chr19:55,652,138–55,653,078

chr19 : 55,652,138 – 55,653,078

940 bp 105 TFs 11 linked genes

This 940 bp open chromatin element is linked to 11 target genes and is bound by 105 transcription factors.

Linked Genes

11 genes

Gene	Expression	Dist. to TSS	Distance	Link type
U2AF2		2.0 kb	Proximal	Proximity
CCDC106		4.1 kb	Proximal	Proximity
ZNF581		8.5 kb	Proximal	Proximity
ZNF580		10.3 kb	Distal	Multiome
EPN1		22.8 kb	Distal	Multiome
ZNF865		46.8 kb	Distal	Multiome
ZNF579		71.6 kb	Distal	Multiome
NAT14		167.2 kb	Distal	Multiome
ISOC2		190.8 kb	Distal	Multiome
UBE2S		244.6 kb	Distal	Multiome
RPL28		266.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

105 transcription factors

AGO1 4 datasets

ChIP Hep-G2 ENCSR555ZMV.AGO1.Hep-G2 443 bp overlap

ChIP Hep-G2 GSE120104.AGO1.Hep-G2 363 bp overlap

ChIP K-562 ENCSR641BSL.AGO1.K-562 457 bp overlap

ChIP K-562 GSE120104.AGO1.K-562 420 bp overlap

ChIP prostate_cancer-associated-fibroblasts GSE90772.AR.prostate_cancer-associated-fibroblasts 305 bp overlap

ARID4B 3 datasets

ChIP K562 ENCFF791HBV 563 bp overlap

ChIP PC-3 GSE116669.ARID4B.PC-3 247 bp overlap

ChIP PC-3 GSE116669.ARID4B.PC-3 113 bp overlap

ChIP HCT-116 GSE130477.ATF1.HCT-116 270 bp overlap

BCL11A 1 dataset

ChIP MCF-10A ERP003925.BCL11A.MCF-10A 161 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 324 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 188 bp overlap

BRD4 14 datasets

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 677 bp overlap

ChIP CLL_patient2_4h_CpG_BET GSE109411.BRD4.CLL_patient2_4h_CpG_BET 821 bp overlap

ChIP CLL_patient3 GSE109411.BRD4.CLL_patient3 669 bp overlap

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 665 bp overlap

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 87 bp overlap

ChIP CLL_patient3_4h_CpG_BET GSE109411.BRD4.CLL_patient3_4h_CpG_BET 582 bp overlap

ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 650 bp overlap

ChIP CLL_patient4_4h_CpG GSE109411.BRD4.CLL_patient4_4h_CpG 177 bp overlap

ChIP CLL_patient4_4h_CpG_BET GSE109411.BRD4.CLL_patient4_4h_CpG_BET 270 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 253 bp overlap

ChIP HAP1 GSE108387.BRD4.HAP1 98 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 365 bp overlap

ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 489 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 766 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 204 bp overlap

ChIP RH5 GSE155861.CHD4.RH5 220 bp overlap

CREB1 1 dataset

ChIP WA01 ENCSR000BSN.CREB1.WA01 121 bp overlap

CTCF 10 datasets

ChIP DOHH2 ENCSR084RDK.CTCF.DOHH2 144 bp overlap

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP HCT-116 GSE131606.CTCF.HCT-116 431 bp overlap

ChIP HT-1080 GSE135580.CTCF.HT-1080 235 bp overlap

ChIP HT-1080_CBL0137-6h GSE122462.CTCF.HT-1080_CBL0137-6h 207 bp overlap

ChIP T-47D_D538G GSE148277.CTCF.T-47D_D538G 55 bp overlap

ChIP colon_transverse ENCSR102CSD.CTCF.colon_transverse 67 bp overlap

ChIP erythroid GSE67783.CTCF.erythroid 348 bp overlap

ChIP esophagus_squamous-epithelium ENCSR838RUX.CTCF.esophagus_squamous-epithelium 197 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR619IUE.CTCF.neuron_bipolar_doxy_4d 232 bp overlap

CTCFL 1 dataset

ChIP K-562 GSE70764.CTCFL.K-562 248 bp overlap

DNMT3B 2 datasets

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 81 bp overlap

ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 329 bp overlap

E2F6 2 datasets

ChIP H1 ENCFF785DWK 451 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 194 bp overlap

