chr14 : 69,050,256 – 69,051,065
809 bp 105 TFs 5 linked genes
This 809 bp open chromatin element is linked to 5 target genes and is bound by 105 transcription factors.
Linked Genes
5 genes
Link type
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ACTN1 71.4 kb Distal Multiome+HiCAR
DCAF5 102.5 kb Distal Multiome
EXD2 140.8 kb Distal Multiome
GALNT16-AS1 141.4 kb Distal Multiome
ZFP36L1 257.6 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr14:69,045,256 – 69,056,065
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
105 transcription factors
Source
Cell type
AR 1 dataset
ChIP PC-3_R1881 GSE54110.AR.PC-3_R1881 161 bp overlap
BRD4 3 datasets
ChIP HUVEC-C GSE53998.BRD4.HUVEC-C 90 bp overlap
ChIP SUM159PT_100nMtrametinib_24h GSE87418.BRD4.SUM159PT_100nMtrametinib_24h 724 bp overlap
ChIP SUM159PT_100nMtrametinib_72h GSE87418.BRD4.SUM159PT_100nMtrametinib_72h 342 bp overlap
CDK8 1 dataset
ChIP myometrium_PT1063 GSE128230.CDK8.myometrium_PT1063 58 bp overlap
CEBPB 1 dataset
ChIP HFOB_DIFF GSE82295.CEBPB.HFOB_DIFF 297 bp overlap
CHD7 1 dataset
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 441 bp overlap
ELL2 1 dataset
ChIP HeLa_DOX GSE40632.ELL2.HeLa_DOX 202 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 269 bp overlap
EP300 1 dataset
ChIP hESC GSE17917.EP300.hESC 295 bp overlap
ESRRA 1 dataset
Motif DE_72h DE_72h-ESRRA_MA0592.4 9 bp overlap
ETV5::DRGX 1 dataset
Motif DE_72h DE_72h-ETV5DRGX_MA1944.2 12 bp overlap
Elf5 1 dataset
Motif DE_72h DE_72h-Elf5_MA0136.4 8 bp overlap
Esrrg 1 dataset
Motif DE_72h DE_72h-Esrrg_MA0643.2 9 bp overlap
FOSL1::JUND 1 dataset
Motif DE_72h DE_72h-FOSL1JUND_MA1143.2 9 bp overlap
FOSL2::JUN 1 dataset
Motif DE_72h DE_72h-FOSL2JUN_MA1131.2 10 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 745 bp overlap
ChIP DE DE-FOXA2-2 802 bp overlap
FOXD3 1 dataset
Motif DE_72h DE_72h-FOXD3_MA0041.3 14 bp overlap
FOXP2 1 dataset
Motif DE_72h DE_72h-FOXP2_MA0593.2 9 bp overlap
FOXP4 1 dataset
ChIP Hep-G2 ENCSR232LLP.FOXP4.Hep-G2 157 bp overlap
GATA2 2 datasets
ChIP ESF GSE108408.GATA2.ESF 284 bp overlap
ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 236 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 678 bp overlap
ChIP DE DE-GATA4-2 778 bp overlap
ChIP foregut GSE117136.GATA4.foregut 479 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 702 bp overlap
GATA6 12 datasets
ChIP DE DE-GATA6-1 716 bp overlap
ChIP DE DE-GATA6-2 757 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 428 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 457 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 260 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 652 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 468 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 440 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 495 bp overlap
ChIP foregut GSE117136.GATA6.foregut 522 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 536 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 400 bp overlap
GRHL1 1 dataset
Motif DE_72h DE_72h-GRHL1_MA0647.2 10 bp overlap
GRHL2 1 dataset
Motif DE_72h DE_72h-GRHL2_MA1105.3 8 bp overlap
HAND2 1 dataset
Motif DE_72h DE_72h-HAND2_MA1638.2 6 bp overlap
HNF1A 1 dataset
ChIP HEE_1 GSE76376.HNF1A.HEE_1 67 bp overlap
HNF1B 2 datasets
ChIP PDAC GSE64557.HNF1B.PDAC 297 bp overlap
ChIP foregut GSE117136.HNF1B.foregut 129 bp overlap
HNF4A 3 datasets
ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 106 bp overlap
Motif DE_72h DE_72h-HNF4A_MA1494.2 14 bp overlap
ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 136 bp overlap
HOXB13 3 datasets
