chr6 : 124,955,086 – 124,955,732

646 bp 96 TFs 2 linked genes

This 646 bp open chromatin element is linked to RNF217 and RNF217-AS1 and is bound by 96 transcription factors.

Linked Genes

2 genes

Gene	Expression	Dist. to TSS	Distance	Link type
RNF217		6.7 kb	Proximal	Proximity
RNF217-AS1		7.4 kb	Proximal	Proximity

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

96 transcription factors

AFF4 1 dataset

ChIP MCF-7 GSE144036.AFF4.MCF-7 312 bp overlap

AR 2 datasets

ChIP LNCaP GSE80256.AR.LNCaP 191 bp overlap

ChIP MCF-7 GSE48930.AR.MCF-7 198 bp overlap

Ahr::Arnt 1 dataset

Motif DE_12h DE_12h-AhrArnt_MA0006.2 5 bp overlap

Atoh1 1 dataset

Motif DE_12h DE_12h-Atoh1_MA1467.3 7 bp overlap

BRD3 1 dataset

ChIP HEK293T GSE39579.BRD3.HEK293T 133 bp overlap

BRD4 8 datasets

ChIP HEK293_Ctrl GSE129407.BRD4.HEK293_Ctrl 334 bp overlap

ChIP HEK293_sgNT GSE129407.BRD4.HEK293_sgNT 89 bp overlap

ChIP K-562_dilution-6-100 GSE140325.BRD4.K-562_dilution-6-100 97 bp overlap

ChIP RH4 GSE83726.BRD4.RH4 250 bp overlap

ChIP RH4_shCHD4 GSE140115.BRD4.RH4_shCHD4 646 bp overlap

ChIP RH4_shscr GSE140115.BRD4.RH4_shscr 646 bp overlap

ChIP VCaP_R1881 GSE148358.BRD4.VCaP_R1881 281 bp overlap

ChIP retina_AB1-FW15 GSE86981.BRD4.retina_AB1-FW15 99 bp overlap

CBFA2T2 1 dataset

ChIP NCCIT GSE71675.CBFA2T2.NCCIT 284 bp overlap

CBX2 1 dataset

ChIP HEK293T GSE34774.CBX2.HEK293T 256 bp overlap

CHD4 2 datasets

ChIP RH5 GSE155861.CHD4.RH5 638 bp overlap

ChIP SCMC GSE155861.CHD4.SCMC 489 bp overlap

CLOCK 1 dataset

ChIP U2OS GSE44236.CLOCK.U2OS 69 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 255 bp overlap

CTCF 1 dataset

ChIP T-47D_NaCl-triptolide GSE111923.CTCF.T-47D_NaCl-triptolide 66 bp overlap

E2F1 1 dataset

ChIP LNCaP_shRB GSE94958.E2F1.LNCaP_shRB 211 bp overlap

E2F4 1 dataset

ChIP K-562 ENCSR000EWL.E2F4.K-562 135 bp overlap

EBF1 1 dataset

ChIP ASC GSE54889.EBF1.ASC 174 bp overlap

ESR1 7 datasets

ChIP Ishikawa_DMSO_D538G_clone3 GSE132426.ESR1.Ishikawa_DMSO_D538G_clone3 294 bp overlap

