chrX:71,053,141–71,053,663

chrX : 71,053,141 – 71,053,663

522 bp 90 TFs 6 linked genes

This 522 bp open chromatin element is linked to 6 target genes and is bound by 90 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SNX12		14.9 kb	Distal	Multiome
MED12		65.2 kb	Distal	Multiome
NLGN3		91.4 kb	Distal	Multiome
SLC7A3		122.3 kb	Distal	Multiome
ZMYM3		200.7 kb	Distal	Multiome
NONO		230.2 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

90 transcription factors

ChIP GM01310_3MC GSE116632.AHR.GM01310_3MC 204 bp overlap

ChIP GM01310_DMSO GSE116632.AHR.GM01310_DMSO 188 bp overlap

ASH2L 1 dataset

ChIP WA01 ENCSR850KIP.ASH2L.WA01 522 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 230 bp overlap

BCL11A 5 datasets

ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 95 bp overlap

ChIP CD34_Day7_60min GSE104676.BCL11A.CD34_Day7_60min 97 bp overlap

ChIP CD34_Day9_60min GSE104676.BCL11A.CD34_Day9_60min 68 bp overlap

ChIP CD34_Day9_90min GSE104676.BCL11A.CD34_Day9_90min 89 bp overlap

ChIP CD34_Day9_90min GSE104676.BCL11A.CD34_Day9_90min 69 bp overlap

ChIP GM12878 ENCSR000BNQ.BCL3.GM12878 146 bp overlap

ChIP SU-DHL-4 GSE119038.BCL6.SU-DHL-4 485 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 196 bp overlap

BRD3 2 datasets

ChIP MV4-11_DMSO GSE120715.BRD3.MV4-11_DMSO 163 bp overlap

ChIP MV4-11_IBET151_50nM GSE120715.BRD3.MV4-11_IBET151_50nM 113 bp overlap

BRD4 20 datasets

ChIP CD4_Th1_BAY GSE62482.BRD4.CD4_Th1_BAY 114 bp overlap

ChIP CLL_patient1_4h_CpG GSE109411.BRD4.CLL_patient1_4h_CpG 134 bp overlap

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 225 bp overlap

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 352 bp overlap

ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 363 bp overlap

ChIP KOPT-K1 GSE54379.BRD4.KOPT-K1 210 bp overlap

ChIP KOPT-K1_E GSE54379.BRD4.KOPT-K1_E 319 bp overlap

ChIP MM1-S GSE43743.BRD4.MM1-S 296 bp overlap

ChIP MM1-S_DMSO GSE42161.BRD4.MM1-S_DMSO 229 bp overlap

ChIP MM1-S_JQ1_150NM GSE49224.BRD4.MM1-S_JQ1_150NM 198 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.BRD4.MM1-S_JQ1_500NM 267 bp overlap

ChIP MM1-S_JQ1_50NM GSE42355.BRD4.MM1-S_JQ1_50NM 218 bp overlap

ChIP MM1-S_JQ1_5NM GSE42355.BRD4.MM1-S_JQ1_5NM 314 bp overlap

ChIP MM1-S_JQ1_5UM GSE42355.BRD4.MM1-S_JQ1_5UM 185 bp overlap

ChIP MV4-11-B_BI00894999_100nM_4h GSE101821.BRD4.MV4-11-B_BI00894999_100nM_4h 186 bp overlap

ChIP MV4-11-B_DMSO GSE101821.BRD4.MV4-11-B_DMSO 120 bp overlap

ChIP MV4-11_DMSO GSE120715.BRD4.MV4-11_DMSO 177 bp overlap

ChIP MV4-11_IBET151_50nM GSE120715.BRD4.MV4-11_IBET151_50nM 100 bp overlap

ChIP MV4-11_SGC GSE71776.BRD4.MV4-11_SGC 144 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

ChIP H9_Activin GSE94418.BRF1.H9_Activin 164 bp overlap

CDK9 4 datasets

ChIP MM1-S_DMSO GSE42161.CDK9.MM1-S_DMSO 403 bp overlap

ChIP MM1-S_JQ1_5000NM GSE49224.CDK9.MM1-S_JQ1_5000NM 225 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.CDK9.MM1-S_JQ1_500NM 331 bp overlap

