chr3:183,883,494–183,884,017

chr3 : 183,883,494 – 183,884,017

523 bp 83 TFs 10 linked genes

This 523 bp open chromatin element is linked to 10 target genes and is bound by 83 transcription factors.

Linked Genes

10 genes

Gene	Expression	Dist. to TSS	Distance	Link type
PARL		862 bp	At TSS	Proximity
ENSG00000283765		871 bp	At TSS	Proximity
ENSG00000293259		905 bp	At TSS	Proximity
ABCC5		134.3 kb	Distal	Multiome
YEATS2		185.8 kb	Distal	Multiome
KLHL24		248.0 kb	Distal	Multiome
EIF2B5		251.8 kb	Distal	Multiome
DVL3		271.8 kb	Distal	Multiome
AP2M1		291.3 kb	Distal	Multiome
ALG3		365.9 kb	Distal	Multiome+HiCAR

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

83 transcription factors

ChIP LNCaP_R1881 GSE69043.AR.LNCaP_R1881 164 bp overlap

ChIP LNCaP_SHGATA2_R1881 GSE69043.AR.LNCaP_SHGATA2_R1881 126 bp overlap

ChIP prostate_1592_T GSE130408.AR.prostate_1592_T 247 bp overlap

ARID2 1 dataset

ChIP Hep-G2 GSE69566.ARID2.Hep-G2 232 bp overlap

ASCL1 1 dataset

ChIP NCI-H82 GSE69394.ASCL1.NCI-H82 267 bp overlap

ASH2L 1 dataset

ChIP Hep-G2 ENCSR508LMH.ASH2L.Hep-G2 328 bp overlap

ChIP K-562 ENCSR145TSJ.ATF4.K-562 154 bp overlap

BRD2 2 datasets

ChIP THP-1_DMSO GSE138084.BRD2.THP-1_DMSO 294 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD2.THP-1_iBET-BD2 365 bp overlap

BRD3 3 datasets

ChIP MV4-11_DMSO GSE120715.BRD3.MV4-11_DMSO 403 bp overlap

ChIP MV4-11_IBET151_500nM GSE120715.BRD3.MV4-11_IBET151_500nM 291 bp overlap

ChIP MV4-11_IBET151_50nM GSE120715.BRD3.MV4-11_IBET151_50nM 416 bp overlap

BRD4 9 datasets

ChIP CLL_patient4_4h_CpG GSE109411.BRD4.CLL_patient4_4h_CpG 120 bp overlap

ChIP HCT-15 GSE73319.BRD4.HCT-15 89 bp overlap

ChIP LNCaP-C4-2_F133V_JQ1 GSE88871.BRD4.LNCaP-C4-2_F133V_JQ1 75 bp overlap

ChIP LNCaP-C4-2_OE GSE88871.BRD4.LNCaP-C4-2_OE 228 bp overlap

ChIP MOLM-14_DMSO GSE65138.BRD4.MOLM-14_DMSO 185 bp overlap

ChIP MV4-11_DMSO GSE120715.BRD4.MV4-11_DMSO 275 bp overlap

ChIP MV4-11_IBET151_500nM GSE120715.BRD4.MV4-11_IBET151_500nM 56 bp overlap

ChIP MV4-11_IBET151_50nM GSE120715.BRD4.MV4-11_IBET151_50nM 135 bp overlap

ChIP THP-1_iBET-BD2 GSE138084.BRD4.THP-1_iBET-BD2 436 bp overlap

CEBPA 4 datasets

ChIP Hep-G2 ERP000209.CEBPA.Hep-G2 111 bp overlap

ChIP MV4-11 GSE88746.CEBPA.MV4-11 95 bp overlap

ChIP T-47D GSE132649.CEBPA.T-47D 325 bp overlap

ChIP T-47D_progesterone GSE132649.CEBPA.T-47D_progesterone 230 bp overlap

CEBPB 6 datasets

ChIP HeLa-S3 ENCFF722WEG 265 bp overlap

ChIP Hep-G2 ENCSR000EEX.CEBPB.Hep-G2 131 bp overlap

ChIP K-562 ENCSR000EHE.CEBPB.K-562 204 bp overlap

ChIP K-562 ENCSR000BRQ.CEBPB.K-562 249 bp overlap

ChIP MCF-7 ENCSR000BSR.CEBPB.MCF-7 147 bp overlap

ChIP monocyte GSE98367.CEBPB.monocyte 182 bp overlap

CEBPG 1 dataset

ChIP K-562 ENCSR490LWA.CEBPG.K-562 270 bp overlap

CREB1 1 dataset

ChIP LNCaP-abl_SHFOXA1 GSE63034.CREB1.LNCaP-abl_SHFOXA1 199 bp overlap

E2F6 3 datasets

ChIP K-562 ENCSR000EWJ.E2F6.K-562 283 bp overlap

ChIP K-562 ENCSR000BLI.E2F6.K-562 263 bp overlap

ChIP K562 ENCFF163WMT 287 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 457 bp overlap

