chr11:76,624,568–76,625,315

chr11 : 76,624,568 – 76,625,315

747 bp 105 TFs 7 linked genes

This 747 bp open chromatin element is linked to 7 target genes and is bound by 105 transcription factors.

Linked Genes

7 genes

Gene	Expression	Dist. to TSS	Distance	Link type
TSKU-AS1		158.1 kb	Distal	Multiome
TSKU		159.1 kb	Distal	Multiome
EMSY		180.0 kb	Distal	Multiome
EMSY-DT		180.3 kb	Distal	Multiome
ACER3		235.9 kb	Distal	Multiome
GVQW3		243.7 kb	Distal	Multiome
THAP12		243.9 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

105 transcription factors

ARID1B 2 datasets

ChIP K-562 ENCSR822CCM.ARID1B.K-562 227 bp overlap

ChIP K562 ENCFF938UXQ 541 bp overlap

BCL11A 4 datasets

ChIP CD34_Day7_30min GSE104676.BCL11A.CD34_Day7_30min 94 bp overlap

ChIP CD34_Day7_90min GSE104676.BCL11A.CD34_Day7_90min 65 bp overlap

ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 54 bp overlap

ChIP CD34_Day9_90min GSE104676.BCL11A.CD34_Day9_90min 56 bp overlap

ChIP HUES-64 GSE104059.BRD1.HUES-64 373 bp overlap

BRD4 7 datasets

ChIP CLL_patient3_4h_CpG GSE109411.BRD4.CLL_patient3_4h_CpG 211 bp overlap

ChIP CLL_patient4_4h_CpG GSE109411.BRD4.CLL_patient4_4h_CpG 167 bp overlap

ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 190 bp overlap

ChIP K-562_iBET-BD2-IFNG GSE138084.BRD4.K-562_iBET-BD2-IFNG 229 bp overlap

ChIP K-562_iBET-IFNG GSE138084.BRD4.K-562_iBET-IFNG 199 bp overlap

ChIP Kelly_sensitive GSE103030.BRD4.Kelly_sensitive 409 bp overlap

ChIP SK-N-BE2-C_Naive-veh GSE107706.BRD4.SK-N-BE2-C_Naive-veh 747 bp overlap

Bcl11B 2 datasets

Motif DE_60h DE_60h-Bcl11B_MA1989.2 9 bp overlap

Motif DE_72h DE_72h-Bcl11B_MA1989.2 9 bp overlap

CBFA2T2 2 datasets

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 211 bp overlap

ChIP K562 ENCFF963TXY 381 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 468 bp overlap

ChIP K562 ENCFF673OEZ 195 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231 GSE112444.CDKN1B.MDA-MB-231 304 bp overlap

CTBP1 2 datasets

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 301 bp overlap

ChIP K562 ENCFF403WPG 545 bp overlap

CTCF 2 datasets

ChIP hESC_D5 GSE116862.CTCF.hESC_D5 371 bp overlap

ChIP keratinocyte_mut2 GSE123711.CTCF.keratinocyte_mut2 148 bp overlap

EP300 2 datasets

ChIP SK-N-SH ENCFF829RWA 377 bp overlap

ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 134 bp overlap

ChIP MCF-7_SHCTR_E2_TNF GSE59530.ESR1.MCF-7_SHCTR_E2_TNF 124 bp overlap

ESR2 2 datasets

Motif DE_60h DE_60h-ESR2_MA0258.2 15 bp overlap

Motif DE_72h DE_72h-ESR2_MA0258.2 15 bp overlap

ESRRG 1 dataset

ChIP cardiomyocyte GSE113760.ESRRG.cardiomyocyte 621 bp overlap

ChIP cardiomyocyte_D9 GSE129986.ETS1.cardiomyocyte_D9 671 bp overlap

FIGLA 1 dataset

Motif DE_72h DE_72h-FIGLA_MA0820.2 6 bp overlap

FOXA1 2 datasets

ChIP LNCaP_S2101-48H GSE114266.FOXA1.LNCaP_S2101-48H 122 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 194 bp overlap

