chr19:51,311,132–51,312,279

chr19 : 51,311,132 – 51,312,279

1,147 bp 99 TFs 6 linked genes

This 1.1 kb open chromatin element is linked to 6 target genes and is bound by 99 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
IGLON5		at TSS	At TSS	Proximity
VSIG10L		28.2 kb	Distal	Multiome
ETFB		54.8 kb	Distal	Multiome
LIM2-AS1		82.9 kb	Distal	Multiome
CTU1		203.2 kb	Distal	Multiome
KLK10		291.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

99 transcription factors

ARID1B 1 dataset

ChIP MCF-7_shJUN GSE128445.ARID1B.MCF-7_shJUN 251 bp overlap

BCOR 4 datasets

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 288 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 311 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 264 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 467 bp overlap

BRD4 16 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 362 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 621 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 362 bp overlap

ChIP cortical-interneuron_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_KCl-pos_JQ1-neg 215 bp overlap

ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 274 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 276 bp overlap

ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 149 bp overlap

ChIP hESC GSE33281.BRD4.hESC 80 bp overlap

ChIP hESC GSE33281.BRD4.hESC 98 bp overlap

ChIP hESC GSE33281.BRD4.hESC 114 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 342 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 379 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 288 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 356 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 224 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 399 bp overlap

CHD2 2 datasets

ChIP SK-N-SH ENCSR274SLQ.CHD2.SK-N-SH 123 bp overlap

ChIP WA01 ENCSR000EBT.CHD2.WA01 142 bp overlap

ChIP anterior-temporal-cortex_fetal GSE116825.CTCF.anterior-temporal-cortex_fetal 200 bp overlap

ChIP A-375 GSE116190.EGR1.A-375 72 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 353 bp overlap

ChIP K-562 GSE23730.ERG.K-562 191 bp overlap

ChIP K-562_DOX GSE23730.ERG.K-562_DOX 311 bp overlap

ETS1 6 datasets

ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 477 bp overlap

ChIP cardiomyocyte_D0 GSE129986.ETS1.cardiomyocyte_D0 134 bp overlap

ChIP cardiomyocyte_D2 GSE129986.ETS1.cardiomyocyte_D2 434 bp overlap

ChIP cardiomyocyte_D5 GSE129986.ETS1.cardiomyocyte_D5 467 bp overlap

ChIP cardiomyocyte_D5 GSE129986.ETS1.cardiomyocyte_D5 213 bp overlap

ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 415 bp overlap

EZH2 5 datasets

ChIP A-1847 GSE95643.EZH2.A-1847 249 bp overlap

ChIP Hep-3B2-1-7 GSE128137.EZH2.Hep-3B2-1-7 358 bp overlap

ChIP LNCaP-abl GSE39459.EZH2.LNCaP-abl 158 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 90 bp overlap

ChIP hepatocyte ENCFF552DZB 493 bp overlap

EZH2_phosphoT487 1 dataset

ChIP neuron_bipolar_doxy_4d ENCSR886KKK.EZH2_phosphoT487.neuron_bipolar_doxy_4d 334 bp overlap

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 251 bp overlap

FOXA2 1 dataset

ChIP BJ1-hTERT_FoxHnf1aCoExp GSE90454.FOXA2.BJ1-hTERT_FoxHnf1aCoExp 175 bp overlap

GLI3 2 datasets

Motif DE_60h DE_60h-GLI3_MA1491.3 15 bp overlap

Motif DE_72h DE_72h-GLI3_MA1491.3 15 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 915 bp overlap

HDAC2 1 dataset

ChIP WA01 ENCSR000AVB.HDAC2.WA01 137 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 182 bp overlap

