chr17:81,648,048–81,648,550

chr17 : 81,648,048 – 81,648,550

502 bp 88 TFs 24 linked genes

This 502 bp open chromatin element is linked to 24 target genes and is bound by 88 transcription factors.

Linked Genes

24 genes

Gene	Expression	Dist. to TSS	Distance	Link type
NPLOC4		213 bp	At TSS	Multiome
PDE6G		5.1 kb	Proximal	Proximity
TSPAN10		11.1 kb	Distal	Multiome
OXLD1		18.4 kb	Distal	Multiome
CCDC137		18.5 kb	Distal	Multiome
ARL16		35.5 kb	Distal	Multiome
HGS		35.7 kb	Distal	Multiome
ENSG00000262049		55.1 kb	Distal	Multiome
MRPL12		55.1 kb	Distal	Multiome
SLC25A10		64.0 kb	Distal	Multiome
FAAP100		95.9 kb	Distal	Multiome
ACTG1		135.5 kb	Distal	Multiome
MCRIP1		185.0 kb	Distal	Multiome
P4HB		212.3 kb	Distal	Multiome
ARHGDIA		223.1 kb	Distal	Multiome
ENSG00000263731		232.9 kb	Distal	Multiome
ALYREF		243.3 kb	Distal	Multiome
ANAPC11		243.5 kb	Distal	Multiome
BAHCC1		252.8 kb	Distal	Multiome
PCYT2		263.2 kb	Distal	Multiome
SIRT7		269.9 kb	Distal	Multiome
MAFG		279.5 kb	Distal	Multiome
MILIP		279.6 kb	Distal	Multiome
PYCR1		289.0 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

88 transcription factors

ChIP MDA-MB-453_FOXA1 ERP003503.AR.MDA-MB-453_FOXA1 89 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 107 bp overlap

ChIP prostate_fetal-fibroblast GSE90772.AR.prostate_fetal-fibroblast 226 bp overlap

Ahr::Arnt 4 datasets

Motif DE_24h DE_24h-AhrArnt_MA0006.2 5 bp overlap

Motif DE_24h DE_24h-AhrArnt_MA0006.2 5 bp overlap

Motif ES_0h ES_0h-AhrArnt_MA0006.2 5 bp overlap

Motif ES_0h ES_0h-AhrArnt_MA0006.2 5 bp overlap

BCL11A 1 dataset

ChIP MDA-MB-157 ERP003925.BCL11A.MDA-MB-157 311 bp overlap

BCOR 3 datasets

ChIP WA01 GSE104690.BCOR.WA01 392 bp overlap

ChIP WA01_KDM2B_KO GSE104690.BCOR.WA01_KDM2B_KO 188 bp overlap

ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 502 bp overlap

BRCA1 1 dataset

ChIP SH-EP_pWZL-MYCNwt GSE111905.BRCA1.SH-EP_pWZL-MYCNwt 107 bp overlap

BRD4 10 datasets

ChIP CLL_patient1_4h_CpG GSE109411.BRD4.CLL_patient1_4h_CpG 57 bp overlap

ChIP COLO-741 GSE73319.BRD4.COLO-741 196 bp overlap

ChIP MCF-10A ERP003925.BRD4.MCF-10A 466 bp overlap

ChIP MDA-MB-157 ERP003925.BRD4.MDA-MB-157 222 bp overlap

ChIP T-47D ERP003925.BRD4.T-47D 322 bp overlap

ChIP hESC GSE33281.BRD4.hESC 61 bp overlap

ChIP hESC GSE33281.BRD4.hESC 75 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 291 bp overlap

