chr18 : 21,754,780 – 21,755,646
866 bp 105 TFs 4 linked genes
This 866 bp open chromatin element is linked to 4 target genes and is bound by 105 transcription factors.
Linked Genes
4 genes
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
MIB1 50.3 kb Distal Multiome
ABHD3 50.4 kb Distal Multiome
SNRPD1 142.9 kb Distal Multiome
ESCO1 154.3 kb Distal Multiome
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr18:21,749,780 – 21,760,646
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
105 transcription factors
Source
Cell type
ARID1B 2 datasets
ChIP K-562 ENCSR822CCM.ARID1B.K-562 768 bp overlap
ChIP K562 ENCFF938UXQ 367 bp overlap
ATF7 1 dataset
ChIP K-562 ENCSR972ZBV.ATF7.K-562 263 bp overlap
BCL11A 2 datasets
ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 53 bp overlap
ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 53 bp overlap
BRD4 2 datasets
ChIP HEK293T GSE39579.BRD4.HEK293T 185 bp overlap
ChIP K-562 GSE140325.BRD4.K-562 158 bp overlap
BRD9 2 datasets
ChIP K-562 ENCSR177XCS.BRD9.K-562 270 bp overlap
ChIP K562 ENCFF480JXZ 451 bp overlap
CBFA2T2 2 datasets
ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 336 bp overlap
ChIP K562 ENCFF963TXY 381 bp overlap
CBFA2T3 3 datasets
ChIP K-562 GSE142227.CBFA2T3.K-562 326 bp overlap
ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 615 bp overlap
ChIP K562 ENCFF673OEZ 518 bp overlap
CCNT2 2 datasets
ChIP K-562 ENCSR000DOA.CCNT2.K-562 183 bp overlap
ChIP K562 ENCFF199GSZ 425 bp overlap
CEBPD 1 dataset
ChIP K-562 ENCSR000BVY.CEBPD.K-562 237 bp overlap
CREM 1 dataset
ChIP K-562 ENCSR077DKV.CREM.K-562 161 bp overlap
CTBP1 2 datasets
ChIP K-562 ENCSR201NQZ.CTBP1.K-562 548 bp overlap
ChIP K562 ENCFF403WPG 545 bp overlap
CXXC5 1 dataset
ChIP K562 ENCFF497CZN 146 bp overlap
DPF2 2 datasets
ChIP K-562 ENCSR219BXP.DPF2.K-562 204 bp overlap
ChIP K562 ENCFF775HUO 410 bp overlap
DRAP1 1 dataset
ChIP Hep-G2 ENCSR765MKZ.DRAP1.Hep-G2 247 bp overlap
ELF4 2 datasets
ChIP K-562 ENCSR638QHV.ELF4.K-562 261 bp overlap
ChIP K562 ENCFF454SBL 465 bp overlap
EOMES 1 dataset
ChIP hESC GSE26097.EOMES.hESC 277 bp overlap
EP300 2 datasets
ChIP K-562 ENCSR000EGE.EP300.K-562 248 bp overlap
ChIP K562 ENCFF226VMS 317 bp overlap
ERG 1 dataset
ChIP VCaP_shARID1A GSE110655.ERG.VCaP_shARID1A 207 bp overlap
FOXA1 9 datasets
ChIP HepG2 ENCFF207NVJ 281 bp overlap
ChIP HepG2 ENCFF740VZW 285 bp overlap
ChIP MCF-7 GSE81714.FOXA1.MCF-7 250 bp overlap
ChIP MCF-7 ERP000380.FOXA1.MCF-7 163 bp overlap
ChIP MCF-7_E2 GSE60270.FOXA1.MCF-7_E2 260 bp overlap
ChIP MCF-7_E2 GSE23852.FOXA1.MCF-7_E2 154 bp overlap
ChIP MCF-7_estrogen_ab2 GSE112969.FOXA1.MCF-7_estrogen_ab2 381 bp overlap
ChIP MCF-7_vehicle_ab2 GSE112969.FOXA1.MCF-7_vehicle_ab2 290 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA1.pancreatic-progenitor_PP1 411 bp overlap
