chr4 : 73,943,435 – 73,943,898

463 bp 135 TFs 1 linked gene

This 463 bp open chromatin element is linked to CXCL1P1 and is bound by 135 transcription factors.

Linked Genes

1 gene

Gene	Expression	Dist. to TSS	Distance	Link type
CXCL1P1		425 bp	At TSS	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

135 transcription factors

ALX3 1 dataset

Motif ES_0h ES_0h-ALX3_MA0634.2 6 bp overlap

ARGFX 1 dataset

Motif ES_0h ES_0h-ARGFX_MA1463.2 8 bp overlap

ASH2L 1 dataset

ChIP H1 ENCFF399KAM 181 bp overlap

ATF2 1 dataset

ChIP WA01 ENCSR000BQU.ATF2.WA01 185 bp overlap

BARX2 1 dataset

Motif ES_0h ES_0h-BARX2_MA1471.2 9 bp overlap

BCL11A 1 dataset

ChIP WA01 ENCSR000BIP.BCL11A.WA01 126 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 288 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 282 bp overlap

ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 250 bp overlap

CHD7 3 datasets

ChIP H1 ENCFF126NLU 405 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 193 bp overlap

ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 241 bp overlap

CREB1 1 dataset

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 233 bp overlap

CTBP2 1 dataset

ChIP WA01 ENCSR000EUO.CTBP2.WA01 266 bp overlap

DMRTA2 1 dataset

Motif ES_0h ES_0h-DMRTA2_MA1478.2 6 bp overlap

DMRTC2 1 dataset

Motif ES_0h ES_0h-DMRTC2_MA1479.2 11 bp overlap

DRGX 1 dataset

Motif ES_0h ES_0h-DRGX_MA1481.2 6 bp overlap

EMX1 1 dataset

Motif ES_0h ES_0h-EMX1_MA0612.3 6 bp overlap

EMX2 1 dataset

Motif ES_0h ES_0h-EMX2_MA0886.2 6 bp overlap

EN1 1 dataset

Motif ES_0h ES_0h-EN1_MA0027.3 6 bp overlap

EN2 1 dataset

Motif ES_0h ES_0h-EN2_MA0642.3 7 bp overlap

EP300 3 datasets

ChIP WA01 ENCSR000BKK.EP300.WA01 149 bp overlap

ChIP hESC GSE17917.EP300.hESC 274 bp overlap

ChIP osteoblast ENCSR000AUD.EP300.osteoblast 237 bp overlap

ESX1 1 dataset

Motif ES_0h ES_0h-ESX1_MA0644.3 7 bp overlap

ETV2::HOXB13 2 datasets

Motif DE_12h DE_12h-ETV2HOXB13_MA1943.2 13 bp overlap

Motif ES_0h ES_0h-ETV2HOXB13_MA1943.2 13 bp overlap

EVX1 1 dataset

Motif ES_0h ES_0h-EVX1_MA0887.2 6 bp overlap

EVX2 1 dataset

Motif ES_0h ES_0h-EVX2_MA0888.2 6 bp overlap

EZH2 7 datasets

ChIP SF8628 GSE94834.EZH2.SF8628 463 bp overlap

ChIP SK-N-MC ENCFF674XUJ 294 bp overlap

ChIP astrocyte ENCFF365JTP 64 bp overlap

ChIP astrocyte ENCSR000ARR.EZH2.astrocyte 248 bp overlap

ChIP hepatocyte ENCFF552DZB 164 bp overlap

ChIP neural progenitor cell ENCFF018MKA 158 bp overlap

ChIP neural progenitor cell ENCFF472NFV 162 bp overlap

FOXA2 1 dataset

Motif ES_0h ES_0h-FOXA2_MA0047.4 8 bp overlap

FOXA3 1 dataset

Motif ES_0h ES_0h-FOXA3_MA1683.2 7 bp overlap

FOXB1 1 dataset

Motif ES_0h ES_0h-FOXB1_MA0845.1 11 bp overlap

FOXC1 1 dataset

Motif ES_0h ES_0h-FOXC1_MA0032.2 11 bp overlap

FOXC2 1 dataset

Motif ES_0h ES_0h-FOXC2_MA0846.2 11 bp overlap

FOXD2 1 dataset

Motif ES_0h ES_0h-FOXD2_MA0847.4 11 bp overlap

FOXD3 1 dataset

Motif ES_0h ES_0h-FOXD3_MA0041.3 14 bp overlap

FOXI1 1 dataset

Motif ES_0h ES_0h-FOXI1_MA0042.2 7 bp overlap

FOXN3 1 dataset

Motif ES_0h ES_0h-FOXN3_MA1489.1 8 bp overlap

FOXO1::ELF1 1 dataset

Motif ES_0h ES_0h-FOXO1ELF1_MA1953.2 13 bp overlap

FOXP1 1 dataset

Motif ES_0h ES_0h-FOXP1_MA0481.4 7 bp overlap

FOXP4 1 dataset

Motif ES_0h ES_0h-FOXP4_MA2117.1 7 bp overlap

FOXS1 1 dataset

Motif ES_0h ES_0h-FOXS1_MA2118.1 8 bp overlap

Foxj3 1 dataset

Motif ES_0h ES_0h-Foxj3_MA0851.2 9 bp overlap

Foxl2 1 dataset

Motif ES_0h ES_0h-Foxl2_MA1607.2 10 bp overlap

GATA6 4 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 336 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 134 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 229 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 313 bp overlap

