chr1:153,966,072–153,966,650

chr1 : 153,966,072 – 153,966,650

578 bp 97 TFs 6 linked genes

This 578 bp open chromatin element is linked to 6 target genes and is bound by 97 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000273026		at TSS	At TSS	Proximity
CREB3L4		1.2 kb	Proximal	Proximity
ENSG00000282386		1.7 kb	Proximal	Proximity
SLC39A1		2.6 kb	Proximal	Proximity
CRTC2		7.5 kb	Proximal	Proximity
ENSG00000285779		9.2 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

97 transcription factors

ARID4B 1 dataset

ChIP K562 ENCFF791HBV 207 bp overlap

ChIP GM12878 ENCSR014YCR.ATF7.GM12878 286 bp overlap

ChIP GM12878 ENCFF954REE 57 bp overlap

ChIP THP-1_DMSO GSE138084.BRD2.THP-1_DMSO 351 bp overlap

ChIP HEK293T GSE39579.BRD3.HEK293T 144 bp overlap

BRD4 10 datasets

ChIP HAP1 GSE108387.BRD4.HAP1 293 bp overlap

ChIP MCF-7_ARID1A-KO GSE123284.BRD4.MCF-7_ARID1A-KO 321 bp overlap

ChIP MCF-7_ARID1A-KO_4-OHT GSE123284.BRD4.MCF-7_ARID1A-KO_4-OHT 314 bp overlap

ChIP MCF-7_parental GSE123284.BRD4.MCF-7_parental 259 bp overlap

ChIP MCF-7_parental_4-hydroxytamoxifen GSE123284.BRD4.MCF-7_parental_4-hydroxytamoxifen 294 bp overlap

ChIP MOLM-14_IBET GSE65138.BRD4.MOLM-14_IBET 165 bp overlap

ChIP MV4-11_DMSO GSE71776.BRD4.MV4-11_DMSO 77 bp overlap

ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 216 bp overlap

ChIP SUM159PT_Dox_48h GSE87418.BRD4.SUM159PT_Dox_48h 72 bp overlap

ChIP SUM159PT_shMYC_DMSO_48h GSE87418.BRD4.SUM159PT_shMYC_DMSO_48h 89 bp overlap

ChIP MCF-7 ENCSR360JOC.CHD1.MCF-7 77 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 283 bp overlap

CTCF 3 datasets

ChIP MCF-7 ENCSR560BUE.CTCF.MCF-7 52 bp overlap

ChIP NCI-H929 ENCFF305JAB 311 bp overlap

ChIP NCI-H929 ENCFF305JAB 400 bp overlap

ChIP MCF-7 ENCSR000EWX.E2F1.MCF-7 260 bp overlap

E2F6 4 datasets

ChIP A-549 ENCSR000BTC.E2F6.A-549 123 bp overlap

ChIP H1 ENCFF785DWK 391 bp overlap

ChIP K-562 ENCSR000EWJ.E2F6.K-562 263 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 249 bp overlap

