chr8 : 107,159,932 – 107,160,529

597 bp 112 TFs 1 linked gene

This 597 bp open chromatin element is linked to ENSG00000287289 and is bound by 112 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000287289		at TSS	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

112 transcription factors

AR 1 dataset

ChIP MCF-7 GSE48930.AR.MCF-7 171 bp overlap

ARNTL 1 dataset

ChIP U2OS GSE44236.ARNTL.U2OS 174 bp overlap

ASCL1 5 datasets

Motif DE_12h DE_12h-ASCL1_MA1100.3 8 bp overlap

ChIP NCI-H128 GSE69394.ASCL1.NCI-H128 168 bp overlap

ChIP NCI-H2107 GSE69394.ASCL1.NCI-H2107 178 bp overlap

ChIP NCI-H889 GSE69394.ASCL1.NCI-H889 173 bp overlap

ChIP SCLC_ASCLP GSE61197.ASCL1.SCLC_ASCLP 237 bp overlap

Ascl2 1 dataset

Motif DE_12h DE_12h-Ascl2_MA0816.1 10 bp overlap

BHLHE22 1 dataset

Motif DE_12h DE_12h-BHLHE22_MA1635.2 6 bp overlap

BRD1 1 dataset

ChIP RKO GSE47190.BRD1.RKO 143 bp overlap

BRD2 1 dataset

ChIP SUM159PT_JQ1 GSE116879.BRD2.SUM159PT_JQ1 204 bp overlap

BRD3 1 dataset

ChIP K-562_dilution-6-100 GSE140325.BRD3.K-562_dilution-6-100 107 bp overlap

BRD4 6 datasets

ChIP NCI-H1963 GSE145028.BRD4.NCI-H1963 471 bp overlap

ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 392 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 221 bp overlap

ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 206 bp overlap

ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 306 bp overlap

ChIP SUM159PT_30nMbortezomib_8h GSE87418.BRD4.SUM159PT_30nMbortezomib_8h 392 bp overlap

Bhlha15 1 dataset

Motif DE_12h DE_12h-Bhlha15_MA1472.3 8 bp overlap

CBX8 1 dataset

ChIP K-562 ENCSR000ATW.CBX8.K-562 65 bp overlap

CHD7 1 dataset

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 547 bp overlap

CREB1 1 dataset

ChIP A-549 ENCSR000BRB.CREB1.A-549 334 bp overlap

CREBBP 1 dataset

ChIP MCF-7 ERP000901.CREBBP.MCF-7 132 bp overlap

CRY1 1 dataset

ChIP U2OS GSE44236.CRY1.U2OS 268 bp overlap

E2F1 1 dataset

ChIP MCF-7 ENCFF692OYJ 597 bp overlap

EMSY 1 dataset

ChIP K562 ENCFF511ZZZ 192 bp overlap

EP300 1 dataset

ChIP Ishikawa ENCSR000BUE.EP300.Ishikawa 157 bp overlap

ERG 1 dataset

ChIP VCaP_ETOH GSE49091.ERG.VCaP_ETOH 143 bp overlap

ESR1 2 datasets

ChIP Ishikawa_ETV4-KO2_Mili GSE129803.ESR1.Ishikawa_ETV4-KO2_Mili 202 bp overlap

ChIP MCF-7_E2_45m GSE67295.ESR1.MCF-7_E2_45m 173 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 388 bp overlap

