chr2 : 174,795,866 – 174,796,779
913 bp 95 TFs 1 linked gene
This 913 bp open chromatin element is linked to CHRNA1 and is bound by 95 transcription factors.
Linked Genes
1 gene
Gene↕ Expression Dist. to TSS↑ Distance↕ Link type↕
CHRNA1 7.9 kb Proximal Proximity
Chromatin Accessibility

Genome Browser

Genomic view centred on this element. Tracks include ATAC-seq accessibility, RNA-seq expression, TF binding peaks, and element-to-gene loop arcs across the ESC → DE time course.

View limited to ±500 kb around this element.
For the full data, please see the UCSC track linked below.
chr2:174,790,866 – 174,801,779
This element Other elements Gene links ATAC-seq RNA-seq

Transcription factors with ChIP-seq peak overlap or TOBIAS motif footprint evidence at this element.

TF Binding
95 transcription factors
Source
Cell type
ARID2 2 datasets
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.ARID2.BIN-67_lentivirus-SMARCA4 282 bp overlap
ChIP BIN-67_lentivirus-SMARCA4 GSE117734.ARID2.BIN-67_lentivirus-SMARCA4 57 bp overlap
ASH2L 1 dataset
ChIP WA01 ENCSR850KIP.ASH2L.WA01 292 bp overlap
ATF2 6 datasets
ChIP H1 ENCFF295GZO 524 bp overlap
ChIP HEK293 ENCFF194VKZ 124 bp overlap
ChIP HEK293 ENCSR217HTK.ATF2.HEK293 105 bp overlap
ChIP Hep-G2 ENCSR047BUZ.ATF2.Hep-G2 122 bp overlap
ChIP K-562 ENCSR869IUD.ATF2.K-562 73 bp overlap
ChIP WA01 ENCSR000BQU.ATF2.WA01 590 bp overlap
ATF6 2 datasets
Motif DE_60h DE_60h-ATF6_MA1466.2 13 bp overlap
Motif DE_72h DE_72h-ATF6_MA1466.2 13 bp overlap
BCL11A 7 datasets
ChIP CD34_Day3_30min GSE104676.BCL11A.CD34_Day3_30min 78 bp overlap
ChIP CD34_Day5_30min GSE104676.BCL11A.CD34_Day5_30min 163 bp overlap
ChIP CD34_Day7_15min GSE104676.BCL11A.CD34_Day7_15min 124 bp overlap
ChIP CD34_Day7_30min GSE104676.BCL11A.CD34_Day7_30min 164 bp overlap
ChIP CD34_Day7_60min GSE104676.BCL11A.CD34_Day7_60min 170 bp overlap
ChIP CD34_Day7_90min GSE104676.BCL11A.CD34_Day7_90min 118 bp overlap
ChIP CD34_Day9_30min GSE104676.BCL11A.CD34_Day9_30min 62 bp overlap
BRD4 6 datasets
ChIP CHL-1 GSE95585.BRD4.CHL-1 161 bp overlap
ChIP HFOB_DIFF GSE82295.BRD4.HFOB_DIFF 107 bp overlap
ChIP KK-1_DMSO GSE94732.BRD4.KK-1_DMSO 230 bp overlap
ChIP SW480 GSE110473.BRD4.SW480 568 bp overlap
ChIP SW480 GSE73319.BRD4.SW480 221 bp overlap
ChIP SW480_16h_TNF-a GSE110473.BRD4.SW480_16h_TNF-a 830 bp overlap
CDK8 1 dataset
ChIP SW480 GSE53602.CDK8.SW480 371 bp overlap
CHD7 2 datasets
ChIP WA01 ENCSR000AVA.CHD7.WA01 149 bp overlap
ChIP hiPSC_derived_lt-NES GSE108506.CHD7.hiPSC_derived_lt-NES 305 bp overlap
