chr1:212,214,185–212,214,767

chr1 : 212,214,185 – 212,214,767

582 bp 99 TFs 6 linked genes

This 582 bp open chromatin element is linked to 6 target genes and is bound by 99 transcription factors.

Linked Genes

6 genes

Gene	Expression	Dist. to TSS	Distance	Link type
LINC02608		70.5 kb	Distal	Multiome
PPP2R5A		70.8 kb	Distal	Multiome
DTL		178.9 kb	Distal	Multiome
INTS7		179.1 kb	Distal	Multiome
PACC1		200.3 kb	Distal	Multiome
NENF		218.3 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

99 transcription factors

ADNP 2 datasets

ChIP K562 ENCFF492SKF 582 bp overlap

ChIP K562 ENCFF492SKF 385 bp overlap

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 582 bp overlap

ChIP K562 ENCFF938UXQ 321 bp overlap

ChIP K-562 ENCSR613NUC.ARNT.K-562 276 bp overlap

BCL11A 1 dataset

ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 68 bp overlap

CBFA2T2 2 datasets

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 396 bp overlap

ChIP K562 ENCFF963TXY 381 bp overlap

CBFA2T3 3 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 546 bp overlap

ChIP K-562 GSE142227.CBFA2T3.K-562 160 bp overlap

ChIP K562 ENCFF673OEZ 309 bp overlap

CEBPB 1 dataset

ChIP K-562 ENCSR000BRQ.CEBPB.K-562 149 bp overlap

CLOCK 1 dataset

ChIP BA40_0 GSE96659.CLOCK.BA40_0 98 bp overlap

CTBP1 3 datasets

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 538 bp overlap

ChIP K562 ENCFF403WPG 333 bp overlap

ChIP K562 ENCFF403WPG 532 bp overlap

ChIP K-562_14376 GSE131349.CTCF.K-562_14376 158 bp overlap

CUX1 2 datasets

ChIP K-562 ENCSR000EFO.CUX1.K-562 141 bp overlap

ChIP K562 ENCFF057AIX 345 bp overlap

CXXC5 1 dataset

ChIP K562 ENCFF497CZN 177 bp overlap

Cebpa 1 dataset

ChIP BLaER1 ENCFF844FIP 251 bp overlap

DPF2 3 datasets

ChIP K-562 ENCSR219BXP.DPF2.K-562 447 bp overlap

ChIP K562 ENCFF775HUO 341 bp overlap

ChIP K562 ENCFF775HUO 145 bp overlap

ChIP K-562 ENCSR731LHZ.E4F1.K-562 167 bp overlap

EHMT2 1 dataset

ChIP K-562 ENCSR175EOM.EHMT2.K-562 492 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 322 bp overlap

EP300 1 dataset

ChIP K-562 ENCSR000EGE.EP300.K-562 181 bp overlap

FERD3L 2 datasets

Motif DE_48h DE_48h-FERD3L_MA1485.1 14 bp overlap

Motif DE_60h DE_60h-FERD3L_MA1485.1 14 bp overlap

FIGLA 2 datasets

Motif DE_48h DE_48h-FIGLA_MA0820.2 6 bp overlap

Motif DE_60h DE_60h-FIGLA_MA0820.2 6 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 467 bp overlap

ChIP DE DE-FOXA2-2 365 bp overlap

FOXM1 1 dataset

ChIP K-562 ENCSR429QPP.FOXM1.K-562 209 bp overlap

GATA1 7 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 122 bp overlap

ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 110 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 81 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 326 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 272 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 127 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 202 bp overlap

GATA2 10 datasets

Motif DE_36h DE_36h-GATA2_MA0036.4 7 bp overlap

Motif DE_48h DE_48h-GATA2_MA0036.4 7 bp overlap

Motif DE_60h DE_60h-GATA2_MA0036.4 7 bp overlap

ChIP K-562 ENCSR000DKA.GATA2.K-562 247 bp overlap

ChIP K-562 ENCSR000BKM.GATA2.K-562 125 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 177 bp overlap