FOXA2 7 datasets
ChIP BJ1-hTERT_MimoRelease GSE92491.FOXA2.BJ1-hTERT_MimoRelease 372 bp overlap
ChIP Caco-2 GSE66218.FOXA2.Caco-2 170 bp overlap
ChIP DE DE-FOXA2-1 820 bp overlap
ChIP DE DE-FOXA2-2 866 bp overlap
ChIP HepG2 ENCFF533COJ 297 bp overlap
ChIP KerCT GSE90454.FOXA2.KerCT 237 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.FOXA2.pancreatic-progenitor_PP1 477 bp overlap
FOXA3 1 dataset
ChIP K562 ENCFF781VSC 341 bp overlap
FOXK2 4 datasets
ChIP K-562 ENCSR302AWT.FOXK2.K-562 290 bp overlap
ChIP K-562 ENCSR508DQA.FOXK2.K-562 321 bp overlap
ChIP K562 ENCFF245WKP 142 bp overlap
ChIP K562 ENCFF851PFH 211 bp overlap
FOXL2 4 datasets
ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 199 bp overlap
ChIP HGrC1_C134W-TGF_parental GSE138496.FOXL2.HGrC1_C134W-TGF_parental 166 bp overlap
ChIP KGN_1512 GSE138496.FOXL2.KGN_1512 372 bp overlap
ChIP KGN_1513 GSE138496.FOXL2.KGN_1513 355 bp overlap
FOXP1 1 dataset
ChIP Hep-G2 ENCSR369YUK.FOXP1.Hep-G2 178 bp overlap
GATA1 12 datasets
ChIP CD34_Day7_30min GSE104676.GATA1.CD34_Day7_30min 103 bp overlap
ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 305 bp overlap
ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 264 bp overlap
Motif DE_60h DE_60h-GATA1_MA0035.5 7 bp overlap
ChIP HUDEP-2_30min GSE104676.GATA1.HUDEP-2_30min 64 bp overlap
ChIP K-562 GSE107726.GATA1.K-562 632 bp overlap
ChIP K-562 ENCSR000EFT.GATA1.K-562 180 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 335 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.GATA1.K-562_enCRISPRi-LK 326 bp overlap
ChIP K562 ENCFF094CMK 251 bp overlap
ChIP erythroblast ENCFF867JAR 407 bp overlap
ChIP erythroblast ENCSR000EXP.GATA1.erythroblast 564 bp overlap
GATA1::TAL1 1 dataset
Motif DE_60h DE_60h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 8 datasets
ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 103 bp overlap
ChIP CD34_ACY957 GSE60792.GATA2.CD34_ACY957 265 bp overlap
ChIP K-562 ENCSR000DKA.GATA2.K-562 478 bp overlap
ChIP K-562 ENCSR000BKM.GATA2.K-562 114 bp overlap
ChIP K562 ENCFF544PCK 251 bp overlap
ChIP K562 ENCFF830LLA 577 bp overlap
ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 215 bp overlap
ChIP TF1 GSE73207.GATA2.TF1 563 bp overlap
GATA3 1 dataset
ChIP MCF-7_E2 GSE81510.GATA3.MCF-7_E2 158 bp overlap
GATA4 6 datasets
ChIP A-549 GSE85002.GATA4.A-549 166 bp overlap
ChIP DE DE-GATA4-1 866 bp overlap
ChIP DE DE-GATA4-2 866 bp overlap
ChIP Hep-G2 GSE135714.GATA4.Hep-G2 548 bp overlap
ChIP foregut GSE117136.GATA4.foregut 711 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 866 bp overlap
GATA6 13 datasets
ChIP AGS GSE51705.GATA6.AGS 268 bp overlap
ChIP DE DE-GATA6-1 843 bp overlap
ChIP DE DE-GATA6-2 866 bp overlap
