chr11:6,405,086–6,405,670

chr11 : 6,405,086 – 6,405,670

584 bp 99 TFs 15 linked genes

This 584 bp open chromatin element is linked to 15 target genes and is bound by 99 transcription factors.

Linked Genes

15 genes

Gene	Expression	Dist. to TSS	Distance	Link type
APBB1		153 bp	At TSS	Proximity
TRIM3		68.5 kb	Distal	Multiome
ARFIP2		75.9 kb	Distal	Multiome
TIMM10B		76.1 kb	Distal	Multiome
CAVIN3		84.9 kb	Distal	Multiome
ENSG00000282556		86.2 kb	Distal	Multiome
DNHD1		91.9 kb	Distal	Multiome
CCKBR		145.6 kb	Distal	Multiome
FHIP1B		170.8 kb	Distal	Multiome
RRP8		198.2 kb	Distal	Multiome
ILK		198.4 kb	Distal	Multiome
TAF10		206.8 kb	Distal	Multiome
TPP1		214.0 kb	Distal	Multiome
DCHS1		250.4 kb	Distal	Multiome
MRPL17		277.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

99 transcription factors

ChIP myofibroblast GSE90772.AR.myofibroblast 311 bp overlap

ARNT::HIF1A 1 dataset

Motif ES_0h ES_0h-ARNTHIF1A_MA0259.2 5 bp overlap

ASCL1 1 dataset

Motif ES_0h ES_0h-ASCL1_MA1631.2 9 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 248 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 584 bp overlap

ASXL3 2 datasets

ChIP NCI-H1963_Ab1 GSE145028.ASXL3.NCI-H1963_Ab1 584 bp overlap

ChIP NCI-H1963_Ab2 GSE145028.ASXL3.NCI-H1963_Ab2 244 bp overlap

Ahr::Arnt 1 dataset

Motif ES_0h ES_0h-AhrArnt_MA0006.2 5 bp overlap

BRD4 11 datasets

ChIP COLO-741 GSE73319.BRD4.COLO-741 271 bp overlap

ChIP NCI-H1963_dBET6 GSE145028.BRD4.NCI-H1963_dBET6 584 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 584 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 291 bp overlap

ChIP cortical-interneuron GSE117508.BRD4.cortical-interneuron 159 bp overlap

ChIP cortical-interneuron_KCl-pos GSE117508.BRD4.cortical-interneuron_KCl-pos 297 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 391 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 331 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-pos GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-pos 231 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 468 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 289 bp overlap

ChIP hMSC GSE117084.CBX4.hMSC 171 bp overlap

CREB1 4 datasets

ChIP GM23338 ENCFF432ZEW 305 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 312 bp overlap

ChIP H1 ENCFF955PMP 321 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 211 bp overlap

CREBBP 1 dataset

ChIP retina_Hu33 GSE137311.CREBBP.retina_Hu33 267 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 198 bp overlap

Motif ES_0h ES_0h-EGR1_MA0162.5 10 bp overlap

Motif ES_0h ES_0h-EGR2_MA0472.2 11 bp overlap

Motif ES_0h ES_0h-EGR3_MA0732.2 11 bp overlap

Motif ES_0h ES_0h-EGR4_MA0733.2 11 bp overlap

EP300 4 datasets

ChIP WA01 ENCSR000BKK.EP300.WA01 267 bp overlap

ChIP WA01 ENCSR000AUQ.EP300.WA01 115 bp overlap

ChIP neural ENCSR843ZUP.EP300.neural 584 bp overlap

ChIP neural cell ENCFF442QNK 441 bp overlap

ChIP MCF-7 GSE23730.ERG.MCF-7 198 bp overlap

ETV5::FIGLA 1 dataset

Motif ES_0h ES_0h-ETV5FIGLA_MA1945.2 14 bp overlap

FIGLA 1 dataset

Motif ES_0h ES_0h-FIGLA_MA0820.2 6 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 81 bp overlap

GRHL2 1 dataset

ChIP OVCAR-3 GSE71018.GRHL2.OVCAR-3 140 bp overlap

HDAC2 2 datasets

ChIP WA01 ENCSR000AVB.HDAC2.WA01 247 bp overlap

ChIP WA01 ENCSR000AVB.HDAC2.WA01 224 bp overlap

HIF1A 1 dataset

Motif ES_0h ES_0h-HIF1A_MA1106.2 6 bp overlap

HIVEP1 1 dataset

ChIP Hep-G2 ENCSR697WMX.HIVEP1.Hep-G2 285 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 469 bp overlap