ChIP MM1-S_JQ1_50NM GSE49224.CDK9.MM1-S_JQ1_50NM 277 bp overlap

CEBPA 4 datasets

ChIP Kasumi-1 GSE102697.CEBPA.Kasumi-1 180 bp overlap

ChIP Kasumi-1_CEBPA-ER GSE102697.CEBPA.Kasumi-1_CEBPA-ER 137 bp overlap

ChIP Kasumi-1_CEBPA-ER_E2 GSE102697.CEBPA.Kasumi-1_CEBPA-ER_E2 236 bp overlap

ChIP Kasumi-1_SIRUNX1ETO GSE60130.CEBPA.Kasumi-1_SIRUNX1ETO 181 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 93 bp overlap

CHD2 3 datasets

ChIP GM12878 ENCFF697XCL 381 bp overlap

ChIP H1 ENCFF991MKH 331 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 327 bp overlap

CREB1 5 datasets

ChIP GM12878 ENCFF870CVH 318 bp overlap

ChIP GM12878 ENCSR000BUF.CREB1.GM12878 257 bp overlap

ChIP GM23338 ENCFF432ZEW 271 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 177 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 179 bp overlap

CTCF 7 datasets

ChIP GM12868 ENCSR000DRI.CTCF.GM12868 141 bp overlap

ChIP GM12869 ENCSR000DRJ.CTCF.GM12869 98 bp overlap

ChIP HAP1_WT GSE126634.CTCF.HAP1_WT 175 bp overlap

ChIP Kasumi-1_ctrl GSE121280.CTCF.Kasumi-1_ctrl 119 bp overlap

ChIP WA01_NEUR GSE52457.CTCF.WA01_NEUR 281 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 328 bp overlap

ChIP hiPSC_IIIB12 GSE106870.CTCF.hiPSC_IIIB12 130 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 519 bp overlap

ChIP BLaER1 ENCFF335XTP 251 bp overlap

ChIP MM1-S GSE80661.E2F1.MM1-S 338 bp overlap

E2F4 2 datasets

ChIP GM12878 ENCFF509WLQ 167 bp overlap

ChIP GM12878 ENCSR000DYY.E2F4.GM12878 258 bp overlap

ChIP T-HESCs GSE141063.EGR1.T-HESCs 254 bp overlap

ELF1 2 datasets

ChIP GM12878 ENCFF432UGA 200 bp overlap

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 323 bp overlap

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 293 bp overlap

ETS1 3 datasets

ChIP cardiomyocyte_D14 GSE129986.ETS1.cardiomyocyte_D14 343 bp overlap

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 336 bp overlap

ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 324 bp overlap

ChIP GM12878 ENCFF157FTE 261 bp overlap

ChIP GM12878 ENCSR000EYZ.FOS.GM12878 241 bp overlap

FOXO1 1 dataset

ChIP CD34 GSE80773.FOXO1.CD34 58 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 245 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 290 bp overlap

JMJD1C 1 dataset

ChIP Kasumi-1 GSE63484.JMJD1C.Kasumi-1 89 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 136 bp overlap

