chr1:32,437,702–32,438,502

chr1 : 32,437,702 – 32,438,502

800 bp 85 TFs 14 linked genes

This 800 bp open chromatin element is linked to 14 target genes and is bound by 85 transcription factors.

Linked Genes

14 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ZBTB8B		26.8 kb	Distal	Multiome
BSDC1		43.8 kb	Distal	Multiome
ZBTB8A		101.2 kb	Distal	Multiome
MARCKSL1		102.0 kb	Distal	Multiome
HDAC1		146.1 kb	Distal	Multiome
LCK		164.2 kb	Distal	Multiome
ENSG00000291132		196.7 kb	Distal	Multiome
ZBTB8OS		212.3 kb	Distal	Multiome
RBBP4		213.0 kb	Distal	Multiome
EIF3I		215.8 kb	Distal	Multiome
TMEM234		215.9 kb	Distal	Multiome
CCDC28B		237.6 kb	Distal	Multiome
TXLNA		258.2 kb	Distal	Multiome
SYNC		264.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

85 transcription factors

ASH2L 2 datasets

ChIP WA01 ENCSR850KIP.ASH2L.WA01 446 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 90 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 172 bp overlap

BCL11A 2 datasets

ChIP H1 ENCFF833IPY 145 bp overlap

ChIP WA01 ENCSR000BIP.BCL11A.WA01 248 bp overlap

BHLHE22 1 dataset

Motif ES_0h ES_0h-BHLHE22_MA1635.2 6 bp overlap

Bhlha15 1 dataset

Motif ES_0h ES_0h-Bhlha15_MA1472.3 8 bp overlap

ChIP H1 ENCFF126NLU 343 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 150 bp overlap

Motif ES_0h ES_0h-CTCF_MA0139.2 15 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 193 bp overlap

EP300 2 datasets

ChIP WA01 ENCSR000BKK.EP300.WA01 236 bp overlap

ChIP hESC GSE17917.EP300.hESC 252 bp overlap

ESR1 2 datasets

ChIP MCF-7_E2+4OHT_SRC-3 GSE119702.ESR1.MCF-7_E2+4OHT_SRC-3 288 bp overlap

ChIP MCF-7_SRC3_OHT GSE119702.ESR1.MCF-7_SRC3_OHT 288 bp overlap

ESRRA 1 dataset

ChIP WTC11 ENCFF591YCA 425 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 800 bp overlap

ChIP DE DE-FOXA2-2 754 bp overlap

GATA1::TAL1 1 dataset

Motif ES_0h ES_0h-GATA1TAL1_MA0140.3 17 bp overlap

GATA2 1 dataset

Motif ES_0h ES_0h-GATA2_MA0036.4 7 bp overlap

GATA3 4 datasets

ChIP MCF-7 ENCFF352QVM 437 bp overlap

ChIP MCF-7 ENCFF437NQS 371 bp overlap

ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 164 bp overlap

ChIP MCF-7_E2_Dex GSE81510.GATA3.MCF-7_E2_Dex 179 bp overlap

GATA4 6 datasets

ChIP DE DE-GATA4-1 800 bp overlap

ChIP DE DE-GATA4-2 800 bp overlap

Motif ES_0h ES_0h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 347 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 378 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 207 bp overlap

GATA5 1 dataset

Motif ES_0h ES_0h-GATA5_MA0766.3 8 bp overlap

GATA6 14 datasets

ChIP DE DE-GATA6-1 744 bp overlap

ChIP DE DE-GATA6-2 800 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 794 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 800 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 800 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 752 bp overlap

Motif ES_0h ES_0h-GATA6_MA1104.3 8 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 800 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 800 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 700 bp overlap

ChIP foregut GSE117136.GATA6.foregut 227 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 237 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 220 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 182 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 266 bp overlap

GRHL2 3 datasets

Motif ES_0h ES_0h-GRHL2_MA1105.3 8 bp overlap

ChIP MCF-7 GSE109820.GRHL2.MCF-7 165 bp overlap

ChIP MCF-7-WS8_VEH GSE113092.GRHL2.MCF-7-WS8_VEH 487 bp overlap

Gata3 1 dataset

Motif ES_0h ES_0h-Gata3_MA0037.5 8 bp overlap

HAND2 1 dataset

Motif ES_0h ES_0h-HAND2_MA1638.2 6 bp overlap

HDAC2 1 dataset

ChIP H1 ENCFF939VKA 237 bp overlap

HMBOX1 1 dataset

Motif ES_0h ES_0h-HMBOX1_MA0895.2 7 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 391 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 282 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 742 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 716 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 405 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 570 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 450 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 693 bp overlap

Motif ES_0h ES_0h-Lhx3_MA0135.2 12 bp overlap

ChIP WA01 ENCSR000EUP.MAX.WA01 212 bp overlap

MORC2 1 dataset

ChIP H9 GSE95374.MORC2.H9 360 bp overlap

MYBL2 2 datasets

ChIP WTC11 ENCFF166TKT 483 bp overlap

ChIP WTC11 ENCFF166TKT 281 bp overlap

Motif ES_0h ES_0h-MYF5_MA1641.2 8 bp overlap

Mecom 1 dataset

Motif ES_0h ES_0h-Mecom_MA0029.2 11 bp overlap

NANOG 11 datasets

ChIP GM23338 ENCFF065NZG 102 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 198 bp overlap

