chr19:19,860,773–19,861,447

chr19 : 19,860,773 – 19,861,447

674 bp 112 TFs 12 linked genes

This 674 bp open chromatin element is linked to 12 target genes and is bound by 112 transcription factors.

Linked Genes

12 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ZNF253		4.4 kb	Proximal	Proximity
ZNF506		39.5 kb	Distal	Multiome
ZNF93		39.7 kb	Distal	Multiome
ENSG00000291177		84.6 kb	Distal	Multiome
ZNF14		128.1 kb	Distal	Multiome
ZNF682		178.3 kb	Distal	Multiome
ZNF101		192.4 kb	Distal	Multiome+HiCAR
ATP13A1		197.5 kb	Distal	Multiome+HiCAR
ZNF90		216.8 kb	Distal	Multiome
GMIP		217.6 kb	Distal	Multiome
LPAR2		233.0 kb	Distal	Multiome
PBX4		242.5 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

112 transcription factors

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 674 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 448 bp overlap

ChIP WTC11 ENCFF354DFT 248 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 670 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 621 bp overlap

BHLHE22 2 datasets

Motif DE_24h DE_24h-BHLHE22_MA1635.2 6 bp overlap

Motif DE_72h DE_72h-BHLHE22_MA1635.2 6 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 307 bp overlap

BRD3 2 datasets

ChIP HUVEC-C GSE60171.BRD3.HUVEC-C 222 bp overlap

ChIP MV4-11_IBET151_500nM GSE120715.BRD3.MV4-11_IBET151_500nM 134 bp overlap

BRD4 11 datasets

ChIP CLL_patient3 GSE109411.BRD4.CLL_patient3 474 bp overlap

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 503 bp overlap

ChIP CLL_patient4 GSE109411.BRD4.CLL_patient4 520 bp overlap

ChIP CLL_patient4_4h_CpG GSE109411.BRD4.CLL_patient4_4h_CpG 469 bp overlap

ChIP KOPT-K1 GSE54379.BRD4.KOPT-K1 271 bp overlap

ChIP SEM GSE83671.BRD4.SEM 280 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 467 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 140 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 436 bp overlap

ChIP H9_Activin GSE94418.BRF1.H9_Activin 170 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 298 bp overlap

ChIP WA01 ENCSR000AQK.CHD1.WA01 405 bp overlap

CHD2 2 datasets

ChIP H1 ENCFF991MKH 331 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 131 bp overlap

CREB1 3 datasets

ChIP H1 ENCFF955PMP 321 bp overlap

ChIP WTC11 ENCFF297VCI 318 bp overlap

ChIP WTC11 ENCFF297VCI 371 bp overlap

ChIP WTC11 ENCFF209ZUE 336 bp overlap

CTBP1 2 datasets

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 293 bp overlap

ChIP K562 ENCFF403WPG 486 bp overlap

Motif DE_24h DE_24h-CTCF_MA0139.2 15 bp overlap

CTNNB1 1 dataset

ChIP hiPSC_D2 GSE132532.CTNNB1.hiPSC_D2 579 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 385 bp overlap

ChIP BLaER1 ENCFF460KDD 65 bp overlap

DUX4 3 datasets

Motif DE_24h DE_24h-DUX4_MA0468.1 11 bp overlap

Motif DE_60h DE_60h-DUX4_MA0468.1 11 bp overlap

Motif DE_72h DE_72h-DUX4_MA0468.1 11 bp overlap

Motif DE_24h DE_24h-Dux_MA0611.3 11 bp overlap

Motif DE_60h DE_60h-Dux_MA0611.3 11 bp overlap

Motif DE_72h DE_72h-Dux_MA0611.3 11 bp overlap

ChIP WTC11 ENCFF994SXO 309 bp overlap

E2F5 2 datasets

ChIP WTC11 ENCFF449LLF 307 bp overlap

ChIP WTC11 ENCFF449LLF 491 bp overlap

E2F6 8 datasets

ChIP H1 ENCFF785DWK 446 bp overlap

ChIP K-562 ENCSR000EWJ.E2F6.K-562 251 bp overlap

ChIP K-562 ENCSR000BLI.E2F6.K-562 76 bp overlap

ChIP K-562 ENCSR000EWJ.E2F6.K-562 143 bp overlap

ChIP K562 ENCFF136LTS 200 bp overlap

ChIP K562 ENCFF136LTS 325 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 99 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 195 bp overlap

