIP tibial nerve ENCFF346AYA 333 bp overlap
ESR1 1 dataset
ChIP MCF-7_TamR GSE128445.ESR1.MCF-7_TamR 265 bp overlap
ESRRB 1 dataset
Motif DE_48h DE_48h-ESRRB_MA0141.4 10 bp overlap
ETV1 1 dataset
ChIP GIST-T1 GSE106624.ETV1.GIST-T1 200 bp overlap
Esrrg 1 dataset
Motif DE_48h DE_48h-Esrrg_MA0643.2 9 bp overlap
FOXA1 4 datasets
ChIP A-549 ENCSR000BPX.FOXA1.A-549 137 bp overlap
ChIP liver ENCFF749ERP 315 bp overlap
ChIP liver ENCSR735KEY.FOXA1.liver 226 bp overlap
ChIP liver ERP002306.FOXA1.liver 330 bp overlap
FOXA2 6 datasets
ChIP DE DE-FOXA2-1 333 bp overlap
ChIP DE DE-FOXA2-2 333 bp overlap
ChIP liver ENCFF877SFI 324 bp overlap
ChIP liver ENCFF888VJF 320 bp overlap
ChIP liver ENCSR310NYI.FOXA2.liver 286 bp overlap
ChIP liver ENCSR080XEY.FOXA2.liver 291 bp overlap
FOXC2 1 dataset
Motif DE_48h DE_48h-FOXC2_MA0846.2 11 bp overlap
FOXF2 1 dataset
Motif DE_48h DE_48h-FOXF2_MA0030.2 9 bp overlap
FOXG1 1 dataset
Motif DE_48h DE_48h-FOXG1_MA0613.1 8 bp overlap
FOXK1 1 dataset
Motif DE_48h DE_48h-FOXK1_MA0852.3 7 bp overlap
FOXK2 1 dataset
Motif DE_48h DE_48h-FOXK2_MA1103.3 7 bp overlap
FOXL1 1 dataset
Motif DE_48h DE_48h-FOXL1_MA0033.2 7 bp overlap
FOXO4 1 dataset
Motif DE_48h DE_48h-FOXO4_MA0848.1 7 bp overlap
FOXO6 1 dataset
Motif DE_48h DE_48h-FOXO6_MA0849.1 7 bp overlap
FOXP2 1 dataset
Motif DE_48h DE_48h-FOXP2_MA0593.2 9 bp overlap
FOXP3 1 dataset
Motif DE_48h DE_48h-FOXP3_MA0850.1 7 bp overlap
Foxf1 1 dataset
Motif DE_48h DE_48h-Foxf1_MA1606.2 7 bp overlap
Foxl2 1 dataset
Motif DE_48h DE_48h-Foxl2_MA1607.2 10 bp overlap
Foxo1 1 dataset
Motif DE_48h DE_48h-Foxo1_MA0480.3 7 bp overlap
Foxo3 1 dataset
Motif DE_48h DE_48h-Foxo3_MA0157.4 7 bp overlap
GABPA 2 datasets
ChIP liver ENCFF500III 333 bp overlap
ChIP liver ENCSR038GMB.GABPA.liver 235 bp overlap
GATA1 4 datasets
ChIP CD34_Day9_30min GSE104676.GATA1.CD34_Day9_30min 136 bp overlap
ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 220 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 156 bp overlap
ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 315 bp overlap
GATA2 1 dataset
ChIP primary-endometrial-stromal-cell_IVD_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_IVD_P2 219 bp overlap
GATA4 3 datasets
ChIP A-549 GSE85002.GATA4.A-549 197 bp overlap
ChIP DE DE-GATA4-1 333 bp overlap
ChIP DE DE-GATA4-2 333 bp overlap
GATA6 11 datasets
ChIP AGS GSE51705.GATA6.AGS 151 bp overlap
ChIP DE DE-GATA6-1 333 bp overlap
ChIP DE DE-GATA6-2 333 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 333 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 333 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 333 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 333 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 333 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 333 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 333 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 258 bp overlap
GRHL2 1 dataset
ChIP HBE GSE46194.GRHL2.HBE 202 bp overlap
HDAC1 1 dataset
ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 72 bp overlap
HIC2 1 dataset
Motif DE_48h DE_48h-HIC2_MA0738.2 6 bp overlap
HNF1B 1 dataset
ChIP Hep-G2 ENCSR127XTZ.HNF1B.Hep-G2 176 bp overlap
HNF4A 3 datasets
ChIP liver ENCFF354NRH 272 bp overlap
ChIP liver ENCFF449HPV 259 bp overlap
ChIP liver ERP002306.HNF4A.liver 291 bp overlap
HNF4G 2 datasets
ChIP liver ENCFF170YNZ 327 bp overlap
ChIP liver ENCSR297GII.HNF4G.liver 189 bp overlap