ChIP retina_AB1-FW20 GSE86981.BRD4.retina_AB1-FW20 215 bp overlap

ChIP retina_AB1-RB GSE86981.BRD4.retina_AB1-RB 502 bp overlap

ChIP ME-1 GSE46044.CBFB.ME-1 257 bp overlap

ChIP HCT-116 GSE72622.CDK9.HCT-116 252 bp overlap

CEBPB 1 dataset

ChIP WA01 ENCSR000EBV.CEBPB.WA01 111 bp overlap

ChIP hMSC-TERT GSE89179.CHD1.hMSC-TERT 502 bp overlap

CTCF 22 datasets

ChIP 786-O_NORMOXIA GSE78113.CTCF.786-O_NORMOXIA 323 bp overlap

ChIP GM09237_B-lymphocytes GSE111170.CTCF.GM09237_B-lymphocytes 168 bp overlap

ChIP GM23338 ENCFF772DML 201 bp overlap

ChIP Kelly_sensitive GSE103030.CTCF.Kelly_sensitive 193 bp overlap

ChIP SK-N-SH ENCSR000DXQ.CTCF.SK-N-SH 96 bp overlap

ChIP T-47D_NaCl-isotonic GSE111923.CTCF.T-47D_NaCl-isotonic 359 bp overlap

ChIP T-47D_NaCl-isotonic-triptolide GSE111923.CTCF.T-47D_NaCl-isotonic-triptolide 260 bp overlap

ChIP T-47D_NaCl-triptolide GSE111923.CTCF.T-47D_NaCl-triptolide 470 bp overlap

ChIP T-47D_Y537S GSE148277.CTCF.T-47D_Y537S 117 bp overlap

ChIP WA01_MESEN_STEM GSE52457.CTCF.WA01_MESEN_STEM 170 bp overlap

ChIP endodermal cell ENCFF471YCZ 430 bp overlap

ChIP fibroblast_GINGIVA ENCSR000DPS.CTCF.fibroblast_GINGIVA 108 bp overlap

ChIP fibroblast_SKIN_LEG ENCSR000DPG.CTCF.fibroblast_SKIN_LEG 93 bp overlap

ChIP hESC_NAIVE GSE69646.CTCF.hESC_NAIVE 244 bp overlap

ChIP hiPSC_CVI GSE106870.CTCF.hiPSC_CVI 363 bp overlap

ChIP hiPSC_IB7 GSE106870.CTCF.hiPSC_IB7 124 bp overlap

ChIP hiPSC_IIA11 GSE106870.CTCF.hiPSC_IIA11 242 bp overlap

ChIP hiPSC_IV8 GSE106870.CTCF.hiPSC_IV8 147 bp overlap

ChIP hiPSC_parental-line GSE106870.CTCF.hiPSC_parental-line 162 bp overlap

ChIP keratinocyte GSE154221.CTCF.keratinocyte 265 bp overlap

ChIP neuron_bipolar_doxy_4d ENCSR619IUE.CTCF.neuron_bipolar_doxy_4d 108 bp overlap

ChIP primary-glioblastoma_G567 GSE121601.CTCF.primary-glioblastoma_G567 162 bp overlap

