chr1:53,430,779–53,431,233

chr1 : 53,430,779 – 53,431,233

454 bp 103 TFs 8 linked genes

This 454 bp open chromatin element is linked to 8 target genes and is bound by 103 transcription factors.

Linked Genes

8 genes

Gene	Expression	Dist. to TSS	Distance	Link type
SLC25A3P1		8.3 kb	Proximal	Proximity
ENSG00000293253		8.7 kb	Proximal	Proximity
LRP8-DT		102.7 kb	Distal	Multiome
LRP8		103.0 kb	Distal	Multiome
MAGOH-DT		192.4 kb	Distal	Multiome
MAGOH		192.4 kb	Distal	Multiome
CZIB		210.3 kb	Distal	Multiome
CPT2		234.1 kb	Distal	Multiome

Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding

103 transcription factors

ARID1A 1 dataset

ChIP HAP1 GSE108387.ARID1A.HAP1 299 bp overlap

ASH2L 2 datasets

ChIP H1 ENCFF399KAM 454 bp overlap

ChIP WA01 ENCSR850KIP.ASH2L.WA01 363 bp overlap

ATF2 2 datasets

ChIP H1 ENCFF295GZO 454 bp overlap

ChIP WA01 ENCSR000BQU.ATF2.WA01 161 bp overlap

BCL11A 3 datasets

ChIP H1 ENCFF836SSR 177 bp overlap

ChIP WA01 ENCSR000BMJ.BCL11A.WA01 118 bp overlap

ChIP WA01 ENCSR000BIP.BCL11A.WA01 112 bp overlap

ChIP WA01 GSE104690.BCOR.WA01 163 bp overlap

ChIP SW480 GSE110473.BRD4.SW480 256 bp overlap

ChIP WTC11 ENCFF113HIY 437 bp overlap

ChIP H1 ENCFF991MKH 331 bp overlap

CHD7 2 datasets

ChIP H1 ENCFF126NLU 299 bp overlap

ChIP WA01 ENCSR000AVA.CHD7.WA01 313 bp overlap

CREB1 4 datasets

ChIP GM23338 ENCFF432ZEW 305 bp overlap

ChIP GM23338 ENCSR214ZAV.CREB1.GM23338 274 bp overlap

ChIP H1 ENCFF955PMP 321 bp overlap

ChIP WA01 ENCSR000BSN.CREB1.WA01 131 bp overlap

CTCF 4 datasets

ChIP C4-2B ENCFF821XVN 139 bp overlap

ChIP C4-2B ENCFF821XVN 346 bp overlap

ChIP VCaP ENCFF858YQT 57 bp overlap

ChIP VCaP ENCFF858YQT 265 bp overlap

CTNNB1 2 datasets

ChIP hESC_YAP-_activinA_15h GSE99202.CTNNB1.hESC_YAP-_activinA_15h 272 bp overlap

ChIP hESC_activinA_15h GSE99202.CTNNB1.hESC_activinA_15h 285 bp overlap

ChIP NTERA2 GSE58641.DDX5.NTERA2 336 bp overlap

EOMES 1 dataset

ChIP hESC GSE26097.EOMES.hESC 247 bp overlap

EP300 1 dataset

ChIP WA01 ENCSR000BKK.EP300.WA01 302 bp overlap

ChIP WTC11 ENCFF812SCD 407 bp overlap

FOSL1 1 dataset

ChIP H1 ENCFF920RFC 217 bp overlap

FOXH1 3 datasets

Motif DE_12h DE_12h-FOXH1_MA0479.2 8 bp overlap

Motif DE_24h DE_24h-FOXH1_MA0479.2 8 bp overlap

Motif ES_0h ES_0h-FOXH1_MA0479.2 8 bp overlap

FOXK1 1 dataset

ChIP WTC11 ENCFF875IGU 391 bp overlap

FOXP1 1 dataset

ChIP H9 GSE31006.FOXP1.H9 251 bp overlap

FOXP4 1 dataset

ChIP WTC11 ENCFF708TAF 377 bp overlap

GATA6 4 datasets

ChIP DE_D1 S09-DE-d1-GATA6-exp1 320 bp overlap

ChIP DE_D1 S14-DE-d1-GATA6-exp1 382 bp overlap

ChIP DE_D2 S55-DE-d2-GATA6-exp2 277 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 320 bp overlap

