chr17:58,527,884–58,528,411

chr17 : 58,527,884 – 58,528,411

527 bp 79 TFs 9 linked genes

This 527 bp open chromatin element is linked to 9 target genes and is bound by 79 transcription factors.

Linked Genes

9 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SEPTIN4		at TSS	At TSS	Proximity
ENSG00000289147		9.6 kb	Proximal	Proximity
MTMR4		10.3 kb	Distal	Multiome
TEX14		36.1 kb	Distal	Multiome
RNF43		110.6 kb	Distal	Multiome
RAD51C		164.4 kb	Distal	Multiome
SUPT4H1		176.0 kb	Distal	Multiome
TSPOAP1		199.4 kb	Distal	Multiome
PPM1E		227.7 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

79 transcription factors

ChIP THP-1_R1881 GSE131381.AR.THP-1_R1881 211 bp overlap

ARID1A 2 datasets

ChIP 12Z GSE129781.ARID1A.12Z 212 bp overlap

ChIP endometrial-epithelial-cells GSE106660.ARID1A.endometrial-epithelial-cells 265 bp overlap

BCL11A 4 datasets

ChIP CD34_Day3_30min GSE104676.BCL11A.CD34_Day3_30min 105 bp overlap

ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 63 bp overlap

ChIP CD34_Day7_30min GSE104676.BCL11A.CD34_Day7_30min 75 bp overlap

ChIP HUDEP-2_90min GSE104676.BCL11A.HUDEP-2_90min 68 bp overlap

BHLHE40 6 datasets

ChIP GM12878 ENCFF521IZR 228 bp overlap

ChIP GM12878 ENCSR987MTA.BHLHE40.GM12878 382 bp overlap

ChIP GM12878 ENCSR517QHU.BHLHE40.GM12878 356 bp overlap

ChIP Hep-G2 ENCSR000EDT.BHLHE40.Hep-G2 120 bp overlap

ChIP IMR-90 ENCFF312JYK 285 bp overlap

ChIP IMR-90 ENCSR957KYB.BHLHE40.IMR-90 181 bp overlap

BRCA1 1 dataset

ChIP SH-EP_pWZL-MYCNwt GSE111905.BRCA1.SH-EP_pWZL-MYCNwt 95 bp overlap

BRD4 4 datasets

ChIP COLO-741 GSE73319.BRD4.COLO-741 181 bp overlap

ChIP HCC1395 GSE63581.BRD4.HCC1395 392 bp overlap

ChIP K-562_DMSO-IFNG GSE138084.BRD4.K-562_DMSO-IFNG 240 bp overlap

ChIP SUM159PT_scramble GSE131097.BRD4.SUM159PT_scramble 270 bp overlap

CBFA2T2 2 datasets

ChIP K-562 ENCSR699PVC.CBFA2T2.K-562 255 bp overlap

ChIP K562 ENCFF963TXY 357 bp overlap

CBFA2T3 2 datasets

ChIP K-562 ENCSR697YLJ.CBFA2T3.K-562 288 bp overlap

ChIP K562 ENCFF673OEZ 131 bp overlap

ChIP SET-2 GSE65138.CDK8.SET-2 195 bp overlap

CDKN1B 1 dataset

ChIP MDA-MB-231 GSE112444.CDKN1B.MDA-MB-231 221 bp overlap

CTBP1 1 dataset

ChIP K-562 ENCSR201NQZ.CTBP1.K-562 423 bp overlap

CTCF 9 datasets

ChIP CD14-positive monocyte ENCFF087XLR 217 bp overlap

ChIP DOHH2 ENCFF637WNW 87 bp overlap

ChIP K562 ENCFF430KTH 75 bp overlap

ChIP OCI-LY7 ENCFF086AXQ 65 bp overlap

