chr2:27,681,105–27,682,049

chr2 : 27,681,105 – 27,682,049

944 bp 85 TFs 11 linked genes

This 944 bp open chromatin element is linked to 11 target genes and is bound by 85 transcription factors.

Linked Genes

11 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SLC4A1AP		17.7 kb	Distal	Multiome
SUPT7L		18.0 kb	Distal	Multiome
GPN1		52.6 kb	Distal	Multiome
MRPL33		90.1 kb	Distal	Multiome
ZNF512		98.6 kb	Distal	Multiome
IFT172		191.9 kb	Distal	Multiome
RBKS		208.7 kb	Distal	Multiome
BABAM2		209.2 kb	Distal	Multiome
KRTCAP3		239.3 kb	Distal	Multiome
NRBP1		253.0 kb	Distal	Multiome
PPM1G		272.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

85 transcription factors

ChIP 22Rv1 GSE85558.AR.22Rv1 237 bp overlap

ChIP THP-1_R1881 GSE131381.AR.THP-1_R1881 214 bp overlap

ARID1A 5 datasets

ChIP 12Z GSE129781.ARID1A.12Z 191 bp overlap

ChIP RMG-I GSE104545.ARID1A.RMG-I 944 bp overlap

ChIP RMG-I GSE120058.ARID1A.RMG-I 59 bp overlap

ChIP endometrial-epithelial-cells GSE106660.ARID1A.endometrial-epithelial-cells 140 bp overlap

ChIP endometrial-epithelial-cells_KO GSE106660.ARID1A.endometrial-epithelial-cells_KO 73 bp overlap

ARNTL 1 dataset

ChIP U2OS_DMOG GSE85096.ARNTL.U2OS_DMOG 230 bp overlap

ChIP HCT-116_CAMP GSE74355.ATF3.HCT-116_CAMP 116 bp overlap

BHLHE40 1 dataset

ChIP IMR-90 ENCSR957KYB.BHLHE40.IMR-90 121 bp overlap

BRD2 2 datasets

ChIP SK-MEL-147 GSE94488.BRD2.SK-MEL-147 242 bp overlap

ChIP SK-MEL-147_JQ1 GSE94488.BRD2.SK-MEL-147_JQ1 125 bp overlap

BRD3 2 datasets

ChIP H-1_DE GSE126661.BRD3.H-1_DE 151 bp overlap

ChIP H-1_DE GSE126661.BRD3.H-1_DE 295 bp overlap

BRD4 11 datasets

ChIP CD4_JG1 GSE33281.BRD4.CD4_JG1 249 bp overlap

ChIP HCC1395 GSE63581.BRD4.HCC1395 224 bp overlap

ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 145 bp overlap

ChIP SUM159PT_100nMtrametinib_1h GSE87418.BRD4.SUM159PT_100nMtrametinib_1h 119 bp overlap

ChIP SUM159PT_100nMtrametinib_24h GSE87418.BRD4.SUM159PT_100nMtrametinib_24h 246 bp overlap

ChIP SUM159PT_100nMtrametinib_4h GSE87418.BRD4.SUM159PT_100nMtrametinib_4h 262 bp overlap

ChIP SUM159PT_100nMtrametinib_72h GSE87418.BRD4.SUM159PT_100nMtrametinib_72h 227 bp overlap

ChIP SUM159PT_100nMtrametinib_8h GSE87418.BRD4.SUM159PT_100nMtrametinib_8h 69 bp overlap

ChIP SUM159PT_30nMbortezomib_8h GSE87418.BRD4.SUM159PT_30nMbortezomib_8h 244 bp overlap