ChIP K562 ENCFF088XQT 411 bp overlap

ChIP K562 ENCFF544PCK 251 bp overlap

ChIP K562 ENCFF830LLA 492 bp overlap

ChIP TSU-1621MT GSE60477.GATA2.TSU-1621MT 194 bp overlap

GATA4 7 datasets

ChIP DE DE-GATA4-1 582 bp overlap

ChIP DE DE-GATA4-2 582 bp overlap

Motif DE_36h DE_36h-GATA4_MA0482.3 8 bp overlap

Motif DE_48h DE_48h-GATA4_MA0482.3 8 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

ChIP foregut GSE117136.GATA4.foregut 570 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 501 bp overlap

GATA5 3 datasets

Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap

Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap

Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap

GATA6 14 datasets

ChIP AGS GSE51705.GATA6.AGS 517 bp overlap

ChIP DE DE-GATA6-1 582 bp overlap

ChIP DE DE-GATA6-2 582 bp overlap

Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap

Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 582 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 582 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 582 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 582 bp overlap

ChIP YCC-3 GSE51705.GATA6.YCC-3 156 bp overlap

ChIP foregut GSE117136.GATA6.foregut 553 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 528 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 274 bp overlap

Gata3 3 datasets

Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap

Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

HDAC1 3 datasets

ChIP K-562 ENCSR387UWP.HDAC1.K-562 582 bp overlap

ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 72 bp overlap

ChIP K562 ENCFF928TKZ 62 bp overlap

HDAC2 2 datasets

ChIP K-562 ENCSR893WSB.HDAC2.K-562 582 bp overlap

ChIP K-562 ENCSR075HTM.HDAC2.K-562 425 bp overlap

HDGF 2 datasets

ChIP K-562 ENCSR197ALX.HDGF.K-562 276 bp overlap

ChIP K-562 ENCSR563YDA.HDGF.K-562 316 bp overlap

HMBOX1 1 dataset

ChIP K562 ENCFF055GAZ 176 bp overlap

Hnf1A 2 datasets

Motif DE_48h DE_48h-Hnf1A_MA1991.2 10 bp overlap

Motif DE_60h DE_60h-Hnf1A_MA1991.2 10 bp overlap

ChIP K-562 ENCSR005NMT.ID3.K-562 306 bp overlap

IKZF1 1 dataset

ChIP K-562 ENCSR395HWC.IKZF1.K-562 582 bp overlap

IKZF2 2 datasets

Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap

Motif DE_60h DE_60h-IKZF2_MA2326.1 6 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 355 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 511 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 582 bp overlap