ChIP Ishikawa_E2-1h GSE129803.ESR1.Ishikawa_E2-1h 235 bp overlap

ChIP Ishikawa_siETV4-72h GSE129803.ESR1.Ishikawa_siETV4-72h 305 bp overlap

ChIP Ishikawa_siNTC-72h GSE129803.ESR1.Ishikawa_siNTC-72h 359 bp overlap

ChIP Ishikawa_siNTC-96h GSE129803.ESR1.Ishikawa_siNTC-96h 330 bp overlap

ChIP MCF-7_aldosterone GSE99626.ESR1.MCF-7_aldosterone 131 bp overlap

ChIP MDA-MB-134-VI_ESTROGEN GSE51022.ESR1.MDA-MB-134-VI_ESTROGEN 604 bp overlap

FOXO1-PAX3 1 dataset

ChIP RH4_DMSO-6H GSE116344.FOXO1-PAX3.RH4_DMSO-6H 350 bp overlap

GATA1 1 dataset

ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 176 bp overlap

GATA3 1 dataset

ChIP Kelly GSE65664.GATA3.Kelly 194 bp overlap

GATA4 5 datasets

ChIP G296S GSE85628.GATA4.G296S 256 bp overlap

ChIP G296S_2 GSE85628.GATA4.G296S_2 256 bp overlap

ChIP G296S_4 GSE85628.GATA4.G296S_4 244 bp overlap

ChIP cardiomyocyte_5 GSE85628.GATA4.cardiomyocyte_5 327 bp overlap

ChIP cardiomyocyte_7 GSE85628.GATA4.cardiomyocyte_7 250 bp overlap

GRHL2 1 dataset

ChIP LNCaP GSE80256.GRHL2.LNCaP 203 bp overlap

GTF3C2 1 dataset

ChIP H9 GSE94418.GTF3C2.H9 279 bp overlap

HAND2 2 datasets

Motif DE_12h DE_12h-HAND2_MA1638.2 6 bp overlap

ChIP SK-N-BE2-C GSE94822.HAND2.SK-N-BE2-C 157 bp overlap

HDAC2 2 datasets

ChIP RH4_DMSO-6H GSE116344.HDAC2.RH4_DMSO-6H 501 bp overlap

ChIP RH4_Entinostat-6H GSE116344.HDAC2.RH4_Entinostat-6H 560 bp overlap

HDAC3 1 dataset

ChIP RH4_DMSO-6H GSE116344.HDAC3.RH4_DMSO-6H 646 bp overlap

HNRNPH1 2 datasets

ChIP Hep-G2 ENCSR066FXN.HNRNPH1.Hep-G2 216 bp overlap

ChIP Hep-G2 GSE120104.HNRNPH1.Hep-G2 216 bp overlap

Hand1 1 dataset

Motif DE_12h DE_12h-Hand1_MA2123.1 9 bp overlap

IRF2 1 dataset

ChIP keratinocyte_DOX GSE135677.IRF2.keratinocyte_DOX 117 bp overlap

JUN 1 dataset

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 181 bp overlap

KDM4C 1 dataset

ChIP KYSE-150 GSE53938.KDM4C.KYSE-150 242 bp overlap

LMO2 1 dataset

ChIP Kasumi-1_SICTR GSE60130.LMO2.Kasumi-1_SICTR 131 bp overlap

MAX 3 datasets

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 310 bp overlap

ChIP NCI-H2171 GSE41105.MAX.NCI-H2171 370 bp overlap

ChIP NCI-H2171 GSE36354.MAX.NCI-H2171 68 bp overlap

MED1 4 datasets

ChIP G296S GSE85628.MED1.G296S 461 bp overlap

ChIP G296S_2 GSE85628.MED1.G296S_2 461 bp overlap

ChIP cardiomyocyte_5 GSE85628.MED1.cardiomyocyte_5 400 bp overlap

ChIP cardiomyocyte_7 GSE85628.MED1.cardiomyocyte_7 326 bp overlap

MED26 1 dataset

ChIP HEK293T GSE121024.MED26.HEK293T 182 bp overlap