Motif DE_60h DE_60h-GATA6_MA1104.3 8 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 678 bp overlap
ChIP HUG1N GSE51936.GATA6.HUG1N 270 bp overlap
ChIP PATU8988 GSE47535.GATA6.PATU8988 168 bp overlap
ChIP YCC-3 GSE51705.GATA6.YCC-3 205 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 655 bp overlap
ChIP foregut GSE117136.GATA6.foregut 633 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 733 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 450 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 756 bp overlap
GATAD2A 1 dataset
ChIP K562 ENCFF071LJW 345 bp overlap
GRHL1 1 dataset
Motif DE_60h DE_60h-GRHL1_MA0647.2 10 bp overlap
GRHL2 3 datasets
Motif DE_60h DE_60h-GRHL2_MA1105.3 8 bp overlap
ChIP HBE GSE46194.GRHL2.HBE 228 bp overlap
ChIP MCF-7 GSE109820.GRHL2.MCF-7 163 bp overlap
Gata3 1 dataset
Motif DE_60h DE_60h-Gata3_MA0037.5 8 bp overlap
Gmeb1 1 dataset
Motif DE_60h DE_60h-Gmeb1_MA0615.2 6 bp overlap
HDAC1 5 datasets
ChIP K-562 ENCSR387UWP.HDAC1.K-562 569 bp overlap
ChIP K-562 ENCSR711VWL.HDAC1.K-562 240 bp overlap
ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 105 bp overlap
ChIP K-562_dilution-6-100 GSE140325.HDAC1.K-562_dilution-6-100 140 bp overlap
ChIP K562 ENCFF968WBH 192 bp overlap
HDAC2 2 datasets
ChIP K-562 ENCSR893WSB.HDAC2.K-562 614 bp overlap
ChIP K562 ENCFF744ALD 421 bp overlap
HMBOX1 2 datasets
ChIP K562 ENCFF055GAZ 716 bp overlap
ChIP K562 ENCFF317JJX 681 bp overlap
HMGN3 2 datasets
ChIP K-562 ENCSR000DOB.HMGN3.K-562 169 bp overlap
ChIP K562 ENCFF083BIJ 465 bp overlap
IKZF1 1 dataset
ChIP K-562 ENCSR395HWC.IKZF1.K-562 494 bp overlap
ILF3 1 dataset
ChIP K-562 GSE103215.ILF3.K-562 89 bp overlap
IRF2 1 dataset
Motif DE_60h DE_60h-IRF2_MA0051.2 16 bp overlap
IRF6 1 dataset
Motif DE_60h DE_60h-IRF6_MA1509.1 9 bp overlap
IRF9 1 dataset
Motif DE_60h DE_60h-IRF9_MA0653.1 15 bp overlap
KDM1A 8 datasets
ChIP K-562 ENCSR908CMW.KDM1A.K-562 59 bp overlap
ChIP K-562 GSE117944.KDM1A.K-562 529 bp overlap
ChIP K-562 ENCSR000ATX.KDM1A.K-562 673 bp overlap
ChIP K-562 ENCSR908CMW.KDM1A.K-562 269 bp overlap
ChIP K-562_Wnt GSE117944.KDM1A.K-562_Wnt 202 bp overlap
ChIP K562 ENCFF128TYE 445 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.KDM1A.pancreatic-progenitor_PP1 313 bp overlap
ChIP pancreatic-progenitor_PP2-KDM1A-inh GSE104840.KDM1A.pancreatic-progenitor_PP2-KDM1A-inh 283 bp overlap
KLF1 1 dataset
ChIP erythroid_R3R4 GSE43625.KLF1.erythroid_R3R4 61 bp overlap
KLF16 1 dataset
ChIP K-562 ENCSR760UVO.KLF16.K-562 126 bp overlap
LDB1 1 dataset
ChIP K-562 GSE142227.LDB1.K-562 367 bp overlap
LMO2 1 dataset
ChIP TSU-1621MT GSE60477.LMO2.TSU-1621MT 179 bp overlap
MEIS1 1 dataset
Motif DE_60h DE_60h-MEIS1_MA0498.3 5 bp overlap
MEIS2 1 dataset
ChIP K-562 ENCSR851BNE.MEIS2.K-562 215 bp overlap
MLLT1 1 dataset
ChIP K-562 ENCSR107GRP.MLLT1.K-562 325 bp overlap