ChIP K-562 ENCSR343ELW.LEF1.K-562 364 bp overlap

ChIP HCT-116 GSE121798.MED1.HCT-116 287 bp overlap

MTA2 3 datasets

ChIP K-562 ENCSR411UYA.MTA2.K-562 414 bp overlap

ChIP K-562 ENCSR113LAS.MTA2.K-562 166 bp overlap

ChIP K562 ENCFF880VZB 52 bp overlap

MTA3 3 datasets

ChIP K-562 ENCSR180NCY.MTA3.K-562 540 bp overlap

ChIP K-562 ENCSR914NEI.MTA3.K-562 370 bp overlap

ChIP K562 ENCFF289UFB 348 bp overlap

NANOG 1 dataset

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 261 bp overlap

NCOR1 4 datasets

ChIP K-562 ENCSR798ILC.NCOR1.K-562 489 bp overlap

ChIP K-562 ENCSR910JAI.NCOR1.K-562 306 bp overlap

ChIP K562 ENCFF788MPU 72 bp overlap

ChIP K562 ENCFF866HRM 89 bp overlap

NFATC3 1 dataset

ChIP K-562 ENCSR670FDA.NFATC3.K-562 259 bp overlap

ChIP K-562 ENCSR796ITY.NFIC.K-562 291 bp overlap

ChIP K-562 GSE26439.NFYA.K-562 244 bp overlap

NFYB 3 datasets

Motif DE_36h DE_36h-NFYB_MA0502.3 9 bp overlap

Motif DE_48h DE_48h-NFYB_MA0502.3 9 bp overlap

Motif DE_60h DE_60h-NFYB_MA0502.3 9 bp overlap

NKX2-4 1 dataset

Motif DE_60h DE_60h-NKX2-4_MA2003.2 8 bp overlap

NR1H2::RXRA 2 datasets

Motif DE_48h DE_48h-NR1H2RXRA_MA0115.1 17 bp overlap

Motif DE_60h DE_60h-NR1H2RXRA_MA0115.1 17 bp overlap

NR2F1 3 datasets

Motif DE_48h DE_48h-NR2F1_MA1537.2 13 bp overlap

Motif DE_60h DE_60h-NR2F1_MA1537.2 13 bp overlap

ChIP K-562 ENCSR970NKQ.NR2F1.K-562 470 bp overlap

NR2F2 1 dataset

ChIP K-562 ENCSR000BRS.NR2F2.K-562 205 bp overlap

ONECUT1 2 datasets

Motif DE_48h DE_48h-ONECUT1_MA0679.3 9 bp overlap

Motif DE_60h DE_60h-ONECUT1_MA0679.3 9 bp overlap

ONECUT2 2 datasets

Motif DE_48h DE_48h-ONECUT2_MA0756.3 8 bp overlap

Motif DE_60h DE_60h-ONECUT2_MA0756.3 8 bp overlap

PATZ1 2 datasets

Motif DE_48h DE_48h-PATZ1_MA1961.2 11 bp overlap

Motif DE_60h DE_60h-PATZ1_MA1961.2 11 bp overlap

PHOX2B 2 datasets

Motif DE_48h DE_48h-PHOX2B_MA0681.3 12 bp overlap

Motif DE_60h DE_60h-PHOX2B_MA0681.3 12 bp overlap

POLR2A 2 datasets

ChIP K562 ENCFF514URW 50 bp overlap

ChIP K562 ENCFF836GHX 502 bp overlap

Plagl1 2 datasets

Motif DE_48h DE_48h-Plagl1_MA1615.2 8 bp overlap

Motif DE_60h DE_60h-Plagl1_MA1615.2 8 bp overlap

Pou5f1::Sox2 3 datasets

Motif DE_36h DE_36h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif DE_48h DE_48h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif DE_60h DE_60h-Pou5f1Sox2_MA0142.1 15 bp overlap

SMAD2 1 dataset

ChIP endoderm GSE29422.SMAD2.endoderm 137 bp overlap

SMAD2-3 3 datasets

ChIP HGrC1_EV GSE138496.SMAD2-3.HGrC1_EV 113 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 582 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 582 bp overlap

SMAD2_3 6 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 554 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 582 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 402 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 57 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 427 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 424 bp overlap

SMAD3 1 dataset

ChIP endoderm GSE29422.SMAD3.endoderm 245 bp overlap

SMAD4 2 datasets

ChIP K562 ENCFF628RBP 87 bp overlap

ChIP K562 ENCFF628RBP 287 bp overlap

SMARCA4 1 dataset

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 552 bp overlap

SMARCC1 1 dataset

ChIP DE_D1 S15-DE-d1-BAF155-exp1 500 bp overlap

SMARCE1 1 dataset

ChIP K-562 ENCSR157TCS.SMARCE1.K-562 492 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 216 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 582 bp overlap

SOX6 2 datasets

ChIP K-562 ENCSR788RSW.SOX6.K-562 490 bp overlap

ChIP K562 ENCFF059YCJ 419 bp overlap

SOX9 2 datasets

Motif DE_48h DE_48h-SOX9_MA0077.2 8 bp overlap

Motif DE_60h DE_60h-SOX9_MA0077.2 8 bp overlap

ChIP CD34_FETAL GSE70660.SPI1.CD34_FETAL 95 bp overlap

Sox17 2 datasets

Motif DE_48h DE_48h-Sox17_MA0078.3 10 bp overlap

Motif DE_60h DE_60h-Sox17_MA0078.3 10 bp overlap

Sox7 2 datasets

Motif DE_48h DE_48h-Sox7_MA2095.1 10 bp overlap

Motif DE_60h DE_60h-Sox7_MA2095.1 10 bp overlap

Spz1 2 datasets

Motif DE_48h DE_48h-Spz1_MA0111.1 11 bp overlap

Motif DE_60h DE_60h-Spz1_MA0111.1 11 bp overlap

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 216 bp overlap

TAL1 13 datasets

ChIP CD34 GSE52924.TAL1.CD34 112 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 50 bp overlap

ChIP K-562 ENCSR106FRG.TAL1.K-562 484 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 368 bp overlap