FERD3L 1 dataset

Motif DE_12h DE_12h-FERD3L_MA1485.1 14 bp overlap

FLI1 1 dataset

ChIP A-673_1_KRAB_GFP GSE106914.FLI1.A-673_1_KRAB_GFP 198 bp overlap

FOSL2 3 datasets

ChIP A-549 ENCSR448TVS.FOSL2.A-549 187 bp overlap

ChIP A549 ENCFF195CES 271 bp overlap

ChIP NPC_R1159Q GSE122631.FOSL2.NPC_R1159Q 224 bp overlap

FOXA1 3 datasets

ChIP A-549 ENCSR000BPX.FOXA1.A-549 302 bp overlap

ChIP A-549 ENCSR000BRD.FOXA1.A-549 237 bp overlap

ChIP HepG2 ENCFF740VZW 285 bp overlap

FOXA2 3 datasets

ChIP DE DE-FOXA2-1 334 bp overlap

ChIP HepG2 ENCFF570ABM 141 bp overlap

ChIP liver_CARN1618 ERP008682.FOXA2.liver_CARN1618 321 bp overlap

FOXF1 1 dataset

ChIP GIST-T1 GSE106624.FOXF1.GIST-T1 210 bp overlap

GABPA 1 dataset

ChIP VCaP GSE49091.GABPA.VCaP 188 bp overlap

GATA1::TAL1 1 dataset

Motif DE_12h DE_12h-GATA1TAL1_MA0140.3 17 bp overlap

GATA3 2 datasets

ChIP A-549 ENCSR000BTI.GATA3.A-549 161 bp overlap

ChIP A549 ENCFF226FVV 362 bp overlap

HDAC2 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC2.RH4_DMSO-6H 234 bp overlap

HIF1A 1 dataset

ChIP U2OS_trough_DMOG GSE85096.HIF1A.U2OS_trough_DMOG 342 bp overlap

HNF4A 1 dataset

ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 207 bp overlap

JUN 1 dataset

ChIP DE_D2 S02-DE-d2-JUN-exp1 248 bp overlap

MAF 1 dataset

Motif DE_12h DE_12h-MAF_MA1520.2 13 bp overlap

MAFB 1 dataset

ChIP islet ERP004003.MAFB.islet 554 bp overlap

MAFG 2 datasets

ChIP K-562 ENCSR818DQV.MAFG.K-562 552 bp overlap

ChIP K562 ENCFF455EEO 415 bp overlap

MAFK 1 dataset

ChIP A549 ENCFF371EPR 349 bp overlap

MAX 3 datasets

ChIP NCI-H128 GSE41105.MAX.NCI-H128 435 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 161 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 170 bp overlap

MEIS1 1 dataset

Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap

MEIS2 1 dataset

Motif DE_12h DE_12h-MEIS2_MA0774.1 8 bp overlap

MEIS3 1 dataset

Motif DE_12h DE_12h-MEIS3_MA0775.2 7 bp overlap

MSANTD3 1 dataset

Motif DE_12h DE_12h-MSANTD3_MA1523.2 7 bp overlap

MSC 1 dataset

Motif DE_12h DE_12h-MSC_MA0665.1 10 bp overlap

MTA2 1 dataset

ChIP RH4 GSE155861.MTA2.RH4 395 bp overlap

MYF5 1 dataset

Motif DE_12h DE_12h-MYF5_MA1641.2 8 bp overlap

MYF6 1 dataset

Motif DE_12h DE_12h-MYF6_MA0667.1 10 bp overlap

MYOD1 2 datasets

Motif DE_12h DE_12h-MYOD1_MA0499.3 9 bp overlap

ChIP RH4 GSE83726.MYOD1.RH4 191 bp overlap

MYOG 2 datasets

Motif DE_12h DE_12h-MYOG_MA0500.3 8 bp overlap

ChIP RH4_DMSO-6H GSE116344.MYOG.RH4_DMSO-6H 423 bp overlap

NANOG 2 datasets

ChIP WA01 ERP004238.NANOG.WA01 226 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 230 bp overlap

NCOA3 1 dataset

ChIP MCF-7_E2 ERP000901.NCOA3.MCF-7_E2 263 bp overlap

NEUROD1 5 datasets

ChIP D283-Med GSE92582.NEUROD1.D283-Med 325 bp overlap

ChIP D283-Med_shNEUROD1-1579 GSE92582.NEUROD1.D283-Med_shNEUROD1-1579 342 bp overlap

ChIP D341-Med_shGFP GSE92582.NEUROD1.D341-Med_shGFP 565 bp overlap

ChIP D341-Med_shNEUROD1-1154 GSE92582.NEUROD1.D341-Med_shNEUROD1-1154 477 bp overlap

ChIP D341-Med_shNEUROD1-1579 GSE92582.NEUROD1.D341-Med_shNEUROD1-1579 524 bp overlap