ChIP SU-DHL-6 ENCFF116KKR 151 bp overlap

ChIP SUM159 GSE46055.CTCF.SUM159 131 bp overlap

ChIP dorsolateral prefrontal cortex ENCFF442YDO 391 bp overlap

ChIP epithelial cell of prostate ENCFF086GTI 116 bp overlap

ChIP lymphoblast_mut GSE155324.CTCF.lymphoblast_mut 138 bp overlap

ChIP GM12878 ENCSR509FWH.DPF2.GM12878 501 bp overlap

ChIP GM12878 ENCSR439WAF.E4F1.GM12878 198 bp overlap

ChIP GM12878 ENCFF167CZS 321 bp overlap

ChIP PDAC_KOKLF5 GSE64557.ELF3.PDAC_KOKLF5 96 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 149 bp overlap

ChIP TSU-1621MT GSE60477.ERG.TSU-1621MT 215 bp overlap

ChIP TSU-1621MT_ATRA GSE60477.ERG.TSU-1621MT_ATRA 224 bp overlap

ESR1 2 datasets

ChIP MCF-7_PaPE-1 GSE93510.ESR1.MCF-7_PaPE-1 170 bp overlap

ChIP MCF-7_PaPE-1_OA GSE93510.ESR1.MCF-7_PaPE-1_OA 214 bp overlap

ChIP HUVEC-C_VEGF_12H GSE41166.ETS1.HUVEC-C_VEGF_12H 360 bp overlap

ChIP COLO-800 GSE80443.ETV1.COLO-800 202 bp overlap

ChIP LNCaP GSE39459.EZH2.LNCaP 112 bp overlap

ChIP CFPAC-1 GSE119930.FOS.CFPAC-1 422 bp overlap

ChIP IMR-90 ENCSR124AIG.FOS.IMR-90 190 bp overlap

ChIP endothelial cell of umbilical vein ENCFF415XBG 401 bp overlap

ChIP endothelial_umbilical-vein ENCSR000EVU.FOS.endothelial_umbilical-vein 287 bp overlap

FOSL1 1 dataset

ChIP K-562 ENCSR239ZLZ.FOSL1.K-562 259 bp overlap

FOSL2 2 datasets

ChIP LPS141 GSE111253.FOSL2.LPS141 213 bp overlap

ChIP SK-N-SH ENCSR000BVB.FOSL2.SK-N-SH 136 bp overlap

FOXL2 1 dataset

ChIP HGrC1_C134W-TGF GSE138496.FOXL2.HGrC1_C134W-TGF 194 bp overlap

FOXO1 1 dataset

ChIP CD34 GSE80773.FOXO1.CD34 310 bp overlap

GATA1 3 datasets

ChIP CD34_ERYTH_BMP GSE29194.GATA1.CD34_ERYTH_BMP 112 bp overlap

ChIP K-562 GSE107726.GATA1.K-562 201 bp overlap

ChIP K-562_dCas9-LSD1 GSE132212.GATA1.K-562_dCas9-LSD1 157 bp overlap

GATA2 2 datasets

ChIP ME-1_CBFB-MYH11-KD GSE117138.GATA2.ME-1_CBFB-MYH11-KD 346 bp overlap

ChIP TF1 GSE73207.GATA2.TF1 294 bp overlap

GATA4 2 datasets

ChIP DE DE-GATA4-1 440 bp overlap

ChIP DE DE-GATA4-2 511 bp overlap

GATA6 10 datasets

ChIP DE DE-GATA6-1 460 bp overlap

ChIP DE DE-GATA6-2 416 bp overlap

ChIP DE_D1 S09-DE-d1-GATA6-exp1 445 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 450 bp overlap

ChIP DE_D1 S41-DE-d1-GATA6-exp2 347 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 511 bp overlap

ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 464 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 441 bp overlap

ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 464 bp overlap

ChIP foregut GSE117136.GATA6.foregut 382 bp overlap

GLIS1 1 dataset

ChIP HEK293 ENCSR482BBZ.GLIS1.HEK293 402 bp overlap

GLIS2 4 datasets

ChIP HCT-116_5FU GSE125927.GLIS2.HCT-116_5FU 249 bp overlap

ChIP HEK293 ENCFF446EIF 301 bp overlap

ChIP HEK293 ENCFF446EIF 511 bp overlap

ChIP HEK293 ENCSR535DIA.GLIS2.HEK293 349 bp overlap

GLIS3 1 dataset

ChIP H9_plus GSE109562.GLIS3.H9_plus 417 bp overlap

HDAC2 1 dataset

ChIP RH4_DMSO-6H_bioMerck GSE116344.HDAC2.RH4_DMSO-6H_bioMerck 158 bp overlap

IKZF1 2 datasets

ChIP GM12878 ENCFF753XDO 510 bp overlap

ChIP GM12878 ENCFF824TGK 527 bp overlap

ChIP 786-O GSE86092.JUN.786-O 190 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 428 bp overlap

ChIP HAEC_IL1b_4h GSE89970.JUN.HAEC_IL1b_4h 209 bp overlap

ChIP HAEC_TNFa_4h GSE89970.JUN.HAEC_TNFa_4h 198 bp overlap

ChIP HUVEC-C GSE109625.JUN.HUVEC-C 184 bp overlap

ChIP MCF10A-Er-Src_EtOH GSE115597.JUN.MCF10A-Er-Src_EtOH 130 bp overlap

ChIP MDA-BoM-1833 GSE112444.JUN.MDA-BoM-1833 206 bp overlap

ChIP MDA-MB-231 GSE112444.JUN.MDA-MB-231 209 bp overlap

JUNB 2 datasets

ChIP CFPAC-1 GSE119930.JUNB.CFPAC-1 320 bp overlap

ChIP HAEC GSE89970.JUNB.HAEC 153 bp overlap

ChIP K-562 ENCSR000EGN.JUND.K-562 164 bp overlap

ChIP PDAC GSE64557.KLF4.PDAC 126 bp overlap

LARP7 1 dataset

ChIP GM12878 ENCFF513CEX 441 bp overlap

ChIP TSU-1621MT GSE60477.LMO2.TSU-1621MT 336 bp overlap

ChIP TSU-1621MT GSE60477.LYL1.TSU-1621MT 237 bp overlap

ChIP SK-N-SH ENCSR000BVD.MAX.SK-N-SH 149 bp overlap

ChIP endothelial cell of umbilical vein ENCFF100YIN 241 bp overlap

ChIP endothelial_umbilical-vein ENCSR000EEZ.MAX.endothelial_umbilical-vein 132 bp overlap

MED1 5 datasets

ChIP HCT-116 GSE121798.MED1.HCT-116 169 bp overlap

ChIP HCT-116_shLuc GSE121798.MED1.HCT-116_shLuc 311 bp overlap

ChIP HCT-116_shLuc_thaps GSE121798.MED1.HCT-116_shLuc_thaps 198 bp overlap

ChIP HUVEC-C_siCTL GSE124892.MED1.HUVEC-C_siCTL 334 bp overlap

ChIP HUVEC-C_siERG GSE124892.MED1.HUVEC-C_siERG 171 bp overlap

ChIP A-549_MGA-OE GSE112188.MGA.A-549_MGA-OE 279 bp overlap

ChIP A-549_empty GSE112188.MGA.A-549_empty 346 bp overlap

ChIP GM12878 ENCSR293QAR.MTA2.GM12878 480 bp overlap

ChIP HT-1080 GSE86504.MYC.HT-1080 307 bp overlap

ChIP MCF-10A ENCSR000DOS.MYC.MCF-10A 212 bp overlap

ChIP U2OS_SHRCTR GSE77356.MYC.U2OS_SHRCTR 94 bp overlap

ChIP endothelial_umbilical-vein ENCSR000DLU.MYC.endothelial_umbilical-vein 78 bp overlap