GBX1 1 dataset

Motif ES_0h ES_0h-GBX1_MA0889.2 7 bp overlap

GSX1 1 dataset

Motif ES_0h ES_0h-GSX1_MA0892.2 6 bp overlap

GSX2 1 dataset

Motif ES_0h ES_0h-GSX2_MA0893.3 7 bp overlap

HDAC2 2 datasets

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 315 bp overlap

HNF1A 1 dataset

Motif ES_0h ES_0h-HNF1A_MA0046.3 13 bp overlap

HNF1B 1 dataset

Motif ES_0h ES_0h-HNF1B_MA0153.2 13 bp overlap

HNF4A 1 dataset

Motif ES_0h ES_0h-HNF4A_MA1494.2 14 bp overlap

HOXA1 1 dataset

Motif ES_0h ES_0h-HOXA1_MA1495.2 6 bp overlap

HOXA2 1 dataset

Motif ES_0h ES_0h-HOXA2_MA0900.3 6 bp overlap

HOXA3 1 dataset

Motif ES_0h ES_0h-HOXA3_MA2119.1 7 bp overlap

HOXB1 1 dataset

Motif ES_0h ES_0h-HOXB1_MA2093.1 7 bp overlap

HOXB2 1 dataset

Motif ES_0h ES_0h-HOXB2_MA0902.3 6 bp overlap

HOXB3 1 dataset

Motif ES_0h ES_0h-HOXB3_MA0903.2 6 bp overlap

HOXB5 1 dataset

Motif ES_0h ES_0h-HOXB5_MA0904.3 6 bp overlap

HOXC8 1 dataset

Motif ES_0h ES_0h-HOXC8_MA1505.2 6 bp overlap

HOXD3 1 dataset

Motif ES_0h ES_0h-HOXD3_MA0912.2 8 bp overlap

IKZF2 1 dataset

Motif ES_0h ES_0h-IKZF2_MA2326.1 6 bp overlap

ISX 1 dataset

Motif ES_0h ES_0h-ISX_MA0654.2 6 bp overlap

JUN 1 dataset

ChIP HUES-8 GSE109524.JUN.HUES-8 322 bp overlap

LBX1 1 dataset

Motif ES_0h ES_0h-LBX1_MA0618.2 7 bp overlap

LHX5 1 dataset

Motif ES_0h ES_0h-LHX5_MA1519.2 7 bp overlap

LHX6 1 dataset

Motif ES_0h ES_0h-LHX6_MA0658.2 8 bp overlap

LHX9 1 dataset

Motif ES_0h ES_0h-LHX9_MA0701.3 7 bp overlap

LMX1A 1 dataset

Motif ES_0h ES_0h-LMX1A_MA0702.3 7 bp overlap

LMX1B 1 dataset

Motif ES_0h ES_0h-LMX1B_MA0703.3 8 bp overlap

Lhx4 1 dataset

Motif ES_0h ES_0h-Lhx4_MA0704.2 6 bp overlap

Lhx8 1 dataset

Motif ES_0h ES_0h-Lhx8_MA0705.2 6 bp overlap

MEOX1 1 dataset

Motif ES_0h ES_0h-MEOX1_MA0661.2 7 bp overlap

MEOX2 1 dataset

Motif ES_0h ES_0h-MEOX2_MA0706.2 7 bp overlap

MIXL1 1 dataset

Motif ES_0h ES_0h-MIXL1_MA0662.2 6 bp overlap

MNX1 1 dataset

Motif ES_0h ES_0h-MNX1_MA0707.3 6 bp overlap

NANOG 11 datasets

ChIP GM23338 ENCFF065NZG 298 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 188 bp overlap

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 442 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 324 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 264 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 463 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 409 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 444 bp overlap