ChIP WA01 ENCSR000BKP.JUND.WA01 98 bp overlap

KDM4C 1 dataset

ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 173 bp overlap

Motif ES_0h ES_0h-KLF1_MA0493.3 8 bp overlap

KLF10 1 dataset

Motif ES_0h ES_0h-KLF10_MA1511.2 9 bp overlap

KLF11 1 dataset

Motif ES_0h ES_0h-KLF11_MA1512.2 10 bp overlap

KLF12 1 dataset

Motif ES_0h ES_0h-KLF12_MA0742.2 9 bp overlap

KLF13 1 dataset

Motif ES_0h ES_0h-KLF13_MA0657.2 17 bp overlap

KLF14 1 dataset

Motif ES_0h ES_0h-KLF14_MA0740.2 9 bp overlap

KLF16 1 dataset

Motif ES_0h ES_0h-KLF16_MA0741.1 11 bp overlap

Motif ES_0h ES_0h-KLF2_MA1515.2 8 bp overlap

Motif ES_0h ES_0h-KLF3_MA1516.2 10 bp overlap

Motif ES_0h ES_0h-KLF6_MA1517.2 9 bp overlap

Motif ES_0h ES_0h-KLF7_MA1959.2 8 bp overlap

KLF9 3 datasets

Motif ES_0h ES_0h-KLF9_MA1107.3 11 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 161 bp overlap

ChIP HEK293 ENCSR076EZB.KLF9.HEK293 247 bp overlap

Motif ES_0h ES_0h-MAFF_MA0495.4 11 bp overlap

ChIP H1 ENCFF914VQY 264 bp overlap

ChIP dopaminergic-neuron_Dopamine_neurons GSE93905.MED1.dopaminergic-neuron_Dopamine_neurons 139 bp overlap

MXI1 5 datasets

ChIP H1 ENCFF963FZS 337 bp overlap

ChIP WA01 ENCSR000EBR.MXI1.WA01 235 bp overlap

ChIP neural ENCSR934NHU.MXI1.neural 538 bp overlap

ChIP neural cell ENCFF623HQN 559 bp overlap

ChIP neural cell ENCFF623HQN 343 bp overlap

MYOD1 1 dataset

ChIP IMR-90_GM GSE128527.MYOD1.IMR-90_GM 281 bp overlap

Motif ES_0h ES_0h-Mafb_MA0117.3 11 bp overlap

NKX3-1 1 dataset

ChIP islet ERP004003.NKX3-1.islet 213 bp overlap

Motif ES_0h ES_0h-NRL_MA0842.3 12 bp overlap

OGG1 3 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 349 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 320 bp overlap

ChIP HEK293_60_min GSE89017.OGG1.HEK293_60_min 308 bp overlap

OLIG2 2 datasets

ChIP brain-prefrontal-cortex_2017014 GSE129039.OLIG2.brain-prefrontal-cortex_2017014 402 bp overlap

ChIP brain-prefrontal-cortex_2018006 GSE129039.OLIG2.brain-prefrontal-cortex_2018006 351 bp overlap

OVOL1 1 dataset

Motif ES_0h ES_0h-OVOL1_MA1544.2 10 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 157 bp overlap

POLR2A 1 dataset

ChIP neural cell ENCFF604SPB 233 bp overlap

POU5F1 2 datasets

ChIP BG03 GSE21614.POU5F1.BG03 204 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 231 bp overlap

Prdm15 1 dataset

Motif ES_0h ES_0h-Prdm15_MA1616.2 11 bp overlap

RBBP5 2 datasets

ChIP H1 ENCFF905HFL 200 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 578 bp overlap

REST 2 datasets

ChIP CD4 GSE49570.REST.CD4 159 bp overlap

ChIP neural ENCSR000BTV.REST.neural 329 bp overlap

RFX1 8 datasets

Motif ES_0h ES_0h-RFX1_MA0509.3 16 bp overlap

ChIP K-562 ENCSR968GIB.RFX1.K-562 445 bp overlap

ChIP K-562 ENCSR041AXL.RFX1.K-562 432 bp overlap

ChIP K562 ENCFF421AVO 393 bp overlap

ChIP K562 ENCFF809XVG 235 bp overlap

ChIP MCF-7 ENCFF782EZS 441 bp overlap

ChIP MCF-7 ENCFF782EZS 270 bp overlap

ChIP MCF-7 ENCSR066TET.RFX1.MCF-7 377 bp overlap

Motif ES_0h ES_0h-RFX2_MA0600.3 14 bp overlap

RFX3 2 datasets

Motif ES_0h ES_0h-RFX3_MA0798.3 16 bp overlap

Motif ES_0h ES_0h-RFX3_MA0798.3 16 bp overlap

Motif ES_0h ES_0h-RFX4_MA0799.3 13 bp overlap

RFX5 2 datasets

Motif ES_0h ES_0h-RFX5_MA0510.3 14 bp overlap

Motif ES_0h ES_0h-RFX5_MA0510.3 14 bp overlap

RUNX2 1 dataset

Motif ES_0h ES_0h-RUNX2_MA0511.2 9 bp overlap

ChIP TSU-1621MT GSE60477.RXR.TSU-1621MT 213 bp overlap

SIN3A 4 datasets

ChIP H1 ENCFF042ZSL 479 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 556 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 232 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 305 bp overlap

