chr10 : 70,445,771 – 70,446,449
678 bp 87 TFs 1 linked gene
This 678 bp open chromatin element is linked to NODAL and is bound by 87 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
NODAL 4.1 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr10:70,440,771 – 70,451,449
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
87 transcription factors
Source
Cell type
AR 1 dataset
ChIP prostate_4024_T GSE130408.AR.prostate_4024_T 268 bp overlap
BCL6 1 dataset
ChIP HepG2 ENCFF423EJH 124 bp overlap
BCOR 1 dataset
ChIP WA01_RNF2-R GSE104690.BCOR.WA01_RNF2-R 211 bp overlap
BRD4 3 datasets
ChIP IMR-90_QUIES GSE74238.BRD4.IMR-90_QUIES 140 bp overlap
ChIP RH4_shCHD4 GSE140115.BRD4.RH4_shCHD4 195 bp overlap
ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 220 bp overlap
CASZ1 1 dataset
ChIP rhabdomyosarcoma_Trametinib GSE126143.CASZ1.rhabdomyosarcoma_Trametinib 296 bp overlap
CBFB 1 dataset
ChIP Hep-G2 ENCSR479RZV.CBFB.Hep-G2 226 bp overlap
CBX8 1 dataset
ChIP K-562 ENCSR000ATW.CBX8.K-562 219 bp overlap
CDK8 1 dataset
ChIP myometrium_PT886 GSE128230.CDK8.myometrium_PT886 82 bp overlap
CHD4 1 dataset
ChIP SCMC GSE155861.CHD4.SCMC 250 bp overlap
CREB1 1 dataset
ChIP Hep-G2 ENCSR000BVL.CREB1.Hep-G2 104 bp overlap
CREBBP 1 dataset
ChIP fibroblast_proliferating GSE106146.CREBBP.fibroblast_proliferating 163 bp overlap
CTCF 3 datasets
ChIP chondrocyte ENCFF134ORZ 394 bp overlap
ChIP esophagus-muscularis-mucosa ENCSR443WKD.CTCF.esophagus-muscularis-mucosa 236 bp overlap
ChIP esophagus-muscularis-mucosa ENCSR073TPC.CTCF.esophagus-muscularis-mucosa 247 bp overlap
ELF1 1 dataset
ChIP K-562 ENCSR000BMD.ELF1.K-562 143 bp overlap
EP300 8 datasets
ChIP Hep-G2 ENCSR000BLW.EP300.Hep-G2 164 bp overlap
ChIP HepG2 ENCFF354ACD 325 bp overlap
ChIP SK-N-SH ENCFF451CNG 354 bp overlap
ChIP SK-N-SH ENCFF829RWA 358 bp overlap
ChIP SK-N-SH ENCSR000BUA.EP300.SK-N-SH 177 bp overlap
ChIP SK-N-SH ENCSR000EHV.EP300.SK-N-SH 153 bp overlap
ChIP sigmoid colon ENCFF524QSR 271 bp overlap
ChIP sigmoid colon ENCFF953ZIP 261 bp overlap
ESR1 1 dataset
ChIP MCF-7 GSE68356.ESR1.MCF-7 265 bp overlap
ETV1 4 datasets
ChIP GIST GSE22441.ETV1.GIST 205 bp overlap
ChIP GIST GSE22441.ETV1.GIST 269 bp overlap
ChIP GIST-T1 GSE106624.ETV1.GIST-T1 142 bp overlap
ChIP GIST48_siSCR GSE106624.ETV1.GIST48_siSCR 139 bp overlap
EZH2 1 dataset
ChIP RH30_DMSO GSE85169.EZH2.RH30_DMSO 452 bp overlap
FEZF1 1 dataset
ChIP HEK293 GSE76494.FEZF1.HEK293 226 bp overlap
FOSL2 2 datasets
ChIP NPC_K755R-pos GSE122631.FOSL2.NPC_K755R-pos 264 bp overlap
ChIP NPC_R1159Q GSE122631.FOSL2.NPC_R1159Q 194 bp overlap
FOXF1 1 dataset
ChIP GIST48 GSE106624.FOXF1.GIST48 198 bp overlap