HNRNPK 2 datasets

ChIP K-562 GSE120104.HNRNPK.K-562 172 bp overlap

ChIP K-562 ENCSR014RCS.HNRNPK.K-562 171 bp overlap

Hand1 1 dataset

Motif DE_72h DE_72h-Hand1_MA2123.1 9 bp overlap

JARID2 1 dataset

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 203 bp overlap

KDM4A 6 datasets

ChIP WA01 ENCSR000AVC.KDM4A.WA01 213 bp overlap

ChIP WA01 ENCSR000AVC.KDM4A.WA01 348 bp overlap

ChIP hiPSC_IA12 GSE106870.KDM4A.hiPSC_IA12 458 bp overlap

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 170 bp overlap

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 370 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 291 bp overlap

KLF10 1 dataset

Motif DE_72h DE_72h-KLF10_MA1511.2 9 bp overlap

KLF12 3 datasets

Motif DE_60h DE_60h-KLF12_MA0742.2 9 bp overlap

Motif DE_72h DE_72h-KLF12_MA0742.2 9 bp overlap

Motif DE_72h DE_72h-KLF12_MA0742.2 9 bp overlap

KLF13 2 datasets

Motif DE_60h DE_60h-KLF13_MA0657.2 17 bp overlap

Motif DE_72h DE_72h-KLF13_MA0657.2 17 bp overlap

KLF14 1 dataset

Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap

KLF16 2 datasets

Motif DE_60h DE_60h-KLF16_MA0741.1 11 bp overlap

Motif DE_72h DE_72h-KLF16_MA0741.1 11 bp overlap

Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap

ChIP GBM1A GSE62211.KLF9.GBM1A 116 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 338 bp overlap

Motif DE_72h DE_72h-MAZ_MA1522.2 8 bp overlap

MED26 1 dataset

ChIP U2OS_SHEP400 GSE73742.MED26.U2OS_SHEP400 278 bp overlap

ChIP DU145_SH4 GSE135623.MTF2.DU145_SH4 371 bp overlap

ChIP CD34 GSE85488.MYC.CD34 117 bp overlap

MYOCD 1 dataset

ChIP A-549 GSE128921.MYOCD.A-549 357 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 588 bp overlap

NFYA 2 datasets

Motif DE_60h DE_60h-NFYA_MA0060.4 8 bp overlap

Motif DE_72h DE_72h-NFYA_MA0060.4 8 bp overlap

NFYB 4 datasets

Motif DE_60h DE_60h-NFYB_MA0502.3 9 bp overlap

Motif DE_72h DE_72h-NFYB_MA0502.3 9 bp overlap

ChIP K-562 ENCSR000EGQ.NFYB.K-562 251 bp overlap

ChIP K562 ENCFF709RXX 317 bp overlap

NFYC 2 datasets

Motif DE_60h DE_60h-NFYC_MA1644.2 7 bp overlap

Motif DE_72h DE_72h-NFYC_MA1644.2 7 bp overlap

NR2C2 2 datasets

Motif DE_60h DE_60h-NR2C2_MA0504.2 14 bp overlap

Motif DE_72h DE_72h-NR2C2_MA0504.2 14 bp overlap

NR2F1 4 datasets

Motif DE_60h DE_60h-NR2F1_MA0017.3 12 bp overlap

Motif DE_60h DE_60h-NR2F1_MA1537.2 13 bp overlap

Motif DE_72h DE_72h-NR2F1_MA0017.3 12 bp overlap

Motif DE_72h DE_72h-NR2F1_MA1537.2 13 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 558 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 627 bp overlap

OGG1 2 datasets

ChIP HEK293 GSE89017.OGG1.HEK293 234 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 250 bp overlap

PATZ1 5 datasets

Motif DE_60h DE_60h-PATZ1_MA1961.2 11 bp overlap

Motif DE_60h DE_60h-PATZ1_MA1961.2 11 bp overlap

Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap

Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap

Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap

ChIP RCH-ACV GSE85988.PBX1.RCH-ACV 568 bp overlap

PBX3 2 datasets

ChIP GM12878 ENCSR000BGR.PBX3.GM12878 112 bp overlap

ChIP SK-N-SH ENCFF876BMC 317 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 832 bp overlap

