chr1:25,831,516–25,832,168

chr1 : 25,831,516 – 25,832,168

652 bp 89 TFs 9 linked genes

This 652 bp open chromatin element is linked to 9 target genes and is bound by 89 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000272478		at TSS	At TSS	Proximity
MTFR1L		11.9 kb	Distal	Multiome
AUNIP		27.6 kb	Distal	Multiome
SELENON		31.7 kb	Distal	Multiome
PAQR7		43.8 kb	Distal	Multiome
STMN1		74.5 kb	Distal	Multiome
PAFAH2		166.2 kb	Distal	Multiome
MAN1C1		215.1 kb	Distal	Multiome
PDIK1L		279.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

89 transcription factors

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 297 bp overlap

ChIP K562 ENCFF938UXQ 189 bp overlap

ATF1 2 datasets

ChIP K-562 ENCSR000DNZ.ATF1.K-562 132 bp overlap

ChIP K562 ENCFF980NSF 251 bp overlap

BAF155 1 dataset

ChIP VCaP_shARID1A GSE110655.BAF155.VCaP_shARID1A 160 bp overlap

BRD2 2 datasets

ChIP K-562 GSE140325.BRD2.K-562 107 bp overlap

ChIP K-562_dilution-6-100 GSE140325.BRD2.K-562_dilution-6-100 144 bp overlap

ChIP K-562_JQ1_2h GSE99178.BRD4.K-562_JQ1_2h 289 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 255 bp overlap

ChIP K562 ENCFF673OEZ 411 bp overlap

ChIP SET-2 GSE65138.CDK8.SET-2 249 bp overlap

CTBP1 2 datasets

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 358 bp overlap

ChIP K562 ENCFF403WPG 466 bp overlap

CTCF 3 datasets

ChIP K-562 GSE70482.CTCF.K-562 78 bp overlap

ChIP K-562_7140 GSE131349.CTCF.K-562_7140 114 bp overlap

ChIP endodermal cell ENCFF471YCZ 100 bp overlap

ChIP K562 ENCFF775HUO 547 bp overlap

EHMT2 1 dataset

ChIP K562 ENCFF053BWO 385 bp overlap

ChIP K-562 ENCSR000BMD.ELF1.K-562 138 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 346 bp overlap

EP300 3 datasets

ChIP AML GSE131939.EP300.AML 245 bp overlap

ChIP K-562 ENCSR000EGE.EP300.K-562 173 bp overlap

ChIP K562 ENCFF226VMS 317 bp overlap

ChIP ME-1 GSE46044.ERG.ME-1 394 bp overlap

ChIP SKNO-1 GSE23730.ERG.SKNO-1 218 bp overlap

ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 341 bp overlap

ChIP TSU-1621MT_ATRA GSE60477.ERG.TSU-1621MT_ATRA 405 bp overlap

ChIP VCaP_shARID1A GSE110655.ERG.VCaP_shARID1A 540 bp overlap

ESRRA 3 datasets

ChIP K-562 ENCSR486IFJ.ESRRA.K-562 496 bp overlap

ChIP K562 ENCFF968PEP 465 bp overlap

ChIP K562 ENCFF968PEP 396 bp overlap

ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 390 bp overlap

ETV6 4 datasets

ChIP K-562 ENCSR000FCE.ETV6.K-562 439 bp overlap

ChIP K-562 ENCSR124BJR.ETV6.K-562 163 bp overlap

ChIP K562 ENCFF311NMS 200 bp overlap

ChIP K562 ENCFF337WJB 285 bp overlap

EVI1 2 datasets

ChIP SKH1 GSE87283.EVI1.SKH1 347 bp overlap

ChIP SKH1_10d GSE87283.EVI1.SKH1_10d 267 bp overlap

FLI1 3 datasets

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 204 bp overlap

ChIP CTV-1_DSG GSE128835.FLI1.CTV-1_DSG 356 bp overlap

ChIP SKNO-1 GSE23730.FLI1.SKNO-1 319 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 527 bp overlap