ChIP SUM159PT_DMSO_8h GSE87418.BRD4.SUM159PT_DMSO_8h 64 bp overlap

ChIP SUM159PT_shMYC_DMSO_48h GSE87418.BRD4.SUM159PT_shMYC_DMSO_48h 53 bp overlap

CBFA2T3 1 dataset

ChIP K562 ENCFF673OEZ 196 bp overlap

CDX2 2 datasets

ChIP LS180_125 GSE31939.CDX2.LS180_125 135 bp overlap

ChIP adult-duodenal-cell GSE115314.CDX2.adult-duodenal-cell 216 bp overlap

CREBBP 2 datasets

ChIP PC-3 GSE147455.CREBBP.PC-3 173 bp overlap

ChIP PC-3_GDC-resist GSE147455.CREBBP.PC-3_GDC-resist 157 bp overlap

ChIP U2OS_cordycepin GSE130506.CRY1.U2OS_cordycepin 255 bp overlap

EHMT2 1 dataset

ChIP K-562 ENCSR175EOM.EHMT2.K-562 99 bp overlap

ELF3 2 datasets

ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 81 bp overlap

ChIP PDAC_SHCTR GSE64557.ELF3.PDAC_SHCTR 158 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 533 bp overlap

EP300 2 datasets

ChIP PC-3 GSE147455.EP300.PC-3 182 bp overlap

ChIP PC-3 GSE147455.EP300.PC-3 193 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 215 bp overlap

ChIP CFPAC-1 GSE119930.FOS.CFPAC-1 300 bp overlap

FOSL2 1 dataset

ChIP NPC_R1159Q GSE122631.FOSL2.NPC_R1159Q 125 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 758 bp overlap

ChIP DE DE-FOXA2-2 802 bp overlap

FOXP4 1 dataset

ChIP K562 ENCFF086EQT 88 bp overlap

GATA1 1 dataset

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 67 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 934 bp overlap

ChIP DE DE-GATA4-2 944 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 925 bp overlap

ChIP DE DE-GATA6-2 944 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 470 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 610 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 552 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 944 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 301 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 569 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 636 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 875 bp overlap

HDAC2 1 dataset

ChIP PC-3 GSE147455.HDAC2.PC-3 204 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 70 bp overlap

HINFP 1 dataset

ChIP K-562 ENCSR619GFP.HINFP.K-562 486 bp overlap

HMGB2 1 dataset

ChIP IMR-90_proliferating GSE98245.HMGB2.IMR-90_proliferating 292 bp overlap

HNF4A 12 datasets

ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 252 bp overlap

ChIP Caco-2_PROLIF GSE23436.HNF4A.Caco-2_PROLIF 124 bp overlap

ChIP GP5D GSE51234.HNF4A.GP5D 627 bp overlap

ChIP GP5D_SIRAD21 GSE51234.HNF4A.GP5D_SIRAD21 279 bp overlap

ChIP HCT-116 GSE62890.HNF4A.HCT-116 166 bp overlap

ChIP IM95 GSE114018.HNF4A.IM95 237 bp overlap

ChIP KATO-III GSE114018.HNF4A.KATO-III 344 bp overlap

ChIP LoVo_PHASES GSE51290.HNF4A.LoVo_PHASES 276 bp overlap

ChIP gastric-epithelial-cell_OE GSE114018.HNF4A.gastric-epithelial-cell_OE 346 bp overlap

ChIP liver ENCFF354NRH 288 bp overlap

ChIP liver ENCFF449HPV 301 bp overlap

ChIP liver ERP002306.HNF4A.liver 123 bp overlap

IKZF1 2 datasets

ChIP K-562 ENCSR395HWC.IKZF1.K-562 117 bp overlap

ChIP K562 ENCFF348IBL 163 bp overlap

ChIP T-cell GSE136853.IRF4.T-cell 271 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 386 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 508 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 465 bp overlap