PLAG1 2 datasets

Motif DE_60h DE_60h-PLAG1_MA0163.1 14 bp overlap

Motif DE_72h DE_72h-PLAG1_MA0163.1 14 bp overlap

PLAGL2 2 datasets

Motif DE_60h DE_60h-PLAGL2_MA1548.2 8 bp overlap

Motif DE_72h DE_72h-PLAGL2_MA1548.2 8 bp overlap

POLR2A 2 datasets

ChIP GM23338 ENCFF450WCS 491 bp overlap

ChIP neural cell ENCFF604SPB 165 bp overlap

POU5F1 2 datasets

ChIP DE_D1 DED1-OCT4_Batch_II 596 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 421 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 670 bp overlap

PPARD 2 datasets

Motif DE_60h DE_60h-PPARD_MA1550.2 14 bp overlap

Motif DE_72h DE_72h-PPARD_MA1550.2 14 bp overlap

PRDM9 1 dataset

Motif DE_72h DE_72h-PRDM9_MA1723.2 20 bp overlap

RARA 2 datasets

Motif DE_60h DE_60h-RARA_MA0730.1 17 bp overlap

Motif DE_72h DE_72h-RARA_MA0730.1 17 bp overlap

RARA::RXRA 2 datasets

Motif DE_60h DE_60h-RARARXRA_MA0159.1 17 bp overlap

Motif DE_72h DE_72h-RARARXRA_MA0159.1 17 bp overlap

RARA::RXRG 2 datasets

Motif DE_60h DE_60h-RARARXRG_MA1149.2 17 bp overlap

Motif DE_72h DE_72h-RARARXRG_MA1149.2 17 bp overlap

REST 2 datasets

ChIP neural ENCSR000BTV.REST.neural 200 bp overlap

ChIP neural ENCSR000BTV.REST.neural 135 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 776 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 793 bp overlap

RREB1 2 datasets

Motif DE_60h DE_60h-RREB1_MA0073.2 19 bp overlap

Motif DE_72h DE_72h-RREB1_MA0073.2 19 bp overlap

RUNX1 1 dataset

ChIP ME-1 GSE46044.RUNX1.ME-1 217 bp overlap

RXRB 2 datasets

Motif DE_60h DE_60h-RXRB_MA0855.1 14 bp overlap

Motif DE_72h DE_72h-RXRB_MA0855.1 14 bp overlap

RXRG 2 datasets

Motif DE_60h DE_60h-RXRG_MA0856.1 14 bp overlap

Motif DE_72h DE_72h-RXRG_MA0856.1 14 bp overlap

SIN3A 3 datasets

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 263 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 204 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 235 bp overlap

SMARCA4 3 datasets

ChIP 22Rv1_PTEN-KO GSE115615.SMARCA4.22Rv1_PTEN-KO 272 bp overlap

ChIP NGP_ARID1A-mut2 GSE134626.SMARCA4.NGP_ARID1A-mut2 132 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 258 bp overlap

SOX10 2 datasets

Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 597 bp overlap

SOX4 2 datasets

Motif DE_60h DE_60h-SOX4_MA0867.3 8 bp overlap

Motif DE_72h DE_72h-SOX4_MA0867.3 8 bp overlap

Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap

Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap

Motif DE_60h DE_60h-SP2_MA0516.3 9 bp overlap

Motif DE_72h DE_72h-SP2_MA0516.3 9 bp overlap

Motif DE_72h DE_72h-SP2_MA0516.3 9 bp overlap

Motif DE_60h DE_60h-SP3_MA0746.3 11 bp overlap

Motif DE_72h DE_72h-SP3_MA0746.3 11 bp overlap

Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

Motif DE_60h DE_60h-SP8_MA0747.2 11 bp overlap

Motif DE_72h DE_72h-SP8_MA0747.2 11 bp overlap

Motif DE_72h DE_72h-SP9_MA1564.2 10 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 831 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 519 bp overlap