ChIP GM12878 ENCFF266FYW 257 bp overlap

ELF3 2 datasets

ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 156 bp overlap

ChIP PDAC_SHCTR GSE64557.ELF3.PDAC_SHCTR 152 bp overlap

EP300 1 dataset

ChIP HeLa-S3 ENCFF089VPQ 89 bp overlap

ChIP Jurkat GSE49091.ERG.Jurkat 155 bp overlap

ETS1 2 datasets

ChIP CTV-1_DSG GSE128835.ETS1.CTV-1_DSG 108 bp overlap

ChIP CTV-1_DSG_SPI1-mut GSE128835.ETS1.CTV-1_DSG_SPI1-mut 164 bp overlap

ETV6 2 datasets

ChIP GM12878 GSE97661.ETV6.GM12878 82 bp overlap

ChIP GM12878 ENCSR626VUC.ETV6.GM12878 128 bp overlap

ChIP CTV-1_DSG_SPI1-mut GSE128835.FLI1.CTV-1_DSG_SPI1-mut 98 bp overlap

FOXA1 13 datasets

ChIP 22Rv1_CST GSE129951.FOXA1.22Rv1_CST 198 bp overlap

ChIP 22Rv1_CST_Crispr GSE123618.FOXA1.22Rv1_CST_Crispr 70 bp overlap

ChIP 22Rv1_CST_Crispr-36 GSE123618.FOXA1.22Rv1_CST_Crispr-36 52 bp overlap

ChIP 22Rv1_CST_Crispr_WT3 GSE123618.FOXA1.22Rv1_CST_Crispr_WT3 55 bp overlap

ChIP 22Rv1_TFS_Crispr_WT3 GSE123618.FOXA1.22Rv1_TFS_Crispr_WT3 73 bp overlap

ChIP 22Rv1_i176m_CST GSE123618.FOXA1.22Rv1_i176m_CST 62 bp overlap

ChIP LNCaP_TFS GSE123618.FOXA1.LNCaP_TFS 50 bp overlap

ChIP T-47D_CR3flp GSE99479.FOXA1.T-47D_CR3flp 122 bp overlap

ChIP T-47D_shRNF2_24h GSE137579.FOXA1.T-47D_shRNF2_24h 59 bp overlap

ChIP ZR-75-1_vehicle_ab2 GSE112969.FOXA1.ZR-75-1_vehicle_ab2 58 bp overlap

ChIP breast-cancer_Veh-2856 GSE128018.FOXA1.breast-cancer_Veh-2856 119 bp overlap

ChIP breast-cancer_Veh-2860 GSE128018.FOXA1.breast-cancer_Veh-2860 56 bp overlap

ChIP breast_tumor_Male_19 GSE104399.FOXA1.breast_tumor_Male_19 157 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 200 bp overlap

ChIP DE DE-FOXA2-2 247 bp overlap

GATA3 1 dataset

ChIP Jurkat GSE76181.GATA3.Jurkat 161 bp overlap

GATA4 4 datasets

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 212 bp overlap

ChIP DE DE-GATA4-1 431 bp overlap

ChIP DE DE-GATA4-2 514 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 265 bp overlap

GATA6 8 datasets

ChIP DE DE-GATA6-1 487 bp overlap

ChIP DE DE-GATA6-2 508 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 415 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 259 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 489 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 280 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 280 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 332 bp overlap

ChIP HepG2 ENCFF472INF 283 bp overlap

HCFC1 1 dataset

ChIP HeLa-S3 ENCFF159VGJ 80 bp overlap

HDAC2 2 datasets

ChIP K-562 ENCSR893WSB.HDAC2.K-562 246 bp overlap

ChIP K-562 ENCSR075HTM.HDAC2.K-562 217 bp overlap

HDGF 3 datasets

ChIP GM12878 ENCFF653WYI 377 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 277 bp overlap

ChIP K-562 ENCSR197ALX.HDGF.K-562 306 bp overlap

HMGXB4 1 dataset

ChIP Hep-G2 ENCSR174GOO.HMGXB4.Hep-G2 60 bp overlap

HNRNPLL 1 dataset

ChIP K-562 ENCSR112RNT.HNRNPLL.K-562 206 bp overlap

IKZF1 1 dataset

ChIP K-562 ENCSR395HWC.IKZF1.K-562 186 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 144 bp overlap