FOXK1 1 dataset
ChIP Hep-G2 ENCSR603BJQ.FOXK1.Hep-G2 231 bp overlap
FOXP1 1 dataset
ChIP Hep-G2 ENCSR369YUK.FOXP1.Hep-G2 135 bp overlap
GATA3 1 dataset
ChIP SK-N-SH ENCFF040SSB 198 bp overlap
GATA4 4 datasets
ChIP DE DE-GATA4-1 445 bp overlap
ChIP DE DE-GATA4-2 461 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 426 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 322 bp overlap
GATA6 12 datasets
ChIP Caco-2_PROLIF GSE23436.GATA6.Caco-2_PROLIF 107 bp overlap
ChIP DE DE-GATA6-1 562 bp overlap
ChIP DE DE-GATA6-2 562 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 661 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 576 bp overlap
ChIP DE_D1 S41-DE-d1-GATA6-exp2 545 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 297 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 678 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 678 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 429 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 370 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 501 bp overlap
HDAC2 1 dataset
ChIP Hep-G2 ENCSR000BMC.HDAC2.Hep-G2 156 bp overlap
HDAC3 2 datasets
ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 238 bp overlap
ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 193 bp overlap
HNF4A 12 datasets
ChIP Caco-2_DIFF GSE23436.HNF4A.Caco-2_DIFF 266 bp overlap
ChIP Caco-2_PROLIF GSE23436.HNF4A.Caco-2_PROLIF 206 bp overlap
ChIP Hep-G2 ENCSR469FBY.HNF4A.Hep-G2 232 bp overlap
ChIP Hep-G2 ERP000209.HNF4A.Hep-G2 203 bp overlap
ChIP Hep-G2 ENCSR000BLF.HNF4A.Hep-G2 161 bp overlap
ChIP Hep-G2 ENCSR000EEU.HNF4A.Hep-G2 160 bp overlap
ChIP HepG2 ENCFF146SSF 361 bp overlap
ChIP HepG2 ENCFF669NAM 261 bp overlap
ChIP gastric-epithelial-cell_OE GSE114018.HNF4A.gastric-epithelial-cell_OE 375 bp overlap
ChIP liver ENCFF354NRH 405 bp overlap
ChIP liver ENCFF449HPV 195 bp overlap
ChIP liver ERP002306.HNF4A.liver 194 bp overlap
HNF4G 3 datasets
ChIP Hep-G2 ENCSR000BNJ.HNF4G.Hep-G2 208 bp overlap
ChIP HepG2 ENCFF323ATZ 291 bp overlap
ChIP liver ENCSR297GII.HNF4G.liver 150 bp overlap
HOXA3 1 dataset
ChIP Hep-G2 ENCSR999JKC.HOXA3.Hep-G2 120 bp overlap
ISL1 1 dataset
ChIP SK-N-SH ENCFF285GEQ 372 bp overlap
JUN 3 datasets
ChIP DE_D1 S08-DE-d1-JUN-exp1 510 bp overlap
ChIP DE_D1 S40-DE-d1-JUN-exp2 447 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 513 bp overlap
JUND 2 datasets
ChIP SK-N-SH ENCFF551NEQ 320 bp overlap
ChIP SK-N-SH ENCSR000BSK.JUND.SK-N-SH 162 bp overlap
MAFB 1 dataset
ChIP islet ERP004003.MAFB.islet 71 bp overlap
MED1 1 dataset
ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 425 bp overlap
MED12 1 dataset
ChIP leiomyoma_PT886 GSE128230.MED12.leiomyoma_PT886 99 bp overlap