HAND2 1 dataset

Motif DE_24h DE_24h-HAND2_MA1638.2 6 bp overlap

HDAC2 3 datasets

ChIP H1 ENCFF353UJQ 454 bp overlap

ChIP H1 ENCFF939VKA 237 bp overlap

ChIP WA01 ENCSR000BNR.HDAC2.WA01 237 bp overlap

Hand1 1 dataset

Motif ES_0h ES_0h-Hand1_MA2123.1 9 bp overlap

ChIP DE_D1 S08-DE-d1-JUN-exp1 454 bp overlap

ChIP DE_D1 S40-DE-d1-JUN-exp2 383 bp overlap

ChIP DE_D2 S02-DE-d2-JUN-exp1 430 bp overlap

ChIP DE_D2 S54-DE-d2-JUN-exp2 135 bp overlap

ChIP ESC S24-ESC-d0-JUN-exp1 424 bp overlap

ChIP ESC S34-ESC-d0-JUN-exp2 406 bp overlap

ChIP HUES-8 GSE109524.JUN.HUES-8 389 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.JUN.HUES-8_DE_ctrl 454 bp overlap

ChIP H1 ENCFF914VQY 357 bp overlap

ChIP hESC_PRIMED GSE69646.MED1.hESC_PRIMED 454 bp overlap

MEIS1 2 datasets

Motif DE_24h DE_24h-MEIS1_MA0498.3 5 bp overlap

Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap

ChIP H1 ENCFF963FZS 337 bp overlap

NANOG 10 datasets

ChIP GM23338 ENCFF065NZG 311 bp overlap

ChIP GM23338 ENCSR061DGF.NANOG.GM23338 113 bp overlap

ChIP H1 ENCFF747ZPQ 241 bp overlap

ChIP HUES-8 GSE109524.NANOG.HUES-8 454 bp overlap

ChIP WA01 ENCSR000BMT.NANOG.WA01 230 bp overlap

ChIP WA01 ERP004238.NANOG.WA01 426 bp overlap

ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 454 bp overlap

ChIP WA09 GSE105028.NANOG.WA09 439 bp overlap

ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 454 bp overlap

ChIP hESC GSE20650.NANOG.hESC 157 bp overlap

NEUROD1 1 dataset

Motif DE_24h DE_24h-NEUROD1_MA1109.2 8 bp overlap

NEUROG2 1 dataset

Motif DE_24h DE_24h-NEUROG2_MA1642.2 7 bp overlap

NFE2L1 1 dataset

ChIP WTC11 ENCFF644BPU 362 bp overlap

NIPBL 3 datasets

ChIP hESC GSE64758.NIPBL.hESC 258 bp overlap

ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 210 bp overlap

ChIP hESC_WNT3A_ACTIVIN GSE64758.NIPBL.hESC_WNT3A_ACTIVIN 368 bp overlap

ChIP HepG2 ENCFF694NVY 94 bp overlap

Neurod2 1 dataset

Motif DE_24h DE_24h-Neurod2_MA0668.3 8 bp overlap

Nfatc2 2 datasets

Motif DE_24h DE_24h-Nfatc2_MA0152.3 8 bp overlap

Motif ES_0h ES_0h-Nfatc2_MA0152.3 8 bp overlap

ChIP WTC11 ENCFF634NAO 245 bp overlap

PKNOX2 2 datasets

Motif DE_24h DE_24h-PKNOX2_MA0783.1 12 bp overlap

Motif ES_0h ES_0h-PKNOX2_MA0783.1 12 bp overlap

POU1F1 3 datasets

Motif DE_12h DE_12h-POU1F1_MA0784.3 14 bp overlap

Motif DE_24h DE_24h-POU1F1_MA0784.3 14 bp overlap

Motif ES_0h ES_0h-POU1F1_MA0784.3 14 bp overlap

POU2F1 4 datasets

Motif DE_12h DE_12h-POU2F1_MA0785.2 9 bp overlap

Motif DE_24h DE_24h-POU2F1_MA0785.2 9 bp overlap