SMAD2 2 datasets

Motif ES_0h ES_0h-SMAD2_MA1964.2 6 bp overlap

Motif ES_0h ES_0h-SMAD2_MA1964.2 6 bp overlap

SMARCA4 2 datasets

ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 297 bp overlap

ChIP NSC GSE125033.SMARCA4.NSC 240 bp overlap

SNAI1 1 dataset

Motif ES_0h ES_0h-SNAI1_MA1558.2 7 bp overlap

ChIP HEK293 GSE76494.SP1.HEK293 125 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 190 bp overlap

Motif ES_0h ES_0h-SP3_MA0746.3 11 bp overlap

Motif ES_0h ES_0h-SP4_MA0685.2 9 bp overlap

ChIP HEK293 GSE76494.SP4.HEK293 114 bp overlap

Motif ES_0h ES_0h-SP8_MA0747.2 11 bp overlap

Motif ES_0h ES_0h-SP9_MA1564.2 10 bp overlap

Motif ES_0h ES_0h-SPIC_MA0687.2 13 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 196 bp overlap

ChIP neural cell ENCFF468SPD 562 bp overlap

TBL1X 1 dataset

ChIP HEK293T GSE35197.TBL1X.HEK293T 212 bp overlap

TCF12 1 dataset

Motif ES_0h ES_0h-TCF12_MA1648.2 7 bp overlap

TCF3 2 datasets

Motif ES_0h ES_0h-TCF3_MA0522.4 7 bp overlap

ChIP NPC GSE154479.TCF3.NPC 372 bp overlap

TEAD1 1 dataset

ChIP H69 GSE62274.TEAD1.H69 151 bp overlap

TEAD4 2 datasets

ChIP ESC S26-ESC-d0-TEAD4-exp1 259 bp overlap

ChIP H1 ENCFF778PAX 245 bp overlap

TFAP4 1 dataset

ChIP K562 ENCFF727PXG 86 bp overlap

ChIP WA01 ENCSR000BIU.USF1.WA01 134 bp overlap

ZBTB24 3 datasets

Motif ES_0h ES_0h-ZBTB24_MA2330.1 10 bp overlap

Motif ES_0h ES_0h-ZBTB24_MA2330.1 10 bp overlap

Motif ES_0h ES_0h-ZBTB24_MA2330.1 10 bp overlap

Motif ES_0h ES_0h-ZEB1_MA0103.4 6 bp overlap

ZFP14 1 dataset

Motif ES_0h ES_0h-ZFP14_MA1972.1 15 bp overlap

ZFP42 1 dataset

Motif ES_0h ES_0h-ZFP42_MA1651.2 13 bp overlap

ZNF136 1 dataset

Motif ES_0h ES_0h-ZNF136_MA1588.1 15 bp overlap

ZNF343 1 dataset

Motif ES_0h ES_0h-ZNF343_MA1711.2 16 bp overlap

ZNF416 2 datasets

Motif ES_0h ES_0h-ZNF416_MA1979.2 10 bp overlap

Motif ES_0h ES_0h-ZNF416_MA1979.2 10 bp overlap

ZNF449 1 dataset

ChIP HEK293 ENCFF764ZIC 179 bp overlap

ZNF454 1 dataset

Motif ES_0h ES_0h-ZNF454_MA1712.2 17 bp overlap

ZNF467 1 dataset

ChIP HEK293 GSE76494.ZNF467.HEK293 56 bp overlap

ZNF534 1 dataset

ChIP HEK293T GSE78099.ZNF534.HEK293T 71 bp overlap

ZNF692 1 dataset

Motif ES_0h ES_0h-ZNF692_MA1986.2 8 bp overlap

ZNF708 1 dataset

Motif ES_0h ES_0h-ZNF708_MA1730.2 9 bp overlap

Zfp809 2 datasets

Motif ES_0h ES_0h-Zfp809_MA2125.1 9 bp overlap

Motif ES_0h ES_0h-Zfp809_MA2125.1 9 bp overlap

Zic1::Zic2 2 datasets

Motif ES_0h ES_0h-Zic1Zic2_MA1628.2 7 bp overlap

Motif ES_0h ES_0h-Zic1Zic2_MA1628.2 7 bp overlap

Motif ES_0h ES_0h-Zic2_MA1629.2 9 bp overlap

Zic3 2 datasets

Motif ES_0h ES_0h-Zic3_MA0697.3 7 bp overlap

Motif ES_0h ES_0h-Zic3_MA0697.3 7 bp overlap