EGR1 2 datasets

ChIP A-375 GSE116190.EGR1.A-375 337 bp overlap

ChIP K-562 ENCSR024CNP.EGR1.K-562 189 bp overlap

ChIP HEK293 ENCFF336LFH 425 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 549 bp overlap

ChIP K-562 GSE23730.ERG.K-562 178 bp overlap

ChIP MCF-7_Fulv GSE115607.ESR1.MCF-7_Fulv 200 bp overlap

ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 274 bp overlap

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 291 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 624 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 830 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 614 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 574 bp overlap

HNRNPK 1 dataset

ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 251 bp overlap

HNRNPLL 2 datasets

ChIP Hep-G2 GSE120104.HNRNPLL.Hep-G2 348 bp overlap

ChIP Hep-G2 ENCSR804HMZ.HNRNPLL.Hep-G2 310 bp overlap

ChIP WA09_heat-shock GSE105028.HSF1.WA09_heat-shock 251 bp overlap

IFNA1 1 dataset

ChIP Huh-7_GFP GSE110511.IFNA1.Huh-7_GFP 680 bp overlap

Motif DE_24h DE_24h-IRF3_MA1418.2 17 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 518 bp overlap

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 788 bp overlap

KDM4A 1 dataset

ChIP WA01 ENCSR000AVC.KDM4A.WA01 202 bp overlap

KDM5B 1 dataset

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 278 bp overlap

KDM6B 1 dataset

ChIP CUTLL1 GSE56694.KDM6B.CUTLL1 320 bp overlap

KLF12 1 dataset

Motif DE_48h DE_48h-KLF12_MA0742.2 9 bp overlap

Motif DE_48h DE_48h-KLF4_MA0039.5 8 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 125 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 192 bp overlap

ChIP H1 ENCFF914VQY 357 bp overlap

ChIP HeLa GSE41006.MBD2.HeLa 110 bp overlap

MED1 5 datasets

ChIP HCT-116 GSE121798.MED1.HCT-116 218 bp overlap

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 348 bp overlap

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 637 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 320 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 499 bp overlap

ChIP 501-mel_K243Q GSE137522.MITF.501-mel_K243Q 243 bp overlap

MYOCD 1 dataset

ChIP A-549 GSE128921.MYOCD.A-549 262 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 240 bp overlap

NCAPH2 2 datasets

ChIP IMR-90_Bethyl275_G GSE118494.NCAPH2.IMR-90_Bethyl275_G 285 bp overlap

ChIP IMR-90_FLAG_OIS GSE118494.NCAPH2.IMR-90_FLAG_OIS 940 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 467 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 424 bp overlap

NUTM1 1 dataset

ChIP embryonic-kidney_induced GSE133122.NUTM1.embryonic-kidney_induced 940 bp overlap

OGG1 4 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 456 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 413 bp overlap

ChIP HEK293_30_min GSE89017.OGG1.HEK293_30_min 406 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 356 bp overlap

PATZ1 1 dataset

Motif DE_48h DE_48h-PATZ1_MA1961.2 11 bp overlap

Motif DE_48h DE_48h-PBX3_MA1114.2 11 bp overlap

PCBP1 2 datasets

ChIP K-562 GSE120104.PCBP1.K-562 419 bp overlap

ChIP K-562 ENCSR052PTN.PCBP1.K-562 373 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 726 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 212 bp overlap

POLR2A 2 datasets

ChIP GM12878 ENCFF521FXC 425 bp overlap

ChIP GM23338 ENCFF450WCS 429 bp overlap

POLR2G 2 datasets

ChIP K562 ENCFF047BLG 760 bp overlap

ChIP K562 ENCFF648YPL 762 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 848 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 311 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 774 bp overlap