ChIP LNCaP GSE56288.HOXB13.LNCaP 217 bp overlap
ChIP prostate-cancer_PDX_141 GSE130408.HOXB13.prostate-cancer_PDX_141 241 bp overlap
ChIP prostate_P1_T GSE130408.HOXB13.prostate_P1_T 166 bp overlap
Hoxa13 1 dataset
Motif DE_72h DE_72h-Hoxa13_MA0650.4 8 bp overlap
IKZF2 1 dataset
Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap
JMJD1C 1 dataset
ChIP HL-60 GSE63484.JMJD1C.HL-60 158 bp overlap
JUN 2 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 320 bp overlap
ChIP HAEC_TNFa_4h GSE89970.JUN.HAEC_TNFa_4h 148 bp overlap
KAT7 1 dataset
ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 137 bp overlap
KLF4 1 dataset
ChIP HAP1 GSE130417.KLF4.HAP1 363 bp overlap
MAX 1 dataset
ChIP liver ENCFF092GVW 96 bp overlap
MED1 3 datasets
ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 188 bp overlap
ChIP SGBS GSE64233.MED1.SGBS 443 bp overlap
ChIP hMSC-TERT4_osteoblast-D3 GSE113253.MED1.hMSC-TERT4_osteoblast-D3 268 bp overlap
MED12 1 dataset
ChIP myometrium_PT916 GSE128230.MED12.myometrium_PT916 73 bp overlap
MEIS1 1 dataset
Motif DE_72h DE_72h-MEIS1_MA0498.3 5 bp overlap
NANOG 3 datasets
ChIP HUES-8 GSE109524.NANOG.HUES-8 311 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 422 bp overlap
ChIP hESC GSE18292.NANOG.hESC 186 bp overlap
NEUROG2 1 dataset
Motif DE_72h DE_72h-NEUROG2_MA1642.2 7 bp overlap
NR1H2::RXRA 1 dataset
Motif DE_72h DE_72h-NR1H2RXRA_MA0115.1 17 bp overlap
NR2C1 2 datasets
Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap
Motif DE_72h DE_72h-NR2C1_MA1535.2 6 bp overlap
NR2C2 3 datasets
Motif DE_72h DE_72h-NR2C2_MA0504.2 14 bp overlap
Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap
Motif DE_72h DE_72h-NR2C2_MA1536.2 6 bp overlap
NR2F1 3 datasets
Motif DE_72h DE_72h-NR2F1_MA0017.3 12 bp overlap
Motif DE_72h DE_72h-NR2F1_MA1537.2 13 bp overlap
Motif DE_72h DE_72h-NR2F1_MA1537.2 13 bp overlap
NR2F2 3 datasets
Motif DE_72h DE_72h-NR2F2_MA1111.2 7 bp overlap
ChIP liver ENCSR168SMX.NR2F2.liver 506 bp overlap
ChIP liver ENCSR338MMB.NR2F2.liver 216 bp overlap
NR3C1 1 dataset
ChIP SUM159PT GSE152203.NR3C1.SUM159PT 197 bp overlap
NR4A1 1 dataset
Motif DE_72h DE_72h-NR4A1_MA1112.3 8 bp overlap
NR4A2 1 dataset
Motif DE_72h DE_72h-NR4A2_MA0160.3 8 bp overlap
NRF1 1 dataset
ChIP HepG2 ENCFF969ALM 261 bp overlap
Nr1H2 2 datasets
Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap
Motif DE_72h DE_72h-Nr1H2_MA1996.2 6 bp overlap
Nr1H4 2 datasets
Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap
Motif DE_72h DE_72h-Nr1H4_MA1110.3 6 bp overlap
Nr1h3 2 datasets
Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap
Motif DE_72h DE_72h-Nr1h3_MA2337.1 6 bp overlap
Nr1h3::Rxra 1 dataset
Motif DE_72h DE_72h-Nr1h3Rxra_MA0494.2 16 bp overlap
Nr2f6 1 dataset
Motif DE_72h DE_72h-Nr2f6_MA0677.2 13 bp overlap
ONECUT1 1 dataset
Motif DE_72h DE_72h-ONECUT1_MA0679.3 9 bp overlap
PGR 1 dataset
ChIP AB32 GSE31129.PGR.AB32 197 bp overlap
POU2F3 1 dataset
ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 146 bp overlap
POU5F1 4 datasets
ChIP HUES-8 GSE109524.POU5F1.HUES-8 382 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 488 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 453 bp overlap
ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 214 bp overlap
PPARA::RXRA 1 dataset
Motif DE_72h DE_72h-PPARARXRA_MA1148.2 17 bp overlap
PPARD 1 dataset
Motif DE_72h DE_72h-PPARD_MA1550.2 14 bp overlap
PPARG 1 dataset
ChIP Hep-G2 ENCSR130VQL.PPARG.Hep-G2 164 bp overlap
PRDM9 1 dataset
Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap
Ppara 1 dataset
Motif DE_72h DE_72h-Ppara_MA2338.1 7 bp overlap
