chr12 : 70,807,958 – 70,808,616
658 bp 109 TFs 1 linked gene
This 658 bp open chromatin element is linked to PTPRB and is bound by 109 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
PTPRB 198.4 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:70,802,958 – 70,813,616
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
109 transcription factors
Source
Cell type
ASH2L 1 dataset
ChIP H1 ENCFF399KAM 658 bp overlap
Ahr::Arnt 2 datasets
Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap
Motif ES_0h ES_0h-AhrArnt_MA0006.2 5 bp overlap
BCL11A 2 datasets
ChIP H1 ENCFF833IPY 145 bp overlap
ChIP H1 ENCFF836SSR 177 bp overlap
BCL6 2 datasets
Motif DE_12h DE_12h-BCL6_MA0463.3 13 bp overlap
Motif ES_0h ES_0h-BCL6_MA0463.3 13 bp overlap
CEBPB 1 dataset
ChIP H1 ENCFF871PTR 261 bp overlap
CREB1 2 datasets
ChIP GM23338 ENCFF432ZEW 305 bp overlap
ChIP WTC11 ENCFF297VCI 371 bp overlap
CREM 1 dataset
ChIP WTC11 ENCFF209ZUE 479 bp overlap
Crx 2 datasets
Motif DE_12h DE_12h-Crx_MA0467.3 6 bp overlap
Motif ES_0h ES_0h-Crx_MA0467.3 6 bp overlap
EP300 2 datasets
ChIP H1 ENCFF927IYK 297 bp overlap
ChIP H1 ENCFF937OPV 205 bp overlap
ESR2 1 dataset
Motif ES_0h ES_0h-ESR2_MA0258.2 15 bp overlap
ETV6 1 dataset
ChIP WTC11 ENCFF812SCD 437 bp overlap
FEZF2 4 datasets
Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap
Motif DE_12h DE_12h-FEZF2_MA2341.1 8 bp overlap
Motif ES_0h ES_0h-FEZF2_MA2341.1 8 bp overlap
Motif ES_0h ES_0h-FEZF2_MA2341.1 8 bp overlap
FOXA1 2 datasets
Motif DE_12h DE_12h-FOXA1_MA0148.5 8 bp overlap
Motif ES_0h ES_0h-FOXA1_MA0148.5 8 bp overlap
FOXF2 2 datasets
Motif DE_12h DE_12h-FOXF2_MA0030.2 9 bp overlap
Motif ES_0h ES_0h-FOXF2_MA0030.2 9 bp overlap
FOXG1 2 datasets
Motif DE_12h DE_12h-FOXG1_MA0613.1 8 bp overlap
Motif ES_0h ES_0h-FOXG1_MA0613.1 8 bp overlap
FOXK1 3 datasets
Motif DE_12h DE_12h-FOXK1_MA0852.3 7 bp overlap
Motif ES_0h ES_0h-FOXK1_MA0852.3 7 bp overlap
ChIP WTC11 ENCFF875IGU 391 bp overlap
FOXK2 2 datasets
Motif DE_12h DE_12h-FOXK2_MA1103.3 7 bp overlap
Motif ES_0h ES_0h-FOXK2_MA1103.3 7 bp overlap
FOXL1 2 datasets
Motif DE_12h DE_12h-FOXL1_MA0033.2 7 bp overlap
Motif ES_0h ES_0h-FOXL1_MA0033.2 7 bp overlap
FOXO4 2 datasets
Motif DE_12h DE_12h-FOXO4_MA0848.1 7 bp overlap
Motif ES_0h ES_0h-FOXO4_MA0848.1 7 bp overlap
FOXO6 2 datasets
Motif DE_12h DE_12h-FOXO6_MA0849.1 7 bp overlap
Motif ES_0h ES_0h-FOXO6_MA0849.1 7 bp overlap
FOXP3 2 datasets
Motif DE_12h DE_12h-FOXP3_MA0850.1 7 bp overlap