ChIP GM12878 ENCSR000BMB.ELF1.GM12878 228 bp overlap

ELF4 2 datasets

Motif DE_24h DE_24h-ELF4_MA0641.1 12 bp overlap

Motif DE_72h DE_72h-ELF4_MA0641.1 12 bp overlap

ChIP WTC11 ENCFF812SCD 437 bp overlap

ChIP SU-DHL-5 GSE45982.EZH2.SU-DHL-5 64 bp overlap

FIGLA 2 datasets

Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

ChIP K-562 ENCSR000FAI.FOS.K-562 167 bp overlap

ChIP K562 ENCFF951GBI 265 bp overlap

FOXA1 1 dataset

ChIP breast-cancer_heregulin GSE101407.FOXA1.breast-cancer_heregulin 328 bp overlap

FOXJ2::ELF1 2 datasets

Motif DE_24h DE_24h-FOXJ2ELF1_MA1952.2 11 bp overlap

Motif DE_72h DE_72h-FOXJ2ELF1_MA1952.2 11 bp overlap

FOXP4 1 dataset

ChIP WTC11 ENCFF708TAF 377 bp overlap

GATA4 5 datasets

Motif DE_24h DE_24h-GATA4_MA0482.3 8 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 315 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 407 bp overlap

GATA5 3 datasets

Motif DE_24h DE_24h-GATA5_MA0766.3 8 bp overlap

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap

GATA6 3 datasets

Motif DE_24h DE_24h-GATA6_MA1104.3 8 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

GTF2F1 2 datasets

ChIP H1 ENCFF399TGL 281 bp overlap

ChIP WA01 ENCSR000EBP.GTF2F1.WA01 294 bp overlap

Gata3 3 datasets

Motif DE_24h DE_24h-Gata3_MA0037.5 8 bp overlap

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

HDAC2 2 datasets

ChIP WA01 ENCSR000AVB.HDAC2.WA01 173 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 211 bp overlap

HMGXB4 2 datasets

ChIP WTC11 ENCFF962POR 360 bp overlap

ChIP WTC11 ENCFF962POR 621 bp overlap

HNRNPLL 3 datasets

ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 424 bp overlap

ChIP K-562 GSE120104.HNRNPLL.K-562 263 bp overlap

ChIP K562 ENCFF541ZGX 468 bp overlap

Motif DE_60h DE_60h-Hmx2_MA0897.2 15 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 461 bp overlap

ChIP CD4 GSE116695.JUNB.CD4 187 bp overlap

ChIP H1 ENCFF468JZD 231 bp overlap

KDM4A 2 datasets

ChIP H1 ENCFF078LED 503 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 394 bp overlap