CTCFL 2 datasets

ChIP K-562 GSE70764.CTCFL.K-562 89 bp overlap

ChIP K-562 GSE70764.CTCFL.K-562 255 bp overlap

Cebpa 2 datasets

ChIP BLaER1 ENCFF031ISE 502 bp overlap

ChIP BLaER1 ENCFF460KDD 238 bp overlap

ChIP WTC11 ENCFF994SXO 101 bp overlap

E2F5 2 datasets

ChIP WTC11 ENCFF449LLF 252 bp overlap

ChIP WTC11 ENCFF449LLF 453 bp overlap

ChIP WA01 ENCSR000BSI.E2F6.WA01 182 bp overlap

ChIP CD34_NR29 GSE23730.ERG.CD34_NR29 502 bp overlap

ChIP K-562 GSE23730.ERG.K-562 252 bp overlap

ChIP K-562_DOX GSE23730.ERG.K-562_DOX 208 bp overlap

ChIP Ishikawa GSE99905.ESR1.Ishikawa 198 bp overlap

ESRRA 2 datasets

ChIP WTC11 ENCFF591YCA 335 bp overlap

ChIP WTC11 ENCFF591YCA 349 bp overlap

ETV5::FIGLA 1 dataset

Motif ES_0h ES_0h-ETV5FIGLA_MA1945.2 14 bp overlap

EZH2 26 datasets

ChIP GM23248 ENCFF404ZHM 365 bp overlap

ChIP GM23338 ENCFF613YON 51 bp overlap

ChIP GM23338 ENCSR045YHA.EZH2.GM23338 236 bp overlap

ChIP HUVEC-C GSE109625.EZH2.HUVEC-C 502 bp overlap

ChIP HUVEC-C_VEGF_12h GSE109625.EZH2.HUVEC-C_VEGF_12h 502 bp overlap

ChIP HUVEC-C_VEGF_1h GSE109625.EZH2.HUVEC-C_VEGF_1h 249 bp overlap

ChIP HUVEC-C_VEGF_4h GSE109625.EZH2.HUVEC-C_VEGF_4h 502 bp overlap

ChIP WA01 ENCSR000ASY.EZH2.WA01 128 bp overlap

ChIP astrocyte ENCFF365JTP 317 bp overlap

ChIP astrocyte ENCFF365JTP 139 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 208 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 352 bp overlap

ChIP endothelial cell of umbilical vein ENCFF539AKL 342 bp overlap

ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 119 bp overlap

ChIP epithelial_mammary ENCSR000ARE.EZH2.epithelial_mammary 217 bp overlap

ChIP fibroblast of dermis ENCFF029VZK 110 bp overlap

ChIP fibroblast of lung ENCFF479BAW 212 bp overlap

ChIP fibroblast of lung ENCFF479BAW 177 bp overlap

ChIP hESC GSE113817.EZH2.hESC 265 bp overlap

ChIP hESC_KO GSE113817.EZH2.hESC_KO 156 bp overlap

ChIP hepatocyte ENCSR384LYW.EZH2.hepatocyte 502 bp overlap

ChIP keratinocyte ENCFF070STK 143 bp overlap

ChIP keratinocyte ENCFF070STK 359 bp overlap

ChIP myotube ENCFF857GWB 326 bp overlap

ChIP myotube ENCFF857GWB 121 bp overlap

ChIP myotube ENCSR000ASZ.EZH2.myotube 502 bp overlap

EZH2_phosphoT487 2 datasets

ChIP GM23248 ENCSR096KPA.EZH2_phosphoT487.GM23248 114 bp overlap

ChIP hepatocyte ENCSR341VYI.EZH2_phosphoT487.hepatocyte 68 bp overlap

ChIP TSU-1621MT GSE60477.FLI1.TSU-1621MT 73 bp overlap

FOXP1 2 datasets

ChIP WTC11 ENCFF338WGC 87 bp overlap

ChIP WTC11 ENCFF338WGC 298 bp overlap

GABPA 1 dataset

ChIP WA01 ENCSR000BIW.GABPA.WA01 111 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 502 bp overlap