PRDM9 1 dataset

Motif DE_48h DE_48h-PRDM9_MA1723.2 20 bp overlap

PRPF4 2 datasets

ChIP K-562 GSE120104.PRPF4.K-562 559 bp overlap

ChIP K-562 ENCSR220YXI.PRPF4.K-562 533 bp overlap

RBM14 1 dataset

ChIP K-562 ENCSR423FCW.RBM14.K-562 237 bp overlap

RBM14,RBM14-RBM4 2 datasets

ChIP K562 ENCFF118FCO 457 bp overlap

ChIP K562 ENCFF118FCO 457 bp overlap

RBM22 1 dataset

ChIP K-562 GSE120104.RBM22.K-562 235 bp overlap

Motif DE_24h DE_24h-RBPJ_MA1116.2 6 bp overlap

ChIP HEK293_TNF-1h GSE75562.RELA.HEK293_TNF-1h 364 bp overlap

ChIP CD4 GSE49570.REST.CD4 161 bp overlap

RNF2 2 datasets

ChIP WA09 GSE105028.RNF2.WA09 261 bp overlap

ChIP WA09_heat-shock GSE105028.RNF2.WA09_heat-shock 301 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 830 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 796 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 788 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 688 bp overlap

SMAD2-3 1 dataset

ChIP HUVEC-C_TGFB1 GSE134556.SMAD2-3.HUVEC-C_TGFB1 258 bp overlap

SMAD2_3 1 dataset

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 269 bp overlap

ChIP DKO GSE131606.SMC1.DKO 245 bp overlap

ChIP peripheral-blood-neutrophil_Ecoli-1 GSE126755.SMC3.peripheral-blood-neutrophil_Ecoli-1 65 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 280 bp overlap

Motif DE_48h DE_48h-SP2_MA0516.3 9 bp overlap

ChIP HEK293 ENCFF181QXT 485 bp overlap

Motif DE_48h DE_48h-SP9_MA1564.2 10 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 744 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 635 bp overlap

SRSF1 1 dataset

ChIP Hep-G2 GSE120104.SRSF1.Hep-G2 322 bp overlap

STAT1::STAT2 2 datasets

Motif DE_24h DE_24h-STAT1STAT2_MA0517.2 13 bp overlap

Motif DE_48h DE_48h-STAT1STAT2_MA0517.2 13 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 113 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 536 bp overlap

SUPT5H 2 datasets

ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 326 bp overlap

ChIP DLD-1_NELFCD-AID GSE144786.SUPT5H.DLD-1_NELFCD-AID 262 bp overlap

Motif DE_24h DE_24h-Spz1_MA0111.1 11 bp overlap

TEAD1 1 dataset

ChIP H69 GSE62274.TEAD1.H69 151 bp overlap

THAP1 1 dataset

Motif DE_48h DE_48h-THAP1_MA0597.3 8 bp overlap

TP63 2 datasets

ChIP breast-organoid GSE113909.TP63.breast-organoid 153 bp overlap

ChIP breast-organoid GSE113909.TP63.breast-organoid 309 bp overlap

TRIM24 1 dataset

ChIP LNCaP-abl_ETOH GSE69331.TRIM24.LNCaP-abl_ETOH 349 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 482 bp overlap

TRIM28 1 dataset

ChIP AF22 GSE84259.TRIM28.AF22 387 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 547 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 685 bp overlap

ZBTB33 3 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 752 bp overlap

ChIP K562 ENCFF427SDV 505 bp overlap

ChIP K562 ENCFF875HLX 480 bp overlap

ZBTB7A 1 dataset

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 300 bp overlap

ZFHX2 1 dataset

ChIP HEK293 ENCFF167TUA 449 bp overlap

ChIP K562 ENCFF536AJO 101 bp overlap

ZKSCAN1 1 dataset

ChIP K-562 ENCSR882ERE.ZKSCAN1.K-562 123 bp overlap

ZNF148 1 dataset

Motif DE_48h DE_48h-ZNF148_MA1653.2 10 bp overlap

ZNF277 1 dataset

ChIP K562 ENCFF448PCD 115 bp overlap

ZNF281 1 dataset

Motif DE_48h DE_48h-ZNF281_MA1630.3 10 bp overlap

ZNF354C 1 dataset

ChIP K562 ENCFF371JMA 98 bp overlap

ZNF479 1 dataset

ChIP HEK293T GSE78099.ZNF479.HEK293T 156 bp overlap

ZNF506 1 dataset

ChIP HEK293T GSE78099.ZNF506.HEK293T 123 bp overlap

ZNF530 1 dataset

Motif DE_24h DE_24h-ZNF530_MA1981.2 14 bp overlap

ZNF680 1 dataset

ChIP HEK293 ENCSR307CKC.ZNF680.HEK293 293 bp overlap

ZNF816 1 dataset

Motif DE_48h DE_48h-ZNF816_MA1719.2 15 bp overlap