EP300 1 dataset

ChIP PC-3 GSE147455.EP300.PC-3 178 bp overlap

ChIP RWPE-1 GSE114241.ERG.RWPE-1 142 bp overlap

ChIP T-47D_D538G_E2 GSE148277.ESR1.T-47D_D538G_E2 236 bp overlap

ChIP Jurkat_KO GSE147198.EZH2.Jurkat_KO 61 bp overlap

FOXA1 5 datasets

ChIP LNCaP_DHT24H GSE58428.FOXA1.LNCaP_DHT24H 242 bp overlap

ChIP T-47D_JC4747 GSE126004.FOXA1.T-47D_JC4747 187 bp overlap

ChIP T-47D_JC4748 GSE126004.FOXA1.T-47D_JC4748 239 bp overlap

ChIP VCaP_ETOH24H GSE58428.FOXA1.VCaP_ETOH24H 290 bp overlap

ChIP breast-cancer_3487 GSE126004.FOXA1.breast-cancer_3487 179 bp overlap

FOXA2 4 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 225 bp overlap

ChIP CFPAC-1 GSE119930.FOXA2.CFPAC-1 164 bp overlap

ChIP DE DE-FOXA2-1 523 bp overlap

ChIP DE DE-FOXA2-2 447 bp overlap

FOXL2 1 dataset

ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 206 bp overlap

GATA1 4 datasets

ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 117 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 376 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 153 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 188 bp overlap

GATA2 10 datasets

ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 183 bp overlap

ChIP ESF GSE108408.GATA2.ESF 162 bp overlap

ChIP K-562 ENCSR000DKA.GATA2.K-562 403 bp overlap

ChIP LNCaP GSE38391.GATA2.LNCaP 190 bp overlap

ChIP LNCaP GSE52725.GATA2.LNCaP 190 bp overlap

ChIP LNCaP_CSFCS GSE69043.GATA2.LNCaP_CSFCS 192 bp overlap

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 249 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 182 bp overlap

ChIP dermal-fibroblast_alone GSE51025.GATA2.dermal-fibroblast_alone 228 bp overlap

ChIP primary-endometrial-stromal-cell_IVD_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_IVD_P2 91 bp overlap

GATA3 6 datasets

ChIP A1A3_Brg1KD_Dex GSE112491.GATA3.A1A3_Brg1KD_Dex 270 bp overlap

ChIP MCF-7_sgScr GSE133072.GATA3.MCF-7_sgScr 231 bp overlap

ChIP T-47D GSE51274.GATA3.T-47D 368 bp overlap

ChIP T-47D ENCSR000BMX.GATA3.T-47D 207 bp overlap

ChIP T-47D_sc GSE122847.GATA3.T-47D_sc 237 bp overlap

ChIP breast_tumor_Male_21 GSE104399.GATA3.breast_tumor_Male_21 274 bp overlap

GATA3_Nter 2 datasets

ChIP T-47D_CR3flp GSE99479.GATA3_Nter.T-47D_CR3flp 273 bp overlap

ChIP T-47D_flp-ctrl GSE99479.GATA3_Nter.T-47D_flp-ctrl 225 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 523 bp overlap

ChIP DE DE-GATA4-2 523 bp overlap

ChIP foregut GSE117136.GATA4.foregut 523 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 306 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 334 bp overlap

GATA6 11 datasets

ChIP DE DE-GATA6-1 523 bp overlap

ChIP DE DE-GATA6-2 523 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 523 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 523 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 523 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 523 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 523 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 523 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 522 bp overlap

ChIP foregut GSE117136.GATA6.foregut 336 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 159 bp overlap