ChIP DE DE-FOXA2-2 537 bp overlap

FOXM1 1 dataset

ChIP K-562 ENCSR429QPP.FOXM1.K-562 233 bp overlap

GABPA 1 dataset

ChIP HL-60 ENCFF515BEZ 371 bp overlap

GABPB1 2 datasets

ChIP K-562 ENCSR138YYY.GABPB1.K-562 282 bp overlap

ChIP K562 ENCFF015GDS 165 bp overlap

GATA1 3 datasets

ChIP K-562 GSE107726.GATA1.K-562 349 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 264 bp overlap

ChIP K562 ENCFF094CMK 251 bp overlap

GATA2 5 datasets

ChIP K-562 ENCSR000DKA.GATA2.K-562 520 bp overlap

ChIP SKH1 GSE87283.GATA2.SKH1 597 bp overlap

ChIP SKH1_RUNX1-EVI1_KD GSE87283.GATA2.SKH1_RUNX1-EVI1_KD 318 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 610 bp overlap

ChIP TSU-1621MT GSE60477.GATA2.TSU-1621MT 340 bp overlap

GATA4 5 datasets

ChIP DE DE-GATA4-1 611 bp overlap

ChIP DE DE-GATA4-2 644 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 542 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 294 bp overlap

GATA6 12 datasets

ChIP DE DE-GATA6-1 583 bp overlap

ChIP DE DE-GATA6-2 641 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 615 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 560 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 543 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 648 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 652 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 616 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 552 bp overlap

ChIP foregut GSE117136.GATA6.foregut 555 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 322 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 318 bp overlap

HDAC1 2 datasets

ChIP K-562 ENCSR387UWP.HDAC1.K-562 345 bp overlap

ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 79 bp overlap

HDAC2 3 datasets

ChIP K-562 ENCSR075HTM.HDAC2.K-562 410 bp overlap

ChIP K-562 GSE140325.HDAC2.K-562 240 bp overlap

ChIP K562 ENCFF744ALD 421 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 101 bp overlap

HMBOX1 3 datasets

ChIP K-562 ENCSR757IIU.HMBOX1.K-562 652 bp overlap

ChIP K562 ENCFF055GAZ 239 bp overlap

ChIP K562 ENCFF317JJX 238 bp overlap

ChIP K-562 ENCSR005NMT.ID3.K-562 344 bp overlap

IKZF1 3 datasets

ChIP K-562 ENCSR395HWC.IKZF1.K-562 275 bp overlap

ChIP K562 ENCFF348IBL 430 bp overlap

ChIP K562 ENCFF771OHZ 428 bp overlap

JMJD1C 1 dataset

ChIP Kasumi-1 GSE63484.JMJD1C.Kasumi-1 284 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 476 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 138 bp overlap