JUNB 2 datasets

ChIP CFPAC-1 GSE119930.JUNB.CFPAC-1 399 bp overlap

ChIP Karpas-299 GSE151413.JUNB.Karpas-299 221 bp overlap

ChIP HCT-116 ENCSR000BSH.MAX.HCT-116 132 bp overlap

ChIP HCT116 ENCFF810LEN 275 bp overlap

ChIP HeLa-S3 ENCSR000EZF.MAX.HeLa-S3 107 bp overlap

MED1 4 datasets

ChIP HCT-116 GSE121798.MED1.HCT-116 793 bp overlap

ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 264 bp overlap

ChIP HCT-116_thaps GSE121798.MED1.HCT-116_thaps 319 bp overlap

ChIP SUM159PT_DMSO_24h GSE87418.MED1.SUM159PT_DMSO_24h 72 bp overlap

ChIP A-549_MGA-OE GSE112188.MGA.A-549_MGA-OE 189 bp overlap

ChIP A-549_empty GSE112188.MGA.A-549_empty 225 bp overlap

MLLT1 1 dataset

ChIP K-562 ENCSR107GRP.MLLT1.K-562 50 bp overlap

ChIP K-562 ENCSR113LAS.MTA2.K-562 170 bp overlap

ChIP LS174T_BI8622 GSE59223.MYC.LS174T_BI8622 110 bp overlap

ChIP SHEP-21N GSE80151.MYCN.SHEP-21N 64 bp overlap

MYOD1 1 dataset

ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 270 bp overlap

NCAPH2 1 dataset

ChIP RMG-I GSE120058.NCAPH2.RMG-I 944 bp overlap

NR1H2 1 dataset

ChIP HT29_GW3965_48H GSE77039.NR1H2.HT29_GW3965_48H 182 bp overlap

NR3C1 1 dataset

ChIP BEAS-2B_TNF_IA1 GSE125623.NR3C1.BEAS-2B_TNF_IA1 114 bp overlap

ONECUT1 1 dataset

ChIP liver ERP002306.ONECUT1.liver 130 bp overlap

ONECUT2 1 dataset

ChIP A-549 GSE102599.ONECUT2.A-549 226 bp overlap

ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 93 bp overlap

POLR2A 3 datasets

ChIP body of pancreas ENCFF675RCN 436 bp overlap

ChIP body of pancreas ENCFF727UBE 204 bp overlap

ChIP transverse colon ENCFF610RWV 280 bp overlap

POU5F1 1 dataset

ChIP BJ_INDUCED GSE36570.POU5F1.BJ_INDUCED 143 bp overlap

PPARG 2 datasets

ChIP HT29_ROSIG_2H GSE77039.PPARG.HT29_ROSIG_2H 202 bp overlap

ChIP HT29_ROSIG_48H GSE77039.PPARG.HT29_ROSIG_48H 212 bp overlap

PRDM10 1 dataset

ChIP Hep-G2 ENCSR289PSX.PRDM10.Hep-G2 172 bp overlap

PROX1 1 dataset

ChIP SW480 GSE60390.PROX1.SW480 162 bp overlap

RAD21 1 dataset

ChIP SLK_CTCF-KD GSE138105.RAD21.SLK_CTCF-KD 184 bp overlap

ChIP aortic-endothelial-cell_IL1B_D41 GSE139377.RELA.aortic-endothelial-cell_IL1B_D41 213 bp overlap

ChIP macrophage ERP008801.RXR.macrophage 104 bp overlap

ChIP JMSU-1 GSE107734.RXRA.JMSU-1 175 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 290 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 944 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 681 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 613 bp overlap

SMAD2_3 5 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 563 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 651 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 432 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 944 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 944 bp overlap