ChIP GM12878 ENCSR897MMC.JUNB.GM12878 158 bp overlap

ChIP OCI-AML-3 GSE133516.KAT7.OCI-AML-3 220 bp overlap

KDM5B 1 dataset

ChIP K-562 ENCSR000AQA.KDM5B.K-562 102 bp overlap

KMT2A 5 datasets

ChIP HEK293T_C-term_C49 GSE90762.KMT2A.HEK293T_C-term_C49 348 bp overlap

ChIP HEK293T_N-term_C104 GSE90762.KMT2A.HEK293T_N-term_C104 421 bp overlap

ChIP KOPN-8 GSE83671.KMT2A.KOPN-8 155 bp overlap

ChIP RCH-ACV GSE83671.KMT2A.RCH-ACV 578 bp overlap

ChIP blood_cord GSE83671.KMT2A.blood_cord 85 bp overlap

L3MBTL2 4 datasets

ChIP HEK293T ENCFF482NJV 533 bp overlap

ChIP HEK293T ENCSR862PNL.L3MBTL2.HEK293T 311 bp overlap

ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 387 bp overlap

ChIP K562 ENCFF320EQC 293 bp overlap

ChIP CD4_Th1 GSE72266.MAF.CD4_Th1 283 bp overlap

ChIP HeLa-S3 ENCFF398RFF 385 bp overlap

ChIP HeLa-S3 ENCFF398RFF 161 bp overlap

ChIP K-562 ENCSR000EFV.MAX.K-562 142 bp overlap

ChIP K562 ENCFF524IJO 397 bp overlap

ChIP K562 ENCFF524IJO 245 bp overlap

ChIP GM12878 GSE93080.MED1.GM12878 205 bp overlap

MEIS2 1 dataset

ChIP K562 ENCFF320GSD 180 bp overlap

ChIP OCI-AML-3_DMSO GSE129636.MEN1.OCI-AML-3_DMSO 246 bp overlap

ChIP K562 ENCFF140CEX 529 bp overlap

MITF 2 datasets

ChIP K-562 ENCSR797SWM.MITF.K-562 357 bp overlap

ChIP K562 ENCFF731XJJ 425 bp overlap

MLLT1 3 datasets

ChIP GM12878 ENCFF995GXC 262 bp overlap

ChIP K-562 ENCSR107GRP.MLLT1.K-562 133 bp overlap

ChIP K562 ENCFF074XRJ 162 bp overlap

MLLT1_FKB 2 datasets

ChIP MV4-11 GSE82116.MLLT1_FKB.MV4-11 245 bp overlap

ChIP MV4-11 GSE82116.MLLT1_FKB.MV4-11 59 bp overlap

ChIP CD4_TH2 GSE72266.MYB.CD4_TH2 81 bp overlap

ChIP CD4_Th1 GSE72266.MYB.CD4_Th1 155 bp overlap

ChIP Jurkat GSE59657.MYB.Jurkat 139 bp overlap

ChIP P493-6_scramble-shRNA GSE101853.MYC.P493-6_scramble-shRNA 174 bp overlap

ChIP GM12878 ENCSR278SQL.NBN.GM12878 283 bp overlap

ChIP GM12878 ENCSR278SQL.NBN.GM12878 53 bp overlap

NELFA 1 dataset

ChIP K-562_HS GSE112379.NELFA.K-562_HS 132 bp overlap

NEUROD1 1 dataset

ChIP D283-Med GSE92582.NEUROD1.D283-Med 179 bp overlap

ChIP GM12878 ENCSR000BRN.NFIC.GM12878 112 bp overlap

ChIP HEK293 ENCFF875BDB 154 bp overlap

ChIP HCT-116_ab20662 GSE97527.PAF1.HCT-116_ab20662 72 bp overlap

ChIP GM12891 ENCSR000BJH.PAX5.GM12891 140 bp overlap

PHIP 2 datasets

ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 301 bp overlap

ChIP HEK293_ab833 GSE101646.PHIP.HEK293_ab833 99 bp overlap

PKNOX1 1 dataset

ChIP GM12878 ENCSR711XNY.PKNOX1.GM12878 245 bp overlap

POLR2A 5 datasets

ChIP GM12891 ENCFF379FCI 226 bp overlap

ChIP GM19193 ENCFF599VTO 446 bp overlap

ChIP HCT116 ENCFF849NGT 399 bp overlap

ChIP MCF-7 ENCFF164XWP 158 bp overlap

ChIP Raji ENCFF613VGX 521 bp overlap

ChIP GM12878 ENCSR785OKZ.RB1.GM12878 210 bp overlap

RBBP5 1 dataset

ChIP K562 ENCFF070CVK 578 bp overlap

RCOR1 1 dataset

ChIP HeLa-S3 ENCFF471KYI 371 bp overlap

ChIP HepG2 ENCFF232LZK 500 bp overlap

ChIP HepG2 ENCFF232LZK 273 bp overlap

ChIP GM12878 ENCSR387QUV.RELB.GM12878 259 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 89 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 274 bp overlap