Motif ES_0h ES_0h-FOXP3_MA0850.1 7 bp overlap
FOXP4 1 dataset
ChIP WTC11 ENCFF708TAF 377 bp overlap
Foxf1 2 datasets
Motif DE_12h DE_12h-Foxf1_MA1606.2 7 bp overlap
Motif ES_0h ES_0h-Foxf1_MA1606.2 7 bp overlap
Foxj2 2 datasets
Motif DE_12h DE_12h-Foxj2_MA0614.1 8 bp overlap
Motif ES_0h ES_0h-Foxj2_MA0614.1 8 bp overlap
Foxo1 2 datasets
Motif DE_12h DE_12h-Foxo1_MA0480.3 7 bp overlap
Motif ES_0h ES_0h-Foxo1_MA0480.3 7 bp overlap
Foxo3 2 datasets
Motif DE_12h DE_12h-Foxo3_MA0157.4 7 bp overlap
Motif ES_0h ES_0h-Foxo3_MA0157.4 7 bp overlap
GATA3 2 datasets
ChIP MCF-7 ENCFF352QVM 481 bp overlap
ChIP MCF-7 ENCFF437NQS 371 bp overlap
GATA6 2 datasets
ChIP DE_D1 S14-DE-d1-GATA6-exp1 277 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 289 bp overlap
GSC 2 datasets
Motif DE_12h DE_12h-GSC_MA0648.2 6 bp overlap
Motif ES_0h ES_0h-GSC_MA0648.2 6 bp overlap
GSC2 2 datasets
Motif DE_12h DE_12h-GSC2_MA0891.2 6 bp overlap
Motif ES_0h ES_0h-GSC2_MA0891.2 6 bp overlap
HAND2 4 datasets
Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap
Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap
Motif ES_0h ES_0h-HAND2_MA1638.2 6 bp overlap
Motif ES_0h ES_0h-HAND2_MA1638.2 6 bp overlap
HOXB4 2 datasets
Motif DE_12h DE_12h-HOXB4_MA1499.2 6 bp overlap
Motif ES_0h ES_0h-HOXB4_MA1499.2 6 bp overlap
HOXC4 2 datasets
Motif DE_12h DE_12h-HOXC4_MA1504.2 6 bp overlap
Motif ES_0h ES_0h-HOXC4_MA1504.2 6 bp overlap
HOXD4 2 datasets
Motif DE_12h DE_12h-HOXD4_MA1507.2 6 bp overlap
Motif ES_0h ES_0h-HOXD4_MA1507.2 6 bp overlap
INSM1 2 datasets
Motif DE_12h DE_12h-INSM1_MA0155.1 12 bp overlap
Motif ES_0h ES_0h-INSM1_MA0155.1 12 bp overlap
JUN 4 datasets
ChIP DE_D1 S40-DE-d1-JUN-exp2 397 bp overlap
ChIP DE_D2 S02-DE-d2-JUN-exp1 352 bp overlap
ChIP ESC S24-ESC-d0-JUN-exp1 519 bp overlap
ChIP ESC S34-ESC-d0-JUN-exp2 493 bp overlap
KLF1 1 dataset
Motif ES_0h ES_0h-KLF1_MA0493.3 8 bp overlap
KLF2 1 dataset
Motif ES_0h ES_0h-KLF2_MA1515.2 8 bp overlap
KLF4 1 dataset
Motif ES_0h ES_0h-KLF4_MA0039.5 8 bp overlap
KLF5 1 dataset
Motif ES_0h ES_0h-KLF5_MA0599.1 10 bp overlap
KLF6 1 dataset
Motif ES_0h ES_0h-KLF6_MA1517.2 9 bp overlap
MEIS1 2 datasets
Motif DE_12h DE_12h-MEIS1_MA0498.3 5 bp overlap
Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap
MXI1 1 dataset
Motif ES_0h ES_0h-MXI1_MA1108.3 6 bp overlap
NEUROG2 2 datasets
Motif DE_12h DE_12h-NEUROG2_MA1642.2 7 bp overlap
Motif ES_0h ES_0h-NEUROG2_MA1642.2 7 bp overlap
