chr12 : 114,410 – 115,115
705 bp 103 TFs 4 linked genes
This 705 bp open chromatin element is linked to 4 target genes and is bound by 103 transcription factors.
Linked Genes
4 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
ENSG00000290285 160.0 kb Distal Multiome
ENSG00000261799 162.3 kb Distal Multiome
KDM5A 274.5 kb Distal Multiome
CCDC77 286.8 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr12:109,410 – 120,115
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
103 transcription factors
Source
Cell type
ADNP 2 datasets
ChIP K-562 ENCSR440VKE.ADNP.K-562 282 bp overlap
ChIP K562 ENCFF492SKF 487 bp overlap
ARID1B 2 datasets
ChIP K-562 ENCSR822CCM.ARID1B.K-562 209 bp overlap
ChIP K562 ENCFF938UXQ 380 bp overlap
ARNTL 1 dataset
ChIP U2OS_trough_DMOG GSE85096.ARNTL.U2OS_trough_DMOG 229 bp overlap
BCOR 2 datasets
ChIP K-562 ENCSR808AKZ.BCOR.K-562 349 bp overlap
ChIP K562 ENCFF343XWA 273 bp overlap
BRD3 1 dataset
ChIP K-562_DMSO-IFNG GSE138084.BRD3.K-562_DMSO-IFNG 220 bp overlap
BRD4 5 datasets
ChIP K-562_DMSO GSE138084.BRD4.K-562_DMSO 224 bp overlap
ChIP K-562_DMSO-IFNG GSE138084.BRD4.K-562_DMSO-IFNG 233 bp overlap
ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 160 bp overlap
ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 105 bp overlap
ChIP SW480 GSE110473.BRD4.SW480 407 bp overlap
Bcl11B 2 datasets
Motif DE_36h DE_36h-Bcl11B_MA1989.2 9 bp overlap
Motif DE_48h DE_48h-Bcl11B_MA1989.2 9 bp overlap
CBFA2T2 2 datasets
ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 231 bp overlap
ChIP K562 ENCFF963TXY 277 bp overlap
CBFA2T3 2 datasets
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 311 bp overlap
ChIP K562 ENCFF673OEZ 281 bp overlap
CBX1 2 datasets
ChIP K-562 ENCSR948QLZ.CBX1.K-562 215 bp overlap
ChIP K562 ENCFF008KGK 311 bp overlap
CEBPD 1 dataset
ChIP K-562 ENCSR000BVY.CEBPD.K-562 103 bp overlap
CTCF 2 datasets
ChIP K-562_MonoC GSE137216.CTCF.K-562_MonoC 227 bp overlap
ChIP leukemia GSE142161.CTCF.leukemia 179 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF460KDD 358 bp overlap
DNMT3B 1 dataset
ChIP HUES-8_TripleKO-TET1-2-3 GSE99346.DNMT3B.HUES-8_TripleKO-TET1-2-3 211 bp overlap
EHMT2 1 dataset
ChIP K-562 ENCSR175EOM.EHMT2.K-562 90 bp overlap
EOMES 3 datasets
Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap
Motif DE_36h DE_36h-EOMES_MA0800.2 9 bp overlap
Motif DE_48h DE_48h-EOMES_MA0800.2 9 bp overlap
ESRRA 1 dataset
ChIP K-562 ENCSR486IFJ.ESRRA.K-562 213 bp overlap
ETV5::FOXI1 2 datasets
Motif DE_36h DE_36h-ETV5FOXI1_MA1946.2 12 bp overlap
Motif DE_48h DE_48h-ETV5FOXI1_MA1946.2 12 bp overlap
Erg 2 datasets