NFE2 1 dataset

ChIP K-562 ENCSR000FCC.NFE2.K-562 129 bp overlap

NFE2L2 1 dataset

ChIP A-549 GSE113497.NFE2L2.A-549 251 bp overlap

NFIA 1 dataset

Motif DE_12h DE_12h-NFIA_MA0670.2 6 bp overlap

NFIC 3 datasets

ChIP Ishikawa ENCFF029AAD 381 bp overlap

ChIP Ishikawa ENCSR000BUT.NFIC.Ishikawa 218 bp overlap

ChIP K-562 ENCSR796ITY.NFIC.K-562 226 bp overlap

NFIX 1 dataset

Motif DE_12h DE_12h-NFIX_MA0671.2 6 bp overlap

NHLH1 1 dataset

Motif DE_12h DE_12h-NHLH1_MA0048.3 9 bp overlap

NKX2-5 1 dataset

ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 195 bp overlap

NR1H3 1 dataset

ChIP THP-1 GSE28319.NR1H3.THP-1 236 bp overlap

NR3C1 5 datasets

ChIP A-549 ENCSR000BHG.NR3C1.A-549 133 bp overlap

ChIP A-549 ENCSR000BHF.NR3C1.A-549 463 bp overlap

ChIP A-549 ENCSR000BJR.NR3C1.A-549 457 bp overlap

ChIP A-549 ENCSR000BHG.NR3C1.A-549 314 bp overlap

ChIP A-549 ENCSR000BHE.NR3C1.A-549 203 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA1993.2 6 bp overlap

Nr2e3 1 dataset

Motif DE_12h DE_12h-Nr2e3_MA0164.2 6 bp overlap

ONECUT1 2 datasets

ChIP Hep-G2 ENCSR956OSX.ONECUT1.Hep-G2 155 bp overlap

ChIP HepG2 ENCFF243FIR 282 bp overlap

Olig2 1 dataset

Motif DE_12h DE_12h-Olig2_MA1997.2 6 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 373 bp overlap

POLR2A 1 dataset

ChIP gastroesophageal sphincter ENCFF070PCA 321 bp overlap

POU2F2 1 dataset

ChIP HNPC_UNDIF GSE74814.POU2F2.HNPC_UNDIF 148 bp overlap

POU4F2 2 datasets

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 270 bp overlap

ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 126 bp overlap

Ptf1A 1 dataset

Motif DE_12h DE_12h-Ptf1A_MA1619.2 8 bp overlap

RELA 2 datasets

ChIP FaDu_LPS GSE132018.RELA.FaDu_LPS 83 bp overlap

ChIP IMR-90_TNF GSE43070.RELA.IMR-90_TNF 72 bp overlap

REST 1 dataset

ChIP hippocampus GSE144226.REST.hippocampus 239 bp overlap

RUNX1 1 dataset

ChIP VCaP_DHT24H GSE58428.RUNX1.VCaP_DHT24H 57 bp overlap

RXRA 2 datasets

ChIP Hep-G2 ENCSR000BHU.RXRA.Hep-G2 117 bp overlap

ChIP liver ENCFF807CIA 355 bp overlap

RXRB 1 dataset

ChIP HepG2 ENCFF539ZAY 343 bp overlap

SMAD2-3 2 datasets

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 477 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 421 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 391 bp overlap

SMAD3 1 dataset

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 136 bp overlap

SMARCA4 14 datasets

ChIP A-549_AG15677 GSE132290.SMARCA4.A-549_AG15677 94 bp overlap

ChIP A-549_AG15678 GSE132290.SMARCA4.A-549_AG15678 110 bp overlap

ChIP A-549_AG15684 GSE132290.SMARCA4.A-549_AG15684 355 bp overlap

ChIP A-549_AG15685 GSE132290.SMARCA4.A-549_AG15685 447 bp overlap

ChIP A-549_AG15688 GSE132290.SMARCA4.A-549_AG15688 391 bp overlap

ChIP A-549_AG15720 GSE132290.SMARCA4.A-549_AG15720 54 bp overlap

ChIP A-549_AG15721 GSE132290.SMARCA4.A-549_AG15721 156 bp overlap

ChIP A-549_AG15722 GSE132290.SMARCA4.A-549_AG15722 83 bp overlap

ChIP A-549_AG15723 GSE132290.SMARCA4.A-549_AG15723 144 bp overlap

ChIP A-549_AG15724 GSE132290.SMARCA4.A-549_AG15724 222 bp overlap

ChIP A-549_AG15725 GSE132290.SMARCA4.A-549_AG15725 105 bp overlap

ChIP NPC_K755R-siAP GSE122631.SMARCA4.NPC_K755R-siAP 297 bp overlap

ChIP NPC_K755R-siCT GSE122631.SMARCA4.NPC_K755R-siCT 211 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 263 bp overlap

