chr4 : 164,867,096 – 164,867,438
342 bp 106 TFs 1 linked gene
This 342 bp open chromatin element is linked to APELA and is bound by 106 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
APELA 9.7 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:164,862,096 – 164,872,438
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
106 transcription factors
Source
Cell type
ARID1A 1 dataset
ChIP HAP1 GSE108387.ARID1A.HAP1 342 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 278 bp overlap
ATF2 2 datasets
ChIP H1 ENCFF295GZO 342 bp overlap
ChIP WA01 ENCSR000BQU.ATF2.WA01 285 bp overlap
ATF7 1 dataset
ChIP GM12878 ENCSR014YCR.ATF7.GM12878 270 bp overlap
BCOR 1 dataset
ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 326 bp overlap
BRD4 1 dataset
ChIP HAP1 GSE108387.BRD4.HAP1 321 bp overlap
CDX2 1 dataset
Motif ES_0h ES_0h-CDX2_MA0465.3 8 bp overlap
CHD7 3 datasets
ChIP H1 ENCFF126NLU 273 bp overlap
ChIP WA01 ENCSR000AVA.CHD7.WA01 342 bp overlap
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 342 bp overlap
CREB1 3 datasets
ChIP GM23338 ENCFF432ZEW 305 bp overlap
ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 194 bp overlap
ChIP WA01 ENCSR000BSN.CREB1.WA01 129 bp overlap
CTCF 7 datasets
ChIP HAP1 GSE152721.CTCF.HAP1 212 bp overlap
ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 342 bp overlap
ChIP HAP1_clone21_CTCF-TSS-CRISPR_1 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_1 234 bp overlap
ChIP HAP1_clone21_CTCF-TSS-CRISPR_2 GSE152721.CTCF.HAP1_clone21_CTCF-TSS-CRISPR_2 260 bp overlap
ChIP HAP1_clone21_TSS-CRISPR GSE152721.CTCF.HAP1_clone21_TSS-CRISPR 264 bp overlap
ChIP HAP1_clone25 GSE152721.CTCF.HAP1_clone25 192 bp overlap
ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 238 bp overlap
EOMES 2 datasets
Motif ES_0h ES_0h-EOMES_MA0800.2 9 bp overlap
ChIP hESC GSE26097.EOMES.hESC 174 bp overlap
EP300 1 dataset
ChIP hESC GSE17917.EP300.hESC 245 bp overlap
ETV6 1 dataset
ChIP WTC11 ENCFF812SCD 317 bp overlap
FLI1 1 dataset
ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 64 bp overlap
FOXA1 2 datasets
ChIP CFPAC-1_FOXA1-KO GSE119930.FOXA1.CFPAC-1_FOXA1-KO 133 bp overlap
ChIP CFPAC-1_FOXA2-KO GSE119930.FOXA1.CFPAC-1_FOXA2-KO 206 bp overlap
FOXA2 3 datasets
ChIP CFPAC-1_HOXB8-OE GSE119930.FOXA2.CFPAC-1_HOXB8-OE 141 bp overlap
ChIP DE DE-FOXA2-1 111 bp overlap
ChIP DE DE-FOXA2-2 120 bp overlap
FOXP1 2 datasets
ChIP H9 GSE31006.FOXP1.H9 59 bp overlap
ChIP H9 GSE31006.FOXP1.H9 160 bp overlap
HAND2 1 dataset
Motif ES_0h ES_0h-HAND2_MA1638.2 6 bp overlap
HDAC2 3 datasets
ChIP H1 ENCFF353UJQ 342 bp overlap
ChIP H1 ENCFF939VKA 236 bp overlap
ChIP WA01 ENCSR000BNR.HDAC2.WA01 195 bp overlap
HOXB13 3 datasets
ChIP prostate-cancer_PDX_70 GSE130408.HOXB13.prostate-cancer_PDX_70 54 bp overlap
ChIP prostate_2483_T GSE130408.HOXB13.prostate_2483_T 154 bp overlap
ChIP prostate_2484_T GSE130408.HOXB13.prostate_2484_T 175 bp overlap
HOXB8 1 dataset
ChIP CFPAC-1_HOXB8-OE GSE119930.HOXB8.CFPAC-1_HOXB8-OE 120 bp overlap
HOXC6 1 dataset
ChIP 22Rv1 GSE129951.HOXC6.22Rv1 98 bp overlap