NELFE 1 dataset

ChIP K-562_NHS GSE112379.NELFE.K-562_NHS 82 bp overlap

NFKB1 2 datasets

ChIP HEK293T GSE129618.NFKB1.HEK293T 99 bp overlap

ChIP L1236 GSE63736.NFKB1.L1236 126 bp overlap

NR3C1 5 datasets

ChIP BEAS-2B_DEX_IA1 GSE125623.NR3C1.BEAS-2B_DEX_IA1 337 bp overlap

ChIP BEAS-2B_TNF-DEX_IA1 GSE125623.NR3C1.BEAS-2B_TNF-DEX_IA1 426 bp overlap

ChIP BEAS-2B_TNF_IA1 GSE125623.NR3C1.BEAS-2B_TNF_IA1 527 bp overlap

ChIP BEAS-2B_Veh_IA1 GSE125623.NR3C1.BEAS-2B_Veh_IA1 383 bp overlap

ChIP BEAS-2B_shNR3C1_TNF_IA1 GSE125623.NR3C1.BEAS-2B_shNR3C1_TNF_IA1 418 bp overlap

RAD51 1 dataset

ChIP GM12878 ENCSR482TWQ.RAD51.GM12878 407 bp overlap

RELA 39 datasets

ChIP 786-O GSE86092.RELA.786-O 382 bp overlap

ChIP Detroit-562_Poly-I GSE91018.RELA.Detroit-562_Poly-I 302 bp overlap

ChIP HAEC GSE89970.RELA.HAEC 156 bp overlap

ChIP HAEC_IL1b_4h GSE89970.RELA.HAEC_IL1b_4h 297 bp overlap

ChIP HAEC_TNFa_4h GSE89970.RELA.HAEC_TNFa_4h 395 bp overlap

ChIP HUVEC-C_TNF GSE53998.RELA.HUVEC-C_TNF 378 bp overlap

ChIP HUVEC-C_TNF-30min GSE121890.RELA.HUVEC-C_TNF-30min 216 bp overlap

ChIP HUVEC-C_TNF-60min GSE121890.RELA.HUVEC-C_TNF-60min 293 bp overlap

ChIP HUVEC-C_TNF_30M GSE34500.RELA.HUVEC-C_TNF_30M 216 bp overlap

ChIP HUVEC-C_TNF_JQ1 GSE53998.RELA.HUVEC-C_TNF_JQ1 257 bp overlap

ChIP aortic-endothelial-cell_IL1B_D10 GSE139377.RELA.aortic-endothelial-cell_IL1B_D10 325 bp overlap

ChIP aortic-endothelial-cell_IL1B_D11 GSE139377.RELA.aortic-endothelial-cell_IL1B_D11 350 bp overlap

ChIP aortic-endothelial-cell_IL1B_D13 GSE139377.RELA.aortic-endothelial-cell_IL1B_D13 390 bp overlap

ChIP aortic-endothelial-cell_IL1B_D14 GSE139377.RELA.aortic-endothelial-cell_IL1B_D14 364 bp overlap

ChIP aortic-endothelial-cell_IL1B_D16 GSE139377.RELA.aortic-endothelial-cell_IL1B_D16 389 bp overlap

ChIP aortic-endothelial-cell_IL1B_D2 GSE139377.RELA.aortic-endothelial-cell_IL1B_D2 323 bp overlap

ChIP aortic-endothelial-cell_IL1B_D21 GSE139377.RELA.aortic-endothelial-cell_IL1B_D21 421 bp overlap

ChIP aortic-endothelial-cell_IL1B_D22 GSE139377.RELA.aortic-endothelial-cell_IL1B_D22 340 bp overlap

ChIP aortic-endothelial-cell_IL1B_D24 GSE139377.RELA.aortic-endothelial-cell_IL1B_D24 185 bp overlap