SNAI2 1 dataset

ChIP SMS-CTR_D48 GSE137168.SNAI2.SMS-CTR_D48 352 bp overlap

SOX2 2 datasets

ChIP HNSC GSE69479.SOX2.HNSC 597 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 308 bp overlap

SOX8 1 dataset

ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 201 bp overlap

SP1 1 dataset

ChIP A-549 ENCSR000BPE.SP1.A-549 283 bp overlap

STAT1 1 dataset

Motif DE_12h DE_12h-STAT1_MA0137.4 9 bp overlap

STAT1::STAT2 1 dataset

Motif DE_12h DE_12h-STAT1STAT2_MA0517.2 13 bp overlap

STAT3 3 datasets

ChIP MDA-MB-157_EtOH GSE85579.STAT3.MDA-MB-157_EtOH 190 bp overlap

ChIP T-47D_JC4757 GSE126004.STAT3.T-47D_JC4757 195 bp overlap

ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 185 bp overlap

Spz1 1 dataset

Motif DE_12h DE_12h-Spz1_MA0111.1 11 bp overlap

Stat4 1 dataset

Motif DE_12h DE_12h-Stat4_MA0518.2 10 bp overlap

T 1 dataset

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 183 bp overlap

TCF12 1 dataset

ChIP A-549 ENCSR000BQQ.TCF12.A-549 402 bp overlap

TEAD1 1 dataset

ChIP CCLP1 GSE62272.TEAD1.CCLP1 364 bp overlap

TEAD4 1 dataset

ChIP hMSC-TERT4 GSE140782.TEAD4.hMSC-TERT4 243 bp overlap

TFAP2C 1 dataset

ChIP HCC1954 GSE126897.TFAP2C.HCC1954 467 bp overlap

TFAP4::FLI1 1 dataset

Motif DE_12h DE_12h-TFAP4FLI1_MA1967.2 14 bp overlap

THRB 1 dataset

Motif DE_12h DE_12h-THRB_MA1575.2 17 bp overlap

TWIST1 1 dataset

ChIP SHEP-21N GSE80151.TWIST1.SHEP-21N 151 bp overlap

Tcf12 1 dataset

Motif DE_12h DE_12h-Tcf12_MA0521.3 6 bp overlap

Tcf21 1 dataset

Motif DE_12h DE_12h-Tcf21_MA0832.2 10 bp overlap

Twist2 1 dataset

Motif DE_12h DE_12h-Twist2_MA0633.3 6 bp overlap

ZIC1 1 dataset

Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap

ZIC4 1 dataset

Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap

ZNF189 1 dataset

Motif DE_12h DE_12h-ZNF189_MA1725.2 9 bp overlap

ZNF316 1 dataset

ChIP K562 ENCFF838QCD 356 bp overlap

ZNF454 1 dataset

Motif DE_12h DE_12h-ZNF454_MA1712.2 17 bp overlap

ZNF462 1 dataset

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 143 bp overlap

ZNF532 2 datasets

ChIP NMC24335 GSE96775.ZNF532.NMC24335 181 bp overlap

ChIP NMC24335 GSE96775.ZNF532.NMC24335 205 bp overlap

ZNF768 1 dataset

Motif DE_12h DE_12h-ZNF768_MA1731.2 9 bp overlap

ZNF93 1 dataset

Motif DE_12h DE_12h-ZNF93_MA1721.2 14 bp overlap

ZSCAN21 1 dataset

Motif DE_12h DE_12h-ZSCAN21_MA2336.1 7 bp overlap

Zic1::Zic2 1 dataset

Motif DE_12h DE_12h-Zic1Zic2_MA1628.2 7 bp overlap

Zic2 1 dataset

Motif DE_12h DE_12h-Zic2_MA1629.2 9 bp overlap

Zic3 1 dataset

Motif DE_12h DE_12h-Zic3_MA0697.3 7 bp overlap