Motif DE_36h DE_36h-Erg_MA0474.4 10 bp overlap
Motif DE_48h DE_48h-Erg_MA0474.4 10 bp overlap
FOXA2 3 datasets
ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.FOXA2.BJ1-hTERT_FOXA2_GATA4_Coexp 291 bp overlap
ChIP DE DE-FOXA2-1 475 bp overlap
ChIP DE DE-FOXA2-2 529 bp overlap
FOXM1 2 datasets
ChIP K-562 ENCSR429QPP.FOXM1.K-562 221 bp overlap
ChIP K562 ENCFF255RHV 317 bp overlap
FOXO1::ELK1 2 datasets
Motif DE_36h DE_36h-FOXO1ELK1_MA1954.2 13 bp overlap
Motif DE_48h DE_48h-FOXO1ELK1_MA1954.2 13 bp overlap
GATA1 3 datasets
ChIP K-562 GSE107726.GATA1.K-562 287 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 236 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 242 bp overlap
GATA2 9 datasets
ChIP K-562 ENCSR000DKA.GATA2.K-562 330 bp overlap
ChIP K-562 ENCSR000EWG.GATA2.K-562 255 bp overlap
ChIP K-562 ENCSR257RKC.GATA2.K-562 184 bp overlap
ChIP K-562 ENCSR000BKM.GATA2.K-562 170 bp overlap
ChIP K562 ENCFF088XQT 368 bp overlap
ChIP K562 ENCFF513FTZ 229 bp overlap
ChIP K562 ENCFF544PCK 251 bp overlap
ChIP K562 ENCFF830LLA 408 bp overlap
ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 288 bp overlap
GATA3 1 dataset
ChIP breast_tumor_Male_21 GSE104399.GATA3.breast_tumor_Male_21 64 bp overlap
GATA4 2 datasets
ChIP DE DE-GATA4-1 589 bp overlap
ChIP DE DE-GATA4-2 638 bp overlap
GATA5 2 datasets
Motif DE_36h DE_36h-GATA5_MA0766.3 8 bp overlap
Motif DE_48h DE_48h-GATA5_MA0766.3 8 bp overlap
GATA6 11 datasets
ChIP DE DE-GATA6-1 574 bp overlap
ChIP DE DE-GATA6-2 597 bp overlap
Motif DE_36h DE_36h-GATA6_MA1104.3 8 bp overlap
Motif DE_48h DE_48h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 457 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 530 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 337 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 583 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 520 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 463 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 583 bp overlap
GTF2I 1 dataset
ChIP K562 ENCFF539BYI 159 bp overlap
Gata3 2 datasets
Motif DE_36h DE_36h-Gata3_MA0037.5 8 bp overlap
Motif DE_48h DE_48h-Gata3_MA0037.5 8 bp overlap
HDAC1 3 datasets
ChIP K-562 ENCSR387UWP.HDAC1.K-562 385 bp overlap
ChIP K-562 ENCSR711VWL.HDAC1.K-562 157 bp overlap
ChIP K562 ENCFF872AQB 355 bp overlap
HDAC2 8 datasets
ChIP H1 ENCFF353UJQ 173 bp overlap
ChIP K-562 ENCSR075HTM.HDAC2.K-562 396 bp overlap
ChIP K-562 ENCSR893WSB.HDAC2.K-562 232 bp overlap
ChIP K-562 ENCSR000AQG.HDAC2.K-562 218 bp overlap
ChIP K-562 ENCSR000BMG.HDAC2.K-562 164 bp overlap
ChIP K562 ENCFF744ALD 297 bp overlap
ChIP K562 ENCFF919OMP 394 bp overlap
