chr19:14,247,378–14,248,008

chr19 : 14,247,378 – 14,248,008

630 bp 109 TFs 16 linked genes

This 630 bp open chromatin element is linked to 16 target genes and is bound by 109 transcription factors.

Linked Genes

16 genes

Gene	Expression	Dist. to TSS	Distance	Link type
ENSG00000267723		45.6 kb	Distal	Multiome
ADGRL1		86.1 kb	Distal	Multiome
ADGRL1-AS1		110.4 kb	Distal	Multiome
ASF1B		111.0 kb	Distal	Multiome
LINC01841		116.4 kb	Distal	Multiome
PRKACA		129.8 kb	Distal	Multiome
SAMD1		156.9 kb	Distal	Multiome
DDX39A		171.7 kb	Distal	Multiome
PKN1		185.9 kb	Distal	Multiome
PALM3		190.0 kb	Distal	Multiome
IL27RA		215.9 kb	Distal	Multiome
RFX1		241.3 kb	Distal	Multiome
GIPC1		248.5 kb	Distal	Multiome
DNAJB1		281.7 kb	Distal	Multiome
TECR		282.0 kb	Distal	Multiome
DCAF15		295.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

109 transcription factors

ChIP K562 ENCFF343XWA 87 bp overlap

BHLHE22 1 dataset

Motif DE_24h DE_24h-BHLHE22_MA1635.2 6 bp overlap

ChIP HAP1 GSE108387.BRD4.HAP1 215 bp overlap

ChIP HCT-116_NOMO GSE38258.CDK8.HCT-116_NOMO 206 bp overlap

CTCFL 1 dataset

Motif DE_24h DE_24h-CTCFL_MA1102.3 8 bp overlap

ChIP WTC11 ENCFF449LLF 428 bp overlap

ChIP GM12878 ENCFF266FYW 203 bp overlap

ERF::FIGLA 1 dataset

Motif DE_24h DE_24h-ERFFIGLA_MA1934.2 13 bp overlap

ETV2::HOXB13 1 dataset

Motif DE_24h DE_24h-ETV2HOXB13_MA1943.2 13 bp overlap

ETV5::FIGLA 1 dataset

Motif DE_24h DE_24h-ETV5FIGLA_MA1945.2 14 bp overlap

EZH2 3 datasets

ChIP GM23248 ENCFF404ZHM 300 bp overlap

ChIP neural progenitor cell ENCFF018MKA 630 bp overlap

ChIP neural progenitor cell ENCFF018MKA 527 bp overlap

FIGLA 2 datasets

Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap

Motif DE_24h DE_24h-FIGLA_MA0820.2 6 bp overlap

ChIP SKNO-1 GSE23730.FLI1.SKNO-1 120 bp overlap

GATA6 3 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 421 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 314 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 604 bp overlap

GLIS2 1 dataset

Motif DE_24h DE_24h-GLIS2_MA0736.1 14 bp overlap

GTF2I 3 datasets

ChIP K562 ENCFF539BYI 208 bp overlap

ChIP WTC11 ENCFF255XXZ 177 bp overlap

ChIP WTC11 ENCFF255XXZ 91 bp overlap

HDAC2 1 dataset

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP HEK293 ENCFF252CFL 187 bp overlap

IKZF1 3 datasets

ChIP GM12878 ENCFF753XDO 426 bp overlap

ChIP K562 ENCFF348IBL 142 bp overlap

ChIP pre-B-cell GSE107886.IKZF1.pre-B-cell 131 bp overlap

IKZF3 1 dataset

ChIP HEK293 ENCFF518OXG 104 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 503 bp overlap

ChIP DE_D1 S13-DE-d1-JUN-exp1 294 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 609 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 606 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 630 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 617 bp overlap

KDM1A 5 datasets

ChIP H1 ENCFF696SGD 458 bp overlap

ChIP H1 ENCFF696SGD 93 bp overlap

ChIP K562 ENCFF128TYE 198 bp overlap

ChIP K562 ENCFF133OLU 218 bp overlap

ChIP K562 ENCFF934ZRG 214 bp overlap

ChIP H1 ENCFF914VQY 306 bp overlap

Motif DE_24h DE_24h-MAZ_MA1522.2 8 bp overlap

MED26 1 dataset

ChIP HCT-116_aux GSE121355.MED26.HCT-116_aux 299 bp overlap

MEF2A 1 dataset

Motif DE_24h DE_24h-MEF2A_MA0052.5 10 bp overlap

MEF2C 1 dataset

Motif DE_24h DE_24h-MEF2C_MA0497.2 11 bp overlap

MIER1 1 dataset

ChIP K562 ENCFF584AYC 454 bp overlap

MLLT1 3 datasets

ChIP GM12878 ENCFF995GXC 280 bp overlap

ChIP GM12878 ENCFF995GXC 280 bp overlap

ChIP K562 ENCFF074XRJ 262 bp overlap

Motif DE_24h DE_24h-MZF1_MA0056.3 8 bp overlap

NANOG 1 dataset

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP GM12878 ENCFF213ZNN 342 bp overlap