FOXA2 2 datasets

ChIP DE DE-FOXA2-1 496 bp overlap

ChIP DE DE-FOXA2-2 424 bp overlap

Foxl2 2 datasets

Motif DE_60h DE_60h-Foxl2_MA1607.2 10 bp overlap

Motif DE_72h DE_72h-Foxl2_MA1607.2 10 bp overlap

GATA1 8 datasets

ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 73 bp overlap

ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 157 bp overlap

ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 219 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 343 bp overlap

ChIP K-562 ENCSR000EFT.GATA1.K-562 160 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 278 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 228 bp overlap

ChIP K562 ENCFF094CMK 251 bp overlap

GATA2 10 datasets

ChIP ESF GSE108408.GATA2.ESF 208 bp overlap

ChIP K-562 ENCSR000EWG.GATA2.K-562 222 bp overlap

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 242 bp overlap

ChIP SH-SY5Y ENCFF485YIB 405 bp overlap

ChIP SH-SY5Y ENCSR000EYB.GATA2.SH-SY5Y 202 bp overlap

ChIP SK-N-SH ENCFF764OZD 417 bp overlap

ChIP SK-N-SH ENCSR706VOO.GATA2.SK-N-SH 310 bp overlap

ChIP hiPSC_SLC6ebs GSE107639.GATA2.hiPSC_SLC6ebs 450 bp overlap

ChIP hiPSC_SLC9ebs GSE107639.GATA2.hiPSC_SLC9ebs 223 bp overlap

ChIP primary-endometrial-stromal-cell_Veh_P2 GSE145673.GATA2.primary-endometrial-stromal-cell_Veh_P2 435 bp overlap

GATA3 3 datasets

ChIP CLB-Ga GSE90683.GATA3.CLB-Ga 326 bp overlap

ChIP Kelly GSE65664.GATA3.Kelly 251 bp overlap

ChIP SK-N-BE2-C GSE94822.GATA3.SK-N-BE2-C 145 bp overlap

GATA4 19 datasets

ChIP A-549 GSE85002.GATA4.A-549 272 bp overlap

ChIP BJ1-hTERT_FOXA2_GATA4_Coexp GSE92491.GATA4.BJ1-hTERT_FOXA2_GATA4_Coexp 175 bp overlap

ChIP DE DE-GATA4-1 513 bp overlap

ChIP DE DE-GATA4-2 547 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

Motif DE_60h DE_60h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

Motif DE_72h DE_72h-GATA4_MA0482.3 8 bp overlap

ChIP G296S GSE85628.GATA4.G296S 329 bp overlap

ChIP G296S_2 GSE85628.GATA4.G296S_2 329 bp overlap

ChIP G296S_4 GSE85628.GATA4.G296S_4 251 bp overlap

ChIP cardiomyocyte GSE85628.GATA4.cardiomyocyte 239 bp overlap

ChIP cardiomyocyte_1 GSE85628.GATA4.cardiomyocyte_1 240 bp overlap

ChIP cardiomyocyte_5 GSE85628.GATA4.cardiomyocyte_5 366 bp overlap

ChIP cardiomyocyte_7 GSE85628.GATA4.cardiomyocyte_7 279 bp overlap

ChIP foregut GSE117136.GATA4.foregut 507 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 51 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 619 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 570 bp overlap

GATA5 2 datasets

Motif DE_60h DE_60h-GATA5_MA0766.3 8 bp overlap

Motif DE_72h DE_72h-GATA5_MA0766.3 8 bp overlap

GATA6 15 datasets

ChIP AGS GSE51705.GATA6.AGS 262 bp overlap

ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 223 bp overlap

ChIP DE DE-GATA6-1 431 bp overlap

ChIP DE DE-GATA6-2 611 bp overlap

Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap

Motif DE_72h DE_72h-GATA6_MA1104.3 8 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 512 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 408 bp overlap

ChIP PATU8988 GSE47535.GATA6.PATU8988 201 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 493 bp overlap

ChIP foregut GSE117136.GATA6.foregut 624 bp overlap

ChIP foregut_KO GSE117136.GATA6.foregut_KO 515 bp overlap

ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 494 bp overlap

ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 579 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 420 bp overlap