IKZF1 1 dataset
ChIP GM12878 ENCFF753XDO 180 bp overlap
IKZF2 4 datasets
ChIP GM12878 ENCFF238LYK 342 bp overlap
ChIP GM12878 ENCFF918AID 342 bp overlap
ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 342 bp overlap
ChIP GM12878 ENCSR822AHX.IKZF2.GM12878 253 bp overlap
JUN 4 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 292 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 342 bp overlap
ChIP ESC S34-ESC-d0-JUN-exp2 342 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 342 bp overlap
JUND 1 dataset
ChIP H1 ENCFF010YXS 311 bp overlap
KLF17 1 dataset
Motif ES_0h ES_0h-KLF17_MA1514.2 14 bp overlap
KLF4 2 datasets
ChIP HAP1 GSE130417.KLF4.HAP1 179 bp overlap
ChIP WA09 GSE105028.KLF4.WA09 247 bp overlap
MED1 1 dataset
ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 342 bp overlap
MGA 1 dataset
Motif ES_0h ES_0h-MGA_MA0801.1 8 bp overlap
MLLT1 1 dataset
ChIP GM12878 ENCSR552XSN.MLLT1.GM12878 342 bp overlap
MSANTD3 1 dataset
Motif ES_0h ES_0h-MSANTD3_MA1523.2 7 bp overlap
MTA2 1 dataset
ChIP GM12878 ENCSR293QAR.MTA2.GM12878 212 bp overlap
MYCN 1 dataset
ChIP SHEP-21N GSE80151.MYCN.SHEP-21N 249 bp overlap
Msgn1 1 dataset
Motif ES_0h ES_0h-Msgn1_MA1524.3 10 bp overlap
NANOG 9 datasets
ChIP GM23338 ENCFF065NZG 80 bp overlap
ChIP GM23338 ENCSR061DGF.NANOG.GM23338 342 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 342 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 342 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 342 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 342 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 342 bp overlap
ChIP hESC GSE18292.NANOG.hESC 342 bp overlap
ChIP hESC GSE20650.NANOG.hESC 342 bp overlap
NFYA 1 dataset
Motif ES_0h ES_0h-NFYA_MA0060.4 8 bp overlap
NFYB 4 datasets
Motif ES_0h ES_0h-NFYB_MA0502.3 9 bp overlap
ChIP GM12878 ENCFF474DNH 314 bp overlap
ChIP GM12878 ENCSR000DNM.NFYB.GM12878 217 bp overlap
ChIP WTC11 ENCFF751ZTQ 298 bp overlap
NFYC 1 dataset
Motif ES_0h ES_0h-NFYC_MA1644.2 7 bp overlap
NKX2-2 1 dataset
Motif ES_0h ES_0h-NKX2-2_MA1645.2 8 bp overlap
NR1H4::RXRA 1 dataset
Motif ES_0h ES_0h-NR1H4RXRA_MA1146.2 13 bp overlap
NR2F1 1 dataset
Motif ES_0h ES_0h-NR2F1_MA1538.1 15 bp overlap
Nr2F6 1 dataset
Motif ES_0h ES_0h-Nr2F6_MA0728.1 15 bp overlap
Nr2e1 1 dataset
Motif ES_0h ES_0h-Nr2e1_MA0676.1 9 bp overlap
OSR2 1 dataset
Motif ES_0h ES_0h-OSR2_MA1646.2 8 bp overlap
PDX1 1 dataset
ChIP hiPSC GSE125768.PDX1.hiPSC 160 bp overlap
PKNOX1 1 dataset
ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 298 bp overlap
POLR2A 2 datasets
ChIP GM23338 ENCFF450WCS 315 bp overlap
ChIP SK-N-MC ENCFF088IVG 138 bp overlap
POU4F2 1 dataset
ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 153 bp overlap
POU5F1 12 datasets
ChIP GM23338 ENCFF333SNB 302 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 342 bp overlap
ChIP NCCIT GSE36134.POU5F1.NCCIT 284 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 342 bp overlap
ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 329 bp overlap
