chr2:74,026,198–74,026,578

chr2 : 74,026,198 – 74,026,578

380 bp 88 TFs 9 linked genes

This 380 bp open chromatin element is linked to 9 target genes and is bound by 88 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TET3		41.5 kb	Distal	Multiome
DGUOK		99.6 kb	Distal	Multiome
BOLA3		121.5 kb	Distal	Multiome
BOLA3-DT		121.6 kb	Distal	Multiome
MOB1A		152.4 kb	Distal	Multiome
MTHFD2		172.2 kb	Distal	Multiome
STAMBP		197.5 kb	Distal	Multiome
DUSP11		246.3 kb	Distal	Multiome
TPRKB		289.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

88 transcription factors

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 295 bp overlap

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 219 bp overlap

ChIP K562 ENCFF938UXQ 160 bp overlap

ASH2L 2 datasets

ChIP GM12878 ENCSR849WCQ.ASH2L.GM12878 241 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 279 bp overlap

BCL11A 14 datasets

ChIP CD34_Day3_30min GSE104676.BCL11A.CD34_Day3_30min 60 bp overlap

ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 127 bp overlap

ChIP CD34_Day7_30min GSE104676.BCL11A.CD34_Day7_30min 87 bp overlap

ChIP CD34_Day7_30min GSE104676.BCL11A.CD34_Day7_30min 121 bp overlap

ChIP CD34_Day7_60min GSE104676.BCL11A.CD34_Day7_60min 111 bp overlap

ChIP CD34_Day7_90min GSE104676.BCL11A.CD34_Day7_90min 57 bp overlap

ChIP CD34_Day7_90min GSE104676.BCL11A.CD34_Day7_90min 116 bp overlap

ChIP CD34_Day9_15min GSE104676.BCL11A.CD34_Day9_15min 57 bp overlap

ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 120 bp overlap

ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 140 bp overlap

ChIP CD34_Day9_60min GSE104676.BCL11A.CD34_Day9_60min 117 bp overlap

ChIP CD34_Day9_90min GSE104676.BCL11A.CD34_Day9_90min 127 bp overlap

ChIP CD34_Day9_90min GSE104676.BCL11A.CD34_Day9_90min 131 bp overlap

ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 93 bp overlap

ChIP OCI-Ly1 GSE29282.BCL6.OCI-Ly1 347 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 137 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 272 bp overlap

BRD2 2 datasets

ChIP K-562_DMSO GSE138084.BRD2.K-562_DMSO 215 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD2.K-562_DMSO-IFNG 213 bp overlap

BRD3 3 datasets

ChIP K-562_DMSO GSE138084.BRD3.K-562_DMSO 307 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 244 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD3.K-562_iBET-BD2-IFNG 199 bp overlap

BRD4 5 datasets

ChIP K-562_DMSO GSE138084.BRD4.K-562_DMSO 255 bp overlap

ChIP K-562_iBET-BD1-IFNG GSE138084.BRD4.K-562_iBET-BD1-IFNG 340 bp overlap

ChIP K-562_iBET-BD2 GSE138084.BRD4.K-562_iBET-BD2 234 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 297 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD4.K-562_iBET-IFNG 184 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 187 bp overlap

ChIP K562 ENCFF673OEZ 204 bp overlap

ChIP SET-2 GSE65138.CDK8.SET-2 83 bp overlap

ChIP H1 ENCFF126NLU 316 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 240 bp overlap

CREBBP 1 dataset

ChIP keratinocyte GSE140991.CREBBP.keratinocyte 125 bp overlap

ChIP GM12878 ENCSR509FWH.DPF2.GM12878 367 bp overlap

ChIP K-562 ENCSR731LHZ.E4F1.K-562 95 bp overlap

EP300 1 dataset

ChIP GM12878 ENCFF242HCG 137 bp overlap

GATA1 8 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 85 bp overlap

ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 101 bp overlap

ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 116 bp overlap

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 80 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 218 bp overlap

ChIP erythroblast ENCFF867JAR 361 bp overlap

ChIP erythroblast ENCFF867JAR 158 bp overlap

ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 370 bp overlap

GATA2 1 dataset

ChIP TF1 GSE73207.GATA2.TF1 125 bp overlap

GATA6 4 datasets

ChIP DE_D1 S14-DE-d1-GATA6-exp1 147 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 139 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 163 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 288 bp overlap

HDAC2 1 dataset

ChIP Hep-G2 ENCSR000BMC.HDAC2.Hep-G2 116 bp overlap

HDGF 2 datasets

ChIP K-562 ENCSR563YDA.HDGF.K-562 327 bp overlap

ChIP K-562 ENCSR197ALX.HDGF.K-562 181 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 219 bp overlap