KDM4C 1 dataset

ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 269 bp overlap

KDM5B 1 dataset

ChIP Hep-G2 ENCSR227MRE.KDM5B.Hep-G2 176 bp overlap

KLF13 1 dataset

Motif DE_24h DE_24h-KLF13_MA0657.2 17 bp overlap

KLF3 2 datasets

Motif DE_24h DE_24h-KLF3_MA1516.2 10 bp overlap

Motif DE_60h DE_60h-KLF3_MA1516.2 10 bp overlap

KMT2A 1 dataset

ChIP SEM GSE83671.KMT2A.SEM 291 bp overlap

L3MBTL2 3 datasets

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 454 bp overlap

ChIP K562 ENCFF320EQC 332 bp overlap

ChIP K562 ENCFF320EQC 151 bp overlap

ChIP CD4_Th1 GSE72266.MAF.CD4_Th1 214 bp overlap

ChIP H1 ENCFF914VQY 236 bp overlap

ChIP H1 ENCFF914VQY 357 bp overlap

ChIP WTC11 ENCFF223QFY 334 bp overlap

ChIP K562 ENCFF140CEX 346 bp overlap

NFATC3 1 dataset

Motif DE_72h DE_72h-NFATC3_MA0625.3 6 bp overlap

ChIP K-562 ENCSR796ITY.NFIC.K-562 231 bp overlap

NFIL3 3 datasets

Motif DE_24h DE_24h-NFIL3_MA0025.3 9 bp overlap

Motif DE_60h DE_60h-NFIL3_MA0025.3 9 bp overlap

Motif DE_72h DE_72h-NFIL3_MA0025.3 9 bp overlap

NFYA 7 datasets

Motif DE_24h DE_24h-NFYA_MA0060.4 8 bp overlap

Motif DE_24h DE_24h-NFYA_MA0060.4 8 bp overlap

Motif DE_60h DE_60h-NFYA_MA0060.4 8 bp overlap

Motif DE_72h DE_72h-NFYA_MA0060.4 8 bp overlap

Motif DE_72h DE_72h-NFYA_MA0060.4 8 bp overlap

ChIP K-562 ENCSR000EGR.NFYA.K-562 163 bp overlap

ChIP K562 ENCFF666BET 317 bp overlap

NFYB 5 datasets

ChIP Hep-G2 ENCSR935GZV.NFYB.Hep-G2 212 bp overlap

ChIP HepG2 ENCFF174VYX 362 bp overlap

ChIP K-562 ENCSR000EGQ.NFYB.K-562 302 bp overlap

ChIP K562 ENCFF709RXX 234 bp overlap

ChIP WTC11 ENCFF751ZTQ 228 bp overlap

NFYC 6 datasets

Motif DE_24h DE_24h-NFYC_MA1644.2 7 bp overlap

Motif DE_24h DE_24h-NFYC_MA1644.2 7 bp overlap

Motif DE_60h DE_60h-NFYC_MA1644.2 7 bp overlap

Motif DE_72h DE_72h-NFYC_MA1644.2 7 bp overlap

Motif DE_72h DE_72h-NFYC_MA1644.2 7 bp overlap

ChIP Hep-G2 ENCSR569ARC.NFYC.Hep-G2 186 bp overlap

NOTCH1 1 dataset

ChIP HPBALL GSE39263.NOTCH1.HPBALL 230 bp overlap

Neurod2 2 datasets

Motif DE_24h DE_24h-Neurod2_MA1993.2 6 bp overlap

Motif DE_72h DE_72h-Neurod2_MA1993.2 6 bp overlap

Nfatc1 1 dataset

Motif DE_72h DE_72h-Nfatc1_MA0624.3 6 bp overlap

ChIP HEK293 GSE89017.OGG1.HEK293 295 bp overlap

Olig2 2 datasets

Motif DE_24h DE_24h-Olig2_MA1997.2 6 bp overlap

Motif DE_72h DE_72h-Olig2_MA1997.2 6 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 275 bp overlap

ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 170 bp overlap

PHF8 2 datasets

ChIP H1 ENCFF427UFV 366 bp overlap

ChIP WA01 ENCSR000ATK.PHF8.WA01 542 bp overlap

POLR2A 7 datasets

ChIP GM23338 ENCFF450WCS 347 bp overlap

ChIP GM23338 ENCFF450WCS 339 bp overlap

ChIP H1 ENCFF566JSR 563 bp overlap

ChIP H1 ENCFF770YBQ 471 bp overlap

ChIP H1 ENCFF770YBQ 327 bp overlap

ChIP H1 ENCFF833NJP 461 bp overlap

ChIP spleen ENCFF446ZGT 508 bp overlap

POU5F1 1 dataset

ChIP BG03 GSE21614.POU5F1.BG03 255 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 418 bp overlap

Prdm4 1 dataset

Motif DE_72h DE_72h-Prdm4_MA1647.3 11 bp overlap

RBBP5 1 dataset

ChIP WA01 ENCSR000AQC.RBBP5.WA01 558 bp overlap

RBFOX2 2 datasets

ChIP K-562 ENCSR822LBD.RBFOX2.K-562 453 bp overlap

ChIP K-562 GSE120104.RBFOX2.K-562 457 bp overlap

REST 4 datasets

ChIP H1 ENCFF429RUE 245 bp overlap

ChIP K-562 ENCSR137ZMQ.REST.K-562 235 bp overlap

ChIP K562 ENCFF688UKW 287 bp overlap

ChIP WA01 ENCSR000BHM.REST.WA01 120 bp overlap

RUNX1 1 dataset

ChIP Jurkat GSE85524.RUNX1.Jurkat 306 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 246 bp overlap

SAP30 2 datasets

ChIP H1 ENCFF149IOE 439 bp overlap

ChIP WA01 ENCSR000ATR.SAP30.WA01 218 bp overlap

SIN3A 3 datasets

ChIP H1 ENCFF042ZSL 521 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 50 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 462 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_T48 GSE137168.SNAI2.SMS-CTR_T48 170 bp overlap

SOX10 1 dataset

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX21 1 dataset

Motif DE_60h DE_60h-SOX21_MA0866.1 15 bp overlap

Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap

ChIP H1 ENCFF263FUH 83 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 248 bp overlap