ChIP WA09 GSE105028.POU5F1.WA09 342 bp overlap
ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 342 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 342 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 342 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 342 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 342 bp overlap
ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 342 bp overlap
PRDM14 2 datasets
ChIP hESC GSE22767.PRDM14.hESC 316 bp overlap
ChIP hESC GSE138674.PRDM14.hESC 187 bp overlap
Pparg::Rxra 2 datasets
Motif ES_0h ES_0h-PpargRxra_MA0065.3 13 bp overlap
Motif ES_0h ES_0h-PpargRxra_MA0065.3 13 bp overlap
RAD21 4 datasets
ChIP HAP1 GSE152721.RAD21.HAP1 342 bp overlap
ChIP HAP1 GSE126634.RAD21.HAP1 342 bp overlap
ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 342 bp overlap
ChIP HAP1_clone25 GSE152721.RAD21.HAP1_clone25 342 bp overlap
RAD51 1 dataset
ChIP GM12878 ENCSR482TWQ.RAD51.GM12878 216 bp overlap
RARA 3 datasets
Motif ES_0h ES_0h-RARA_MA0729.1 18 bp overlap
ChIP hiPSC_D4 GSE109172.RARA.hiPSC_D4 177 bp overlap
ChIP hiPSC_D5 GSE132532.RARA.hiPSC_D5 174 bp overlap
RBPJ 2 datasets
ChIP GSC8-11_dasatinib GSE74557.RBPJ.GSC8-11_dasatinib 58 bp overlap
ChIP GSC8-11_dasatinib GSE74557.RBPJ.GSC8-11_dasatinib 244 bp overlap
RELB 1 dataset
ChIP GM12878 ENCSR387QUV.RELB.GM12878 342 bp overlap
Rarb 1 dataset
Motif ES_0h ES_0h-Rarb_MA0857.1 16 bp overlap
Rarg 1 dataset
Motif ES_0h ES_0h-Rarg_MA0859.2 15 bp overlap
SIN3A 1 dataset
ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 157 bp overlap
SKIL 1 dataset
ChIP GM12878 ENCSR212YKD.SKIL.GM12878 279 bp overlap
SMAD1 2 datasets
ChIP BG03 GSE36578.SMAD1.BG03 96 bp overlap
ChIP GM12878 ENCSR813DCK.SMAD1.GM12878 241 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 112 bp overlap
SMAD2_3 1 dataset
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 236 bp overlap
SMAD3 2 datasets
ChIP BG03 GSE21614.SMAD3.BG03 191 bp overlap
ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 186 bp overlap
SMARCA2 1 dataset
ChIP SK-N-MC_shEWSFLI1 GSE94275.SMARCA2.SK-N-MC_shEWSFLI1 171 bp overlap
SMARCA4 7 datasets
ChIP Aska-SS GSE108025.SMARCA4.Aska-SS 164 bp overlap
ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 205 bp overlap
ChIP NSC GSE125033.SMARCA4.NSC 336 bp overlap
ChIP WA09 GSE105028.SMARCA4.WA09 342 bp overlap
ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 342 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 342 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 342 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 342 bp overlap
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 262 bp overlap
SMARCC1 5 datasets
ChIP Aska-SS GSE108025.SMARCC1.Aska-SS 289 bp overlap
ChIP ESC S25-ESC-d0-BAF155-exp1 305 bp overlap
ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 79 bp overlap
ChIP hiPSC GSE124903.SMARCC1.hiPSC 342 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 342 bp overlap
SOX10 2 datasets
Motif ES_0h ES_0h-SOX10_MA0442.3 6 bp overlap