KLF10 1 dataset

Motif DE_12h DE_12h-KLF10_MA1511.2 9 bp overlap

KLF12 1 dataset

Motif DE_12h DE_12h-KLF12_MA0742.2 9 bp overlap

ChIP Kasumi-1_siRE GSE121280.LDB1.Kasumi-1_siRE 84 bp overlap

ChIP P493-6 GSE36354.MAX.P493-6 361 bp overlap

MED1 4 datasets

ChIP GM12878 GSE93080.MED1.GM12878 286 bp overlap

ChIP MM1-S_JQ1_500NM GSE42355.MED1.MM1-S_JQ1_500NM 427 bp overlap

ChIP MM1-S_JQ1_50NM GSE49224.MED1.MM1-S_JQ1_50NM 199 bp overlap

ChIP MM1-S_JQ1_5NM GSE49224.MED1.MM1-S_JQ1_5NM 371 bp overlap

MLLT1_FKB 1 dataset

ChIP MV4-11 GSE82116.MLLT1_FKB.MV4-11 186 bp overlap

MXI1 5 datasets

ChIP GM12878 ENCFF666NJR 431 bp overlap

ChIP GM12878 ENCSR000DZI.MXI1.GM12878 202 bp overlap

ChIP H1 ENCFF963FZS 337 bp overlap

ChIP IMR-90 ENCSR000EFE.MXI1.IMR-90 125 bp overlap

ChIP WA01 ENCSR000EBR.MXI1.WA01 229 bp overlap

ChIP CD34 GSE85488.MYC.CD34 265 bp overlap

ChIP MM1-S_DMSO GSE36354.MYC.MM1-S_DMSO 237 bp overlap

NANOG 1 dataset

ChIP HUES-8 GSE109524.NANOG.HUES-8 427 bp overlap

NCAPH2 1 dataset

ChIP IMR-90_Triptolide-5min GSE118494.NCAPH2.IMR-90_Triptolide-5min 304 bp overlap

NCOA3 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 123 bp overlap

ChIP ProEs GSE59087.NFE2.ProEs 101 bp overlap

ChIP GM12878 ENCSR000DNN.NFYA.GM12878 253 bp overlap

NFYB 7 datasets

ChIP GM12878 ENCFF474DNH 405 bp overlap

ChIP GM12878 ENCSR000DNM.NFYB.GM12878 514 bp overlap

ChIP HeLa-S3 ENCSR000DNR.NFYB.HeLa-S3 168 bp overlap

ChIP K-562 ENCSR000EGQ.NFYB.K-562 354 bp overlap

ChIP K-562 GSE26439.NFYB.K-562 201 bp overlap

ChIP K562 ENCFF709RXX 317 bp overlap

ChIP WTC11 ENCFF751ZTQ 338 bp overlap

NIPBL 1 dataset

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 186 bp overlap

ChIP GM12878 ENCFF392NLB 303 bp overlap

PATZ1 1 dataset

Motif DE_12h DE_12h-PATZ1_MA1961.2 11 bp overlap

PAX3-FOXO1 1 dataset

ChIP Hs-352-Sk_PAX3-FOXO1-vector GSE83725.PAX3-FOXO1.Hs-352-Sk_PAX3-FOXO1-vector 108 bp overlap

PAX5 2 datasets

ChIP GM12878 ENCSR000BHD.PAX5.GM12878 224 bp overlap

ChIP GM12878 ENCSR000BHJ.PAX5.GM12878 188 bp overlap

PBX3 2 datasets

ChIP GM12878 ENCFF285BQQ 142 bp overlap

ChIP GM12878 ENCSR000BGR.PBX3.GM12878 224 bp overlap

PKNOX1 5 datasets

ChIP GM12878 ENCFF589FCY 363 bp overlap

ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 459 bp overlap

ChIP HEK293T ENCFF174WDB 296 bp overlap

ChIP HEK293T ENCSR233FAG.PKNOX1.HEK293T 265 bp overlap

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 176 bp overlap

POLR2A 9 datasets

ChIP GM12878 ENCFF263VRI 410 bp overlap

ChIP GM12878 ENCFF521FXC 351 bp overlap

ChIP GM18505 ENCFF311CYB 413 bp overlap

ChIP GM18526 ENCFF599EPS 392 bp overlap

ChIP GM18951 ENCFF079KKO 204 bp overlap

ChIP GM19099 ENCFF726IBN 392 bp overlap

ChIP H1 ENCFF566JSR 173 bp overlap

ChIP erythroblast ENCFF498VMR 522 bp overlap

ChIP spleen ENCFF706IUS 333 bp overlap

POU5F1 4 datasets

ChIP BG03 GSE21614.POU5F1.BG03 294 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 295 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 456 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR362VCG.POU5F1.neuron_bipolar_doxy_4d 131 bp overlap

PPARG 2 datasets

ChIP HUVEC-C_DMSO_HYPO GSE50144.PPARG.HUVEC-C_DMSO_HYPO 173 bp overlap

ChIP HUVEC-C_PPARG_HYPO GSE50144.PPARG.HUVEC-C_PPARG_HYPO 170 bp overlap

RAD21 1 dataset

ChIP peripheral-blood-neutrophil_PMA-1 GSE126755.RAD21.peripheral-blood-neutrophil_PMA-1 217 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 217 bp overlap