MTA2 1 dataset
ChIP RH4 GSE155861.MTA2.RH4 345 bp overlap
MYOD1 8 datasets
ChIP RD GSE137168.MYOD1.RD 440 bp overlap
ChIP RD_shSNAI2 GSE137168.MYOD1.RD_shSNAI2 635 bp overlap
ChIP RH30_DMSO GSE85169.MYOD1.RH30_DMSO 592 bp overlap
ChIP RH4 GSE83726.MYOD1.RH4 195 bp overlap
ChIP RH4 GSE83726.MYOD1.RH4 169 bp overlap
ChIP SMS-CTR GSE137168.MYOD1.SMS-CTR 271 bp overlap
ChIP myoblast GSE50413.MYOD1.myoblast 291 bp overlap
ChIP rhabdomyosarcoma GSE50413.MYOD1.rhabdomyosarcoma 231 bp overlap
MYOG 2 datasets
ChIP RH30_DMSO GSE85169.MYOG.RH30_DMSO 401 bp overlap
ChIP RH4 GSE83726.MYOG.RH4 346 bp overlap
NEUROG2 5 datasets
ChIP MRC-5_NFD_02DPT GSE75910.NEUROG2.MRC-5_NFD_02DPT 229 bp overlap
ChIP MRC-5_NFD_1DPT GSE75910.NEUROG2.MRC-5_NFD_1DPT 211 bp overlap
ChIP MRC-5_N_02DPT GSE75910.NEUROG2.MRC-5_N_02DPT 248 bp overlap
ChIP MRC-5_N_05DPT GSE75910.NEUROG2.MRC-5_N_05DPT 189 bp overlap
ChIP MRC-5_N_1DPT GSE75910.NEUROG2.MRC-5_N_1DPT 173 bp overlap
NFIC 2 datasets
ChIP SK-N-SH ENCFF965AKM 148 bp overlap
ChIP SK-N-SH ENCSR000BSV.NFIC.SK-N-SH 252 bp overlap
NIPBL 1 dataset
ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 190 bp overlap
NR2C2 1 dataset
ChIP Hep-G2 ENCSR559ZKI.NR2C2.Hep-G2 171 bp overlap
NR2F2 6 datasets
ChIP Hep-G2 ENCSR000BVM.NR2F2.Hep-G2 267 bp overlap
ChIP liver ENCFF427MRU 399 bp overlap
ChIP liver ENCFF565JGD 269 bp overlap
ChIP liver ENCFF565JGD 491 bp overlap
ChIP liver ENCSR168SMX.NR2F2.liver 562 bp overlap
ChIP liver ENCSR338MMB.NR2F2.liver 516 bp overlap
NR2F6 4 datasets
ChIP Hep-G2 ENCSR518WPL.NR2F6.Hep-G2 390 bp overlap
ChIP HepG2 ENCFF429VKC 191 bp overlap
ChIP HepG2 ENCFF514UJI 145 bp overlap
ChIP K-562 ENCSR707QWA.NR2F6.K-562 230 bp overlap
NR3C1 1 dataset
ChIP IMR-90_GLUCC ERP007081.NR3C1.IMR-90_GLUCC 136 bp overlap
PAX3-FOXO1 1 dataset
ChIP Hs-352-Sk_PAX3-FOXO1-vector GSE83725.PAX3-FOXO1.Hs-352-Sk_PAX3-FOXO1-vector 177 bp overlap
PAXIP1 1 dataset
ChIP Hep-G2 ENCSR530ARJ.PAXIP1.Hep-G2 259 bp overlap
PBX3 1 dataset
ChIP SK-N-SH ENCFF876BMC 237 bp overlap
PDX1 1 dataset
ChIP hiPSC_derived_PPs GSE106949.PDX1.hiPSC_derived_PPs 152 bp overlap
PGR 1 dataset
ChIP myometrium_NP1 GSE137550.PGR.myometrium_NP1 255 bp overlap
PHF8 1 dataset
ChIP Hep-G2 ENCSR604VAE.PHF8.Hep-G2 171 bp overlap
POLR2A 14 datasets
ChIP SK-N-SH ENCFF683PFH 223 bp overlap
ChIP esophagus muscularis mucosa ENCFF432ZCY 398 bp overlap
ChIP esophagus muscularis mucosa ENCFF759BBR 198 bp overlap
ChIP esophagus muscularis mucosa ENCFF791ZXN 445 bp overlap
ChIP gastroesophageal sphincter ENCFF070PCA 152 bp overlap
ChIP sigmoid colon ENCFF101ILL 321 bp overlap
ChIP sigmoid colon ENCFF725QFT 322 bp overlap