ChIP aortic-endothelial-cell_IL1B_D25 GSE139377.RELA.aortic-endothelial-cell_IL1B_D25 275 bp overlap

ChIP aortic-endothelial-cell_IL1B_D26 GSE139377.RELA.aortic-endothelial-cell_IL1B_D26 399 bp overlap

ChIP aortic-endothelial-cell_IL1B_D27 GSE139377.RELA.aortic-endothelial-cell_IL1B_D27 354 bp overlap

ChIP aortic-endothelial-cell_IL1B_D28 GSE139377.RELA.aortic-endothelial-cell_IL1B_D28 235 bp overlap

ChIP aortic-endothelial-cell_IL1B_D3 GSE139377.RELA.aortic-endothelial-cell_IL1B_D3 402 bp overlap

ChIP aortic-endothelial-cell_IL1B_D31 GSE139377.RELA.aortic-endothelial-cell_IL1B_D31 254 bp overlap

ChIP aortic-endothelial-cell_IL1B_D33 GSE139377.RELA.aortic-endothelial-cell_IL1B_D33 170 bp overlap

ChIP aortic-endothelial-cell_IL1B_D35 GSE139377.RELA.aortic-endothelial-cell_IL1B_D35 270 bp overlap

ChIP aortic-endothelial-cell_IL1B_D38 GSE139377.RELA.aortic-endothelial-cell_IL1B_D38 348 bp overlap

ChIP aortic-endothelial-cell_IL1B_D39 GSE139377.RELA.aortic-endothelial-cell_IL1B_D39 525 bp overlap

ChIP aortic-endothelial-cell_IL1B_D4 GSE139377.RELA.aortic-endothelial-cell_IL1B_D4 357 bp overlap

ChIP aortic-endothelial-cell_IL1B_D40 GSE139377.RELA.aortic-endothelial-cell_IL1B_D40 346 bp overlap

ChIP aortic-endothelial-cell_IL1B_D41 GSE139377.RELA.aortic-endothelial-cell_IL1B_D41 210 bp overlap

ChIP aortic-endothelial-cell_IL1B_D45 GSE139377.RELA.aortic-endothelial-cell_IL1B_D45 207 bp overlap

ChIP aortic-endothelial-cell_IL1B_D47 GSE139377.RELA.aortic-endothelial-cell_IL1B_D47 292 bp overlap

ChIP aortic-endothelial-cell_IL1B_D53 GSE139377.RELA.aortic-endothelial-cell_IL1B_D53 215 bp overlap

ChIP aortic-endothelial-cell_IL1B_D6 GSE139377.RELA.aortic-endothelial-cell_IL1B_D6 224 bp overlap

ChIP aortic-endothelial-cell_IL1B_D7 GSE139377.RELA.aortic-endothelial-cell_IL1B_D7 294 bp overlap

ChIP aortic-endothelial-cell_IL1B_D8 GSE139377.RELA.aortic-endothelial-cell_IL1B_D8 399 bp overlap

ChIP aortic-endothelial-cell_IL1B_D9 GSE139377.RELA.aortic-endothelial-cell_IL1B_D9 379 bp overlap

ChIP hippocampus GSE144226.REST.hippocampus 321 bp overlap

ChIP K-562 ENCSR138FUZ.RNF2.K-562 57 bp overlap

RUNX1T1 2 datasets

ChIP Kasumi-1 GSE115115.RUNX1T1.Kasumi-1 314 bp overlap

ChIP Kasumi-1_shTAF1-AE GSE115115.RUNX1T1.Kasumi-1_shTAF1-AE 213 bp overlap

SMAD2-3 1 dataset

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 393 bp overlap

SMAD2_3 2 datasets

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 330 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 456 bp overlap