GFI1 2 datasets

Motif DE_60h DE_60h-GFI1_MA0038.3 11 bp overlap

Motif DE_72h DE_72h-GFI1_MA0038.3 11 bp overlap

Gata3 2 datasets

Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap

Motif DE_72h DE_72h-Gata3_MA0037.5 8 bp overlap

HAND2 3 datasets

ChIP CLB-Ga GSE90683.HAND2.CLB-Ga 606 bp overlap

ChIP Kelly GSE94822.HAND2.Kelly 652 bp overlap

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 613 bp overlap

HDAC2 1 dataset

ChIP K-562 ENCSR893WSB.HDAC2.K-562 191 bp overlap

HEXIM1 1 dataset

ChIP HCT-116 GSE72622.HEXIM1.HCT-116 232 bp overlap

Hand1 2 datasets

Motif DE_60h DE_60h-Hand1_MA2123.1 9 bp overlap

Motif DE_72h DE_72h-Hand1_MA2123.1 9 bp overlap

IKZF1 2 datasets

ChIP K-562 ENCSR395HWC.IKZF1.K-562 310 bp overlap

ChIP K562 ENCFF771OHZ 497 bp overlap

IKZF2 1 dataset

Motif DE_72h DE_72h-IKZF2_MA2326.1 6 bp overlap

ChIP K-562 GSE103215.ILF3.K-562 293 bp overlap

ChIP SK-N-BE2-C GSE94822.ISL1.SK-N-BE2-C 186 bp overlap

ChIP MDA-MB-231 GSE112444.JUN.MDA-MB-231 314 bp overlap

ChIP K-562 ENCSR000EGN.JUND.K-562 138 bp overlap

KDM1A 3 datasets

ChIP pancreatic-progenitor_GT GSE104840.KDM1A.pancreatic-progenitor_GT 276 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 163 bp overlap

ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 305 bp overlap

KLF10 2 datasets

Motif DE_60h DE_60h-KLF10_MA1511.2 9 bp overlap

Motif DE_72h DE_72h-KLF10_MA1511.2 9 bp overlap

KLF12 2 datasets

Motif DE_60h DE_60h-KLF12_MA0742.2 9 bp overlap

Motif DE_72h DE_72h-KLF12_MA0742.2 9 bp overlap

KLF14 2 datasets

Motif DE_60h DE_60h-KLF14_MA0740.2 9 bp overlap

Motif DE_72h DE_72h-KLF14_MA0740.2 9 bp overlap

KLF15 1 dataset

Motif DE_72h DE_72h-KLF15_MA1513.2 8 bp overlap

KLF17 1 dataset

Motif DE_72h DE_72h-KLF17_MA1514.2 14 bp overlap

ChIP BJ_INDUCED GSE36570.KLF4.BJ_INDUCED 139 bp overlap

KLF5 2 datasets

Motif DE_60h DE_60h-KLF5_MA0599.1 10 bp overlap

Motif DE_72h DE_72h-KLF5_MA0599.1 10 bp overlap

ChIP K-562 GSE142227.LDB1.K-562 189 bp overlap

Motif DE_60h DE_60h-MAZ_MA1522.2 8 bp overlap

Motif DE_72h DE_72h-MAZ_MA1522.2 8 bp overlap

ChIP K-562 ENCSR000EFX.MAZ.K-562 168 bp overlap

MED1 2 datasets

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 148 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 218 bp overlap