HMBOX1 3 datasets

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 318 bp overlap

ChIP K562 ENCFF055GAZ 355 bp overlap

ChIP K562 ENCFF317JJX 368 bp overlap

HNF4A 6 datasets

ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 103 bp overlap

ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 138 bp overlap

ChIP Hep-G2 ENCSR000BLF.HNF4A.Hep-G2 92 bp overlap

ChIP Hep-G2 ERP000209.HNF4A.Hep-G2 134 bp overlap

ChIP IM95 GSE114018.HNF4A.IM95 99 bp overlap

ChIP gastric-epithelial-cell_OE GSE114018.HNF4A.gastric-epithelial-cell_OE 144 bp overlap

HNF4G 1 dataset

ChIP Hep-G2 ENCSR000BNJ.HNF4G.Hep-G2 85 bp overlap

IKZF1 2 datasets

ChIP GM12878 ENCFF753XDO 294 bp overlap

ChIP K-562 ENCSR395HWC.IKZF1.K-562 380 bp overlap

IKZF2 3 datasets

ChIP GM12878 ENCFF238LYK 380 bp overlap

ChIP GM12878 ENCSR680UQE.IKZF2.GM12878 353 bp overlap

ChIP GM12878 ENCSR822AHX.IKZF2.GM12878 247 bp overlap

ChIP keratinocyte_DOX GSE135677.IRF2.keratinocyte_DOX 174 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 258 bp overlap

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 380 bp overlap

ChIP keratinocyte GSE140991.KLF3.keratinocyte 246 bp overlap

KMT2A 4 datasets

ChIP CCRF-CEM GSE83671.KMT2A.CCRF-CEM 221 bp overlap

ChIP KOPN-8 GSE83671.KMT2A.KOPN-8 289 bp overlap

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 346 bp overlap

ChIP blood_cord GSE83671.KMT2A.blood_cord 316 bp overlap

LDB1 2 datasets

ChIP HEP GSE52637.LDB1.HEP 157 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 172 bp overlap

ChIP P493-6 GSE36354.MAX.P493-6 307 bp overlap

MEF2B 1 dataset

ChIP GM12878 ENCSR177VFS.MEF2B.GM12878 233 bp overlap

MTA2 2 datasets

ChIP GM12878 ENCFF615CWQ 76 bp overlap

ChIP GM12878 ENCSR293QAR.MTA2.GM12878 328 bp overlap

ChIP GM12878 ENCFF666NJR 154 bp overlap

ChIP MCF-7 ENCSR000DMQ.MYC.MCF-7 78 bp overlap

ChIP P493-6 GSE77061.MYC.P493-6 86 bp overlap

NANOG 11 datasets

ChIP GM23338 ENCFF065NZG 208 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 166 bp overlap

ChIP H1 ENCFF747ZPQ 166 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 343 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 187 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 157 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 222 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 320 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 272 bp overlap

ChIP hESC GSE20650.NANOG.hESC 143 bp overlap

ChIP hESC GSE18292.NANOG.hESC 102 bp overlap

ChIP GM12878 ENCFF213ZNN 137 bp overlap

ChIP GM12878 ENCSR278SQL.NBN.GM12878 225 bp overlap

NCOR1 1 dataset

ChIP K-562 ENCSR798ILC.NCOR1.K-562 135 bp overlap

NELFE 1 dataset

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 207 bp overlap

NFATC3 2 datasets

ChIP GM12878 ENCFF340KVJ 105 bp overlap

ChIP GM12878 ENCSR437GBJ.NFATC3.GM12878 263 bp overlap

ChIP ProEs GSE59087.NFE2.ProEs 187 bp overlap

NKX2-1 1 dataset

ChIP H9_derived-cIN GSE99937.NKX2-1.H9_derived-cIN 96 bp overlap

PKNOX1 1 dataset

ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 91 bp overlap

ChIP GM12878 ENCFF160JQZ 58 bp overlap

POLR2A 2 datasets

ChIP GM12891 ENCFF012SUT 152 bp overlap

ChIP Peyer's patch ENCFF767HVN 113 bp overlap

POU2F2 1 dataset

ChIP GM12891 ENCFF166YPP 262 bp overlap

POU5F1 13 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 380 bp overlap

ChIP GM23338 ENCFF333SNB 255 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 294 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 291 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 292 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 187 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 228 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 157 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 368 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 299 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 190 bp overlap

ChIP hiPSC GSE149017.POU5F1.hiPSC 117 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 167 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 380 bp overlap

