Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025]
Transcription factors with Perturb-seq knockdown data for KRTCAP3. The Binding column indicates whether any binding evidence exists for this TF–gene pair (ChIP-seq or motif footprint peaks). The Mean coef is the average Perturb-seq regression coefficient across active gRNAs (positive = KRTCAP3 upregulated upon KD; negative = downregulated). The Outlier column indicates whether this gene is in the top or bottom 5% of all TF knockdown effects.
| TF | Mean coef | Binding | Outlier | TF→Gene link |
|---|
Open chromatin peaks (ATAC-seq) in the genomic neighbourhood of KRTCAP3, linked by TSS proximity or chromatin conformation (Multiome / HiCAR). Each element overlaps at least one TF ChIP-seq binding site — the TFs column shows how many distinct TFs bind that element.
| Accessibility | Element | Dist. to TSS | Link type | TFs |
|---|---|---|---|---|
| chr2:27,211,255–27,212,840 | 230.2 kb | Distal (>10kb) Multiome | 978 | |
| chr2:27,217,045–27,218,005 | 225.0 kb | Distal (>10kb) Multiome | 771 | |
| chr2:27,250,040–27,250,883 | 192.0 kb | Distal (>10kb) Multiome | 559 | |
| chr2:27,262,260–27,263,337 | 179.4 kb | Distal (>10kb) Multiome | 376 | |
| chr2:27,264,406–27,265,326 | 177.2 kb | Distal (>10kb) Multiome | 696 | |
| chr2:27,306,488–27,307,261 | 135.7 kb | Distal (>10kb) Multiome | 115 | |
| chr2:27,322,773–27,323,423 | 119.3 kb | Distal (>10kb) Multiome | 906 | |
| chr2:27,356,094–27,357,596 | 85.4 kb | Distal (>10kb) Multiome | 1084 | |
| chr2:27,369,685–27,371,261 | 72.0 kb | Distal (>10kb) Multiome | 1096 | |
| chr2:27,380,026–27,381,202 | 61.6 kb | Distal (>10kb) Multiome | 821 | |
| chr2:27,408,972–27,410,056 | 32.7 kb | Distal (>10kb) Multiome | 989 | |
| chr2:27,428,202–27,429,633 | 13.7 kb | Distal (>10kb) Multiome | 1013 | |
| chr2:27,441,811–27,442,884 | 27 bp | At TSS Multiome | 380 | |
| chr2:27,489,334–27,490,205 | 47.5 kb | Distal (>10kb) Multiome | 731 | |
| chr2:27,494,797–27,495,577 | 52.8 kb | Distal (>10kb) Multiome | 380 | |
| chr2:27,517,085–27,517,958 | 75.2 kb | Distal (>10kb) Multiome | 130 | |
| chr2:27,582,572–27,583,317 | 140.6 kb | Distal (>10kb) Multiome | 843 | |
| chr2:27,628,534–27,629,380 | 186.6 kb | Distal (>10kb) Multiome | 828 | |
| chr2:27,663,338–27,664,216 | 221.4 kb | Distal (>10kb) Multiome | 1035 | |
| chr2:27,681,105–27,682,049 | 239.3 kb | Distal (>10kb) Multiome | 85 | |
| chr2:27,715,293–27,715,981 | 273.6 kb | Distal (>10kb) Multiome | 346 | |
| chr2:27,735,279–27,736,049 | 293.2 kb | Distal (>10kb) Multiome | 395 |
Genomic view of the KRTCAP3 locus showing ATAC-seq accessibility and RNA-seq expression across the ESC → DE time course, together with TF binding peaks and element-to-TSS loop connections.