ID3 1 dataset
ChIP K-562 ENCSR005NMT.ID3.K-562 245 bp overlap
IKZF1 2 datasets
ChIP K-562 ENCSR395HWC.IKZF1.K-562 333 bp overlap
ChIP K562 ENCFF348IBL 181 bp overlap
IKZF2 1 dataset
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
JUN 6 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 265 bp overlap
ChIP DE_D1 S13-DE-d1-JUN-exp1 187 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 128 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 333 bp overlap
ChIP DE_D2 S54-DE-d2-JUN-exp2 285 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 333 bp overlap
JUND 4 datasets
ChIP liver ENCFF007WWT 314 bp overlap
ChIP liver ENCFF557PGE 333 bp overlap
ChIP liver ENCSR837GTK.JUND.liver 333 bp overlap
ChIP liver ENCSR196HGZ.JUND.liver 251 bp overlap
KLF11 1 dataset
Motif DE_48h DE_48h-KLF11_MA1512.2 10 bp overlap
KLF9 1 dataset
Motif DE_48h DE_48h-KLF9_MA1107.3 11 bp overlap
MAX 5 datasets
ChIP K-562 ENCSR000EFV.MAX.K-562 115 bp overlap
ChIP liver ENCFF092GVW 328 bp overlap
ChIP liver ENCFF584QGB 333 bp overlap
ChIP liver ENCSR521IID.MAX.liver 331 bp overlap
ChIP liver ENCSR847DIT.MAX.liver 291 bp overlap
MAZ 1 dataset
ChIP IMR-90 ENCSR000EFF.MAZ.IMR-90 126 bp overlap
MED1 1 dataset
ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 177 bp overlap
MGA 1 dataset
Motif DE_48h DE_48h-MGA_MA0801.1 8 bp overlap
MXI1 1 dataset
ChIP IMR-90 ENCSR000EFE.MXI1.IMR-90 116 bp overlap
NONO 1 dataset
ChIP K-562 ENCSR010KFT.NONO.K-562 187 bp overlap
NR2F1 1 dataset
ChIP K-562 ENCSR970NKQ.NR2F1.K-562 329 bp overlap
NR2F2 5 datasets
ChIP liver ENCFF427MRU 333 bp overlap
ChIP liver ENCFF565JGD 309 bp overlap
ChIP liver ENCSR168SMX.NR2F2.liver 333 bp overlap
ChIP liver ENCSR338MMB.NR2F2.liver 333 bp overlap
ChIP uterus_STROMA_ENDOMETRIUM GSE52008.NR2F2.uterus_STROMA_ENDOMETRIUM 240 bp overlap
NR3C1 1 dataset
ChIP BEAS-2B_Veh_IA1 GSE125623.NR3C1.BEAS-2B_Veh_IA1 322 bp overlap
NR6A1 1 dataset
Motif DE_48h DE_48h-NR6A1_MA1541.2 14 bp overlap
Nr1h3::Rxra 1 dataset
Motif DE_48h DE_48h-Nr1h3Rxra_MA0494.2 16 bp overlap
PGR 1 dataset
ChIP myometrium_TP1 GSE137550.PGR.myometrium_TP1 72 bp overlap
POLR2A 2 datasets
ChIP spleen ENCFF044PYR 312 bp overlap
ChIP upper lobe of left lung ENCFF095BJW 303 bp overlap
RAD21 2 datasets
ChIP liver ENCFF485PAC 322 bp overlap
ChIP liver ENCFF522JHE 226 bp overlap
RCOR1 1 dataset
ChIP IMR-90 ENCSR000EFG.RCOR1.IMR-90 136 bp overlap
REST 4 datasets
ChIP liver ENCFF240FWT 333 bp overlap
ChIP liver ENCFF577AZT 333 bp overlap
ChIP liver ENCSR893QWP.REST.liver 224 bp overlap
ChIP liver ENCSR867WPH.REST.liver 305 bp overlap
RXRA 2 datasets
ChIP liver ENCFF077DAP 333 bp overlap
ChIP liver ENCFF807CIA 333 bp overlap
Rhox11 1 dataset
Motif DE_48h DE_48h-Rhox11_MA0629.2 9 bp overlap
SMAD2 3 datasets
Motif DE_48h DE_48h-SMAD2_MA1964.2 6 bp overlap
ChIP endoderm GSE29422.SMAD2.endoderm 310 bp overlap
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 179 bp overlap
SMAD2-3 3 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 333 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 333 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 333 bp overlap
SMAD2_3 5 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 333 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 333 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 333 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 333 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 333 bp overlap
