chr4 : 54,015,559 – 54,016,024
465 bp 97 TFs 1 linked gene
This 465 bp open chromatin element is linked to CHIC2 and is bound by 97 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
CHIC2 48.8 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr4:54,010,559 – 54,021,024
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
97 transcription factors
Source
Cell type
AR 2 datasets
ChIP VCaP_R1881_30M GSE84432.AR.VCaP_R1881_30M 257 bp overlap
ChIP VCaP_R1881_4H GSE84432.AR.VCaP_R1881_4H 279 bp overlap
ARID1A 1 dataset
ChIP HAP1 GSE108387.ARID1A.HAP1 465 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 435 bp overlap
ASXL3 1 dataset
ChIP NCI-H1963_Ab1 GSE145028.ASXL3.NCI-H1963_Ab1 206 bp overlap
ATF2 1 dataset
ChIP WA01 ENCSR000BQU.ATF2.WA01 134 bp overlap
ATF4 1 dataset
Motif ES_0h ES_0h-ATF4_MA0833.3 10 bp overlap
Arid3a 1 dataset
Motif ES_0h ES_0h-Arid3a_MA0151.1 6 bp overlap
BCOR 4 datasets
ChIP WA01 GSE104690.BCOR.WA01 465 bp overlap
ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 298 bp overlap
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 186 bp overlap
ChIP WA01_RNF2-R_Doxycyclin GSE104690.BCOR.WA01_RNF2-R_Doxycyclin 465 bp overlap
BRD4 7 datasets
ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 465 bp overlap
ChIP HAP1 GSE108387.BRD4.HAP1 465 bp overlap
ChIP NCI-H1963_shASXL3 GSE145028.BRD4.NCI-H1963_shASXL3 394 bp overlap
ChIP NCI-H1963_shNONT GSE145028.BRD4.NCI-H1963_shNONT 177 bp overlap
ChIP cortical-interneuron_KCl-pos GSE117508.BRD4.cortical-interneuron_KCl-pos 60 bp overlap
ChIP cortical-interneuron_R133C_KCl-neg_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-neg_JQ1-neg 137 bp overlap
ChIP cortical-interneuron_R133C_KCl-pos_JQ1-neg GSE117508.BRD4.cortical-interneuron_R133C_KCl-pos_JQ1-neg 373 bp overlap
CBX7 1 dataset
ChIP hESC_QKO GSE133412.CBX7.hESC_QKO 297 bp overlap
CEBPG 1 dataset
Motif ES_0h ES_0h-CEBPG_MA1636.2 10 bp overlap
CHD7 2 datasets
ChIP WA01 ENCSR000AVA.CHD7.WA01 363 bp overlap
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 465 bp overlap
CREB1 1 dataset
ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 133 bp overlap
CTCF 1 dataset
ChIP HAP1_clone21_CTCF-CRISPR GSE152721.CTCF.HAP1_clone21_CTCF-CRISPR 432 bp overlap
CTNNB1 1 dataset
ChIP hESC_activinA_15h GSE99202.CTNNB1.hESC_activinA_15h 377 bp overlap
EP300 1 dataset
ChIP hESC GSE17917.EP300.hESC 392 bp overlap
ERG 1 dataset
ChIP VCaP GSE49091.ERG.VCaP 162 bp overlap
ESR1 1 dataset
Motif DE_12h DE_12h-ESR1_MA0112.4 15 bp overlap
FOXG1 1 dataset
Motif ES_0h ES_0h-FOXG1_MA0613.1 8 bp overlap
FOXN3 1 dataset
Motif ES_0h ES_0h-FOXN3_MA1489.1 8 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 213 bp overlap
GATA3 1 dataset
ChIP Kelly GSE65664.GATA3.Kelly 153 bp overlap
GATA4 1 dataset
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 223 bp overlap
HAND2 4 datasets
ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 465 bp overlap
Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap
ChIP Kelly GSE94822.HAND2.Kelly 196 bp overlap
ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 250 bp overlap
HDAC2 2 datasets
ChIP H1 ENCFF353UJQ 465 bp overlap
ChIP H1 ENCFF939VKA 232 bp overlap
HOXB13 1 dataset
ChIP G-401 GSE65381.HOXB13.G-401 124 bp overlap
HSF1 1 dataset
ChIP MO91 GSE45852.HSF1.MO91 176 bp overlap
Hmga1 1 dataset
Motif ES_0h ES_0h-Hmga1_MA2124.1 8 bp overlap
Irf1 1 dataset
Motif ES_0h ES_0h-Irf1_MA0050.4 11 bp overlap
JUN 3 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 303 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 275 bp overlap
ChIP HUES-8 GSE109524.JUN.HUES-8 279 bp overlap
JUND 1 dataset
ChIP liver ENCSR196HGZ.JUND.liver 219 bp overlap
KLF4 2 datasets
ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 113 bp overlap
ChIP HAP1 GSE130417.KLF4.HAP1 456 bp overlap