NR1I3 4 datasets
Motif DE_12h DE_12h-NR1I3_MA1534.2 8 bp overlap
Motif DE_12h DE_12h-NR1I3_MA1534.2 8 bp overlap
Motif ES_0h ES_0h-NR1I3_MA1534.2 8 bp overlap
Motif ES_0h ES_0h-NR1I3_MA1534.2 8 bp overlap
NR5A1 2 datasets
Motif DE_12h DE_12h-NR5A1_MA1540.3 12 bp overlap
Motif ES_0h ES_0h-NR5A1_MA1540.3 12 bp overlap
NR6A1 3 datasets
Motif DE_12h DE_12h-NR6A1_MA1541.2 14 bp overlap
Motif DE_12h DE_12h-NR6A1_MA1541.2 14 bp overlap
Motif ES_0h ES_0h-NR6A1_MA1541.2 14 bp overlap
Nr2F6 2 datasets
Motif DE_12h DE_12h-Nr2F6_MA0728.1 15 bp overlap
Motif ES_0h ES_0h-Nr2F6_MA0728.1 15 bp overlap
OTX1 2 datasets
Motif DE_12h DE_12h-OTX1_MA0711.2 6 bp overlap
Motif ES_0h ES_0h-OTX1_MA0711.2 6 bp overlap
OTX2 1 dataset
ChIP WTC11 ENCFF634NAO 138 bp overlap
PAX3 1 dataset
Motif ES_0h ES_0h-PAX3_MA1546.2 14 bp overlap
PITX1 2 datasets
Motif DE_12h DE_12h-PITX1_MA0682.3 6 bp overlap
Motif ES_0h ES_0h-PITX1_MA0682.3 6 bp overlap
PITX2 2 datasets
Motif DE_12h DE_12h-PITX2_MA1547.2 8 bp overlap
Motif ES_0h ES_0h-PITX2_MA1547.2 8 bp overlap
PITX3 2 datasets
Motif DE_12h DE_12h-PITX3_MA0714.2 6 bp overlap
Motif ES_0h ES_0h-PITX3_MA0714.2 6 bp overlap
POU1F1 2 datasets
Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap
Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap
POU2F1 2 datasets
Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap
Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap
POU2F1::SOX2 4 datasets
Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap
Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap
POU2F2 2 datasets
Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap
Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap
POU2F3 2 datasets
Motif DE_12h DE_12h-POU2F3_MA0627.3 9 bp overlap
Motif ES_0h ES_0h-POU2F3_MA0627.3 9 bp overlap
POU3F1 2 datasets
Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap
Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap
POU3F2 2 datasets
Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap
Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap
POU3F3 2 datasets
Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap
Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap
POU3F4 2 datasets
Motif DE_12h DE_12h-POU3F4_MA0789.1 9 bp overlap
Motif ES_0h ES_0h-POU3F4_MA0789.1 9 bp overlap
POU4F2 2 datasets
Motif DE_12h DE_12h-POU4F2_MA0683.2 15 bp overlap
Motif ES_0h ES_0h-POU4F2_MA0683.2 15 bp overlap
POU4F3 2 datasets
