chr8:30,087,943–30,088,717

chr8 : 30,087,943 – 30,088,717

774 bp 89 TFs 7 linked genes

This 774 bp open chromatin element is linked to 7 target genes and is bound by 89 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SARAF		4.9 kb	Proximal	Proximity
ENSG00000272256		5.2 kb	Proximal	Proximity
ENSG00000289334		6.7 kb	Proximal	Proximity
LEPROTL1		6.7 kb	Proximal	Proximity
DCTN6		68.1 kb	Distal	Multiome
DCTN6-DT		68.4 kb	Distal	Multiome
RBPMS		296.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

89 transcription factors

ARID4B 1 dataset

ChIP WTC11 ENCFF441HDK 457 bp overlap

ASH2L 3 datasets

ChIP H1 ENCFF399KAM 732 bp overlap

ChIP H1 ENCFF399KAM 626 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 571 bp overlap

BCOR 2 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 527 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 586 bp overlap

BHLHE22 1 dataset

Motif DE_24h DE_24h-BHLHE22_MA1635.2 6 bp overlap

BRD2 4 datasets

ChIP MDA-MB-231_BAZ2AsiRNA GSE116879.BRD2.MDA-MB-231_BAZ2AsiRNA 472 bp overlap

ChIP MDA-MB-231_BAZ2BsiRNA GSE116879.BRD2.MDA-MB-231_BAZ2BsiRNA 438 bp overlap

ChIP MDA-MB-231_NTsiRNA GSE116879.BRD2.MDA-MB-231_NTsiRNA 333 bp overlap

ChIP THP-1_DMSO GSE138084.BRD2.THP-1_DMSO 357 bp overlap

ChIP CLL_patient2 GSE109411.BRD4.CLL_patient2 242 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 342 bp overlap

CDKN1B 2 datasets

ChIP MDA-MB-231 GSE112444.CDKN1B.MDA-MB-231 240 bp overlap

ChIP MDA-MB-231_p27CK-DD GSE112444.CDKN1B.MDA-MB-231_p27CK-DD 410 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 417 bp overlap

ChIP BLaER1 ENCFF335XTP 280 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 323 bp overlap

E2F5 2 datasets

ChIP WTC11 ENCFF449LLF 491 bp overlap

ChIP WTC11 ENCFF449LLF 491 bp overlap

E2F6 3 datasets

ChIP H1 ENCFF785DWK 296 bp overlap

ChIP H1 ENCFF785DWK 119 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 513 bp overlap

ChIP ME-1 GSE46044.ELF1.ME-1 268 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 352 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 222 bp overlap

EZH2_phosphoT487 2 datasets

ChIP PC-9 ENCSR702GMW.EZH2_phosphoT487.PC-9 68 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 565 bp overlap

FEZF2 1 dataset

Motif DE_24h DE_24h-FEZF2_MA2341.1 8 bp overlap

FOXP1 1 dataset

ChIP WTC11 ENCFF338WGC 525 bp overlap

FOXP4 2 datasets

ChIP WTC11 ENCFF708TAF 328 bp overlap

ChIP WTC11 ENCFF708TAF 377 bp overlap

GATA4 1 dataset

ChIP DE DE-GATA4-2 333 bp overlap

GTF2F1 1 dataset

ChIP H1 ENCFF399TGL 345 bp overlap

HINFP 2 datasets

Motif DE_12h DE_12h-HINFP_MA0131.3 8 bp overlap

Motif DE_24h DE_24h-HINFP_MA0131.3 8 bp overlap

HMGXB4 1 dataset

ChIP WTC11 ENCFF962POR 613 bp overlap

ChIP WTC11 ENCFF506LYD 304 bp overlap

JARID2 1 dataset

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 314 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 390 bp overlap

ChIP MDA-BoM-1833_shp27 GSE112444.JUN.MDA-BoM-1833_shp27 221 bp overlap

ChIP MDA-MB-231 GSE112444.JUN.MDA-MB-231 230 bp overlap

KDM4A 4 datasets

ChIP H1 ENCFF078LED 492 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 508 bp overlap

ChIP hiPSC_IA12 GSE106870.KDM4A.hiPSC_IA12 290 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 175 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 302 bp overlap

ChIP A549 ENCFF371EPR 94 bp overlap

ChIP H1 ENCFF914VQY 146 bp overlap

ChIP WTC11 ENCFF223QFY 368 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 388 bp overlap

MYOCD 1 dataset

ChIP A-549 GSE128921.MYOCD.A-549 460 bp overlap

Motif DE_24h DE_24h-MYOG_MA0500.3 8 bp overlap

NANOG 3 datasets

ChIP HUES-8 GSE109524.NANOG.HUES-8 124 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 360 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 398 bp overlap