MYCN 3 datasets

ChIP COG-N-415 GSE138295.MYCN.COG-N-415 747 bp overlap

ChIP Kelly GSE94822.MYCN.Kelly 213 bp overlap

ChIP LA-N-5 GSE138295.MYCN.LA-N-5 739 bp overlap

ChIP K-562 GSE26439.NFYA.K-562 188 bp overlap

NKX2-5 2 datasets

ChIP hESC_ab3584 GSE89457.NKX2-5.hESC_ab3584 500 bp overlap

ChIP hESC_sc-14033 GSE89457.NKX2-5.hESC_sc-14033 288 bp overlap

ChIP K-562 ENCSR010KFT.NONO.K-562 156 bp overlap

NR2F2 1 dataset

ChIP hiPSC GSE81585.NR2F2.hiPSC 223 bp overlap

NR3C1 2 datasets

ChIP K-562_GLUCC ERP007081.NR3C1.K-562_GLUCC 163 bp overlap

ChIP breast_tumor_Male_15 GSE104399.NR3C1.breast_tumor_Male_15 439 bp overlap

Nr2e1 2 datasets

Motif DE_60h DE_60h-Nr2e1_MA0676.1 9 bp overlap

Motif DE_72h DE_72h-Nr2e1_MA0676.1 9 bp overlap

OSR2 2 datasets

Motif DE_60h DE_60h-OSR2_MA1646.2 8 bp overlap

Motif DE_72h DE_72h-OSR2_MA1646.2 8 bp overlap

PATZ1 2 datasets

Motif DE_60h DE_60h-PATZ1_MA1961.2 11 bp overlap

Motif DE_72h DE_72h-PATZ1_MA1961.2 11 bp overlap

POU5F1 3 datasets

Motif DE_60h DE_60h-POU5F1_MA1115.2 7 bp overlap

Motif DE_72h DE_72h-POU5F1_MA1115.2 7 bp overlap

ChIP SKM-1 GSE93706.POU5F1.SKM-1 238 bp overlap

RBPJ 4 datasets

Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap

Motif DE_60h DE_60h-RBPJ_MA1116.2 6 bp overlap

Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap

Motif DE_72h DE_72h-RBPJ_MA1116.2 6 bp overlap

RCOR1 2 datasets

ChIP K562 ENCFF216EEJ 297 bp overlap

ChIP SK-N-SH ENCSR009TKN.RCOR1.SK-N-SH 163 bp overlap

REST 2 datasets

Motif DE_60h DE_60h-REST_MA0138.3 20 bp overlap

Motif DE_72h DE_72h-REST_MA0138.3 20 bp overlap

RUNX2 1 dataset

ChIP LNCaP-C4-2B GSE33889.RUNX2.LNCaP-C4-2B 421 bp overlap

Runx1 2 datasets

Motif DE_60h DE_60h-Runx1_MA0002.3 9 bp overlap

Motif DE_72h DE_72h-Runx1_MA0002.3 9 bp overlap

SMAD2 2 datasets

Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap

Motif DE_72h DE_72h-SMAD2_MA1964.2 6 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 657 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 400 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 489 bp overlap

SMAD4 1 dataset

ChIP Caco-2 GSE112946.SMAD4.Caco-2 209 bp overlap

SMARCA4 4 datasets

ChIP K-562 ENCSR587OQL.SMARCA4.K-562 281 bp overlap

ChIP K562 ENCFF506JCB 517 bp overlap

ChIP NGP GSE134626.SMARCA4.NGP 140 bp overlap

ChIP NGP_ARID1A-mut2 GSE134626.SMARCA4.NGP_ARID1A-mut2 150 bp overlap

SMARCB1 1 dataset

ChIP HeLa-S3 ENCSR000EDK.SMARCB1.HeLa-S3 158 bp overlap

SOX10 1 dataset

Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 327 bp overlap

Motif DE_60h DE_60h-SP1_MA0079.5 9 bp overlap

Motif DE_72h DE_72h-SP1_MA0079.5 9 bp overlap

Motif DE_60h DE_60h-SP2_MA0516.3 9 bp overlap

Motif DE_72h DE_72h-SP2_MA0516.3 9 bp overlap

Motif DE_60h DE_60h-SP4_MA0685.2 9 bp overlap

Motif DE_72h DE_72h-SP4_MA0685.2 9 bp overlap

Motif DE_60h DE_60h-SP5_MA1965.2 6 bp overlap

Motif DE_72h DE_72h-SP5_MA1965.2 6 bp overlap

ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 109 bp overlap

STAT3 2 datasets

Motif DE_60h DE_60h-STAT3_MA0144.3 9 bp overlap

Motif DE_72h DE_72h-STAT3_MA0144.3 9 bp overlap

TAL1 7 datasets

ChIP K-562 ENCSR000EHB.TAL1.K-562 175 bp overlap

ChIP K-562 GSE107726.TAL1.K-562 175 bp overlap

ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 221 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 184 bp overlap

ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 234 bp overlap

ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 271 bp overlap

ChIP K562 ENCFF661CCK 277 bp overlap

ChIP hiPSC GSE81585.TBX5.hiPSC 355 bp overlap

TEAD1 1 dataset

ChIP K562 ENCFF465AQA 297 bp overlap

TEAD2 2 datasets

Motif DE_60h DE_60h-TEAD2_MA1121.2 7 bp overlap

Motif DE_72h DE_72h-TEAD2_MA1121.2 7 bp overlap

TEAD4 2 datasets

Motif DE_60h DE_60h-TEAD4_MA0809.3 8 bp overlap

Motif DE_72h DE_72h-TEAD4_MA0809.3 8 bp overlap

ChIP breast-organoid GSE113909.TP63.breast-organoid 127 bp overlap

TRPS1 2 datasets

Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap

Motif DE_72h DE_72h-TRPS1_MA1970.2 8 bp overlap

VEZF1 2 datasets

ChIP K-562 ENCSR189YMA.VEZF1.K-562 267 bp overlap

ChIP K562 ENCFF053XDV 635 bp overlap

ZBTB7A 1 dataset

ChIP K-562 GSE103445.ZBTB7A.K-562 198 bp overlap

Motif DE_72h DE_72h-ZEB1_MA0103.4 6 bp overlap

ChIP K562 ENCFF795CMH 477 bp overlap

ZFP36 1 dataset

ChIP K-562 ENCSR776CYN.ZFP36.K-562 178 bp overlap

ChIP HEK293T_FLAG GSE145160.ZFX.HEK293T_FLAG 366 bp overlap

Motif DE_72h DE_72h-ZIC1_MA0696.1 14 bp overlap

ZKSCAN3 2 datasets

Motif DE_60h DE_60h-ZKSCAN3_MA1973.2 14 bp overlap

Motif DE_72h DE_72h-ZKSCAN3_MA1973.2 14 bp overlap

ZNF148 2 datasets

Motif DE_60h DE_60h-ZNF148_MA1653.2 10 bp overlap

Motif DE_72h DE_72h-ZNF148_MA1653.2 10 bp overlap

ZNF213 2 datasets

Motif DE_60h DE_60h-ZNF213_MA2121.1 12 bp overlap

Motif DE_72h DE_72h-ZNF213_MA2121.1 12 bp overlap

ZNF263 2 datasets

ChIP K-562 ENCSR000EWN.ZNF263.K-562 242 bp overlap

ChIP K-562 ENCSR000EWN.ZNF263.K-562 168 bp overlap

ZNF281 2 datasets

Motif DE_60h DE_60h-ZNF281_MA1630.3 10 bp overlap

Motif DE_72h DE_72h-ZNF281_MA1630.3 10 bp overlap

ChIP K-562 ENCSR195QFV.ZNF3.K-562 157 bp overlap

ZNF316 1 dataset

ChIP K562 ENCFF281INV 285 bp overlap

ZNF317 2 datasets

Motif DE_60h DE_60h-ZNF317_MA1593.2 8 bp overlap

Motif DE_72h DE_72h-ZNF317_MA1593.2 8 bp overlap

ZNF416 2 datasets

Motif DE_60h DE_60h-ZNF416_MA1979.2 10 bp overlap

Motif DE_72h DE_72h-ZNF416_MA1979.2 10 bp overlap

ZNF530 2 datasets

Motif DE_60h DE_60h-ZNF530_MA1981.2 14 bp overlap

Motif DE_72h DE_72h-ZNF530_MA1981.2 14 bp overlap

ZNF675 1 dataset

Motif DE_72h DE_72h-ZNF675_MA1714.2 19 bp overlap

ZNF708 1 dataset

Motif DE_72h DE_72h-ZNF708_MA1730.2 9 bp overlap

ZNF740 1 dataset

Motif DE_72h DE_72h-ZNF740_MA0753.3 10 bp overlap

Zfp809 2 datasets

Motif DE_60h DE_60h-Zfp809_MA2125.1 9 bp overlap

Motif DE_72h DE_72h-Zfp809_MA2125.1 9 bp overlap