ChIP K-562 ENCSR000EHB.TAL1.K-562 206 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 252 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 251 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 246 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 306 bp overlap

ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 222 bp overlap

ChIP K562 ENCFF620GMX 385 bp overlap

ChIP K562 ENCFF661CCK 277 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 123 bp overlap

TCF12 3 datasets

ChIP K-562 ENCSR744WOO.TCF12.K-562 362 bp overlap

ChIP K562 ENCFF909RDY 397 bp overlap

ChIP K562 ENCFF931DJY 391 bp overlap

TCF3 2 datasets

ChIP K-562 ENCSR970OJY.TCF3.K-562 251 bp overlap

ChIP K562 ENCFF319QZT 381 bp overlap

TCF7L2 3 datasets

Motif DE_36h DE_36h-TCF7L2_MA0523.2 9 bp overlap

Motif DE_48h DE_48h-TCF7L2_MA0523.2 9 bp overlap

Motif DE_60h DE_60h-TCF7L2_MA0523.2 9 bp overlap

TEAD4 1 dataset

ChIP K562 ENCFF673NIK 365 bp overlap

TFAP2A 1 dataset

ChIP WA09 GSE105081.TFAP2A.WA09 194 bp overlap

TFAP2C 1 dataset

ChIP WA09 GSE105081.TFAP2C.WA09 233 bp overlap

ChIP K562 ENCFF728FRA 136 bp overlap

TRIM24 3 datasets

ChIP K-562 ENCSR957LDM.TRIM24.K-562 276 bp overlap

ChIP K-562 ENCSR907MZR.TRIM24.K-562 264 bp overlap

ChIP K562 ENCFF284DKY 381 bp overlap

TRIM28 1 dataset

ChIP K562 ENCFF172UPN 53 bp overlap

TRPS1 3 datasets

Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap

Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

ChIP K-562 ENCSR000BKT.USF1.K-562 131 bp overlap

ZBTB40 1 dataset

ChIP K-562 ENCSR237VLT.ZBTB40.K-562 136 bp overlap

ZBTB7A 2 datasets

ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 486 bp overlap

ChIP K-562 GSE103445.ZBTB7A.K-562 253 bp overlap

ZEB1 2 datasets

Motif DE_48h DE_48h-ZEB1_MA0103.4 6 bp overlap

Motif DE_60h DE_60h-ZEB1_MA0103.4 6 bp overlap

ZEB2 3 datasets

ChIP K-562 ENCSR004GKA.ZEB2.K-562 582 bp overlap

ChIP K-562 ENCSR322CFO.ZEB2.K-562 475 bp overlap

ChIP K562 ENCFF975RXS 461 bp overlap

ZNF133 3 datasets

ChIP HEK293 ENCFF844RST 202 bp overlap

ChIP HEK293 ENCSR283MWQ.ZNF133.HEK293 285 bp overlap

ChIP HEK293T GSE78099.ZNF133.HEK293T 197 bp overlap

ZNF24 2 datasets

ChIP K-562 ENCSR695EQB.ZNF24.K-562 346 bp overlap

ChIP K562 ENCFF877JCX 356 bp overlap

ZNF282 2 datasets

ChIP K562 ENCFF657WOV 356 bp overlap

ChIP K562 ENCFF657WOV 450 bp overlap

ZNF418 3 datasets

Motif DE_36h DE_36h-ZNF418_MA1980.1 15 bp overlap

Motif DE_48h DE_48h-ZNF418_MA1980.1 15 bp overlap

Motif DE_60h DE_60h-ZNF418_MA1980.1 15 bp overlap

ZNF449 2 datasets

Motif DE_48h DE_48h-ZNF449_MA1656.2 10 bp overlap

Motif DE_60h DE_60h-ZNF449_MA1656.2 10 bp overlap

ZNF677 2 datasets

Motif DE_48h DE_48h-ZNF677_MA2101.1 12 bp overlap

Motif DE_60h DE_60h-ZNF677_MA2101.1 12 bp overlap

Zic2 3 datasets

Motif DE_36h DE_36h-Zic2_MA1629.2 9 bp overlap

Motif DE_48h DE_48h-Zic2_MA1629.2 9 bp overlap

Motif DE_60h DE_60h-Zic2_MA1629.2 9 bp overlap