Motif DE_24h DE_24h-POU2F1_MA0785.2 9 bp overlap

Motif ES_0h ES_0h-POU2F1_MA0785.2 9 bp overlap

POU2F1::SOX2 3 datasets

Motif DE_12h DE_12h-POU2F1SOX2_MA1962.1 17 bp overlap

Motif DE_24h DE_24h-POU2F1SOX2_MA1962.1 17 bp overlap

Motif ES_0h ES_0h-POU2F1SOX2_MA1962.1 17 bp overlap

POU2F2 3 datasets

Motif DE_12h DE_12h-POU2F2_MA0507.3 13 bp overlap

Motif DE_24h DE_24h-POU2F2_MA0507.3 13 bp overlap

Motif ES_0h ES_0h-POU2F2_MA0507.3 13 bp overlap

POU2F3 2 datasets

Motif DE_24h DE_24h-POU2F3_MA0627.3 9 bp overlap

ChIP NCI-H1048 GSE115123.POU2F3.NCI-H1048 214 bp overlap

POU3F1 5 datasets

Motif DE_12h DE_12h-POU3F1_MA0786.2 10 bp overlap

Motif DE_24h DE_24h-POU3F1_MA0786.2 10 bp overlap

Motif DE_24h DE_24h-POU3F1_MA0786.2 10 bp overlap

Motif DE_24h DE_24h-POU3F1_MA0786.2 10 bp overlap

Motif ES_0h ES_0h-POU3F1_MA0786.2 10 bp overlap

POU3F2 4 datasets

Motif DE_12h DE_12h-POU3F2_MA0787.1 12 bp overlap

Motif DE_24h DE_24h-POU3F2_MA0787.1 12 bp overlap

Motif DE_24h DE_24h-POU3F2_MA0787.1 12 bp overlap

Motif ES_0h ES_0h-POU3F2_MA0787.1 12 bp overlap

POU3F3 3 datasets

Motif DE_12h DE_12h-POU3F3_MA0788.1 13 bp overlap

Motif DE_24h DE_24h-POU3F3_MA0788.1 13 bp overlap

Motif ES_0h ES_0h-POU3F3_MA0788.1 13 bp overlap

POU3F4 1 dataset

Motif DE_24h DE_24h-POU3F4_MA0789.1 9 bp overlap

POU5F1 14 datasets

Motif DE_24h DE_24h-POU5F1_MA1115.2 7 bp overlap

Motif DE_24h DE_24h-POU5F1_MA1115.2 7 bp overlap

ChIP DE_D1 DED1-OCT4_Batch_II 395 bp overlap

ChIP GM23338 ENCFF333SNB 311 bp overlap

ChIP H1 ENCFF698ZAP 205 bp overlap

ChIP HUES-8 GSE109524.POU5F1.HUES-8 454 bp overlap

ChIP NCCIT GSE36134.POU5F1.NCCIT 197 bp overlap

ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 454 bp overlap

ChIP WA09 GSE105028.POU5F1.WA09 208 bp overlap

ChIP WA09_heat-shock GSE105028.POU5F1.WA09_heat-shock 337 bp overlap

ChIP hESC ENCSR264RJX.POU5F1.hESC 178 bp overlap

ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 402 bp overlap

ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 454 bp overlap

ChIP hiPSC GSE56567.POU5F1.hiPSC 313 bp overlap

POU5F1B 4 datasets

Motif DE_12h DE_12h-POU5F1B_MA0792.1 9 bp overlap

Motif DE_24h DE_24h-POU5F1B_MA0792.1 9 bp overlap

Motif DE_24h DE_24h-POU5F1B_MA0792.1 9 bp overlap

Motif ES_0h ES_0h-POU5F1B_MA0792.1 9 bp overlap

POU5F1_M 1 dataset

ChIP DE_D1 DED1-OCT4-M_Batch_II 338 bp overlap

Pou5f1::Sox2 3 datasets

Motif DE_12h DE_12h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif DE_24h DE_24h-Pou5f1Sox2_MA0142.1 15 bp overlap