ChIP WA01 ENCSR000AVB.HDAC2.WA01 263 bp overlap
HDGF 1 dataset
ChIP K-562 ENCSR563YDA.HDGF.K-562 239 bp overlap
HIF3A 1 dataset
ChIP Hep-3B2-1-7 GSE129491.HIF3A.Hep-3B2-1-7 58 bp overlap
IKZF1 4 datasets
Motif DE_36h DE_36h-IKZF1_MA1508.2 8 bp overlap
Motif DE_48h DE_48h-IKZF1_MA1508.2 8 bp overlap
ChIP K-562 ENCSR395HWC.IKZF1.K-562 705 bp overlap
ChIP K562 ENCFF771OHZ 239 bp overlap
IKZF2 2 datasets
Motif DE_36h DE_36h-IKZF2_MA2326.1 6 bp overlap
Motif DE_48h DE_48h-IKZF2_MA2326.1 6 bp overlap
JUN 1 dataset
ChIP DE_D2 S02-DE-d2-JUN-exp1 367 bp overlap
KDM1A 14 datasets
ChIP H1 ENCFF696SGD 196 bp overlap
ChIP K-562 ENCSR908CMW.KDM1A.K-562 338 bp overlap
ChIP K-562 ENCSR000ATX.KDM1A.K-562 268 bp overlap
ChIP K-562 ENCSR360HRA.KDM1A.K-562 239 bp overlap
ChIP K-562 GSE117944.KDM1A.K-562 237 bp overlap
ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 260 bp overlap
ChIP K562 ENCFF128TYE 220 bp overlap
ChIP K562 ENCFF133OLU 307 bp overlap
ChIP K562 ENCFF934ZRG 197 bp overlap
ChIP NB4_DMSO GSE128528.KDM1A.NB4_DMSO 191 bp overlap
ChIP SET-2_GSK GSE121424.KDM1A.SET-2_GSK 197 bp overlap
ChIP SU-DHL-4 GSE119038.KDM1A.SU-DHL-4 258 bp overlap
ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 226 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 268 bp overlap
KMT2A 1 dataset
ChIP MOLM-13_VTP-d3-180110 GSE127507.KMT2A.MOLM-13_VTP-d3-180110 61 bp overlap
L3MBTL2 1 dataset
ChIP K-562 ENCSR530XQI.L3MBTL2.K-562 341 bp overlap
LDB1 1 dataset
ChIP K-562 GSE142227.LDB1.K-562 184 bp overlap
MAX 2 datasets
ChIP K-562 ENCSR000EFV.MAX.K-562 158 bp overlap
ChIP K562 ENCFF524IJO 309 bp overlap
MEIS1 1 dataset
Motif DE_36h DE_36h-MEIS1_MA0498.3 5 bp overlap
MIER1 1 dataset
ChIP K-562 ENCSR426MDV.MIER1.K-562 239 bp overlap
MXI1 2 datasets
Motif DE_36h DE_36h-MXI1_MA1108.3 6 bp overlap
Motif DE_48h DE_48h-MXI1_MA1108.3 6 bp overlap
NFIB 2 datasets
Motif DE_48h DE_48h-NFIB_MA1643.2 17 bp overlap
Motif DE_60h DE_60h-NFIB_MA1643.2 17 bp overlap
NFKB1 1 dataset
Motif DE_48h DE_48h-NFKB1_MA0105.4 13 bp overlap
NFKB2 1 dataset
Motif DE_48h DE_48h-NFKB2_MA0778.2 11 bp overlap
NR1H2 1 dataset
ChIP WTC11 ENCFF386FJZ 322 bp overlap
PHF20 1 dataset
ChIP K562 ENCFF436SIT 264 bp overlap
PHIP 1 dataset
ChIP HCT-116_ab833 GSE101646.PHIP.HCT-116_ab833 157 bp overlap
PKNOX1 3 datasets
ChIP K-562 ENCSR115SMW.PKNOX1.K-562 237 bp overlap
ChIP K-562 ENCSR115SMW.PKNOX1.K-562 98 bp overlap
ChIP K562 ENCFF236IUS 353 bp overlap
PTBP1 3 datasets
ChIP K-562 GSE120104.PTBP1.K-562 267 bp overlap
ChIP K-562 ENCSR948KMB.PTBP1.K-562 232 bp overlap
ChIP K562 ENCFF773HPT 321 bp overlap
RBM25 3 datasets