HIF1A 1 dataset

ChIP BEAS-2B_arsenic GSE145834.HIF1A.BEAS-2B_arsenic 182 bp overlap

HMGB1 1 dataset

ChIP HUVEC-C GSE98245.HMGB1.HUVEC-C 192 bp overlap

HMGXB4 1 dataset

ChIP WTC11 ENCFF962POR 274 bp overlap

HNRNPK 2 datasets

ChIP Hep-G2 GSE120104.HNRNPK.Hep-G2 210 bp overlap

ChIP Hep-G2 ENCSR519QAA.HNRNPK.Hep-G2 187 bp overlap

JARID2 5 datasets

ChIP AMIPS6 GSE48516.JARID2.AMIPS6 502 bp overlap

ChIP EDOMIPS2 GSE48516.JARID2.EDOMIPS2 338 bp overlap

ChIP MRC-5_IPS25_CTR GSE48515.JARID2.MRC-5_IPS25_CTR 502 bp overlap

ChIP MRC-5_IPS25_MEG3 GSE48515.JARID2.MRC-5_IPS25_MEG3 502 bp overlap

ChIP UTEIPS6 GSE48516.JARID2.UTEIPS6 246 bp overlap

KDM4A 4 datasets

ChIP WA01 ENCSR000AVC.KDM4A.WA01 295 bp overlap

ChIP hiPSC_IA12 GSE106870.KDM4A.hiPSC_IA12 396 bp overlap

ChIP hiPSC_IIA11 GSE106870.KDM4A.hiPSC_IIA11 502 bp overlap

ChIP hiPSC_IID12 GSE106870.KDM4A.hiPSC_IID12 502 bp overlap

KDM5B 2 datasets

ChIP MCF-7 GSE46055.KDM5B.MCF-7 120 bp overlap

ChIP SUM185_SHCTCF GSE46055.KDM5B.SUM185_SHCTCF 130 bp overlap

KLF15 2 datasets

Motif DE_24h DE_24h-KLF15_MA1513.2 8 bp overlap

Motif ES_0h ES_0h-KLF15_MA1513.2 8 bp overlap

KLF6 2 datasets

Motif DE_24h DE_24h-KLF6_MA1517.2 9 bp overlap

Motif ES_0h ES_0h-KLF6_MA1517.2 9 bp overlap

ChIP CCRF-CEM GSE33850.LMO2.CCRF-CEM 181 bp overlap

ChIP THP-1_macrophage_PMA GSE96800.MAF1.THP-1_macrophage_PMA 417 bp overlap

ChIP WTC11 ENCFF223QFY 219 bp overlap

MBD2 2 datasets

ChIP HeLa GSE41006.MBD2.HeLa 166 bp overlap

ChIP HeLa GSE41006.MBD2.HeLa 173 bp overlap

NANOG 2 datasets

ChIP WA01 ERP004238.NANOG.WA01 142 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 94 bp overlap

NCAPH2 1 dataset

ChIP HEK293 GSE97540.NCAPH2.HEK293 476 bp overlap

NFKB1 1 dataset

ChIP HEK293T_2KR GSE129618.NFKB1.HEK293T_2KR 360 bp overlap

NR2F2 2 datasets

ChIP MCF-7_E2 GSE132432.NR2F2.MCF-7_E2 502 bp overlap

ChIP MCF-7_Veh GSE132432.NR2F2.MCF-7_Veh 502 bp overlap

ChIP HEK293_15min GSE89017.OGG1.HEK293_15min 221 bp overlap

PCBP1 2 datasets

ChIP Hep-G2 ENCSR872EVQ.PCBP1.Hep-G2 134 bp overlap

ChIP Hep-G2 GSE120104.PCBP1.Hep-G2 134 bp overlap

PCGF1 1 dataset

ChIP WA01 GSE104690.PCGF1.WA01 502 bp overlap

ChIP WA01 ENCSR000ATK.PHF8.WA01 104 bp overlap

POU2F1 1 dataset

ChIP T-47D GSE148277.POU2F1.T-47D 66 bp overlap

POU5F1 6 datasets

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 120 bp overlap

ChIP BJ1-hTERT GSE92491.POU5F1.BJ1-hTERT 126 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 502 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 442 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 500 bp overlap

ChIP WA01_3IL ERP004238.POU5F1.WA01_3IL 502 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 502 bp overlap

PRDM14 1 dataset

ChIP NCCIT GSE71675.PRDM14.NCCIT 107 bp overlap

RAD21 1 dataset

ChIP hiPSC_CVI GSE106870.RAD21.hiPSC_CVI 164 bp overlap

ChIP fibroblast GSE139053.RNF2.fibroblast 265 bp overlap

RORC 2 datasets

ChIP HCC70 GSE126380.RORC.HCC70 502 bp overlap

ChIP HCC70_XY018 GSE126380.RORC.HCC70_XY018 502 bp overlap

RUNX1 2 datasets

ChIP Jurkat GSE85524.RUNX1.Jurkat 327 bp overlap

ChIP ME-1 GSE46044.RUNX1.ME-1 411 bp overlap

ChIP WA01 GSE104690.RYBP.WA01 502 bp overlap

SETDB1 1 dataset

ChIP K-562 ENCSR000EWI.SETDB1.K-562 502 bp overlap

SIN3A 2 datasets

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 380 bp overlap

ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 268 bp overlap

SIRT6 1 dataset

ChIP SK-MEL-239_L-C-B GSE102813.SIRT6.SK-MEL-239_L-C-B 470 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 426 bp overlap

SMARCA4 2 datasets

ChIP HS-SY-2_HA-tagged GSE108926.SMARCA4.HS-SY-2_HA-tagged 107 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 302 bp overlap

SMARCC1 1 dataset

ChIP HS-SY-2 GSE108025.SMARCC1.HS-SY-2 196 bp overlap

SMC1A 1 dataset

ChIP primary-epidermal-keratinocyte_diff_d0 GSE84657.SMC1A.primary-epidermal-keratinocyte_diff_d0 438 bp overlap