Pparg::Rxra 1 dataset
Motif DE_72h DE_72h-PpargRxra_MA0065.3 13 bp overlap
Ptf1A 1 dataset
Motif DE_72h DE_72h-Ptf1A_MA1618.2 9 bp overlap
RAD21 1 dataset
ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 374 bp overlap
RBM22 1 dataset
ChIP HepG2 ENCFF292RVQ 330 bp overlap
RELA 3 datasets
ChIP aortic-endothelial-cell_IL1B_D26 GSE139377.RELA.aortic-endothelial-cell_IL1B_D26 169 bp overlap
ChIP aortic-endothelial-cell_IL1B_D38 GSE139377.RELA.aortic-endothelial-cell_IL1B_D38 184 bp overlap
ChIP aortic-endothelial-cell_IL1B_D8 GSE139377.RELA.aortic-endothelial-cell_IL1B_D8 217 bp overlap
REST 1 dataset
ChIP liver ENCFF240FWT 210 bp overlap
RORA 1 dataset
Motif DE_72h DE_72h-RORA_MA0071.1 10 bp overlap
RXR 1 dataset
ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 140 bp overlap
RXRB 1 dataset
Motif DE_72h DE_72h-RXRB_MA0855.1 14 bp overlap
RXRG 1 dataset
Motif DE_72h DE_72h-RXRG_MA0856.1 14 bp overlap
Rarg 1 dataset
Motif DE_72h DE_72h-Rarg_MA0860.1 17 bp overlap
Rxra 1 dataset
Motif DE_72h DE_72h-Rxra_MA0512.2 14 bp overlap
SCRT1 1 dataset
Motif DE_72h DE_72h-SCRT1_MA0743.3 10 bp overlap
SCRT2 1 dataset
Motif DE_72h DE_72h-SCRT2_MA0744.3 10 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 634 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 538 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 434 bp overlap
SMARCA4 3 datasets
ChIP NPC_K755R-siAP GSE122631.SMARCA4.NPC_K755R-siAP 236 bp overlap
ChIP NSC GSE125033.SMARCA4.NSC 387 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 540 bp overlap
SMARCB1 1 dataset
ChIP hiPSC GSE124903.SMARCB1.hiPSC 400 bp overlap
SMARCC1 1 dataset
ChIP hiPSC GSE124903.SMARCC1.hiPSC 359 bp overlap
SOX10 1 dataset
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX13 2 datasets
ChIP Hep-G2 ENCSR445ACU.SOX13.Hep-G2 131 bp overlap
ChIP HepG2 ENCFF062VSQ 170 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 252 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 719 bp overlap
SOX2 4 datasets
ChIP HNSC GSE69479.SOX2.HNSC 345 bp overlap
ChIP hESC GSE18292.SOX2.hESC 97 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 242 bp overlap
ChIP hiPSC_3s2 GSE81899.SOX2.hiPSC_3s2 290 bp overlap
SOX4 1 dataset
Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap
SOX5 1 dataset
ChIP HepG2 ENCFF470KZD 405 bp overlap
SREBP2 1 dataset
ChIP monocyte_TNF GSE129202.SREBP2.monocyte_TNF 150 bp overlap
Sox11 1 dataset
Motif DE_72h DE_72h-Sox11_MA0869.3 8 bp overlap
Sox6 1 dataset
Motif DE_72h DE_72h-Sox6_MA0515.1 10 bp overlap
Spz1 1 dataset
Motif DE_72h DE_72h-Spz1_MA0111.1 11 bp overlap
TAL1 2 datasets
ChIP PRIMA2 GSE33850.TAL1.PRIMA2 87 bp overlap
ChIP PRIMA2 GSE33850.TAL1.PRIMA2 181 bp overlap
TEAD1 1 dataset
ChIP adipocyte GSE140782.TEAD1.adipocyte 192 bp overlap
TEAD4 1 dataset
ChIP MCF-7_BLRP_WT_Veh GSE125594.TEAD4.MCF-7_BLRP_WT_Veh 275 bp overlap
THRA 1 dataset
Motif DE_72h DE_72h-THRA_MA1969.2 18 bp overlap
THRB 3 datasets
Motif DE_72h DE_72h-THRB_MA1574.2 13 bp overlap
Motif DE_72h DE_72h-THRB_MA1574.2 13 bp overlap
Motif DE_72h DE_72h-THRB_MA1576.2 18 bp overlap
TWIST1 1 dataset
Motif DE_72h DE_72h-TWIST1_MA1123.3 8 bp overlap
YY1AP1 1 dataset
ChIP PC-9_1DF GSE131687.YY1AP1.PC-9_1DF 275 bp overlap
ZBTB18 1 dataset
Motif DE_72h DE_72h-ZBTB18_MA0698.2 11 bp overlap
ZNF205 1 dataset
ChIP HEK293T GSE78099.ZNF205.HEK293T 295 bp overlap
ZNF281 1 dataset
Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap
ZNF680 1 dataset
Motif DE_72h DE_72h-ZNF680_MA1729.2 11 bp overlap
ZNF684 1 dataset
Motif DE_72h DE_72h-ZNF684_MA1600.2 14 bp overlap
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