LIN54 1 dataset

Motif DE_48h DE_48h-LIN54_MA0619.2 7 bp overlap

ChIP Jurkat GSE94391.LMO1.Jurkat 212 bp overlap

LMO2 2 datasets

ChIP Kasumi-1_SICTR GSE60130.LMO2.Kasumi-1_SICTR 148 bp overlap

ChIP TSU-1621MT GSE60477.LMO2.TSU-1621MT 385 bp overlap

LYL1 2 datasets

ChIP Kasumi-1 GSE63484.LYL1.Kasumi-1 183 bp overlap

ChIP TSU-1621MT GSE60477.LYL1.TSU-1621MT 317 bp overlap

ChIP P493-6_CMYC_1H GSE36354.MAX.P493-6_CMYC_1H 302 bp overlap

MECOM 3 datasets

ChIP SKH1 GSE102697.MECOM.SKH1 277 bp overlap

ChIP SKH1_CEBPA-ER_E2 GSE102697.MECOM.SKH1_CEBPA-ER_E2 348 bp overlap

ChIP SKH1_E2 GSE102697.MECOM.SKH1_E2 348 bp overlap

MEIS1 1 dataset

ChIP CHRF28811 ERR063469.MEIS1.CHRF28811 302 bp overlap

MEIS2 1 dataset

ChIP K-562 ENCSR851BNE.MEIS2.K-562 232 bp overlap

ChIP K-562 ENCSR180NCY.MTA3.K-562 239 bp overlap

ChIP DU528 GSE94000.MYB.DU528 496 bp overlap

ChIP Loucy GSE94000.MYB.Loucy 491 bp overlap

ChIP K562 ENCFF988ZRU 437 bp overlap

ChIP K562 ENCFF988ZRU 356 bp overlap

NCOR1 2 datasets

ChIP K-562 ENCSR798ILC.NCOR1.K-562 351 bp overlap

ChIP K562 ENCFF866HRM 418 bp overlap

ChIP ProEs GSE59087.NFE2.ProEs 96 bp overlap

NR2F1 2 datasets

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 505 bp overlap

ChIP K562 ENCFF221HJH 497 bp overlap

NR2F2 2 datasets

ChIP liver ENCSR338MMB.NR2F2.liver 392 bp overlap

ChIP liver ENCSR168SMX.NR2F2.liver 301 bp overlap

NR4A1 1 dataset

ChIP Kasumi-1 GSE79491.NR4A1.Kasumi-1 199 bp overlap

PKNOX1 1 dataset

ChIP K-562 ENCSR115SMW.PKNOX1.K-562 169 bp overlap

POLR2A 1 dataset

ChIP HL-60 ENCFF321XKE 407 bp overlap

POU4F1 1 dataset

Motif DE_48h DE_48h-POU4F1_MA0790.2 12 bp overlap

POU4F3 1 dataset

Motif DE_48h DE_48h-POU4F3_MA0791.2 12 bp overlap

RBM22 1 dataset

ChIP K-562 GSE120104.RBM22.K-562 149 bp overlap

RBM39 2 datasets

ChIP K-562 GSE120104.RBM39.K-562 139 bp overlap

ChIP K562 ENCFF914PAM 61 bp overlap

RCOR1 1 dataset

ChIP K562 ENCFF216EEJ 297 bp overlap

ChIP K562 ENCFF688UKW 411 bp overlap

RNF2 2 datasets

ChIP ME-1_Con GSE128771.RNF2.ME-1_Con 254 bp overlap

ChIP ME-1_KD GSE128771.RNF2.ME-1_KD 349 bp overlap

RUNX1 11 datasets

ChIP CD34_ADULT GSE70660.RUNX1.CD34_ADULT 74 bp overlap

ChIP Kasumi-1 GSE62847.RUNX1.Kasumi-1 295 bp overlap

ChIP Kasumi-1 GSE65427.RUNX1.Kasumi-1 150 bp overlap

ChIP ME-1 GSE46044.RUNX1.ME-1 318 bp overlap

ChIP ME-1 GSE117138.RUNX1.ME-1 318 bp overlap

ChIP ME-1_CBFB-MYH11-KD GSE117138.RUNX1.ME-1_CBFB-MYH11-KD 325 bp overlap

ChIP ME-1_Con GSE128771.RUNX1.ME-1_Con 325 bp overlap

ChIP ME-1_KD GSE128771.RUNX1.ME-1_KD 318 bp overlap

ChIP SKH1 GSE87283.RUNX1.SKH1 357 bp overlap

ChIP SKH1_RUNX1-EVI1_KD GSE87283.RUNX1.SKH1_RUNX1-EVI1_KD 130 bp overlap

ChIP SKNO-1 GSE23730.RUNX1.SKNO-1 419 bp overlap

RUNX1T1 3 datasets

ChIP CD34 GSE80773.RUNX1T1.CD34 156 bp overlap

ChIP Kasumi-1_shControl-AE GSE115115.RUNX1T1.Kasumi-1_shControl-AE 211 bp overlap