SMAD4 1 dataset

ChIP HGrC1_EV GSE138496.SMAD4.HGrC1_EV 164 bp overlap

SMARCA4 10 datasets

ChIP A-549_AG15677 GSE132290.SMARCA4.A-549_AG15677 61 bp overlap

ChIP A-549_AG15678 GSE132290.SMARCA4.A-549_AG15678 75 bp overlap

ChIP A-549_AG15686 GSE132290.SMARCA4.A-549_AG15686 292 bp overlap

ChIP A-549_AG15720 GSE132290.SMARCA4.A-549_AG15720 94 bp overlap

ChIP A-549_AG15722 GSE132290.SMARCA4.A-549_AG15722 70 bp overlap

ChIP A-549_AG15725 GSE132290.SMARCA4.A-549_AG15725 127 bp overlap

ChIP BIN-67_lentivirus-SMARCA4 GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4 349 bp overlap

ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-K785R 398 bp overlap

ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-T910M 225 bp overlap

ChIP endometrial-epithelial-cells_KO GSE106660.SMARCA4.endometrial-epithelial-cells_KO 296 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 435 bp overlap

STAT1 2 datasets

ChIP CD14_INFG_LPS GSE43036.STAT1.CD14_INFG_LPS 247 bp overlap

ChIP CD14_LPS GSE43036.STAT1.CD14_LPS 157 bp overlap

STAT1_pS727 1 dataset

ChIP SET-2 GSE100566.STAT1_pS727.SET-2 377 bp overlap

STAT3 4 datasets

ChIP MDA-MB-157_EtOH GSE85579.STAT3.MDA-MB-157_EtOH 337 bp overlap

ChIP MDA-MB-231 GSE152203.STAT3.MDA-MB-231 312 bp overlap

ChIP MDA-MB-231_EtOH GSE85579.STAT3.MDA-MB-231_EtOH 404 bp overlap

ChIP SUM159PT GSE152203.STAT3.SUM159PT 213 bp overlap

TAL1 3 datasets

ChIP CHRF28811 ERP008568.TAL1.CHRF28811 293 bp overlap

ChIP ProEs GSE59087.TAL1.ProEs 117 bp overlap

ChIP TSU-1621MT GSE60477.TAL1.TSU-1621MT 270 bp overlap

TARDBP 1 dataset

ChIP GM12878 ENCSR412QBS.TARDBP.GM12878 514 bp overlap

TCF21 1 dataset

ChIP HCASMC GSE124011.TCF21.HCASMC 307 bp overlap

ChIP Kasumi-1 GSE43834.TCF3.Kasumi-1 206 bp overlap

ChIP keratinocyte_diff GSE33571.TP63.keratinocyte_diff 65 bp overlap

ChIP K-562 ENCSR000EFZ.UBTF.K-562 103 bp overlap

USF1 3 datasets

ChIP Ishikawa ENCFF728IEG 261 bp overlap

ChIP Ishikawa ENCSR000BSX.USF1.Ishikawa 137 bp overlap

ChIP SK-N-SH ENCSR000BMF.USF1.SK-N-SH 165 bp overlap

USF2 2 datasets

ChIP GM12878 GSE97661.USF2.GM12878 205 bp overlap

ChIP IMR-90 ENCSR513UQG.USF2.IMR-90 162 bp overlap

ChIP Huh-7 GSE97411.YY1.Huh-7 255 bp overlap

ChIP K562 ENCFF169LZT 288 bp overlap

ChIP HEK293 ENCFF033NQQ 320 bp overlap

ZNF263 1 dataset

ChIP K-562 ENCSR000EWN.ZNF263.K-562 118 bp overlap

ZNF572 1 dataset

ChIP Hep-G2 ENCSR663CTC.ZNF572.Hep-G2 172 bp overlap

ZNF687 2 datasets

ChIP GM12878 ENCFF233SGE 419 bp overlap

ChIP GM12878 ENCSR859FDL.ZNF687.GM12878 289 bp overlap

ZNF770 1 dataset

ChIP HEK293 GSE76494.ZNF770.HEK293 83 bp overlap