Motif DE_12h DE_12h-POU4F3_MA0791.2 12 bp overlap
Motif ES_0h ES_0h-POU4F3_MA0791.2 12 bp overlap
POU5F1 2 datasets
ChIP GM23338 ENCFF333SNB 311 bp overlap
ChIP H1 ENCFF698ZAP 205 bp overlap
POU5F1B 2 datasets
Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap
Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap
POU5F1_M 1 dataset
ChIP DE_D1 DED1-OCT4-M_Batch_II 236 bp overlap
POU6F2 2 datasets
Motif DE_12h DE_12h-POU6F2_MA0793.2 9 bp overlap
Motif ES_0h ES_0h-POU6F2_MA0793.2 9 bp overlap
PPARA::RXRA 1 dataset
Motif ES_0h ES_0h-PPARARXRA_MA1148.2 17 bp overlap
PPARG 1 dataset
Motif ES_0h ES_0h-PPARG_MA0066.2 19 bp overlap
Pou5f1::Sox2 4 datasets
Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap
Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap
Ptf1A 2 datasets
Motif DE_12h DE_12h-Ptf1A_MA1618.2 9 bp overlap
Motif ES_0h ES_0h-Ptf1A_MA1618.2 9 bp overlap
RARA 3 datasets
Motif DE_12h DE_12h-RARA_MA0729.1 18 bp overlap
Motif ES_0h ES_0h-RARA_MA0729.1 18 bp overlap
Motif ES_0h ES_0h-RARA_MA0730.1 17 bp overlap
RARA::RXRA 1 dataset
Motif ES_0h ES_0h-RARARXRA_MA0159.1 17 bp overlap
RARA::RXRG 1 dataset
Motif ES_0h ES_0h-RARARXRG_MA1149.2 17 bp overlap
REL 2 datasets
Motif DE_12h DE_12h-REL_MA0101.1 10 bp overlap
Motif ES_0h ES_0h-REL_MA0101.1 10 bp overlap
RELA 2 datasets
Motif DE_12h DE_12h-RELA_MA0107.1 10 bp overlap
Motif ES_0h ES_0h-RELA_MA0107.1 10 bp overlap
RHOXF1 2 datasets
Motif DE_12h DE_12h-RHOXF1_MA0719.2 6 bp overlap
Motif ES_0h ES_0h-RHOXF1_MA0719.2 6 bp overlap
RXRA 1 dataset
ChIP H1 ENCFF570NHK 201 bp overlap
RXRA::VDR 1 dataset
Motif ES_0h ES_0h-RXRAVDR_MA0074.1 15 bp overlap
Rarb 3 datasets
Motif DE_12h DE_12h-Rarb_MA0857.1 16 bp overlap
Motif ES_0h ES_0h-Rarb_MA0857.1 16 bp overlap
Motif ES_0h ES_0h-Rarb_MA0858.1 17 bp overlap
Rarg 4 datasets
Motif DE_12h DE_12h-Rarg_MA0859.2 15 bp overlap
Motif DE_12h DE_12h-Rarg_MA0860.1 17 bp overlap
Motif ES_0h ES_0h-Rarg_MA0859.2 15 bp overlap
Motif ES_0h ES_0h-Rarg_MA0860.1 17 bp overlap
Rfx6 2 datasets
Motif DE_12h DE_12h-Rfx6_MA1724.2 9 bp overlap
Motif ES_0h ES_0h-Rfx6_MA1724.2 9 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 291 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 445 bp overlap
ChIP ESC S33-ESC-d0-SMAD2_3-exp2 430 bp overlap
SMAD3 1 dataset
ChIP WTC11 ENCFF815YYQ 357 bp overlap
SP1 1 dataset
ChIP H1 ENCFF263FUH 117 bp overlap
TCF12 1 dataset
ChIP H1 ENCFF203EBH 251 bp overlap
TEAD1 3 datasets