ChIP hESC GSE20650.NANOG.hESC 234 bp overlap

ChIP hESC GSE18292.NANOG.hESC 262 bp overlap

NIPBL 1 dataset

ChIP WA09 GSE105028.NIPBL.WA09 294 bp overlap

NKX6-2 1 dataset

Motif ES_0h ES_0h-NKX6-2_MA0675.2 6 bp overlap

NOTO 1 dataset

Motif ES_0h ES_0h-NOTO_MA0710.2 7 bp overlap

NR2F1 1 dataset

Motif ES_0h ES_0h-NR2F1_MA1537.2 13 bp overlap

NR4A1 1 dataset

Motif ES_0h ES_0h-NR4A1_MA1112.3 8 bp overlap

Nr2f6 1 dataset

Motif ES_0h ES_0h-Nr2f6_MA0677.2 13 bp overlap

PAX3 1 dataset

Motif ES_0h ES_0h-PAX3_MA0780.1 10 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 128 bp overlap

PDX1 1 dataset

Motif ES_0h ES_0h-PDX1_MA0132.3 6 bp overlap

POLR2A 1 dataset

ChIP GM23338 ENCFF450WCS 129 bp overlap

POU1F1 1 dataset

Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap

POU2F1 1 dataset

Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 1 dataset

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 1 dataset

Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap

POU2F3 1 dataset

Motif ES_0h ES_0h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap

POU3F2 1 dataset

Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap

POU3F3 1 dataset

Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap

POU4F2 1 dataset

Motif ES_0h ES_0h-POU4F2_MA0683.2 15 bp overlap

POU5F1 14 datasets

Motif ES_0h ES_0h-POU5F1_MA1115.2 7 bp overlap

ChIP GM23338 ENCFF333SNB 264 bp overlap

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 453 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 406 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 463 bp overlap

ChIP WA01 ENCSR000BMU.POU5F1.WA01 292 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 283 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 303 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 206 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 263 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 415 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 322 bp overlap

ChIP hiPSC_3s2 GSE81899.POU5F1.hiPSC_3s2 281 bp overlap

POU5F1B 1 dataset

Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap

POU6F1 1 dataset

Motif ES_0h ES_0h-POU6F1_MA0628.2 6 bp overlap

POU6F2 1 dataset

Motif ES_0h ES_0h-POU6F2_MA0793.2 9 bp overlap

PRDM14 3 datasets

ChIP NCCIT GSE71675.PRDM14.NCCIT 226 bp overlap

ChIP hESC GSE22767.PRDM14.hESC 463 bp overlap

ChIP primordial-germ-cell-like-cell GSE138674.PRDM14.primordial-germ-cell-like-cell 242 bp overlap