ChIP K-562 ENCSR791OZM.RBM25.K-562 514 bp overlap
ChIP K562 ENCFF248CGR 267 bp overlap
ChIP K562 ENCFF957ORK 262 bp overlap
RCOR1 1 dataset
ChIP K562 ENCFF216EEJ 249 bp overlap
REL 1 dataset
Motif DE_48h DE_48h-REL_MA0101.1 10 bp overlap
RELA 1 dataset
Motif DE_48h DE_48h-RELA_MA0107.1 10 bp overlap
RELB 1 dataset
Motif DE_48h DE_48h-RELB_MA1117.2 7 bp overlap
REST 3 datasets
Motif DE_48h DE_48h-REST_MA0138.3 20 bp overlap
Motif DE_60h DE_60h-REST_MA0138.3 20 bp overlap
ChIP K-562 ENCSR000BMW.REST.K-562 127 bp overlap
Runx1 2 datasets
Motif DE_36h DE_36h-Runx1_MA0002.3 9 bp overlap
Motif DE_48h DE_48h-Runx1_MA0002.3 9 bp overlap
SCRT1 2 datasets
ChIP HEK293 ENCFF513YVP 417 bp overlap
ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 502 bp overlap
SMAD2-3 2 datasets
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 606 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 400 bp overlap
SMAD2_3 3 datasets
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 280 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 556 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 520 bp overlap
SMARCA4 1 dataset
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 330 bp overlap
SMARCA5 2 datasets
ChIP K-562 ENCSR895HSJ.SMARCA5.K-562 334 bp overlap
ChIP K562 ENCFF936KHY 328 bp overlap
SOX13 1 dataset
Motif DE_36h DE_36h-SOX13_MA1120.2 7 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 571 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 502 bp overlap
SOX2 1 dataset
Motif DE_36h DE_36h-SOX2_MA0143.5 7 bp overlap
SOX21 2 datasets
Motif DE_36h DE_36h-SOX21_MA0866.1 15 bp overlap
Motif DE_48h DE_48h-SOX21_MA0866.1 15 bp overlap
SOX6 1 dataset
ChIP K-562 ENCSR788RSW.SOX6.K-562 108 bp overlap
SPIB 2 datasets
Motif DE_36h DE_36h-SPIB_MA0081.3 13 bp overlap
Motif DE_48h DE_48h-SPIB_MA0081.3 13 bp overlap
STAT1_pS727 1 dataset
ChIP SET-2 GSE100566.STAT1_pS727.SET-2 264 bp overlap
STAT3 2 datasets
ChIP T-47D_JC5054 GSE126004.STAT3.T-47D_JC5054 227 bp overlap
ChIP T-47D_JC5056 GSE126004.STAT3.T-47D_JC5056 202 bp overlap
SUZ12 1 dataset
ChIP CRL-7250_shSS18-SSX GSE108025.SUZ12.CRL-7250_shSS18-SSX 289 bp overlap
Sox17 1 dataset
Motif DE_36h DE_36h-Sox17_MA0078.3 10 bp overlap
Sox3 1 dataset
Motif DE_36h DE_36h-Sox3_MA0514.3 7 bp overlap
Sox5 1 dataset
Motif DE_36h DE_36h-Sox5_MA0087.3 8 bp overlap
Spi1 2 datasets
Motif DE_36h DE_36h-Spi1_MA0080.7 13 bp overlap
Motif DE_48h DE_48h-Spi1_MA0080.7 13 bp overlap
TAL1 8 datasets
ChIP K-562 GSE107726.TAL1.K-562 262 bp overlap
ChIP K-562 ENCSR000EHB.TAL1.K-562 204 bp overlap
ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 221 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 242 bp overlap