ChIP MUTUL GSE75503.RBPJ.MUTUL 204 bp overlap

ChIP CD4_Th1_BAY GSE62482.RELA.CD4_Th1_BAY 122 bp overlap

RELB 2 datasets

ChIP GM12878 ENCFF217ADF 430 bp overlap

ChIP GM12878 ENCSR387QUV.RELB.GM12878 283 bp overlap

RUNX1T1 3 datasets

ChIP CD34 GSE80773.RUNX1T1.CD34 272 bp overlap

ChIP Kasumi-1 GSE115115.RUNX1T1.Kasumi-1 295 bp overlap

ChIP Kasumi-1 GSE102697.RUNX1T1.Kasumi-1 64 bp overlap

SAP30 3 datasets

ChIP H1 ENCFF149IOE 428 bp overlap

ChIP WA01 ENCSR000ATR.SAP30.WA01 399 bp overlap

ChIP WA01 ENCSR000ATR.SAP30.WA01 65 bp overlap

SIN3A 6 datasets

ChIP GM12878 ENCFF238GUI 262 bp overlap

ChIP GM12878 ENCSR000DYX.SIN3A.GM12878 239 bp overlap

ChIP H1 ENCFF042ZSL 457 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 522 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 170 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 291 bp overlap

ChIP H1 ENCFF942SOJ 195 bp overlap

SMAD2-3 1 dataset

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 388 bp overlap

ChIP HAP1_WaplKO-33 GSE94992.SMC1.HAP1_WaplKO-33 122 bp overlap

ChIP peripheral-blood-neutrophil_Ecoli-1 GSE126755.SMC3.peripheral-blood-neutrophil_Ecoli-1 268 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 397 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 200 bp overlap

Motif DE_12h DE_12h-SP1_MA0079.5 9 bp overlap

ChIP GM12878 ENCFF620LDJ 129 bp overlap

ChIP GM12878 ENCSR000BHK.SP1.GM12878 349 bp overlap

ChIP H1 ENCFF263FUH 318 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 339 bp overlap

ChIP WTC11 ENCFF688PEU 501 bp overlap

ChIP H1 ENCFF903ACN 331 bp overlap

ChIP WA01 ENCSR000BQG.SP2.WA01 268 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 137 bp overlap

SREBP2 2 datasets

ChIP monocyte GSE129202.SREBP2.monocyte 107 bp overlap

ChIP monocyte_TNF GSE129202.SREBP2.monocyte_TNF 388 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 356 bp overlap

STAT3 1 dataset

ChIP SU-DHL-2 GSE50723.STAT3.SU-DHL-2 101 bp overlap

SUPT6H 1 dataset

ChIP HCT-116_Inhibitor GSE130509.SUPT6H.HCT-116_Inhibitor 289 bp overlap

TAF1 3 datasets

ChIP GM12878 ENCSR000BGS.TAF1.GM12878 198 bp overlap

ChIP H1 ENCFF478SZO 384 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 269 bp overlap

TARDBP 1 dataset

ChIP GM12878 ENCSR412QBS.TARDBP.GM12878 129 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 147 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 142 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 104 bp overlap

TEAD1 1 dataset

ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 138 bp overlap

TEAD4 1 dataset

ChIP H1 ENCFF778PAX 245 bp overlap

TFAP2C 1 dataset

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 233 bp overlap

TFDP1 1 dataset

ChIP MM1-S GSE80661.TFDP1.MM1-S 449 bp overlap

TRIM22 1 dataset

ChIP GM12878 ENCSR637QAM.TRIM22.GM12878 81 bp overlap

ZBED4 1 dataset

Motif DE_12h DE_12h-ZBED4_MA2328.1 10 bp overlap

ZBTB33 2 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 443 bp overlap

ChIP K562 ENCFF427SDV 453 bp overlap

ZBTB48 1 dataset

ChIP U2OS_ZBTB48-KO GSE96776.ZBTB48.U2OS_ZBTB48-KO 362 bp overlap

ZBTB7A 1 dataset

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 68 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 149 bp overlap

ZNF143 2 datasets

ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 218 bp overlap

ChIP FLP143HA_T4 GSE39263.ZNF143.FLP143HA_T4 145 bp overlap

Motif DE_12h DE_12h-Zfx_MA0146.3 10 bp overlap