Motif ES_0h ES_0h-SOX10_MA0442.3 6 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 157 bp overlap
SOX2 4 datasets
ChIP HNSC GSE69479.SOX2.HNSC 334 bp overlap
ChIP hESC GSE69479.SOX2.hESC 329 bp overlap
ChIP hESC GSE18292.SOX2.hESC 83 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 342 bp overlap
SOX4 2 datasets
Motif ES_0h ES_0h-SOX4_MA0867.3 8 bp overlap
Motif ES_0h ES_0h-SOX4_MA0867.3 8 bp overlap
SP1 2 datasets
ChIP H1 ENCFF263FUH 287 bp overlap
ChIP WA01 ENCSR000BIR.SP1.WA01 197 bp overlap
SREBF1 1 dataset
Motif ES_0h ES_0h-SREBF1_MA0595.1 10 bp overlap
SREBF2 1 dataset
Motif ES_0h ES_0h-SREBF2_MA0596.1 10 bp overlap
Sox11 1 dataset
Motif ES_0h ES_0h-Sox11_MA0869.3 8 bp overlap
Sox17 1 dataset
Motif ES_0h ES_0h-Sox17_MA0078.3 10 bp overlap
Sox6 2 datasets
Motif ES_0h ES_0h-Sox6_MA0515.1 10 bp overlap
Motif ES_0h ES_0h-Sox6_MA0515.1 10 bp overlap
Sox7 1 dataset
Motif ES_0h ES_0h-Sox7_MA2095.1 10 bp overlap
TARDBP 1 dataset
ChIP GM12878 ENCSR412QBS.TARDBP.GM12878 303 bp overlap
TBP 1 dataset
ChIP hESC_2h GSE122298.TBP.hESC_2h 137 bp overlap
TBR1 1 dataset
Motif ES_0h ES_0h-TBR1_MA0802.2 9 bp overlap
TBX1 1 dataset
Motif ES_0h ES_0h-TBX1_MA0805.1 8 bp overlap
TBX15 1 dataset
Motif ES_0h ES_0h-TBX15_MA0803.1 8 bp overlap
TBX18 1 dataset
Motif ES_0h ES_0h-TBX18_MA1565.2 9 bp overlap
TBX2 1 dataset
Motif ES_0h ES_0h-TBX2_MA0688.2 9 bp overlap
TBX20 1 dataset
Motif ES_0h ES_0h-TBX20_MA0689.1 11 bp overlap
TBX21 2 datasets
Motif ES_0h ES_0h-TBX21_MA0690.3 10 bp overlap
ChIP GM12878 ENCSR739IHN.TBX21.GM12878 246 bp overlap
TBX3 1 dataset
Motif ES_0h ES_0h-TBX3_MA1566.3 9 bp overlap
TBX5 1 dataset
Motif ES_0h ES_0h-TBX5_MA0807.1 8 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 288 bp overlap
TCF7L1 1 dataset
Motif ES_0h ES_0h-TCF7L1_MA1421.1 12 bp overlap
TEAD4 2 datasets
ChIP ESC S26-ESC-d0-TEAD4-exp1 341 bp overlap
ChIP hESC GSE99202.TEAD4.hESC 239 bp overlap
TLE3 1 dataset
ChIP LNCaP GSE94682.TLE3.LNCaP 66 bp overlap
TP53 3 datasets
ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 342 bp overlap
ChIP hESC_DAMAGED GSE39912.TP53.hESC_DAMAGED 237 bp overlap
ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 258 bp overlap
TRIM22 1 dataset
ChIP GM12878 ENCSR835XKS.TRIM22.GM12878 342 bp overlap
TWIST1 4 datasets
ChIP SHEP-21N GSE80151.TWIST1.SHEP-21N 292 bp overlap
ChIP SHEP-21N GSE80151.TWIST1.SHEP-21N 202 bp overlap
ChIP SHEP-21N_24h GSE80151.TWIST1.SHEP-21N_24h 207 bp overlap
ChIP SHEP-21N_DOX_0H GSE80151.TWIST1.SHEP-21N_DOX_0H 292 bp overlap
Tbx6 1 dataset
Motif ES_0h ES_0h-Tbx6_MA1567.3 9 bp overlap
YBX1 1 dataset
ChIP GM12878 ENCSR205SKQ.YBX1.GM12878 342 bp overlap
YY1AP1 1 dataset
ChIP HEK293_siCtrl GSE130135.YY1AP1.HEK293_siCtrl 211 bp overlap
ZNF184 1 dataset
ChIP WTC11 ENCFF352POG 342 bp overlap
ZNF207 1 dataset
ChIP WA09 GSE118632.ZNF207.WA09 342 bp overlap
ZNF462 1 dataset
ChIP GM23338 ENCFF896CCA 251 bp overlap
ZNF701 1 dataset
Motif ES_0h ES_0h-ZNF701_MA1987.2 17 bp overlap
ZNF85 1 dataset
Motif ES_0h ES_0h-ZNF85_MA1720.2 12 bp overlap
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