GTF2E2 2 datasets

ChIP K562 ENCFF741URT 233 bp overlap

ChIP K562 ENCFF741URT 442 bp overlap

HDAC1 2 datasets

ChIP NB4 GSE126720.HDAC1.NB4 148 bp overlap

ChIP NB4 GSE126720.HDAC1.NB4 126 bp overlap

HDAC2 2 datasets

ChIP K-562 ENCSR893WSB.HDAC2.K-562 242 bp overlap

ChIP PC-3_GDC-resist GSE147455.HDAC2.PC-3_GDC-resist 173 bp overlap

HMBOX1 1 dataset

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 146 bp overlap

HNF4A 1 dataset

ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 104 bp overlap

IKZF1 2 datasets

ChIP K-562 ENCSR395HWC.IKZF1.K-562 453 bp overlap

ChIP K562 ENCFF771OHZ 387 bp overlap

ChIP K-562 GSE103215.ILF3.K-562 145 bp overlap

KMT2A 10 datasets

ChIP HEK293T_C-term_C49 GSE90762.KMT2A.HEK293T_C-term_C49 60 bp overlap

ChIP HEK293T_N-term GSE90762.KMT2A.HEK293T_N-term 428 bp overlap

ChIP HEK293T_N-term_C49 GSE90762.KMT2A.HEK293T_N-term_C49 373 bp overlap

ChIP HEK293T_N-term_C49 GSE90762.KMT2A.HEK293T_N-term_C49 99 bp overlap

ChIP HEK293T_N-term_shCtrl GSE90762.KMT2A.HEK293T_N-term_shCtrl 96 bp overlap

ChIP Hep-G2 ENCSR692GFR.KMT2A.Hep-G2 247 bp overlap

ChIP MOLM-13_CBS79-KO-VP-HOTTIP GSE114981.KMT2A.MOLM-13_CBS79-KO-VP-HOTTIP 113 bp overlap

ChIP MOLM-13_HOTTIP-KO GSE114981.KMT2A.MOLM-13_HOTTIP-KO 187 bp overlap

ChIP MV4-11 GSE83671.KMT2A.MV4-11 488 bp overlap

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 155 bp overlap

L3MBTL2 2 datasets

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 305 bp overlap

ChIP K562 ENCFF320EQC 276 bp overlap

ChIP HeLa-S3 ENCFF304XGR 210 bp overlap

ChIP HeLa-S3 ENCFF398RFF 267 bp overlap

ChIP HeLa-S3 ENCSR000EZF.MAX.HeLa-S3 132 bp overlap

ChIP HeLa-S3 ENCSR000ECN.MAX.HeLa-S3 134 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 188 bp overlap

ChIP K-562 ENCSR000FAE.MAX.K-562 142 bp overlap

ChIP K562 ENCFF524IJO 117 bp overlap

ChIP MDA-MB-468 GSE81381.MAX.MDA-MB-468 122 bp overlap

ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 82 bp overlap

MEN1 2 datasets

ChIP PC-3 GSE132827.MEN1.PC-3 482 bp overlap

ChIP RS4-11_DMSO-D3-180110 GSE127507.MEN1.RS4-11_DMSO-D3-180110 178 bp overlap

ChIP K-562 ENCSR710WLO.MGA.K-562 256 bp overlap

ChIP K562 ENCFF140CEX 382 bp overlap

MLLT1 1 dataset

ChIP MV4-11 GSE82116.MLLT1.MV4-11 433 bp overlap

ChIP K-562 ENCSR390VGH.MNT.K-562 281 bp overlap

ChIP K-562 ENCSR512NLO.MNT.K-562 174 bp overlap

ChIP K562 ENCFF820IGH 432 bp overlap

MXI1 2 datasets

ChIP IMR-90 ENCSR000EFE.MXI1.IMR-90 166 bp overlap

ChIP SK-N-SH ENCSR000EIA.MXI1.SK-N-SH 184 bp overlap

ChIP K-562 ENCSR000EZU.MYC.K-562 144 bp overlap

ChIP SK-N-AS GSE138295.MYC.SK-N-AS 113 bp overlap

MYCN 4 datasets

ChIP BE2C GSE80151.MYCN.BE2C 271 bp overlap

ChIP CHP-134 GSE129588.MYCN.CHP-134 149 bp overlap

ChIP LNCaP_DHT GSE117304.MYCN.LNCaP_DHT 268 bp overlap

ChIP SK-N-BE2-C GSE80151.MYCN.SK-N-BE2-C 227 bp overlap

ChIP K-562 ENCSR085QEV.NBN.K-562 312 bp overlap

NEUROD1 2 datasets

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 254 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 162 bp overlap