MTA1 1 dataset
ChIP K-562 ENCSR807BGP.MTA1.K-562 220 bp overlap
MTA3 1 dataset
ChIP K-562 ENCSR180NCY.MTA3.K-562 329 bp overlap
MYB 1 dataset
ChIP DU528 GSE94000.MYB.DU528 489 bp overlap
MYBL2 2 datasets
ChIP A-673 GSE119971.MYBL2.A-673 331 bp overlap
ChIP A-673 GSE119971.MYBL2.A-673 160 bp overlap
NBN 1 dataset
ChIP K-562 ENCSR085QEV.NBN.K-562 344 bp overlap
NCOR1 4 datasets
ChIP K-562 ENCSR798ILC.NCOR1.K-562 426 bp overlap
ChIP K-562 ENCSR910JAI.NCOR1.K-562 238 bp overlap
ChIP K562 ENCFF788MPU 421 bp overlap
ChIP K562 ENCFF866HRM 445 bp overlap
NR3C1 1 dataset
ChIP K-562_GLUCC ERP007081.NR3C1.K-562_GLUCC 101 bp overlap
PRDM10 1 dataset
ChIP K562 ENCFF740YLK 417 bp overlap
Pgr 1 dataset
Motif DE_60h DE_60h-Pgr_MA2323.1 17 bp overlap
REST 1 dataset
ChIP K-562 GSE70482.REST.K-562 153 bp overlap
RNF2 1 dataset
ChIP K562 ENCFF653BQJ 611 bp overlap
SCRT1 1 dataset
ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 272 bp overlap
SETDB1 2 datasets
ChIP HEK293 ENCSR348AGV.SETDB1.HEK293 419 bp overlap
ChIP U2OS ENCSR000EYD.SETDB1.U2OS 420 bp overlap
SMAD2 1 dataset
ChIP endoderm GSE29422.SMAD2.endoderm 236 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 709 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 471 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 517 bp overlap
SMAD4 1 dataset
ChIP Caco-2 GSE112946.SMAD4.Caco-2 262 bp overlap
SMARCA4 3 datasets
ChIP CTV-1_delQ GSE128835.SMARCA4.CTV-1_delQ 273 bp overlap
ChIP K-562 ENCSR587OQL.SMARCA4.K-562 575 bp overlap
ChIP K-562 ENCSR643VTW.SMARCA4.K-562 229 bp overlap
SMARCA5 2 datasets
ChIP K-562 ENCSR895HSJ.SMARCA5.K-562 294 bp overlap
ChIP K562 ENCFF936KHY 417 bp overlap
SMARCE1 2 datasets
ChIP K-562 ENCSR157TCS.SMARCE1.K-562 522 bp overlap
ChIP K562 ENCFF690CFF 517 bp overlap
SNAI2 1 dataset
ChIP keratinocyte_LacZ GSE55421.SNAI2.keratinocyte_LacZ 210 bp overlap
SOX10 1 dataset
Motif DE_60h DE_60h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 778 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 691 bp overlap
SOX6 2 datasets
ChIP K-562 ENCSR788RSW.SOX6.K-562 605 bp overlap
ChIP K562 ENCFF059YCJ 349 bp overlap
SPI1 5 datasets
ChIP CTV-1_FLAG_15perc GSE128835.SPI1.CTV-1_FLAG_15perc 380 bp overlap
ChIP CTV-1_delQ GSE128835.SPI1.CTV-1_delQ 274 bp overlap
ChIP K-562 GSE70482.SPI1.K-562 179 bp overlap
ChIP K-562_NABUT GSE74999.SPI1.K-562_NABUT 110 bp overlap
ChIP Kasumi-1_SIRUNX1ETO GSE60130.SPI1.Kasumi-1_SIRUNX1ETO 175 bp overlap
STAT1 1 dataset
ChIP SET-2_DMSO GSE100566.STAT1.SET-2_DMSO 336 bp overlap
STAT1_pS727 1 dataset
ChIP SET-2 GSE100566.STAT1_pS727.SET-2 406 bp overlap
STAT5A 1 dataset
ChIP K-562 ENCSR000BRR.STAT5A.K-562 128 bp overlap
Six3 1 dataset
Motif DE_60h DE_60h-Six3_MA0631.2 11 bp overlap
Stat6 1 dataset
Motif DE_60h DE_60h-Stat6_MA0520.2 10 bp overlap