NFATC3 1 dataset

ChIP K562 ENCFF078EKB 242 bp overlap

NFE2L1 2 datasets

ChIP WTC11 ENCFF644BPU 377 bp overlap

ChIP WTC11 ENCFF644BPU 320 bp overlap

NFKBIA 1 dataset

ChIP dermal GSE30082.NFKBIA.dermal 296 bp overlap

NFYA 3 datasets

ChIP K-562 GSE26439.NFYA.K-562 100 bp overlap

ChIP K562 ENCFF666BET 198 bp overlap

ChIP K562 ENCFF732HOX 210 bp overlap

NFYB 9 datasets

ChIP GM12878 ENCFF474DNH 226 bp overlap

ChIP GM12878 ENCSR000DNM.NFYB.GM12878 223 bp overlap

ChIP HeLa-S3 ENCFF854TNJ 228 bp overlap

ChIP HeLa-S3 ENCSR000DNR.NFYB.HeLa-S3 63 bp overlap

ChIP HepG2 ENCFF174VYX 98 bp overlap

ChIP K-562 ENCSR000EGQ.NFYB.K-562 224 bp overlap

ChIP K-562 GSE26439.NFYB.K-562 110 bp overlap

ChIP K562 ENCFF709RXX 68 bp overlap

ChIP WTC11 ENCFF751ZTQ 164 bp overlap

ChIP HepG2 ENCFF836FYP 94 bp overlap

NHLH1 1 dataset

Motif DE_24h DE_24h-NHLH1_MA0048.3 9 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 462 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 425 bp overlap

ChIP HMEC-1 GSE67867.NRF1.HMEC-1 144 bp overlap

Neurod2 1 dataset

Motif DE_24h DE_24h-Neurod2_MA1993.2 6 bp overlap

ChIP HEK293 GSE89017.OGG1.HEK293 276 bp overlap

Olig2 1 dataset

Motif DE_24h DE_24h-Olig2_MA1997.2 6 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 566 bp overlap

PHF8 2 datasets

ChIP H1 ENCFF427UFV 227 bp overlap

ChIP WA01 ENCSR000ATK.PHF8.WA01 365 bp overlap

POLR2A 3 datasets

ChIP GM23338 ENCFF450WCS 491 bp overlap

ChIP H1 ENCFF566JSR 204 bp overlap

ChIP H1 ENCFF566JSR 220 bp overlap

POU5F1 4 datasets

ChIP BG03 GSE21614.POU5F1.BG03 201 bp overlap

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 106 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 561 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 391 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 499 bp overlap

RBBP5 2 datasets

ChIP H1 ENCFF905HFL 320 bp overlap

ChIP WA01 ENCSR000AQC.RBBP5.WA01 381 bp overlap

ChIP WA09 GSE105028.RNF2.WA09 188 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 411 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 431 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 586 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 159 bp overlap

ChIP WTC11 ENCFF891HYW 224 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 313 bp overlap

SMARCC1 1 dataset

ChIP ESC S25-ESC-d0-BAF155-exp1 287 bp overlap

ChIP RENVM GSE49404.SOX2.RENVM 159 bp overlap

ChIP H1 ENCFF263FUH 195 bp overlap

ChIP K562 ENCFF365HQT 117 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 130 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 397 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 299 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 264 bp overlap

SUZ12 1 dataset

ChIP hiPSC_WT GSE124903.SUZ12.hiPSC_WT 88 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 159 bp overlap

ChIP WA01 ENCSR000BHO.TAF1.WA01 659 bp overlap

ChIP H1 ENCFF859IIO 315 bp overlap

ChIP WA01 ENCSR000ECB.TBP.WA01 241 bp overlap

ChIP hESC_2h GSE122298.TBP.hESC_2h 128 bp overlap

ChIP hiPSC_WTb_RNase-pos GSE128135.TBP.hiPSC_WTb_RNase-pos 280 bp overlap

Motif DE_12h DE_12h-THRB_MA1575.2 17 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 393 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 572 bp overlap

Tcf12 1 dataset

Motif DE_24h DE_24h-Tcf12_MA0521.3 6 bp overlap

Tfcp2l1 1 dataset

Motif DE_12h DE_12h-Tfcp2l1_MA0145.2 14 bp overlap

Twist2 1 dataset

Motif DE_24h DE_24h-Twist2_MA0633.3 6 bp overlap

ChIP WTC11 ENCFF139JAW 417 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 492 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 245 bp overlap

ZBTB33 4 datasets

ChIP GM12878 ENCFF818EFA 77 bp overlap

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 774 bp overlap

ChIP K562 ENCFF427SDV 505 bp overlap

ChIP K562 ENCFF875HLX 99 bp overlap

ZBTB6 2 datasets

Motif DE_12h DE_12h-ZBTB6_MA1581.2 9 bp overlap

Motif DE_24h DE_24h-ZBTB6_MA1581.2 9 bp overlap

Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap

Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap

ZMYM4 1 dataset

ChIP HepG2 ENCFF567SQY 211 bp overlap

ZNF143 1 dataset

ChIP WTC11 ENCFF249JUK 485 bp overlap

ZNF213 1 dataset

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

ZNF281 1 dataset

ChIP K-562 GSE121133.ZNF281.K-562 198 bp overlap

ZNF316 1 dataset

ChIP K562 ENCFF838QCD 263 bp overlap

ZNF449 1 dataset

Motif DE_24h DE_24h-ZNF449_MA1656.2 10 bp overlap

ZNF574 2 datasets

Motif DE_12h DE_12h-ZNF574_MA1982.2 14 bp overlap

Motif DE_24h DE_24h-ZNF574_MA1982.2 14 bp overlap

ZNF768 1 dataset

Motif DE_12h DE_12h-ZNF768_MA1731.2 9 bp overlap

Zic1::Zic2 1 dataset

Motif DE_24h DE_24h-Zic1Zic2_MA1628.2 7 bp overlap

Motif DE_24h DE_24h-Zic2_MA1629.2 9 bp overlap

Motif DE_24h DE_24h-Zic3_MA0697.3 7 bp overlap