PRRX1 1 dataset

Motif ES_0h ES_0h-PRRX1_MA0716.2 6 bp overlap

PRRX2 1 dataset

Motif ES_0h ES_0h-PRRX2_MA0075.4 7 bp overlap

Pax7 1 dataset

Motif ES_0h ES_0h-Pax7_MA0680.3 10 bp overlap

Pou5f1::Sox2 1 dataset

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

Pparg::Rxra 2 datasets

Motif DE_12h DE_12h-PpargRxra_MA0065.3 13 bp overlap

Motif ES_0h ES_0h-PpargRxra_MA0065.3 13 bp overlap

Prdm14 1 dataset

Motif ES_0h ES_0h-Prdm14_MA1998.2 8 bp overlap

RAX2 1 dataset

Motif ES_0h ES_0h-RAX2_MA0717.2 6 bp overlap

RNF2 2 datasets

ChIP WA01 GSE104690.RNF2.WA01 284 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 362 bp overlap

Rxra 1 dataset

Motif ES_0h ES_0h-Rxra_MA0512.2 14 bp overlap

SHOX 1 dataset

Motif ES_0h ES_0h-SHOX_MA0630.2 6 bp overlap

SMAD2_3 1 dataset

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 264 bp overlap

SMARCA4 2 datasets

ChIP hiPSC GSE124903.SMARCA4.hiPSC 306 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 318 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 213 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 381 bp overlap

SMARCC1 2 datasets

ChIP hiPSC GSE124903.SMARCC1.hiPSC 294 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 387 bp overlap

SOX2 2 datasets

ChIP hESC GSE18292.SOX2.hESC 198 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 336 bp overlap

SP1 1 dataset

ChIP WA01 ENCSR000BIR.SP1.WA01 282 bp overlap

SUZ12 4 datasets

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 134 bp overlap

ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 251 bp overlap

ChIP hiPSC GSE124903.SUZ12.hiPSC 79 bp overlap

ChIP hiPSC_WT GSE124903.SUZ12.hiPSC_WT 198 bp overlap

Shox2 1 dataset

Motif ES_0h ES_0h-Shox2_MA0720.2 6 bp overlap

TCF12 1 dataset

ChIP WA01 ENCSR000BIT.TCF12.WA01 203 bp overlap

TCF3 1 dataset

ChIP NPC GSE154479.TCF3.NPC 388 bp overlap

TCF7L1 1 dataset

Motif ES_0h ES_0h-TCF7L1_MA1421.1 12 bp overlap

TEAD1 1 dataset

Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap

TEAD3 1 dataset

Motif ES_0h ES_0h-TEAD3_MA0808.1 8 bp overlap

TEAD4 2 datasets

Motif ES_0h ES_0h-TEAD4_MA0809.3 8 bp overlap

ChIP H1 ENCFF778PAX 245 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 396 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_2d_TFAP2C_Induc 259 bp overlap

TLX2 1 dataset

Motif ES_0h ES_0h-TLX2_MA1577.2 6 bp overlap

TP53 1 dataset

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 223 bp overlap

UNCX 1 dataset

Motif ES_0h ES_0h-UNCX_MA0721.2 6 bp overlap

VAX1 1 dataset

Motif ES_0h ES_0h-VAX1_MA0722.2 7 bp overlap

VAX2 1 dataset

Motif ES_0h ES_0h-VAX2_MA0723.3 6 bp overlap

VSX1 1 dataset

Motif ES_0h ES_0h-VSX1_MA0725.2 7 bp overlap

VSX2 1 dataset

Motif ES_0h ES_0h-VSX2_MA0726.2 7 bp overlap

YY1 1 dataset

ChIP WA01 ENCSR000BKD.YY1.WA01 134 bp overlap

ZBTB12 2 datasets

Motif DE_12h DE_12h-ZBTB12_MA1649.2 7 bp overlap

Motif ES_0h ES_0h-ZBTB12_MA1649.2 7 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 318 bp overlap

ZNF320 2 datasets

Motif DE_12h DE_12h-ZNF320_MA1976.2 20 bp overlap

Motif ES_0h ES_0h-ZNF320_MA1976.2 20 bp overlap

ZNF335 1 dataset

ChIP HEK293 ENCSR328SUD.ZNF335.HEK293 295 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 423 bp overlap

mix-a 1 dataset

Motif ES_0h ES_0h-mix-a_MA0621.2 7 bp overlap