MEF2A 1 dataset

Motif DE_12h DE_12h-MEF2A_MA0052.5 10 bp overlap

MEF2B 1 dataset

Motif DE_12h DE_12h-MEF2B_MA0660.1 12 bp overlap

MEF2C 1 dataset

Motif DE_12h DE_12h-MEF2C_MA0497.2 11 bp overlap

MEF2D 1 dataset

Motif DE_12h DE_12h-MEF2D_MA0773.1 12 bp overlap

MRTFB 1 dataset

ChIP A-673-clone-Asp114 GSE92738.MRTFB.A-673-clone-Asp114 351 bp overlap

MTA2 1 dataset

ChIP RH4 GSE155861.MTA2.RH4 646 bp overlap

MYB 1 dataset

Motif DE_12h DE_12h-MYB_MA0100.4 6 bp overlap

MYBL2 1 dataset

ChIP A-673 GSE119971.MYBL2.A-673 196 bp overlap

MYCN 4 datasets

ChIP Kelly GSE94822.MYCN.Kelly 129 bp overlap

ChIP Kelly_sensitive GSE115249.MYCN.Kelly_sensitive 204 bp overlap

ChIP NB-1643 GSE138295.MYCN.NB-1643 312 bp overlap

ChIP RH4 GSE83726.MYCN.RH4 355 bp overlap

MYF6 1 dataset

Motif DE_12h DE_12h-MYF6_MA0667.1 10 bp overlap

MYOD1 2 datasets

ChIP RH30_DMSO GSE85169.MYOD1.RH30_DMSO 249 bp overlap

ChIP RH4 GSE83726.MYOD1.RH4 446 bp overlap

MYOG 1 dataset

ChIP RH4 GSE83726.MYOG.RH4 251 bp overlap

MZF1 1 dataset

ChIP HEK293 ENCSR298QUH.MZF1.HEK293 267 bp overlap

NANOG 1 dataset

ChIP LNCaP_pNanog8 GSE74799.NANOG.LNCaP_pNanog8 99 bp overlap

NCOR1 1 dataset

ChIP HEK293T_SICTR GSE35197.NCOR1.HEK293T_SICTR 205 bp overlap

NEUROD1 1 dataset

Motif DE_12h DE_12h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 1 dataset

Motif DE_12h DE_12h-NEUROG2_MA1642.2 7 bp overlap

NFIA 1 dataset

ChIP K-562 GSE97661.NFIA.K-562 502 bp overlap

NFIB 3 datasets

ChIP MCF-7 ENCFF925CGH 385 bp overlap

ChIP MCF-7 ENCSR702BYX.NFIB.MCF-7 233 bp overlap

ChIP MCF-7 ENCSR582ZOA.NFIB.MCF-7 300 bp overlap

NFIC 3 datasets

ChIP Ishikawa ENCSR000BUT.NFIC.Ishikawa 217 bp overlap

ChIP K-562 ENCSR796ITY.NFIC.K-562 603 bp overlap

ChIP K562 ENCFF167YID 538 bp overlap

NFIX 2 datasets

ChIP K-562 ENCSR574VJG.NFIX.K-562 319 bp overlap

ChIP K562 ENCFF382SJS 301 bp overlap

NOTCH3 1 dataset

ChIP TALL-1_GSI GSE104261.NOTCH3.TALL-1_GSI 239 bp overlap

NRIP1 1 dataset

ChIP MCF-7_E2 ERP005838.NRIP1.MCF-7_E2 145 bp overlap

Neurod2 1 dataset

Motif DE_12h DE_12h-Neurod2_MA0668.3 8 bp overlap

OLIG2 1 dataset

ChIP brain-prefrontal-cortex_2017014 GSE129039.OLIG2.brain-prefrontal-cortex_2017014 170 bp overlap

PAX3-FOXO1 1 dataset

ChIP RH4 GSE140115.PAX3-FOXO1.RH4 627 bp overlap

PHF19 1 dataset

ChIP DU145_SH4 GSE135623.PHF19.DU145_SH4 334 bp overlap

PLAG1 1 dataset

ChIP K-562 GSE111469.PLAG1.K-562 305 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 573 bp overlap

