NAT14

N-acetyltransferase 14 (putative) | KLP1

Predicted to enable N-acetyltransferase activity. Predicted to be involved in DNA-templated transcription initiation and positive regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Member of: DE-1 DE-1.39

Biological processes 8 terms

DNA-templated transcription initiation (GO:0006352)N-acetyltransferase activity (GO:0008080)N-acetyltransferase activity (GO:0008080)acyltransferase activity, transferring groups other than amino-acyl groups (GO:0016747)membrane (GO:0016020)nucleus (GO:0005634)positive regulation of DNA-templated transcription (GO:0045893)protein binding (GO:0005515)

Expression (TPM)

TFs regulating NAT14 0 TFs

Transcription factors with Perturb-seq knockdown data for NAT14. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = NAT14 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.

TF	Mean coef	Binding	Outlier	TF→Gene link

Rows:

Elements linked to NAT14

Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of NAT14, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.

Element	Dist. to TSS	Link type	TFs
chr19:55,216,490–55,217,227	268.3 kb	Distal (>10kb) Multiome	1077
chr19:55,257,751–55,259,635	226.0 kb	Distal (>10kb) Multiome	1054
chr19:55,279,599–55,280,933	204.9 kb	Distal (>10kb) Multiome	805
chr19:55,283,835–55,284,716	201.2 kb	Distal (>10kb) Multiome	242
chr19:55,301,640–55,302,240	183.3 kb	Distal (>10kb) Multiome	448
chr19:55,338,676–55,340,358	145.7 kb	Distal (>10kb) Multiome	882
chr19:55,340,675–55,341,535	143.8 kb	Distal (>10kb) Multiome	368
chr19:55,353,720–55,354,487	131.1 kb	Distal (>10kb) Multiome	297
chr19:55,369,099–55,370,447	115.2 kb	Distal (>10kb) Multiome	383
chr19:55,383,539–55,384,553	101.3 kb	Distal (>10kb) Multiome	374
chr19:55,384,697–55,386,560	99.5 kb	Distal (>10kb) Multiome	903
chr19:55,406,950–55,408,675	77.2 kb	Distal (>10kb) Multiome	965
chr19:55,452,738–55,453,308	32.1 kb	Distal (>10kb) Multiome	339
chr19:55,460,784–55,462,230	23.4 kb	Distal (>10kb) Multiome	947
chr19:55,476,048–55,477,307	8.5 kb	Proximal (<10kb) Multiome	1007
chr19:55,481,722–55,482,243	3.0 kb	Proximal (<10kb)	38
chr19:55,484,846–55,485,682	49 bp	At TSS Multiome	594
chr19:55,503,638–55,504,310	18.8 kb	Distal (>10kb) Multiome	710
chr19:55,516,768–55,517,459	31.9 kb	Distal (>10kb) Multiome	583
chr19:55,536,923–55,537,366	52.0 kb	Distal (>10kb) Multiome	180
chr19:55,549,822–55,550,343	64.8 kb	Distal (>10kb) Multiome	396
chr19:55,580,080–55,581,090	95.6 kb	Distal (>10kb) Multiome	718
chr19:55,585,644–55,586,314	100.6 kb	Distal (>10kb) Multiome	370
chr19:55,586,698–55,587,594	102.1 kb	Distal (>10kb) Multiome	463
chr19:55,598,551–55,600,991	115.2 kb	Distal (>10kb) Multiome	1018
chr19:55,604,520–55,606,690	120.1 kb	Distal (>10kb) Multiome	820
chr19:55,623,637–55,625,055	139.3 kb	Distal (>10kb) Multiome	650
chr19:55,640,091–55,641,769	155.8 kb	Distal (>10kb) Multiome	821
chr19:55,642,197–55,644,356	158.3 kb	Distal (>10kb) Multiome	884
chr19:55,647,711–55,648,342	162.9 kb	Distal (>10kb) Multiome	671
chr19:55,652,138–55,653,078	167.2 kb	Distal (>10kb) Multiome	105
chr19:55,653,199–55,656,056	169.5 kb	Distal (>10kb) Multiome	1123
chr19:55,674,767–55,675,613	189.9 kb	Distal (>10kb) Multiome	765

Genome Browser

Genomic view of the NAT14 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.