Motif ES_0h ES_0h-Pou5f1Sox2_MA0142.1 15 bp overlap

Prdm15 2 datasets

Motif DE_24h DE_24h-Prdm15_MA1616.2 11 bp overlap

Motif ES_0h ES_0h-Prdm15_MA1616.2 11 bp overlap

Ptf1A 1 dataset

Motif DE_24h DE_24h-Ptf1A_MA1618.2 9 bp overlap

RAD21 4 datasets

ChIP H1 ENCFF698EWO 241 bp overlap

ChIP HAP1 GSE126634.RAD21.HAP1 153 bp overlap

ChIP HAP1 GSE152721.RAD21.HAP1 180 bp overlap

ChIP HAP1_CTCF GSE126634.RAD21.HAP1_CTCF 203 bp overlap

ChIP MUTUL GSE75503.RBPJ.MUTUL 57 bp overlap

SCRT1 5 datasets

Motif DE_12h DE_12h-SCRT1_MA0743.3 10 bp overlap

Motif DE_24h DE_24h-SCRT1_MA0743.3 10 bp overlap

Motif ES_0h ES_0h-SCRT1_MA0743.3 10 bp overlap

ChIP HEK293 ENCFF513YVP 384 bp overlap

ChIP HEK293 ENCSR605MGM.SCRT1.HEK293 229 bp overlap

SCRT2 3 datasets

Motif DE_12h DE_12h-SCRT2_MA0744.3 10 bp overlap

Motif DE_24h DE_24h-SCRT2_MA0744.3 10 bp overlap

Motif ES_0h ES_0h-SCRT2_MA0744.3 10 bp overlap

SIN3A 5 datasets

ChIP H1 ENCFF042ZSL 354 bp overlap

ChIP H1 ENCFF896IJG 301 bp overlap

ChIP WA01 ENCSR000EBO.SIN3A.WA01 277 bp overlap

ChIP WA01 ENCSR000BIS.SIN3A.WA01 183 bp overlap

ChIP hiPSC_IB12 GSE106870.SIN3A.hiPSC_IB12 215 bp overlap

SMAD2 4 datasets

Motif DE_24h DE_24h-SMAD2_MA1964.2 6 bp overlap

Motif ES_0h ES_0h-SMAD2_MA1964.2 6 bp overlap

ChIP hESC_YAP-_activinA_15h GSE99202.SMAD2.hESC_YAP-_activinA_15h 454 bp overlap

ChIP hESC_activinA_15h GSE99202.SMAD2.hESC_activinA_15h 454 bp overlap

SMAD2-3 3 datasets

ChIP HUES-8 GSE109524.SMAD2-3.HUES-8 349 bp overlap

ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 454 bp overlap

ChIP HUES-8_DE_ctrl GSE109524.SMAD2-3.HUES-8_DE_ctrl 454 bp overlap

SMAD2_3 6 datasets

ChIP DE_D1 S07-DE-d1-SMAD2_3-exp1 454 bp overlap

ChIP DE_D1 S12-DE-d1-SMAD2_3-exp1 454 bp overlap

ChIP DE_D1 S39-DE-d1-SMAD2_3-exp2 454 bp overlap

ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 454 bp overlap

ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 454 bp overlap

ChIP ESC S33-ESC-d0-SMAD2_3-exp2 286 bp overlap

SMAD3 3 datasets

ChIP BG03 GSE21614.SMAD3.BG03 209 bp overlap

ChIP BG03_DIFF_2H GSE36578.SMAD3.BG03_DIFF_2H 319 bp overlap

ChIP BG03_DIFF_48H GSE36578.SMAD3.BG03_DIFF_48H 284 bp overlap