STAT3 1 dataset

ChIP WA01 ERP004237.STAT3.WA01 344 bp overlap

SUZ12 1 dataset

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 68 bp overlap

Sox5 2 datasets

Motif DE_60h DE_60h-Sox5_MA0087.3 8 bp overlap

Motif DE_72h DE_72h-Sox5_MA0087.3 8 bp overlap

TCF12 1 dataset

ChIP ME-1 GSE46044.TCF12.ME-1 121 bp overlap

TFAP2B 2 datasets

ChIP SK-N-SH ENCFF869XXQ 441 bp overlap

ChIP SK-N-SH ENCFF869XXQ 323 bp overlap

TFAP2C 3 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 409 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 381 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 940 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 425 bp overlap

THRB 2 datasets

Motif DE_60h DE_60h-THRB_MA1574.2 13 bp overlap

Motif DE_72h DE_72h-THRB_MA1574.2 13 bp overlap

TRIM24 1 dataset

ChIP LNCaP-abl_ETOH GSE69331.TRIM24.LNCaP-abl_ETOH 504 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 235 bp overlap

VEZF1 6 datasets

Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap

Motif DE_60h DE_60h-VEZF1_MA1578.2 6 bp overlap

Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap

Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap

Motif DE_72h DE_72h-VEZF1_MA1578.2 6 bp overlap

ChIP K562 ENCFF053XDV 671 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 796 bp overlap

ZBTB10 1 dataset

ChIP HEK293 ENCSR004PLU.ZBTB10.HEK293 88 bp overlap

ZBTB24 1 dataset

Motif DE_72h DE_72h-ZBTB24_MA2330.1 10 bp overlap

ZBTB7A 8 datasets

ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 240 bp overlap

ChIP Ishikawa ENCSR000BSZ.ZBTB7A.Ishikawa 240 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 249 bp overlap

ChIP K-562 ENCSR000BME.ZBTB7A.K-562 404 bp overlap

ChIP K-562 GSE103445.ZBTB7A.K-562 291 bp overlap

ChIP VCaP_CSS GSE123089.ZBTB7A.VCaP_CSS 585 bp overlap

ChIP VCaP_DHT GSE123089.ZBTB7A.VCaP_DHT 577 bp overlap

ChIP VCaP_FBS GSE123089.ZBTB7A.VCaP_FBS 268 bp overlap

ZNF148 2 datasets

Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap

Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap

ZNF257 4 datasets

Motif DE_60h DE_60h-ZNF257_MA1710.2 10 bp overlap

Motif DE_60h DE_60h-ZNF257_MA1710.2 10 bp overlap

Motif DE_72h DE_72h-ZNF257_MA1710.2 10 bp overlap

Motif DE_72h DE_72h-ZNF257_MA1710.2 10 bp overlap

ZNF263 1 dataset

ChIP HEK293T GSE78099.ZNF263.HEK293T 181 bp overlap

ZNF281 2 datasets

Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap

Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap

ZNF320 2 datasets

Motif DE_72h DE_72h-ZNF320_MA1976.2 20 bp overlap

Motif DE_72h DE_72h-ZNF320_MA1976.2 20 bp overlap

ZNF454 1 dataset

Motif DE_72h DE_72h-ZNF454_MA1712.2 17 bp overlap

ZNF460 1 dataset

Motif DE_72h DE_72h-ZNF460_MA1596.1 16 bp overlap

ZNF707 2 datasets

Motif DE_60h DE_60h-ZNF707_MA1715.1 15 bp overlap

Motif DE_72h DE_72h-ZNF707_MA1715.1 15 bp overlap

ZNF740 3 datasets

ChIP K-562 ENCSR737UST.ZNF740.K-562 203 bp overlap

ChIP K562 ENCFF505NFV 605 bp overlap

ChIP K562 ENCFF505NFV 605 bp overlap

ZSCAN22 1 dataset

ChIP HEK293 GSE76494.ZSCAN22.HEK293 206 bp overlap