ChIP sigmoid colon ENCFF748YVT 326 bp overlap
ChIP sigmoid colon ENCFF754JQR 168 bp overlap
ChIP stomach ENCFF278MYS 241 bp overlap
ChIP stomach ENCFF820WZN 301 bp overlap
ChIP transverse colon ENCFF607LKE 215 bp overlap
ChIP transverse colon ENCFF610RWV 214 bp overlap
ChIP upper lobe of left lung ENCFF199JUI 333 bp overlap
POU5F1 3 datasets
ChIP DE_D1 DED1-OCT4_Batch_II 647 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 266 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 260 bp overlap
PPARG 1 dataset
ChIP ASC GSE21366.PPARG.ASC 157 bp overlap
PROX1 1 dataset
ChIP HepG2 ENCFF016ZJS 481 bp overlap
RARA 1 dataset
ChIP HepG2 ENCFF582XUA 177 bp overlap
RBPJ 1 dataset
ChIP GSC8-11_12d-das GSE74557.RBPJ.GSC8-11_12d-das 180 bp overlap
RELA 1 dataset
ChIP LNCaP_SICTR_TNFA GSE83860.RELA.LNCaP_SICTR_TNFA 147 bp overlap
RXRA 2 datasets
ChIP HepG2 ENCFF763IEA 127 bp overlap
ChIP liver ENCFF807CIA 397 bp overlap
SIN3A 2 datasets
ChIP SK-N-SH ENCFF931NFD 323 bp overlap
ChIP SK-N-SH ENCSR000BPB.SIN3A.SK-N-SH 204 bp overlap
SMAD2 4 datasets
ChIP endoderm GSE29422.SMAD2.endoderm 191 bp overlap
ChIP hESC GSE29422.SMAD2.hESC 205 bp overlap
ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 632 bp overlap
ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 359 bp overlap
SMAD2-3 4 datasets
ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 257 bp overlap
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 678 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.SMAD2-3.HUES-8_DE_JNKi 678 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 678 bp overlap
SMAD2_3 6 datasets
ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 678 bp overlap
ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 678 bp overlap
ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 678 bp overlap
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 611 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 634 bp overlap
ChIP ESC S33-ESC-d0-SMAD2_3-exp2 255 bp overlap
SMAD3 1 dataset
ChIP hESC GSE29422.SMAD3.hESC 188 bp overlap
SMAD4 4 datasets
ChIP Caco-2 GSE112946.SMAD4.Caco-2 231 bp overlap
ChIP HepG2 ENCFF615GTE 159 bp overlap
ChIP endoderm GSE29422.SMAD4.endoderm 189 bp overlap
ChIP hESC GSE29422.SMAD4.hESC 197 bp overlap
SMARCA2 5 datasets
ChIP NPC_K755R-pos GSE122631.SMARCA2.NPC_K755R-pos 453 bp overlap
ChIP NPC_K755R-pos_ab GSE122631.SMARCA2.NPC_K755R-pos_ab 250 bp overlap
ChIP NPC_K755R-siAP GSE122631.SMARCA2.NPC_K755R-siAP 220 bp overlap
ChIP NPC_K755R-siCT GSE122631.SMARCA2.NPC_K755R-siCT 280 bp overlap
ChIP NPC_R1159Q_ab GSE122631.SMARCA2.NPC_R1159Q_ab 231 bp overlap
SMARCA4 4 datasets