SMARCA4 4 datasets

ChIP NSC GSE125033.SMARCA4.NSC 191 bp overlap

ChIP WA09_heat-shock GSE105028.SMARCA4.WA09_heat-shock 238 bp overlap

ChIP hiPSC GSE124903.SMARCA4.hiPSC 454 bp overlap

ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 454 bp overlap

SMARCB1 2 datasets

ChIP hiPSC GSE124903.SMARCB1.hiPSC 353 bp overlap

ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 391 bp overlap

SMARCC1 3 datasets

ChIP ESC S25-ESC-d0-BAF155-exp1 454 bp overlap

ChIP hiPSC GSE124903.SMARCC1.hiPSC 422 bp overlap

ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 453 bp overlap

SOX10 2 datasets

Motif DE_24h DE_24h-SOX10_MA0442.3 6 bp overlap

Motif ES_0h ES_0h-SOX10_MA0442.3 6 bp overlap

SOX17 1 dataset

ChIP DE_D2 DED2-SOX17_Batch_II 250 bp overlap

SOX17_M 1 dataset

ChIP DE_D2 DED2-SOX17-M_Batch_II 381 bp overlap

ChIP hiPSC GSE56567.SOX2.hiPSC 454 bp overlap

SOX4 2 datasets

Motif DE_24h DE_24h-SOX4_MA0867.3 8 bp overlap

Motif ES_0h ES_0h-SOX4_MA0867.3 8 bp overlap

ChIP RH4_Entinostat-6H GSE116344.SOX8.RH4_Entinostat-6H 243 bp overlap

ChIP H1 ENCFF263FUH 321 bp overlap

ChIP WA01 ENCSR000BIR.SP1.WA01 385 bp overlap

ChIP WTC11 ENCFF688PEU 422 bp overlap

ChIP WA01 ENCSR000BQV.SP4.WA01 139 bp overlap

Sox6 2 datasets

Motif DE_24h DE_24h-Sox6_MA0515.1 10 bp overlap

Motif ES_0h ES_0h-Sox6_MA0515.1 10 bp overlap

ChIP H9_ENDODERM GSE60606.T.H9_ENDODERM 253 bp overlap

ChIP H1 ENCFF859IIO 377 bp overlap

ChIP H1 ENCFF859IIO 175 bp overlap

TBX1 2 datasets

Motif DE_24h DE_24h-TBX1_MA0805.1 8 bp overlap

Motif ES_0h ES_0h-TBX1_MA0805.1 8 bp overlap

TBX15 2 datasets

Motif DE_24h DE_24h-TBX15_MA0803.1 8 bp overlap

Motif ES_0h ES_0h-TBX15_MA0803.1 8 bp overlap

TBX18 2 datasets

Motif DE_24h DE_24h-TBX18_MA1565.2 9 bp overlap

Motif ES_0h ES_0h-TBX18_MA1565.2 9 bp overlap

TBX2 2 datasets

Motif DE_24h DE_24h-TBX2_MA0688.2 9 bp overlap

Motif ES_0h ES_0h-TBX2_MA0688.2 9 bp overlap

TBX21 2 datasets

Motif DE_24h DE_24h-TBX21_MA0690.3 10 bp overlap

Motif ES_0h ES_0h-TBX21_MA0690.3 10 bp overlap

TBX3 2 datasets

Motif DE_24h DE_24h-TBX3_MA1566.3 9 bp overlap

Motif ES_0h ES_0h-TBX3_MA1566.3 9 bp overlap

TBX4 2 datasets

Motif DE_24h DE_24h-TBX4_MA0806.1 8 bp overlap