Motif DE_12h DE_12h-TEAD1_MA0090.4 9 bp overlap
Motif ES_0h ES_0h-TEAD1_MA0090.4 9 bp overlap
ChIP WTC11 ENCFF502QUV 405 bp overlap
TEAD4 5 datasets
Motif DE_12h DE_12h-TEAD4_MA0809.3 8 bp overlap
ChIP ESC S26-ESC-d0-TEAD4-exp1 390 bp overlap
Motif ES_0h ES_0h-TEAD4_MA0809.3 8 bp overlap
ChIP H1 ENCFF778PAX 109 bp overlap
ChIP WTC11 ENCFF114TZS 341 bp overlap
TFAP2A 2 datasets
Motif DE_12h DE_12h-TFAP2A_MA0810.2 11 bp overlap
Motif ES_0h ES_0h-TFAP2A_MA0810.2 11 bp overlap
TFAP2E 2 datasets
Motif DE_12h DE_12h-TFAP2E_MA1569.2 9 bp overlap
Motif ES_0h ES_0h-TFAP2E_MA1569.2 9 bp overlap
THAP1 4 datasets
Motif DE_12h DE_12h-THAP1_MA0597.3 8 bp overlap
Motif DE_12h DE_12h-THAP1_MA0597.3 8 bp overlap
Motif ES_0h ES_0h-THAP1_MA0597.3 8 bp overlap
Motif ES_0h ES_0h-THAP1_MA0597.3 8 bp overlap
TWIST1 2 datasets
Motif DE_12h DE_12h-TWIST1_MA1123.3 8 bp overlap
Motif ES_0h ES_0h-TWIST1_MA1123.3 8 bp overlap
USF1 2 datasets
ChIP H1 ENCFF090WVU 241 bp overlap
ChIP WTC11 ENCFF699QGS 425 bp overlap
USF2 1 dataset
ChIP WTC11 ENCFF139JAW 417 bp overlap
Vdr 2 datasets
Motif DE_12h DE_12h-Vdr_MA0693.4 7 bp overlap
Motif ES_0h ES_0h-Vdr_MA0693.4 7 bp overlap
ZBTB18 2 datasets
Motif DE_12h DE_12h-ZBTB18_MA0698.2 11 bp overlap
Motif ES_0h ES_0h-ZBTB18_MA0698.2 11 bp overlap
ZBTB43 1 dataset
ChIP WTC11 ENCFF058JUB 476 bp overlap
ZKSCAN1 2 datasets
Motif DE_12h DE_12h-ZKSCAN1_MA1585.2 9 bp overlap
Motif ES_0h ES_0h-ZKSCAN1_MA1585.2 9 bp overlap
ZNF136 4 datasets
Motif DE_12h DE_12h-ZNF136_MA1588.1 15 bp overlap
Motif DE_12h DE_12h-ZNF136_MA1588.1 15 bp overlap
Motif ES_0h ES_0h-ZNF136_MA1588.1 15 bp overlap
Motif ES_0h ES_0h-ZNF136_MA1588.1 15 bp overlap
ZNF213 2 datasets
Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap
Motif ES_0h ES_0h-ZNF213_MA2121.1 12 bp overlap
ZNF281 1 dataset
ChIP WTC11 ENCFF551GAV 377 bp overlap
ZNF35 2 datasets
Motif DE_12h DE_12h-ZNF35_MA2333.1 7 bp overlap
Motif ES_0h ES_0h-ZNF35_MA2333.1 7 bp overlap
ZNF462 1 dataset
ChIP GM23338 ENCFF896CCA 251 bp overlap
ZNF532 1 dataset
ChIP WTC11 ENCFF373VBX 285 bp overlap
ZNF652 2 datasets
Motif DE_12h DE_12h-ZNF652_MA1657.2 9 bp overlap
Motif ES_0h ES_0h-ZNF652_MA1657.2 9 bp overlap
ZNF816 2 datasets
Motif DE_12h DE_12h-ZNF816_MA1719.2 15 bp overlap
Motif ES_0h ES_0h-ZNF816_MA1719.2 15 bp overlap
ZSCAN31 2 datasets
Motif DE_12h DE_12h-ZSCAN31_MA1722.2 18 bp overlap
Motif ES_0h ES_0h-ZSCAN31_MA1722.2 18 bp overlap
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