SMAD2_3 1 dataset

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 210 bp overlap

SMAD3 1 dataset

ChIP Hep-G2 ENCSR005GZH.SMAD3.Hep-G2 58 bp overlap

SMARCA4 6 datasets

ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-K785R 300 bp overlap

ChIP CTV-1_DSG_SPI1-mut GSE128835.SMARCA4.CTV-1_DSG_SPI1-mut 222 bp overlap

ChIP CTV-1_FLAG GSE128835.SMARCA4.CTV-1_FLAG 118 bp overlap

ChIP CTV-1_delA GSE128835.SMARCA4.CTV-1_delA 195 bp overlap

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 288 bp overlap

ChIP TTC-1240_SMARCB1-FL GSE124903.SMARCA4.TTC-1240_SMARCB1-FL 56 bp overlap

SMARCC1 1 dataset

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 250 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 301 bp overlap

ChIP HeLa-S3 ENCFF992MML 77 bp overlap

SPI1 6 datasets

ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 106 bp overlap

ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 61 bp overlap

ChIP EM-3 GSE128834.SPI1.EM-3 54 bp overlap

ChIP GM12878 ENCFF134LCP 79 bp overlap

ChIP GM12891 ENCFF563IUT 55 bp overlap

ChIP HL-60 ENCFF645GBT 95 bp overlap

SREBP2 1 dataset

ChIP monocyte GSE129202.SREBP2.monocyte 289 bp overlap

TAL1 2 datasets

ChIP MOLT-3 GSE59657.TAL1.MOLT-3 134 bp overlap

ChIP PRIMA2 GSE33850.TAL1.PRIMA2 55 bp overlap

TARDBP 1 dataset

ChIP GM12878 ENCSR412QBS.TARDBP.GM12878 214 bp overlap

ChIP HeLa-S3 ENCFF715NNJ 142 bp overlap

TBX21 1 dataset

ChIP GM12878 ENCSR739IHN.TBX21.GM12878 225 bp overlap

TEAD1 1 dataset

ChIP K562 ENCFF254RJL 160 bp overlap

TEAD4 1 dataset

ChIP K562 ENCFF673NIK 318 bp overlap

ChIP K562 ENCFF697ABG 317 bp overlap

ChIP K562 ENCFF728FRA 471 bp overlap

TRIM22 1 dataset

ChIP GM12878 ENCSR637QAM.TRIM22.GM12878 266 bp overlap

XRCC5 1 dataset

ChIP K-562 GSE120104.XRCC5.K-562 162 bp overlap

ChIP Hep-G2_NC GSE120104.YY1.Hep-G2_NC 294 bp overlap

ChIP K562 ENCFF660QRE 296 bp overlap

ZBTB17 1 dataset

ChIP HEK293 ENCFF865LIO 372 bp overlap

ZBTB20 1 dataset

ChIP HEK293 ENCFF524ADK 214 bp overlap

ZBTB38 1 dataset

ChIP HepG2 ENCFF875UQX 509 bp overlap

ZBTB40 2 datasets

ChIP GM12878 ENCFF346DYM 243 bp overlap

ChIP K-562 ENCSR237VLT.ZBTB40.K-562 242 bp overlap

ZBTB6 2 datasets

ChIP HEK293 ENCFF881ECZ 128 bp overlap

ChIP HEK293 ENCSR619OUC.ZBTB6.HEK293 146 bp overlap

ZBTB7A 1 dataset

ChIP K-562 GSE103445.ZBTB7A.K-562 197 bp overlap

ChIP HEK293 ENCSR417VWF.ZEB2.HEK293 281 bp overlap

ChIP HeLa-S3 ENCSR855WKQ.ZHX1.HeLa-S3 53 bp overlap

ZNF24 4 datasets

ChIP K-562 ENCSR695EQB.ZNF24.K-562 79 bp overlap

ChIP K562 ENCFF877JCX 225 bp overlap

ChIP MCF-7 ENCFF861XIL 123 bp overlap

ChIP MCF-7 ENCSR503VTG.ZNF24.MCF-7 75 bp overlap

ZNF281 1 dataset

ChIP K562 ENCFF594VNM 335 bp overlap

ZNF335 1 dataset

ChIP HEK293 ENCFF784SLD 387 bp overlap

ZNF366 1 dataset

ChIP HEK293 ENCSR106EBH.ZNF366.HEK293 387 bp overlap

ZNF677 2 datasets

ChIP HEK293 ENCFF220HCQ 170 bp overlap

ChIP HEK293 ENCSR279KDC.ZNF677.HEK293 217 bp overlap

ZNF784 1 dataset

ChIP HepG2 ENCFF265UCH 263 bp overlap