LIN54 1 dataset
Motif DE_12h DE_12h-LIN54_MA0619.2 7 bp overlap
MAFK 1 dataset
ChIP OCI-Ly7 GSE47784.MAFK.OCI-Ly7 145 bp overlap
MAX 1 dataset
ChIP WA01 ENCSR000EUP.MAX.WA01 212 bp overlap
MEIS1 2 datasets
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
MEIS2 1 dataset
Motif DE_12h DE_12h-MEIS2_MA0774.1 8 bp overlap
MEIS3 1 dataset
Motif DE_12h DE_12h-MEIS3_MA0775.2 7 bp overlap
MORC2 1 dataset
ChIP H9 GSE95374.MORC2.H9 228 bp overlap
MYC 1 dataset
ChIP CD34 GSE85488.MYC.CD34 205 bp overlap
NANOG 11 datasets
ChIP GM23338 ENCFF065NZG 311 bp overlap
ChIP GM23338 ENCSR061DGF.NANOG.GM23338 302 bp overlap
ChIP H1 ENCFF747ZPQ 241 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 465 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 465 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 267 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 465 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 465 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 465 bp overlap
ChIP hESC GSE20650.NANOG.hESC 465 bp overlap
ChIP hESC GSE18292.NANOG.hESC 379 bp overlap
NIPBL 2 datasets
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 300 bp overlap
ChIP hESC_activin GSE64758.NIPBL.hESC_activin 210 bp overlap
NR1H4::RXRA 1 dataset
Motif DE_12h DE_12h-NR1H4RXRA_MA1146.2 13 bp overlap
NR1I3 1 dataset
Motif ES_0h ES_0h-NR1I3_MA1534.2 8 bp overlap
NR2F1 1 dataset
Motif DE_12h DE_12h-NR2F1_MA1538.1 15 bp overlap
NR2F6 1 dataset
Motif DE_12h DE_12h-NR2F6_MA1539.1 15 bp overlap
NR6A1 1 dataset
Motif ES_0h ES_0h-NR6A1_MA1541.2 14 bp overlap
Nr5A2 1 dataset
Motif DE_12h DE_12h-Nr5A2_MA0505.3 9 bp overlap
ONECUT1 2 datasets
ChIP H9 ERP004206.ONECUT1.H9 309 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.ONECUT1.pancreatic-progenitor_PP1 465 bp overlap
PAX7 1 dataset
ChIP H9_DOX GSE98976.PAX7.H9_DOX 159 bp overlap
PCGF1 1 dataset
ChIP WA01 GSE104690.PCGF1.WA01 298 bp overlap
PDX1 2 datasets
ChIP hiPSC GSE125768.PDX1.hiPSC 326 bp overlap
ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 225 bp overlap
PHOX2B 1 dataset
ChIP CLB-Ga GSE90683.PHOX2B.CLB-Ga 164 bp overlap
POU1F1 1 dataset
Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap
POU2F1 1 dataset
Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap
POU2F1::SOX2 2 datasets
Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap
POU2F2 1 dataset
Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap
POU2F3 1 dataset
Motif ES_0h ES_0h-POU2F3_MA0627.3 9 bp overlap
POU3F1 1 dataset
Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap
POU3F2 3 datasets
Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap
ChIP hiPSC_SGC0946 GSE149017.POU3F2.hiPSC_SGC0946 194 bp overlap
ChIP hiPSC_SGC0946 GSE149017.POU3F2.hiPSC_SGC0946 188 bp overlap
POU3F3 1 dataset
Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap
POU3F4 1 dataset
Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap
POU4F2 2 datasets
ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 156 bp overlap
ChIP HNPC_DIF GSE74814.POU4F2.HNPC_DIF 156 bp overlap
POU5F1 12 datasets
ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 139 bp overlap
Motif ES_0h ES_0h-POU5F1_MA1115.2 7 bp overlap
ChIP GM23338 ENCFF333SNB 311 bp overlap
ChIP HUES-8 GSE109524.POU5F1.HUES-8 465 bp overlap
ChIP NCCIT GSE36134.POU5F1.NCCIT 312 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 465 bp overlap
ChIP WA09 GSE105028.POU5F1.WA09 403 bp overlap
ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 323 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 377 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 465 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 465 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 271 bp overlap
POU5F1B 1 dataset
Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap
Pou5f1::Sox2 1 dataset
Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap
RAD21 4 datasets
ChIP HAP1 GSE152721.RAD21.HAP1 465 bp overlap
ChIP HAP1 GSE126634.RAD21.HAP1 283 bp overlap
ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 422 bp overlap
ChIP HAP1_clone25 GSE152721.RAD21.HAP1_clone25 465 bp overlap
RBBP5 1 dataset
ChIP WA01 ENCSR000AQC.RBBP5.WA01 150 bp overlap
RBPJ 1 dataset
ChIP GSC8-11_dasatinib GSE74557.RBPJ.GSC8-11_dasatinib 462 bp overlap
RFX1 1 dataset
Motif DE_12h DE_12h-RFX1_MA0509.3 16 bp overlap
RFX3 1 dataset
Motif DE_12h DE_12h-RFX3_MA0798.3 16 bp overlap
SIN3A 6 datasets
ChIP H1 ENCFF042ZSL 392 bp overlap
ChIP H1 ENCFF896IJG 301 bp overlap
ChIP WA01 ENCSR000BIS.SIN3A.WA01 197 bp overlap
ChIP WA01 ENCSR000EBO.SIN3A.WA01 210 bp overlap
ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 232 bp overlap
ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 172 bp overlap
SMAD1 1 dataset
ChIP BG03 GSE36578.SMAD1.BG03 96 bp overlap
SMAD2 1 dataset
ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 330 bp overlap
SMAD3 1 dataset
ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 162 bp overlap
SMARCA4 6 datasets
ChIP NPC_siCT GSE122631.SMARCA4.NPC_siCT 465 bp overlap
ChIP NPC_siSOX GSE122631.SMARCA4.NPC_siSOX 385 bp overlap
ChIP NSC GSE125033.SMARCA4.NSC 465 bp overlap
ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 465 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 465 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 465 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 238 bp overlap
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 465 bp overlap
SMARCC1 2 datasets
ChIP hiPSC GSE124903.SMARCC1.hiPSC 465 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 465 bp overlap
SOX2 10 datasets
ChIP H9 GSE46837.SOX2.H9 254 bp overlap
ChIP HNSC GSE69479.SOX2.HNSC 465 bp overlap
ChIP NPC GSE122631.SOX2.NPC 431 bp overlap
ChIP RENVM GSE49404.SOX2.RENVM 217 bp overlap
ChIP hESC GSE18292.SOX2.hESC 305 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 465 bp overlap
ChIP hiPSC GSE67282.SOX2.hiPSC 443 bp overlap
ChIP hiPSC_INHI GSE67282.SOX2.hiPSC_INHI 216 bp overlap
ChIP hiPSC_KDP53 GSE67282.SOX2.hiPSC_KDP53 465 bp overlap
ChIP hiPSC_KDP53_INHI GSE67282.SOX2.hiPSC_KDP53_INHI 465 bp overlap
SOX9 1 dataset
Motif DE_12h DE_12h-SOX9_MA0077.2 8 bp overlap
SP1 1 dataset
ChIP WA01 ENCSR000BIR.SP1.WA01 231 bp overlap
Six4 1 dataset
Motif ES_0h ES_0h-Six4_MA2001.2 7 bp overlap
TCF3 1 dataset
ChIP NPC GSE154479.TCF3.NPC 405 bp overlap
TEAD1 2 datasets
Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap
ChIP WTC11 ENCFF502QUV 363 bp overlap
TEAD4 1 dataset
Motif ES_0h ES_0h-TEAD4_MA0809.3 8 bp overlap
TGIF1 1 dataset
Motif DE_12h DE_12h-TGIF1_MA0796.1 12 bp overlap
TP53 2 datasets
ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 465 bp overlap
ChIP hESC_DIFF GSE39912.TP53.hESC_DIFF 364 bp overlap
YY1 2 datasets
ChIP H1 ENCFF524BTL 308 bp overlap
ChIP WA01 ENCSR000BKD.YY1.WA01 154 bp overlap
Yy1 1 dataset
Motif DE_12h DE_12h-Yy1_MA0095.4 8 bp overlap
ZIC1 1 dataset
Motif DE_12h DE_12h-ZIC1_MA0696.1 14 bp overlap
ZIC4 1 dataset
Motif DE_12h DE_12h-ZIC4_MA0751.2 14 bp overlap
ZIC5 1 dataset
Motif DE_12h DE_12h-ZIC5_MA1584.2 15 bp overlap
ZNF283 1 dataset
ChIP HEK293T GSE78099.ZNF283.HEK293T 157 bp overlap
ZNF462 2 datasets
ChIP GM23338 ENCFF896CCA 251 bp overlap
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 224 bp overlap
ZNF667 1 dataset
Motif DE_12h DE_12h-ZNF667_MA1984.2 11 bp overlap
ZNF669 1 dataset
Motif DE_12h DE_12h-ZNF669_MA1985.1 15 bp overlap
Zfp335 2 datasets
Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap
Motif DE_12h DE_12h-Zfp335_MA2002.2 7 bp overlap
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