ChIP H1 ENCFF747ZPQ 200 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 516 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 541 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 296 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 800 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 469 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 380 bp overlap

ChIP hESC GSE18292.NANOG.hESC 342 bp overlap

ChIP hESC GSE20650.NANOG.hESC 250 bp overlap

NEUROD1 1 dataset

Motif ES_0h ES_0h-NEUROD1_MA1109.2 8 bp overlap

Neurod2 2 datasets

Motif ES_0h ES_0h-Neurod2_MA0668.3 8 bp overlap

Motif ES_0h ES_0h-Neurod2_MA1993.2 6 bp overlap

ChIP WTC11 ENCFF634NAO 245 bp overlap

Olig2 1 dataset

Motif ES_0h ES_0h-Olig2_MA1997.2 6 bp overlap

POLR2A 1 dataset

ChIP H1 ENCFF566JSR 625 bp overlap

POU2F1::SOX2 1 dataset

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU3F1 1 dataset

Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap

POU3F3 1 dataset

Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap

POU5F1 13 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 722 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 474 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 242 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 374 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 138 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 198 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 203 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 204 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 368 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 293 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 203 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 739 bp overlap

Pou5f1::Sox2 1 dataset

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

Ptf1A 1 dataset

Motif ES_0h ES_0h-Ptf1A_MA1619.2 8 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 137 bp overlap

SAP30 1 dataset

ChIP WA01 ENCSR000ATR.SAP30.WA01 286 bp overlap

Motif ES_0h ES_0h-SIX2_MA1119.2 11 bp overlap

SMAD2 1 dataset

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 222 bp overlap

SMAD2-3 4 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 218 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 635 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 800 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 725 bp overlap

SMAD2_3 6 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 747 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 800 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 800 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 800 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 795 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 406 bp overlap

SMAD3 3 datasets

ChIP BG03 GSE21614.SMAD3.BG03 227 bp overlap

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 145 bp overlap

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 138 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 504 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 458 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 413 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 452 bp overlap

SMARCC1 5 datasets

ChIP DE_D1 S10-DE-d1-BAF155-exp1 261 bp overlap

ChIP DE_D1 S15-DE-d1-BAF155-exp1 795 bp overlap

ChIP ESC S25-ESC-d0-BAF155-exp1 315 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 422 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 499 bp overlap

SOX17 2 datasets

ChIP DE_D2 DED2-SOX17_Batch_II 244 bp overlap

ChIP DE_D2 DED2-SOX17_Batch_II 231 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 800 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 149 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 397 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 438 bp overlap

ChIP WTC11 ENCFF688PEU 457 bp overlap

Motif ES_0h ES_0h-SP4_MA0685.2 9 bp overlap

Motif ES_0h ES_0h-SP5_MA1965.2 6 bp overlap

STAT3 1 dataset

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 260 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 204 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 485 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 122 bp overlap

TBX20 1 dataset

Motif ES_0h ES_0h-TBX20_MA0689.1 11 bp overlap

TCF12 2 datasets

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 238 bp overlap

ChIP NPC GSE154479.TCF3.NPC 425 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 355 bp overlap

TEAD4 3 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 385 bp overlap

ChIP H1 ENCFF778PAX 245 bp overlap

ChIP hESC GSE99202.TEAD4.hESC 397 bp overlap

Motif ES_0h ES_0h-TP53_MA0106.3 18 bp overlap

TRPS1 1 dataset

Motif ES_0h ES_0h-TRPS1_MA1970.2 8 bp overlap

Tcf12 1 dataset

Motif ES_0h ES_0h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif ES_0h ES_0h-Twist2_MA0633.3 6 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 264 bp overlap

ZBTB18 1 dataset

Motif ES_0h ES_0h-ZBTB18_MA0698.2 11 bp overlap

ZMAT4 1 dataset

ChIP WTC11 ENCFF608UXZ 241 bp overlap

ZNF184 1 dataset

ChIP WTC11 ENCFF352POG 394 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 405 bp overlap

ZNF263 1 dataset

Motif ES_0h ES_0h-ZNF263_MA0528.3 7 bp overlap

ZNF331 1 dataset

ChIP GM23338 ENCFF410NSZ 225 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 324 bp overlap

ZNF558 1 dataset

Motif ES_0h ES_0h-ZNF558_MA2335.1 29 bp overlap

ZNF708 1 dataset

Motif ES_0h ES_0h-ZNF708_MA1730.2 9 bp overlap

Zfp335 1 dataset

Motif ES_0h ES_0h-Zfp335_MA2002.2 7 bp overlap

Motif ES_0h ES_0h-Zic2_MA1629.2 9 bp overlap