ChIP Kasumi-1_shTAF1-AE GSE115115.RUNX1T1.Kasumi-1_shTAF1-AE 206 bp overlap

RUNX1_mut 2 datasets

ChIP CD34 GSE111917.RUNX1_mut.CD34 88 bp overlap

ChIP CD34 GSE111917.RUNX1_mut.CD34 219 bp overlap

RUNX2 1 dataset

ChIP PER-117 GSE151819.RUNX2.PER-117 236 bp overlap

Rhox11 1 dataset

Motif DE_48h DE_48h-Rhox11_MA0629.2 9 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 530 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 381 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 293 bp overlap

SMAD2_3 4 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 307 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 317 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 427 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 571 bp overlap

SMAD3 1 dataset

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 136 bp overlap

SMARCA4 7 datasets

ChIP CTV-1_DSG GSE128835.SMARCA4.CTV-1_DSG 380 bp overlap

ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 296 bp overlap

ChIP CTV-1_delQ GSE128835.SMARCA4.CTV-1_delQ 247 bp overlap

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 465 bp overlap

ChIP K-562 ENCSR643VTW.SMARCA4.K-562 221 bp overlap

ChIP K562 ENCFF316MCJ 413 bp overlap

ChIP K562 ENCFF506JCB 487 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 330 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 320 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 365 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 454 bp overlap

ChIP K562 ENCFF059YCJ 437 bp overlap

SPI1 10 datasets

ChIP BDMC_donorH GSE128834.SPI1.BDMC_donorH 133 bp overlap

ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 271 bp overlap

ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 250 bp overlap

ChIP K-562 GSE70482.SPI1.K-562 135 bp overlap

ChIP K-562 ENCSR000BGW.SPI1.K-562 57 bp overlap

ChIP K-562 GSE70482.SPI1.K-562 252 bp overlap

ChIP K-562 ENCSR000BGW.SPI1.K-562 174 bp overlap

ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 158 bp overlap

ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 253 bp overlap

ChIP Kasumi-1_SICTR GSE60130.SPI1.Kasumi-1_SICTR 281 bp overlap

STAG1 1 dataset

ChIP CHRF28811 ERP008568.STAG1.CHRF28811 174 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 652 bp overlap

SUPT5H 1 dataset

ChIP HCT-116_DMSO GSE138548.SUPT5H.HCT-116_DMSO 71 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 244 bp overlap

TAL1 4 datasets

ChIP CHRF28811 ERP008568.TAL1.CHRF28811 364 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 236 bp overlap

ChIP ME-1 GSE46044.TAL1.ME-1 300 bp overlap

ChIP TSU-1621MT GSE60477.TAL1.TSU-1621MT 480 bp overlap

TCF12 3 datasets

ChIP K562 ENCFF931DJY 384 bp overlap

ChIP Kasumi-1 GSE23730.TCF12.Kasumi-1 230 bp overlap

ChIP ME-1 GSE46044.TCF12.ME-1 388 bp overlap

TCF3 3 datasets

ChIP K-562 ENCSR970OJY.TCF3.K-562 254 bp overlap

ChIP K562 ENCFF319QZT 381 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 169 bp overlap

TFDP1 2 datasets

ChIP K562 ENCFF584VSB 460 bp overlap

ChIP K562 ENCFF584VSB 201 bp overlap

THAP12 1 dataset

ChIP K562 ENCFF453OQF 225 bp overlap

ZBTB16 1 dataset

ChIP KG-1_shEZH2 GSE109619.ZBTB16.KG-1_shEZH2 188 bp overlap

ZBTB7A 1 dataset

ChIP K-562 GSE103445.ZBTB7A.K-562 253 bp overlap

ZFP36 2 datasets

ChIP K-562 ENCSR776CYN.ZFP36.K-562 159 bp overlap

ChIP K562 ENCFF255RZG 297 bp overlap

ZSCAN29 1 dataset

ChIP K562 ENCFF797SOU 450 bp overlap