SREBP2 2 datasets

ChIP HCC70 GSE126380.SREBP2.HCC70 502 bp overlap

ChIP HCC70_XY018 GSE126380.SREBP2.HCC70_XY018 502 bp overlap

STAT3 2 datasets

ChIP WA01 ERP004237.STAT3.WA01 101 bp overlap

ChIP WA01 ERP004237.STAT3.WA01 272 bp overlap

SUZ12 2 datasets

ChIP hiPSC GSE124903.SUZ12.hiPSC 502 bp overlap

ChIP hiPSC_WT GSE124903.SUZ12.hiPSC_WT 409 bp overlap

Motif ES_0h ES_0h-Spz1_MA0111.1 11 bp overlap

TAF15 2 datasets

ChIP Hep-G2 ENCSR825MZS.TAF15.Hep-G2 216 bp overlap

ChIP Hep-G2 GSE120104.TAF15.Hep-G2 216 bp overlap

TARDBP 2 datasets

ChIP Hep-G2 ENCSR145CXH.TARDBP.Hep-G2 175 bp overlap

ChIP Hep-G2 GSE120104.TARDBP.Hep-G2 153 bp overlap

ChIP hiPSC_WTa_RNase-neg GSE128135.TBP.hiPSC_WTa_RNase-neg 109 bp overlap

ChIP hiPSC_WTb_RNase-neg GSE128135.TBP.hiPSC_WTb_RNase-neg 264 bp overlap

ChIP hiPSC_WTb_RNase-pos GSE128135.TBP.hiPSC_WTb_RNase-pos 205 bp overlap

TFAP2B 1 dataset

ChIP SK-N-SH ENCFF869XXQ 307 bp overlap

TFAP2C 2 datasets

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 81 bp overlap

ChIP UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc GSE101074.TFAP2C.UCLA1-hESCs_TFAP2C--_1d_TFAP2C_Induc 181 bp overlap

TFAP2E 2 datasets

Motif DE_24h DE_24h-TFAP2E_MA1569.2 9 bp overlap

Motif ES_0h ES_0h-TFAP2E_MA1569.2 9 bp overlap

TFIIIC 1 dataset

ChIP HEK293 GSE119418.TFIIIC.HEK293 502 bp overlap

TGIF2 2 datasets

ChIP WTC11 ENCFF649SHI 129 bp overlap

ChIP WTC11 ENCFF649SHI 328 bp overlap

ChIP WTC11 ENCFF359JCU 371 bp overlap

ChIP keratinocyte GSE33571.TP63.keratinocyte 173 bp overlap

TRIM24 1 dataset

ChIP LNCaP-abl_ETOH GSE69331.TRIM24.LNCaP-abl_ETOH 273 bp overlap

TRIM25 1 dataset

ChIP BT-549 GSE79588.TRIM25.BT-549 491 bp overlap

TRIM28 3 datasets

ChIP AF22 GSE84259.TRIM28.AF22 130 bp overlap

ChIP HCT-116 GSE72622.TRIM28.HCT-116 484 bp overlap

ChIP hESC GSE115387.TRIM28.hESC 502 bp overlap

ChIP SMMC-7721 GSE126982.WDR5.SMMC-7721 502 bp overlap

ZBTB33 3 datasets

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 96 bp overlap

ChIP K-562 ENCSR876GXA.ZBTB33.K-562 248 bp overlap

ChIP K562 ENCFF427SDV 220 bp overlap

ZBTB44 1 dataset

ChIP HEK293 ENCFF560VPN 55 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 323 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 106 bp overlap

ZNF445 1 dataset

ChIP HEK293T GSE78099.ZNF445.HEK293T 502 bp overlap

ZNF649 1 dataset

ChIP HEK293T GSE78099.ZNF649.HEK293T 269 bp overlap

ZNF682 3 datasets

Motif DE_24h DE_24h-ZNF682_MA1599.2 11 bp overlap

Motif ES_0h ES_0h-ZNF682_MA1599.2 11 bp overlap

Motif ES_0h ES_0h-ZNF682_MA1599.2 11 bp overlap

ZNF736 1 dataset

ChIP HEK293T GSE78099.ZNF736.HEK293T 99 bp overlap