NFATC2 3 datasets

ChIP CD4_CD28-ab GSE116695.NFATC2.CD4_CD28-ab 88 bp overlap

ChIP CD4_fly-DNA GSE116695.NFATC2.CD4_fly-DNA 65 bp overlap

ChIP CD4_fly-DNA_no-CD28 GSE116695.NFATC2.CD4_fly-DNA_no-CD28 145 bp overlap

NIPBL 1 dataset

ChIP HCT-116_RAD21-mAC_500uM_auxin GSE104888.NIPBL.HCT-116_RAD21-mAC_500uM_auxin 183 bp overlap

NR2C1 1 dataset

ChIP K-562 ENCSR742IDN.NR2C1.K-562 76 bp overlap

NR2C2 1 dataset

ChIP Hep-G2 ENCSR559ZKI.NR2C2.Hep-G2 153 bp overlap

ONECUT1 1 dataset

ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 288 bp overlap

ChIP Hep-G2 ENCSR604VAE.PHF8.Hep-G2 156 bp overlap

PHIP 2 datasets

ChIP HCT-116_MLL1-KO__ab833 GSE101646.PHIP.HCT-116_MLL1-KO__ab833 428 bp overlap

ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 340 bp overlap

RBFOX2 1 dataset

ChIP K-562 GSE120104.RBFOX2.K-562 216 bp overlap

RCOR1 1 dataset

ChIP keratinocyte_diff GSE57702.RCOR1.keratinocyte_diff 148 bp overlap

RUNX1 1 dataset

ChIP VCaP_DHT24H GSE58428.RUNX1.VCaP_DHT24H 454 bp overlap

SAP130 1 dataset

ChIP HepG2 ENCFF892EHZ 83 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 514 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 459 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 322 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 292 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 305 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 493 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 316 bp overlap

SMARCA4 6 datasets

ChIP A-549_AG15684 GSE132290.SMARCA4.A-549_AG15684 268 bp overlap

ChIP A-549_AG15685 GSE132290.SMARCA4.A-549_AG15685 239 bp overlap

ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-K785R 459 bp overlap

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-T910M 313 bp overlap

ChIP K-562 ENCSR643VTW.SMARCA4.K-562 221 bp overlap

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 169 bp overlap

SMARCC1 1 dataset

ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SMARCC1.BIN-67_lentivirus-SMARCA4-K785R 216 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 162 bp overlap

SNAI2 1 dataset

ChIP PC-9_2DF GSE131687.SNAI2.PC-9_2DF 66 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 404 bp overlap

ChIP K-562 ENCSR788RSW.SOX6.K-562 248 bp overlap

SPDEF 1 dataset

ChIP MCF-7 ENCSR042GSX.SPDEF.MCF-7 194 bp overlap

TBX21 1 dataset

ChIP GM12878 ENCSR739IHN.TBX21.GM12878 97 bp overlap

TEAD4 1 dataset

ChIP T-47D_E2 GSE125594.TEAD4.T-47D_E2 90 bp overlap

TFDP1 1 dataset

ChIP K562 ENCFF794ZXJ 481 bp overlap

ChIP K562 ENCFF633EZB 259 bp overlap

ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 435 bp overlap

ZBTB17 1 dataset

ChIP HEK293 ENCFF865LIO 435 bp overlap

ZBTB33 1 dataset

ChIP GM12878 ENCFF818EFA 81 bp overlap

ChIP K-562 ENCSR004GKA.ZEB2.K-562 237 bp overlap

ChIP K562 ENCFF536AJO 274 bp overlap

ZGPAT 1 dataset

ChIP Hep-G2 ENCSR704IGU.ZGPAT.Hep-G2 266 bp overlap

ZNF133 2 datasets

ChIP HEK293 ENCFF844RST 385 bp overlap

ChIP HEK293 ENCSR283MWQ.ZNF133.HEK293 353 bp overlap

ZNF24 1 dataset

ChIP K-562 ENCSR099NCH.ZNF24.K-562 478 bp overlap

ZNF280D 1 dataset

ChIP HepG2 ENCFF203BIA 482 bp overlap

ZNF335 1 dataset

ChIP HEK293 ENCFF784SLD 295 bp overlap

ZNF592 2 datasets

ChIP K-562 ENCSR249BHQ.ZNF592.K-562 220 bp overlap

ChIP K562 ENCFF547OSS 352 bp overlap