Transcription factors with Perturb-seq knockdown data for GALNT16-AS1. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = GALNT16-AS1 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of GALNT16-AS1, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr14:68,937,585–68,939,538 | 253.4 kb | Distal (>10kb) Multiome | 580 | |
| chr14:68,977,829–68,980,593 | 212.7 kb | Distal (>10kb) Multiome | 919 | |
| chr14:69,050,256–69,051,065 | 141.4 kb | Distal (>10kb) Multiome | 105 | |
| chr14:69,129,353–69,129,859 | 62.6 kb | Distal (>10kb) Multiome | 260 | |
| chr14:69,149,737–69,150,445 | 42.0 kb | Distal (>10kb) Multiome | 70 | |
| chr14:69,151,308–69,153,780 | 40.4 kb | Distal (>10kb) Multiome | 936 | |
| chr14:69,183,867–69,184,070 | 8.0 kb | Proximal (<10kb) | 61 | |
| chr14:69,191,332–69,192,132 | 464 bp | At TSS Multiome | 977 | |
| chr14:69,259,475–69,261,593 | 67.7 kb | Distal (>10kb) Multiome | 477 | |
| chr14:69,397,842–69,399,035 | 206.4 kb | Distal (>10kb) Multiome | 926 | |
| chr14:69,483,950–69,485,210 | 292.5 kb | Distal (>10kb) Multiome | 334 |
Genomic view of the GALNT16-AS1 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.