TAL1 11 datasets
ChIP CD34 GSE52924.TAL1.CD34 147 bp overlap
ChIP CHRF28811 ERP008568.TAL1.CHRF28811 555 bp overlap
ChIP K-562 GSE107726.TAL1.K-562 799 bp overlap
ChIP K-562 ENCSR106FRG.TAL1.K-562 292 bp overlap
ChIP K-562 ENCSR000EHB.TAL1.K-562 146 bp overlap
ChIP K-562_dCas9-KRAB GSE132212.TAL1.K-562_dCas9-KRAB 177 bp overlap
ChIP K-562_dCas9-LSD1 GSE132212.TAL1.K-562_dCas9-LSD1 365 bp overlap
ChIP K-562_enCRISPRi-KL GSE132212.TAL1.K-562_enCRISPRi-KL 405 bp overlap
ChIP K-562_enCRISPRi-LK GSE132212.TAL1.K-562_enCRISPRi-LK 411 bp overlap
ChIP K562 ENCFF620GMX 385 bp overlap
ChIP K562 ENCFF661CCK 277 bp overlap
TBL1XR1 1 dataset
ChIP K-562 ENCSR000EGB.TBL1XR1.K-562 213 bp overlap
TCF12 4 datasets
ChIP K-562 ENCSR189TRZ.TCF12.K-562 299 bp overlap
ChIP K-562 ENCSR744WOO.TCF12.K-562 438 bp overlap
ChIP K562 ENCFF909RDY 397 bp overlap
ChIP K562 ENCFF931DJY 391 bp overlap
TCF3 1 dataset
ChIP K-562 ENCSR970OJY.TCF3.K-562 196 bp overlap
TEAD4 1 dataset
ChIP K562 ENCFF673NIK 365 bp overlap
THRB 1 dataset
ChIP K562 ENCFF620NFN 291 bp overlap
TP53 1 dataset
ChIP K-562_R282W_Daunorubicin GSE131484.TP53.K-562_R282W_Daunorubicin 340 bp overlap
TP63 4 datasets
ChIP keratinocyte GSE33571.TP63.keratinocyte 134 bp overlap
ChIP keratinocyte_D0 GSE59824.TP63.keratinocyte_D0 297 bp overlap
ChIP keratinocyte_D2 GSE59824.TP63.keratinocyte_D2 282 bp overlap
ChIP keratinocyte_D7 GSE59824.TP63.keratinocyte_D7 172 bp overlap
TRIM24 1 dataset
ChIP K562 ENCFF616RIL 451 bp overlap
TRPS1 1 dataset
Motif DE_60h DE_60h-TRPS1_MA1970.2 8 bp overlap
YY1 1 dataset
ChIP Hep-G2_RBM25-KD GSE120104.YY1.Hep-G2_RBM25-KD 265 bp overlap
ZBTB32 1 dataset
Motif DE_60h DE_60h-ZBTB32_MA1580.1 10 bp overlap
ZBTB7A 3 datasets
ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 422 bp overlap
ChIP Hep-G2 ENCSR000BQA.ZBTB7A.Hep-G2 119 bp overlap
ChIP K-562 GSE103445.ZBTB7A.K-562 425 bp overlap
ZEB2 2 datasets
ChIP K-562 ENCSR004GKA.ZEB2.K-562 472 bp overlap
ChIP K-562 ENCSR322CFO.ZEB2.K-562 269 bp overlap
ZIM3 1 dataset
ChIP HEK293 GSE76494.ZIM3.HEK293 106 bp overlap
ZNF281 1 dataset
ChIP K562 ENCFF594VNM 471 bp overlap
ZNF311 2 datasets
ChIP K-562 ENCSR388ZRV.ZNF311.K-562 240 bp overlap
ChIP K562 ENCFF986QSP 365 bp overlap
ZNF337 1 dataset
ChIP HEK293T GSE78099.ZNF337.HEK293T 330 bp overlap
ZNF384 4 datasets
ChIP HEK293T ENCFF019DZX 391 bp overlap
ChIP HEK293T ENCSR882ICT.ZNF384.HEK293T 247 bp overlap
ChIP K-562 ENCSR000EFP.ZNF384.K-562 426 bp overlap
ChIP K562 ENCFF365NXQ 297 bp overlap
ZNF652 2 datasets
ChIP Hep-G2 ENCSR502GAX.ZNF652.Hep-G2 269 bp overlap
ChIP HepG2 ENCFF331VPZ 381 bp overlap
ZNF766 1 dataset
ChIP K562 ENCFF348LDO 250 bp overlap
ZXDB 1 dataset
ChIP HEK293 ENCSR559IOZ.ZXDB.HEK293 264 bp overlap
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