SMAD3 3 datasets

ChIP HCC1954 GSE104760.SMAD3.HCC1954 137 bp overlap

ChIP HCC1954_TGFb GSE104760.SMAD3.HCC1954_TGFb 135 bp overlap

ChIP endoderm GSE29422.SMAD3.endoderm 244 bp overlap

SMAD4 1 dataset

ChIP endoderm GSE29422.SMAD4.endoderm 264 bp overlap

SMARCA2 2 datasets

ChIP NPC_K755R-siCT GSE122631.SMARCA2.NPC_K755R-siCT 228 bp overlap

ChIP NPC_R1159Q_AM GSE122631.SMARCA2.NPC_R1159Q_AM 374 bp overlap

SMARCA4 10 datasets

ChIP A-549_AG15678 GSE132290.SMARCA4.A-549_AG15678 85 bp overlap

ChIP A-549_AG15686 GSE132290.SMARCA4.A-549_AG15686 395 bp overlap

ChIP A-549_AG15687 GSE132290.SMARCA4.A-549_AG15687 211 bp overlap

ChIP A-549_AG15688 GSE132290.SMARCA4.A-549_AG15688 236 bp overlap

ChIP A-549_AG15725 GSE132290.SMARCA4.A-549_AG15725 86 bp overlap

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4 296 bp overlap

ChIP NPC_K755R-siAP GSE122631.SMARCA4.NPC_K755R-siAP 248 bp overlap

ChIP NPC_K755R-siCT GSE122631.SMARCA4.NPC_K755R-siCT 274 bp overlap

ChIP TTC-1240_R377H GSE124903.SMARCA4.TTC-1240_R377H 240 bp overlap

ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 418 bp overlap

SMARCB1 1 dataset

ChIP proliferating-human-fibroblast GSE131711.SMARCB1.proliferating-human-fibroblast 64 bp overlap

SMARCC1 2 datasets

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCC1.BIN-67_lentivirus-SMARCA4-T910M 286 bp overlap

ChIP TTC-549_Dox GSE71504.SMARCC1.TTC-549_Dox 150 bp overlap

SNAI2 2 datasets

ChIP PC-9_2DF GSE131687.SNAI2.PC-9_2DF 482 bp overlap

ChIP SMS-CTR_shSNAI2 GSE137168.SNAI2.SMS-CTR_shSNAI2 382 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 445 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 846 bp overlap

SOX2 2 datasets

ChIP HNSC GSE69479.SOX2.HNSC 129 bp overlap

ChIP OSKM GSE81899.SOX2.OSKM 65 bp overlap

SPI1 2 datasets

ChIP DC_96h_donorM GSE128834.SPI1.DC_96h_donorM 292 bp overlap

ChIP primary-monocyte_4h_donorO GSE128834.SPI1.primary-monocyte_4h_donorO 145 bp overlap

STAT1 1 dataset

ChIP CD14_LPS GSE43036.STAT1.CD14_LPS 122 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 221 bp overlap

TAL1 6 datasets

ChIP CHRF28811 ERP008568.TAL1.CHRF28811 163 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 130 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 89 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 143 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 166 bp overlap

ChIP erythroid GSE42390.TAL1.erythroid 143 bp overlap

TCF12 2 datasets

ChIP K-562 ENCSR744WOO.TCF12.K-562 123 bp overlap

ChIP K562 ENCFF931DJY 183 bp overlap

ChIP K-562 ENCSR970OJY.TCF3.K-562 101 bp overlap

TERF1 1 dataset

ChIP LCL GSE55053.TERF1.LCL 135 bp overlap

ZBTB17 1 dataset

ChIP HEK293 ENCFF865LIO 131 bp overlap

ZBTB20 2 datasets

ChIP HEK293 ENCFF524ADK 617 bp overlap

ChIP HEK293 ENCSR460MBI.ZBTB20.HEK293 328 bp overlap

ZFP64 1 dataset

ChIP HEK293 GSE76494.ZFP64.HEK293 200 bp overlap

ZNF362 1 dataset

ChIP HEK293 ENCSR715QNO.ZNF362.HEK293 365 bp overlap

ZNF394 2 datasets

ChIP HEK293 ENCFF236OPX 208 bp overlap

ChIP HEK293 ENCSR125DNC.ZNF394.HEK293 134 bp overlap

ZNF512 1 dataset

ChIP K562 ENCFF601EMZ 199 bp overlap

ZNF608 1 dataset

ChIP SK-N-SH ENCFF518LYG 247 bp overlap

ZNF629 1 dataset

ChIP HEK293 ENCSR351NON.ZNF629.HEK293 206 bp overlap

ZNF692 1 dataset

ChIP HEK293 ENCSR418MKG.ZNF692.HEK293 160 bp overlap