RAD21 2 datasets

ChIP RH4 GSE83726.RAD21.RH4 347 bp overlap

ChIP RH4 GSE83726.RAD21.RH4 184 bp overlap

RBBP4 3 datasets

ChIP RH5 GSE155861.RBBP4.RH5 317 bp overlap

ChIP RH5 GSE155861.RBBP4.RH5 188 bp overlap

ChIP SCMC GSE155861.RBBP4.SCMC 614 bp overlap

RBFOX2 1 dataset

ChIP K562 ENCFF196WTG 179 bp overlap

RELB 1 dataset

Motif DE_12h DE_12h-RELB_MA1117.2 7 bp overlap

REST 1 dataset

Motif DE_12h DE_12h-REST_MA0138.3 20 bp overlap

RFX1 4 datasets

ChIP K-562 ENCSR041AXL.RFX1.K-562 455 bp overlap

ChIP K-562 ENCSR968GIB.RFX1.K-562 466 bp overlap

ChIP K562 ENCFF421AVO 307 bp overlap

ChIP K562 ENCFF809XVG 315 bp overlap

SALL2 1 dataset

ChIP HEK293 GSE145940.SALL2.HEK293 133 bp overlap

SMAD2 1 dataset

Motif DE_12h DE_12h-SMAD2_MA1964.2 6 bp overlap

SMARCC1 1 dataset

ChIP SK-N-MC GSE94275.SMARCC1.SK-N-MC 203 bp overlap

T 1 dataset

ChIP H9_MESODERM GSE60606.T.H9_MESODERM 272 bp overlap

TBL1X 1 dataset

ChIP HEK293T GSE35197.TBL1X.HEK293T 198 bp overlap

TEAD2 1 dataset

Motif DE_12h DE_12h-TEAD2_MA1121.2 7 bp overlap

TEAD4 2 datasets

Motif DE_12h DE_12h-TEAD4_MA0809.3 8 bp overlap

ChIP hMSC-TERT4 GSE140782.TEAD4.hMSC-TERT4 332 bp overlap

TFAP4 1 dataset

ChIP K562 ENCFF727PXG 297 bp overlap

TP63 1 dataset

ChIP breast-organoid GSE113909.TP63.breast-organoid 127 bp overlap

TWIST1 3 datasets

ChIP BE2C GSE80151.TWIST1.BE2C 191 bp overlap

Motif DE_12h DE_12h-TWIST1_MA1123.3 8 bp overlap

ChIP SK-N-BE2-C GSE80151.TWIST1.SK-N-BE2-C 191 bp overlap

Tfcp2l1 1 dataset

Motif DE_12h DE_12h-Tfcp2l1_MA0145.2 14 bp overlap

Thap11 1 dataset

Motif DE_12h DE_12h-Thap11_MA1573.2 14 bp overlap

U2AF1 1 dataset

ChIP Hep-G2 GSE120104.U2AF1.Hep-G2 231 bp overlap

YAP1 2 datasets

ChIP hiPSC GSE111930.YAP1.hiPSC 170 bp overlap

ChIP hiPSC GSE111930.YAP1.hiPSC 156 bp overlap

YY1 1 dataset

ChIP RH4_DMSO-6H GSE116344.YY1.RH4_DMSO-6H 450 bp overlap

ZBTB12 1 dataset

Motif DE_12h DE_12h-ZBTB12_MA1649.2 7 bp overlap

ZBTB18 1 dataset

Motif DE_12h DE_12h-ZBTB18_MA0698.2 11 bp overlap

ZIC2 1 dataset

ChIP HEK293 ENCFF033NQQ 395 bp overlap

ZNF143 1 dataset

ChIP FLP143HA_T0 GSE39263.ZNF143.FLP143HA_T0 166 bp overlap

ZNF16 1 dataset

Motif DE_12h DE_12h-ZNF16_MA1654.2 21 bp overlap

ZNF213 1 dataset

Motif DE_12h DE_12h-ZNF213_MA2121.1 12 bp overlap

ZNF282 1 dataset

Motif DE_12h DE_12h-ZNF282_MA1154.2 15 bp overlap

ZNF3 1 dataset

ChIP K-562 ENCSR195QFV.ZNF3.K-562 276 bp overlap

ZNF572 1 dataset

ChIP Hep-G2 ENCSR663CTC.ZNF572.Hep-G2 274 bp overlap

ZNF582 1 dataset

Motif DE_12h DE_12h-ZNF582_MA1983.2 19 bp overlap

ZNF711 1 dataset

ChIP HEK293T GSE145160.ZNF711.HEK293T 382 bp overlap

ZNF891 1 dataset

ChIP Hep-G2 ENCSR020CLV.ZNF891.Hep-G2 351 bp overlap