PROX1 2 datasets

ChIP SW480 GSE60390.PROX1.SW480 136 bp overlap

ChIP SW480 GSE60390.PROX1.SW480 86 bp overlap

RBBP5 1 dataset

ChIP K-562 ENCSR000AQI.RBBP5.K-562 108 bp overlap

RBM39 1 dataset

ChIP K-562 ENCSR764OXF.RBM39.K-562 237 bp overlap

RELB 2 datasets

ChIP GM12878 ENCFF217ADF 121 bp overlap

ChIP GM12878 ENCSR387QUV.RELB.GM12878 246 bp overlap

RUNX1 1 dataset

ChIP BCP-ALL_patient1 GSE109377.RUNX1.BCP-ALL_patient1 380 bp overlap

RUNX1T1 1 dataset

ChIP Kasumi-1 GSE115115.RUNX1T1.Kasumi-1 235 bp overlap

SAFB2 1 dataset

ChIP Hep-G2 GSE120104.SAFB2.Hep-G2 218 bp overlap

SMARCA4 5 datasets

ChIP J-Lat_GFP-Clone-A72_DMSO GSE100266.SMARCA4.J-Lat_GFP-Clone-A72_DMSO 240 bp overlap

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 338 bp overlap

ChIP WA09 GSE105028.SMARCA4.WA09 204 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 312 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 312 bp overlap

SMARCA5 1 dataset

ChIP GM12878 ENCSR706YUH.SMARCA5.GM12878 184 bp overlap

SMARCB1 1 dataset

ChIP hiPSC GSE124903.SMARCB1.hiPSC 286 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 228 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 346 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 288 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 86 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 228 bp overlap

ChIP OCI-Ly3 GSE56857.SPIB.OCI-Ly3 229 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 380 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 179 bp overlap

TAL1 12 datasets

ChIP CD34 GSE52924.TAL1.CD34 168 bp overlap

ChIP HSPC-CD34pos GSE93372.TAL1.HSPC-CD34pos 140 bp overlap

ChIP K-562 ENCSR106FRG.TAL1.K-562 223 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 180 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 169 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 152 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 133 bp overlap

ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 133 bp overlap

ChIP K562 ENCFF620GMX 132 bp overlap

ChIP K562 ENCFF661CCK 177 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 151 bp overlap

ChIP erythroid GSE42390.TAL1.erythroid 131 bp overlap

TARDBP 2 datasets

ChIP GM12878 ENCSR412QBS.TARDBP.GM12878 224 bp overlap

ChIP K-562 GSE120104.TARDBP.K-562 195 bp overlap

TBX21 5 datasets

ChIP CD4_Th1 GSE62482.TBX21.CD4_Th1 156 bp overlap

ChIP GM12878 ENCFF951HUW 344 bp overlap

ChIP GM12878 ENCFF951HUW 217 bp overlap

ChIP GM12878 ENCSR739IHN.TBX21.GM12878 380 bp overlap

ChIP Th1_CD3-CD28_donor2 GSE81881.TBX21.Th1_CD3-CD28_donor2 266 bp overlap

TCF12 3 datasets

ChIP GM12878 ENCFF433DMU 158 bp overlap

ChIP K-562 ENCSR744WOO.TCF12.K-562 179 bp overlap

ChIP K562 ENCFF931DJY 290 bp overlap

ChIP K-562 ENCSR970OJY.TCF3.K-562 148 bp overlap

TERF1 1 dataset

ChIP LCL GSE55053.TERF1.LCL 183 bp overlap

TFAP2A 1 dataset

ChIP WA09 GSE105081.TFAP2A.WA09 167 bp overlap

TFAP2C 3 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 380 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 380 bp overlap

ChIP WA09 GSE105081.TFAP2C.WA09 143 bp overlap

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 380 bp overlap

TRIM22 1 dataset

ChIP GM12878 ENCSR835XKS.TRIM22.GM12878 209 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 286 bp overlap

ChIP Hep-G2 ENCSR000BNT.YY1.Hep-G2 292 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 237 bp overlap

ZBTB7A 3 datasets

ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 172 bp overlap

ChIP Hep-G2 ENCSR000BQA.ZBTB7A.Hep-G2 105 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 177 bp overlap

ChIP K-562 ENCSR004GKA.ZEB2.K-562 278 bp overlap

ZMYM3 1 dataset

ChIP K-562_Ab_JH39-2-2F10 GSE97661.ZMYM3.K-562_Ab_JH39-2-2F10 194 bp overlap

ZNF398 2 datasets

ChIP BG01V GSE133630.ZNF398.BG01V 145 bp overlap

ChIP H9 GSE133630.ZNF398.H9 162 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 283 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 201 bp overlap

ZNF592 1 dataset

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 228 bp overlap

ZNF687 1 dataset

ChIP HepG2 ENCFF653WIX 319 bp overlap