NFATC3 1 dataset

Motif DE_24h DE_24h-NFATC3_MA0625.3 6 bp overlap

Motif DE_24h DE_24h-NFIA_MA0670.2 6 bp overlap

Motif DE_24h DE_24h-NFIB_MA1643.2 17 bp overlap

Motif DE_24h DE_24h-NFIC_MA1527.2 15 bp overlap

NFIC::TLX1 1 dataset

Motif DE_24h DE_24h-NFICTLX1_MA0119.1 14 bp overlap

NFIX 2 datasets

Motif DE_24h DE_24h-NFIX_MA0671.2 6 bp overlap

Motif DE_24h DE_24h-NFIX_MA1528.2 14 bp overlap

Motif DE_24h DE_24h-NFYB_MA0502.3 9 bp overlap

NHLH2 1 dataset

Motif DE_24h DE_24h-NHLH2_MA1529.2 16 bp overlap

Neurod2 1 dataset

Motif DE_24h DE_24h-Neurod2_MA1993.2 6 bp overlap

Nfatc1 1 dataset

Motif DE_24h DE_24h-Nfatc1_MA0624.3 6 bp overlap

Olig2 1 dataset

Motif DE_24h DE_24h-Olig2_MA1997.2 6 bp overlap

PLAGL2 1 dataset

Motif DE_24h DE_24h-PLAGL2_MA1548.2 8 bp overlap

POU2F3 1 dataset

Motif DE_24h DE_24h-POU2F3_MA0627.3 9 bp overlap

POU3F1 1 dataset

Motif DE_24h DE_24h-POU3F1_MA0786.2 10 bp overlap

POU5F1 3 datasets

Motif DE_24h DE_24h-POU5F1_MA1115.2 7 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 630 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 630 bp overlap

PRDM4 3 datasets

ChIP HCT-116_B3 GSE152144.PRDM4.HCT-116_B3 138 bp overlap

ChIP HEK293 ENCFF069PHD 320 bp overlap

ChIP HepG2 ENCFF236NMN 207 bp overlap

PTBP1 5 datasets

ChIP K-562 ENCSR948KMB.PTBP1.K-562 144 bp overlap

ChIP K-562 GSE120104.PTBP1.K-562 144 bp overlap

ChIP K562 ENCFF238NLS 211 bp overlap

ChIP K562 ENCFF238NLS 105 bp overlap

ChIP K562 ENCFF773HPT 308 bp overlap

Pou5f1::Sox2 1 dataset

Motif DE_24h DE_24h-Pou5f1Sox2_MA0142.1 15 bp overlap

Ptf1A 1 dataset

Motif DE_24h DE_24h-Ptf1A_MA1620.2 8 bp overlap

RAD21 2 datasets

ChIP H1 ENCFF698EWO 241 bp overlap

ChIP H1 ENCFF967OJF 245 bp overlap

Motif DE_24h DE_24h-RARA_MA0730.1 17 bp overlap

RARA::RXRG 1 dataset

Motif DE_24h DE_24h-RARARXRG_MA1149.2 17 bp overlap

RREB1 1 dataset

Motif DE_24h DE_24h-RREB1_MA0073.2 19 bp overlap

RUNX1 1 dataset

ChIP 697 GSE138031.RUNX1.697 94 bp overlap

RUNX1T1 1 dataset

ChIP Kasumi-1 GSE115115.RUNX1T1.Kasumi-1 106 bp overlap

RUNX3 1 dataset

ChIP GM12878 ENCFF395WHA 285 bp overlap

Motif DE_24h DE_24h-Rarb_MA0858.1 17 bp overlap

ChIP WTC11 ENCFF891HYW 377 bp overlap

SMAD2_3 7 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 630 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 562 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 630 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 618 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 485 bp overlap

ChIP ESC S23-ESC-d0-SMAD2_3-exp1 577 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 630 bp overlap

SMARCA5 2 datasets

ChIP K562 ENCFF936KHY 217 bp overlap

ChIP K562 ENCFF936KHY 183 bp overlap

SMARCC1 2 datasets

ChIP DE_D1 S15-DE-d1-BAF155-exp1 311 bp overlap

ChIP ESC S25-ESC-d0-BAF155-exp1 510 bp overlap

SOX12 1 dataset

Motif DE_24h DE_24h-SOX12_MA1561.2 10 bp overlap

SOX14 1 dataset

Motif DE_24h DE_24h-SOX14_MA1562.2 9 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 606 bp overlap