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 218 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 237 bp overlap
ChIP K-562_sgGal4 GSE132212.TAL1.K-562_sgGal4 165 bp overlap
ChIP K562 ENCFF661CCK 258 bp overlap
TBR1 2 datasets
Motif DE_36h DE_36h-TBR1_MA0802.2 9 bp overlap
Motif DE_48h DE_48h-TBR1_MA0802.2 9 bp overlap
TBX1 1 dataset
Motif DE_36h DE_36h-TBX1_MA0805.1 8 bp overlap
TBX2 2 datasets
Motif DE_36h DE_36h-TBX2_MA0688.2 9 bp overlap
Motif DE_48h DE_48h-TBX2_MA0688.2 9 bp overlap
TBX3 2 datasets
Motif DE_36h DE_36h-TBX3_MA1566.3 9 bp overlap
Motif DE_48h DE_48h-TBX3_MA1566.3 9 bp overlap
TCF12 2 datasets
ChIP K-562 ENCSR744WOO.TCF12.K-562 209 bp overlap
ChIP K562 ENCFF931DJY 317 bp overlap
TCF3 2 datasets
ChIP K-562 ENCSR970OJY.TCF3.K-562 241 bp overlap
ChIP K562 ENCFF319QZT 326 bp overlap
TEAD4 1 dataset
ChIP K562 ENCFF673NIK 301 bp overlap
TFAP2A 2 datasets
Motif DE_48h DE_48h-TFAP2A_MA0872.1 13 bp overlap
Motif DE_60h DE_60h-TFAP2A_MA0872.1 13 bp overlap
TFAP2B 2 datasets
Motif DE_48h DE_48h-TFAP2B_MA0813.1 13 bp overlap
Motif DE_60h DE_60h-TFAP2B_MA0813.1 13 bp overlap
TFAP2C 2 datasets
Motif DE_48h DE_48h-TFAP2C_MA0815.1 13 bp overlap
Motif DE_60h DE_60h-TFAP2C_MA0815.1 13 bp overlap
TRIM24 1 dataset
ChIP K-562 ENCSR907MZR.TRIM24.K-562 144 bp overlap
TRPS1 2 datasets
Motif DE_36h DE_36h-TRPS1_MA1970.2 8 bp overlap
Motif DE_48h DE_48h-TRPS1_MA1970.2 8 bp overlap
ZFP36 1 dataset
ChIP K-562 ENCSR776CYN.ZFP36.K-562 112 bp overlap
ZFX 1 dataset
ChIP HEK293T ENCFF402JZW 72 bp overlap
ZKSCAN8 1 dataset
ChIP K-562 ENCSR448UKK.ZKSCAN8.K-562 214 bp overlap
ZMYM3 4 datasets
ChIP GM12878 GSE97661.ZMYM3.GM12878 260 bp overlap
ChIP K-562 ENCSR102KIN.ZMYM3.K-562 358 bp overlap
ChIP K-562_Ab_JH39-2-2F10 GSE97661.ZMYM3.K-562_Ab_JH39-2-2F10 339 bp overlap
ChIP K562 ENCFF361LXT 274 bp overlap
ZNF24 1 dataset
ChIP K-562 ENCSR695EQB.ZNF24.K-562 223 bp overlap
ZNF282 2 datasets
Motif DE_36h DE_36h-ZNF282_MA1154.2 15 bp overlap
Motif DE_48h DE_48h-ZNF282_MA1154.2 15 bp overlap
ZNF320 2 datasets
Motif DE_48h DE_48h-ZNF320_MA1976.2 20 bp overlap
Motif DE_60h DE_60h-ZNF320_MA1976.2 20 bp overlap
ZNF530 2 datasets
Motif DE_48h DE_48h-ZNF530_MA1981.2 14 bp overlap
Motif DE_60h DE_60h-ZNF530_MA1981.2 14 bp overlap
ZNF652 2 datasets
Motif DE_36h DE_36h-ZNF652_MA1657.2 9 bp overlap
Motif DE_48h DE_48h-ZNF652_MA1657.2 9 bp overlap
ZNF75A 1 dataset
Motif DE_36h DE_36h-ZNF75A_MA2097.1 12 bp overlap
ZNF768 1 dataset
Motif DE_36h DE_36h-ZNF768_MA1731.2 9 bp overlap
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