SREBP2 1 dataset

ChIP HCC70 GSE126380.SREBP2.HCC70 207 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 499 bp overlap

Motif DE_60h DE_60h-Sox1_MA0870.1 15 bp overlap

Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 668 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 674 bp overlap

ChIP hESC GSE17917.TAF2.hESC 200 bp overlap

TAF7 2 datasets

ChIP H1 ENCFF061XZZ 337 bp overlap

ChIP WA01 ENCSR000BLU.TAF7.WA01 214 bp overlap

TBP 10 datasets

ChIP H1 ENCFF859IIO 364 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 674 bp overlap

ChIP hESC GSE122298.TBP.hESC 418 bp overlap

ChIP hESC_10h GSE122298.TBP.hESC_10h 353 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 420 bp overlap

ChIP hESC_8h GSE122298.TBP.hESC_8h 401 bp overlap

ChIP hiPSC_WTa_RNase-neg GSE128135.TBP.hiPSC_WTa_RNase-neg 359 bp overlap

ChIP hiPSC_WTa_RNase-pos GSE128135.TBP.hiPSC_WTa_RNase-pos 248 bp overlap

ChIP hiPSC_WTb_RNase-neg GSE128135.TBP.hiPSC_WTb_RNase-neg 382 bp overlap

ChIP hiPSC_WTb_RNase-pos GSE128135.TBP.hiPSC_WTb_RNase-pos 235 bp overlap

ChIP NPC GSE154479.TCF3.NPC 366 bp overlap

TCF4 2 datasets

Motif DE_24h DE_24h-TCF4_MA0830.3 8 bp overlap

Motif DE_72h DE_72h-TCF4_MA0830.3 8 bp overlap

TEAD1 2 datasets

ChIP WTC11 ENCFF502QUV 233 bp overlap

ChIP WTC11 ENCFF502QUV 405 bp overlap

TFCP2 1 dataset

ChIP K562 ENCFF984WXL 331 bp overlap

TRPS1 3 datasets

Motif DE_24h DE_24h-TRPS1_MA1970.2 8 bp overlap

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

Tcf12 2 datasets

Motif DE_24h DE_24h-Tcf12_MA0521.3 6 bp overlap

Motif DE_72h DE_72h-Tcf12_MA0521.3 6 bp overlap

Tfcp2l1 1 dataset

Motif DE_24h DE_24h-Tfcp2l1_MA0145.2 14 bp overlap

Twist2 2 datasets

Motif DE_24h DE_24h-Twist2_MA0633.3 6 bp overlap

Motif DE_72h DE_72h-Twist2_MA0633.3 6 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 294 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 162 bp overlap

ZBTB6 1 dataset

Motif DE_24h DE_24h-ZBTB6_MA1581.2 9 bp overlap

ZEB1 4 datasets

Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ChIP NCI-H1975_resistant GSE106896.ZEB1.NCI-H1975_resistant 396 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR418KUS.ZEB1.neuron_bipolar_doxy_4d 279 bp overlap

ZNF135 1 dataset

Motif DE_24h DE_24h-ZNF135_MA1587.1 14 bp overlap

ZNF184 1 dataset

ChIP WTC11 ENCFF352POG 497 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 319 bp overlap

ZNF317 1 dataset

Motif DE_24h DE_24h-ZNF317_MA1593.2 8 bp overlap

ZNF416 1 dataset

ChIP WTC11 ENCFF407TAZ 271 bp overlap

ZNF550 1 dataset

ChIP Hep-G2 ENCSR198BHH.ZNF550.Hep-G2 200 bp overlap

ZNF687 1 dataset

ChIP HepG2 ENCFF653WIX 421 bp overlap

ZNF737 1 dataset

ChIP Hep-G2 ENCSR127IHN.ZNF737.Hep-G2 295 bp overlap

ZNF75A 3 datasets

Motif DE_24h DE_24h-ZNF75A_MA2097.1 12 bp overlap

Motif DE_48h DE_48h-ZNF75A_MA2097.1 12 bp overlap

Motif DE_60h DE_60h-ZNF75A_MA2097.1 12 bp overlap

Motif DE_24h DE_24h-Zfx_MA0146.3 10 bp overlap

Motif DE_24h DE_24h-Zfx_MA0146.3 10 bp overlap

Motif DE_60h DE_60h-Zfx_MA0146.3 10 bp overlap

Motif DE_72h DE_72h-Zfx_MA0146.3 10 bp overlap