Motif ES_0h ES_0h-TBX4_MA0806.1 8 bp overlap

TBX5 2 datasets

Motif DE_24h DE_24h-TBX5_MA0807.1 8 bp overlap

Motif ES_0h ES_0h-TBX5_MA0807.1 8 bp overlap

TCF12 2 datasets

ChIP H1 ENCFF203EBH 251 bp overlap

ChIP WA01 ENCSR000BIT.TCF12.WA01 184 bp overlap

ChIP NPC GSE154479.TCF3.NPC 395 bp overlap

TEAD1 1 dataset

ChIP WTC11 ENCFF502QUV 405 bp overlap

TEAD4 9 datasets

ChIP BJ_fibroblast GSE114367.TEAD4.BJ_fibroblast 223 bp overlap

ChIP BJ_fibroblast_CD13-neg GSE114367.TEAD4.BJ_fibroblast_CD13-neg 256 bp overlap

ChIP BJ_fibroblast_CD13-pos GSE114367.TEAD4.BJ_fibroblast_CD13-pos 270 bp overlap

Motif DE_12h DE_12h-TEAD4_MA0809.3 8 bp overlap

Motif DE_24h DE_24h-TEAD4_MA0809.3 8 bp overlap

ChIP ESC S26-ESC-d0-TEAD4-exp1 454 bp overlap

Motif ES_0h ES_0h-TEAD4_MA0809.3 8 bp overlap

ChIP H1 ENCFF778PAX 245 bp overlap

ChIP hESC GSE99202.TEAD4.hESC 208 bp overlap

TGIF1 2 datasets

Motif DE_24h DE_24h-TGIF1_MA0796.1 12 bp overlap

Motif ES_0h ES_0h-TGIF1_MA0796.1 12 bp overlap

TGIF2 2 datasets

Motif DE_24h DE_24h-TGIF2_MA0797.1 12 bp overlap

Motif ES_0h ES_0h-TGIF2_MA0797.1 12 bp overlap

TP53 4 datasets

ChIP H9 GSE142050.TP53.H9 344 bp overlap

ChIP H9_ectoderm GSE142050.TP53.H9_ectoderm 447 bp overlap

ChIP H9_mesoderm GSE142050.TP53.H9_mesoderm 281 bp overlap

ChIP WTC11 ENCFF359JCU 412 bp overlap

TRIM28 1 dataset

ChIP WIBR3_NAIVE GSE84382.TRIM28.WIBR3_NAIVE 178 bp overlap

TWIST1 1 dataset

Motif DE_24h DE_24h-TWIST1_MA1123.3 8 bp overlap

ChIP H1 ENCFF524BTL 337 bp overlap

ChIP WA01 ENCSR000BKD.YY1.WA01 275 bp overlap

ZBTB7C 2 datasets

Motif DE_24h DE_24h-ZBTB7C_MA0695.2 8 bp overlap

Motif ES_0h ES_0h-ZBTB7C_MA0695.2 8 bp overlap

ZNF184 1 dataset

ChIP WTC11 ENCFF352POG 454 bp overlap

ZNF207 1 dataset

ChIP WA09 GSE118632.ZNF207.WA09 407 bp overlap

ZNF462 2 datasets

ChIP GM23338 ENCFF896CCA 251 bp overlap

ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 222 bp overlap

ZNF677 1 dataset

Motif ES_0h ES_0h-ZNF677_MA2101.1 12 bp overlap

ZNF766 1 dataset

Motif ES_0h ES_0h-ZNF766_MA2098.1 9 bp overlap

ZSCAN4 2 datasets

ChIP HEK293 ENCFF381BKT 203 bp overlap

ChIP HEK293 ENCSR211GNP.ZSCAN4.HEK293 365 bp overlap