SMAD3 2 datasets
ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 215 bp overlap
ChIP endoderm GSE29422.SMAD3.endoderm 279 bp overlap
SMAD4 1 dataset
ChIP endoderm GSE29422.SMAD4.endoderm 276 bp overlap
SMARCA4 3 datasets
ChIP A-549_AG15684 GSE132290.SMARCA4.A-549_AG15684 176 bp overlap
ChIP A-549_AG15685 GSE132290.SMARCA4.A-549_AG15685 211 bp overlap
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 283 bp overlap
SMARCC1 1 dataset
ChIP DE_D1 S15-DE-d1-BAF155-exp1 114 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 295 bp overlap
SP1 3 datasets
ChIP A-549 ENCSR000BPE.SP1.A-549 254 bp overlap
ChIP liver ENCFF597LFJ 333 bp overlap
ChIP liver ENCFF769YSM 331 bp overlap
SPI1 1 dataset
ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 181 bp overlap
SPIB 1 dataset
Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap
SPIC 1 dataset
Motif DE_48h DE_48h-SPIC_MA0687.2 13 bp overlap
STAT3 5 datasets
ChIP HCC1187 GSE152203.STAT3.HCC1187 333 bp overlap
ChIP HCC1937 GSE152203.STAT3.HCC1937 300 bp overlap
ChIP HCC70 GSE152203.STAT3.HCC70 176 bp overlap
ChIP HCC70_EtOH GSE85579.STAT3.HCC70_EtOH 274 bp overlap
ChIP MDA-MB-468_EtOH GSE85579.STAT3.MDA-MB-468_EtOH 331 bp overlap
Spi1 1 dataset
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
T 1 dataset
ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 197 bp overlap
TAL1 1 dataset
ChIP K-562 GSE107726.TAL1.K-562 327 bp overlap
TBR1 1 dataset
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
TBX1 1 dataset
Motif DE_48h DE_48h-TBX1_MA0805.1 8 bp overlap
TBX15 1 dataset
Motif DE_48h DE_48h-TBX15_MA0803.1 8 bp overlap
TBX18 1 dataset
Motif DE_48h DE_48h-TBX18_MA1565.2 9 bp overlap
TBX2 1 dataset
Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap
TBX20 1 dataset
Motif DE_48h DE_48h-TBX20_MA0689.1 11 bp overlap
TBX21 1 dataset
Motif DE_48h DE_48h-TBX21_MA0690.3 10 bp overlap
TBX3 1 dataset
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
TBX5 1 dataset
Motif DE_48h DE_48h-TBX5_MA0807.1 8 bp overlap
TCF12 1 dataset
ChIP A-549 ENCSR000BQQ.TCF12.A-549 330 bp overlap
TCF21 1 dataset
ChIP HCASMC GSE124011.TCF21.HCASMC 207 bp overlap
TCF3 1 dataset
ChIP K-562 ENCSR970OJY.TCF3.K-562 150 bp overlap
TEAD1 1 dataset
ChIP HUCCT1 GSE68296.TEAD1.HUCCT1 226 bp overlap
TEAD3 1 dataset
ChIP HepG2 ENCFF054UUL 296 bp overlap
TEAD4 3 datasets
Motif DE_48h DE_48h-TEAD4_MA0809.3 8 bp overlap
ChIP PC-9_1DF GSE131687.TEAD4.PC-9_1DF 251 bp overlap
ChIP PC-9_2DF GSE131687.TEAD4.PC-9_2DF 266 bp overlap
THAP1 1 dataset
Motif DE_48h DE_48h-THAP1_MA0597.3 8 bp overlap
Tbx6 1 dataset
Motif DE_48h DE_48h-Tbx6_MA1567.3 9 bp overlap
VDR 1 dataset
ChIP THP-1_1d_1-25-OH-2D3 GSE89431.VDR.THP-1_1d_1-25-OH-2D3 164 bp overlap
YY1 3 datasets
ChIP liver ENCFF400MBC 246 bp overlap
ChIP liver ENCFF515BWJ 333 bp overlap
ChIP liver ENCSR994YLZ.YY1.liver 333 bp overlap
YY1AP1 2 datasets
ChIP PC-9_1DF GSE131687.YY1AP1.PC-9_1DF 293 bp overlap
ChIP PC-9_2DF GSE131687.YY1AP1.PC-9_2DF 302 bp overlap
ZBTB33 3 datasets
ChIP liver ENCFF592BJA 333 bp overlap
ChIP liver ENCFF592BJA 294 bp overlap
ChIP liver ENCSR516HUP.ZBTB33.liver 324 bp overlap
ZNF530 1 dataset
Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap
ZNF85 1 dataset
Motif DE_48h DE_48h-ZNF85_MA1720.2 12 bp overlap
ZNF90 1 dataset
ChIP HEK293T GSE78099.ZNF90.HEK293T 299 bp overlap
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