ChIP A-549_AG15686 GSE132290.SMARCA4.A-549_AG15686 82 bp overlap
ChIP NPC_K755R-pos GSE122631.SMARCA4.NPC_K755R-pos 179 bp overlap
ChIP NPC_K755R-siAP GSE122631.SMARCA4.NPC_K755R-siAP 340 bp overlap
ChIP NPC_K755R-siCT GSE122631.SMARCA4.NPC_K755R-siCT 312 bp overlap
SMARCC1 2 datasets
ChIP DE_D1 S10-DE-d1-BAF155-exp1 389 bp overlap
ChIP DE_D1 S15-DE-d1-BAF155-exp1 445 bp overlap
SNAI2 1 dataset
ChIP RD_shSNAI2 GSE137168.SNAI2.RD_shSNAI2 400 bp overlap
SOX8 1 dataset
ChIP RH4 GSE116344.SOX8.RH4 128 bp overlap
SP1 1 dataset
ChIP HepG2 ENCFF123KAM 325 bp overlap
SUZ12 1 dataset
ChIP CRL-7250_shSS18 GSE108025.SUZ12.CRL-7250_shSS18 230 bp overlap
TCF12 1 dataset
ChIP SK-N-SH ENCFF147AHB 300 bp overlap
TCF21 1 dataset
ChIP HCASMC GSE124011.TCF21.HCASMC 199 bp overlap
TCF7L2 2 datasets
ChIP Hep-G2 ENCSR346BOD.TCF7L2.Hep-G2 190 bp overlap
ChIP HepG2 ENCFF510OLG 451 bp overlap
TEAD1 1 dataset
ChIP pancreas_12D ERP008682.TEAD1.pancreas_12D 167 bp overlap
TEAD4 3 datasets
ChIP H1 ENCFF778PAX 245 bp overlap
ChIP SK-N-SH ENCFF754TJT 360 bp overlap
ChIP SK-N-SH ENCSR000BUQ.TEAD4.SK-N-SH 175 bp overlap
TFAP4 4 datasets
ChIP DLD-1 GSE46935.TFAP4.DLD-1 359 bp overlap
ChIP Hep-G2 ENCSR103SZL.TFAP4.Hep-G2 232 bp overlap
ChIP HepG2 ENCFF030SRU 371 bp overlap
ChIP HepG2 ENCFF932XOY 284 bp overlap
TSHZ2 1 dataset
ChIP SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour ENCSR282NLQ.TSHZ2.SK-N-SH_all-trans-retinoic-acid_6-uM_48-hour 167 bp overlap
TWIST1 2 datasets
ChIP SHEP-21N GSE80151.TWIST1.SHEP-21N 181 bp overlap
ChIP SHEP-21N_DOX_0H GSE80151.TWIST1.SHEP-21N_DOX_0H 181 bp overlap
ZBTB20 1 dataset
ChIP HEK293 ENCSR460MBI.ZBTB20.HEK293 254 bp overlap
ZFP64 3 datasets
ChIP HEK293 GSE76494.ZFP64.HEK293 199 bp overlap
ChIP Hep-G2 ENCSR487CPI.ZFP64.Hep-G2 120 bp overlap
ChIP Hep-G2 ENCSR487CPI.ZFP64.Hep-G2 111 bp overlap
ZFP91 3 datasets
ChIP K-562 ENCSR898XMH.ZFP91.K-562 67 bp overlap
ChIP K562 ENCFF501CDP 305 bp overlap
ChIP K562 ENCFF501CDP 100 bp overlap
ZNF217 1 dataset
ChIP Hep-G2 ENCSR055FQB.ZNF217.Hep-G2 169 bp overlap
ZNF24 9 datasets
ChIP HEK293 ENCSR984MDV.ZNF24.HEK293 77 bp overlap
ChIP K-562 ENCSR099NCH.ZNF24.K-562 303 bp overlap
ChIP K-562 ENCSR695EQB.ZNF24.K-562 198 bp overlap
ChIP K-562 ENCSR385AHH.ZNF24.K-562 179 bp overlap
ChIP K-562 ENCSR117WTM.ZNF24.K-562 176 bp overlap
ChIP K562 ENCFF497GLV 124 bp overlap
ChIP K562 ENCFF615YYW 195 bp overlap
ChIP K562 ENCFF781QQQ 70 bp overlap
ChIP K562 ENCFF877JCX 127 bp overlap
ZNF770 3 datasets
ChIP HEK293 ENCFF468FCG 287 bp overlap
ChIP HEK293 ENCSR242BGR.ZNF770.HEK293 265 bp overlap
ChIP HEK293 GSE76494.ZNF770.HEK293 189 bp overlap
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