SOX18 1 dataset

Motif DE_24h DE_24h-SOX18_MA1563.2 8 bp overlap

Motif DE_24h DE_24h-SOX4_MA0867.3 8 bp overlap

Motif DE_24h DE_24h-SOX8_MA0868.3 7 bp overlap

Motif DE_24h DE_24h-SOX9_MA0077.2 8 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

Sox11 1 dataset

Motif DE_24h DE_24h-Sox11_MA0869.3 8 bp overlap

Sox17 1 dataset

Motif DE_24h DE_24h-Sox17_MA0078.3 10 bp overlap

Motif DE_24h DE_24h-Sox5_MA0087.3 8 bp overlap

Motif DE_24h DE_24h-Sox6_MA0515.1 10 bp overlap

Motif DE_24h DE_24h-Sox7_MA2095.1 10 bp overlap

Motif DE_24h DE_24h-Spz1_MA0111.1 11 bp overlap

TAF1 2 datasets

ChIP H1 ENCFF478SZO 485 bp overlap

ChIP H1 ENCFF478SZO 243 bp overlap

TCF12 1 dataset

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 125 bp overlap

Motif DE_24h DE_24h-TCF4_MA0830.3 8 bp overlap

TCF7L2 2 datasets

ChIP HCT-116 ENCSR000EUV.TCF7L2.HCT-116 137 bp overlap

ChIP HCT116 ENCFF038POZ 218 bp overlap

TEAD4 1 dataset

ChIP ESC S26-ESC-d0-TEAD4-exp1 434 bp overlap

TFAP2A 2 datasets

Motif DE_24h DE_24h-TFAP2A_MA0810.2 11 bp overlap

Motif DE_24h DE_24h-TFAP2A_MA0872.1 13 bp overlap

TFAP2B 2 datasets

Motif DE_24h DE_24h-TFAP2B_MA0811.2 11 bp overlap

Motif DE_24h DE_24h-TFAP2B_MA0813.1 13 bp overlap

TFAP2C 1 dataset

Motif DE_24h DE_24h-TFAP2C_MA0815.1 13 bp overlap

TFAP4::FLI1 1 dataset

Motif DE_24h DE_24h-TFAP4FLI1_MA1967.2 14 bp overlap

Tcf12 1 dataset

Motif DE_24h DE_24h-Tcf12_MA0521.3 6 bp overlap

Twist2 1 dataset

Motif DE_24h DE_24h-Twist2_MA0633.3 6 bp overlap

VEZF1 1 dataset

Motif DE_24h DE_24h-VEZF1_MA1578.2 6 bp overlap

ZBTB18 1 dataset

Motif DE_24h DE_24h-ZBTB18_MA0698.2 11 bp overlap

ZBTB33 1 dataset

ChIP K562 ENCFF427SDV 505 bp overlap

ZEB1 2 datasets

Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap

Motif DE_24h DE_24h-ZEB1_MA0103.4 6 bp overlap

ZFP36 5 datasets

ChIP A549 ENCFF505LUC 135 bp overlap

ChIP GM12878 ENCFF234WRG 158 bp overlap

ChIP HeLa-S3 ENCFF281CEA 123 bp overlap

ChIP K-562 ENCSR776CYN.ZFP36.K-562 122 bp overlap

ChIP K562 ENCFF255RZG 160 bp overlap

ChIP HEK293 ENCFF033NQQ 239 bp overlap

Motif DE_24h DE_24h-ZIC4_MA0751.2 14 bp overlap

ZKSCAN5 1 dataset

Motif DE_24h DE_24h-ZKSCAN5_MA1652.2 9 bp overlap

ZMYM3 1 dataset

ChIP K562 ENCFF361LXT 171 bp overlap

ZNF184 1 dataset

ChIP WTC11 ENCFF352POG 497 bp overlap

ZNF263 2 datasets

ChIP K562 ENCFF640RNA 222 bp overlap

ChIP WTC11 ENCFF893RTM 279 bp overlap

ZNF320 1 dataset

Motif DE_24h DE_24h-ZNF320_MA1976.2 20 bp overlap

ZNF423 1 dataset

ChIP WTC11 ENCFF574PBR 145 bp overlap

ZNF436 1 dataset

ChIP K562 ENCFF717FWZ 155 bp overlap

ZNF454 1 dataset

Motif DE_24h DE_24h-ZNF454_MA1712.2 17 bp overlap

ZNF530 1 dataset

Motif DE_24h DE_24h-ZNF530_MA1981.2 14 bp overlap

ZNF682 1 dataset

Motif DE_24h DE_24h-ZNF682_MA1599.2 11 bp overlap

ZNF692 1 dataset

Motif DE_24h DE_24h-ZNF692_MA1986.2 8 bp overlap

Zfp335 1 dataset

Motif DE_24h DE_24h-Zfp335_MA2002.2 7 bp overlap