Cebpa 1 dataset
ChIP BLaER1 ENCFF460KDD 251 bp overlap
DPF2 2 datasets
ChIP BIN-67 GSE117734.DPF2.BIN-67 209 bp overlap
ChIP BIN-67_ctrl GSE117734.DPF2.BIN-67_ctrl 878 bp overlap
E2F6 1 dataset
ChIP WA01 ENCSR000BSI.E2F6.WA01 113 bp overlap
ETS1 1 dataset
ChIP HUVEC-C_VEGF_4H GSE41166.ETS1.HUVEC-C_VEGF_4H 192 bp overlap
EZH2 1 dataset
ChIP neural progenitor cell ENCFF018MKA 780 bp overlap
FEZF2 2 datasets
Motif DE_60h DE_60h-FEZF2_MA2341.1 8 bp overlap
Motif DE_72h DE_72h-FEZF2_MA2341.1 8 bp overlap
FOXA2 2 datasets
ChIP DE DE-FOXA2-1 734 bp overlap
ChIP DE DE-FOXA2-2 567 bp overlap
FOXB1 1 dataset
Motif ES_0h ES_0h-FOXB1_MA0845.1 11 bp overlap
FOXP1 1 dataset
ChIP H9 GSE31006.FOXP1.H9 156 bp overlap
GATA1 1 dataset
ChIP CD34_ERYTH_BIO GSE29194.GATA1.CD34_ERYTH_BIO 155 bp overlap
GATA1::TAL1 1 dataset
Motif DE_72h DE_72h-GATA1TAL1_MA0140.3 17 bp overlap
GATA2 1 dataset
ChIP TF1 GSE73207.GATA2.TF1 362 bp overlap
GATA3 1 dataset
ChIP SK-N-SH ENCFF040SSB 295 bp overlap
GATA4 5 datasets
ChIP DE DE-GATA4-1 613 bp overlap
ChIP DE DE-GATA4-2 716 bp overlap
ChIP foregut GSE117136.GATA4.foregut 598 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA4.pancreatic-progenitor 792 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA4.pancreatic-progenitor_PP1 504 bp overlap
GATA6 14 datasets
ChIP AGS GSE51705.GATA6.AGS 178 bp overlap
ChIP DE DE-GATA6-1 579 bp overlap
ChIP DE DE-GATA6-2 747 bp overlap
ChIP DE_D1 S09-DE-d1-GATA6-exp1 361 bp overlap
ChIP DE_D1 S14-DE-d1-GATA6-exp1 464 bp overlap
ChIP DE_D2 S55-DE-d2-GATA6-exp2 431 bp overlap
ChIP HUES-8_DE_JNKi GSE109524.GATA6.HUES-8_DE_JNKi 510 bp overlap
ChIP HUES-8_DE_ctrl GSE109524.GATA6.HUES-8_DE_ctrl 394 bp overlap
ChIP endoderm_KO GSE117136.GATA6.endoderm_KO 527 bp overlap
ChIP foregut GSE117136.GATA6.foregut 558 bp overlap
ChIP foregut_KO GSE117136.GATA6.foregut_KO 483 bp overlap
ChIP pancreatic-progenitor GSE117136.GATA6.pancreatic-progenitor 661 bp overlap
ChIP pancreatic-progenitor_KO GSE117136.GATA6.pancreatic-progenitor_KO 490 bp overlap
ChIP pancreatic-progenitor_PP1 GSE104840.GATA6.pancreatic-progenitor_PP1 442 bp overlap
HDAC2 1 dataset
ChIP H1 ENCFF939VKA 237 bp overlap
HOXB4 2 datasets
Motif DE_60h DE_60h-HOXB4_MA1499.2 6 bp overlap
Motif DE_72h DE_72h-HOXB4_MA1499.2 6 bp overlap
HOXC4 2 datasets
Motif DE_60h DE_60h-HOXC4_MA1504.2 6 bp overlap
Motif DE_72h DE_72h-HOXC4_MA1504.2 6 bp overlap
HOXD3 2 datasets
Motif DE_60h DE_60h-HOXD3_MA0912.2 8 bp overlap
Motif DE_72h DE_72h-HOXD3_MA0912.2 8 bp overlap
HOXD4 2 datasets
Motif DE_60h DE_60h-HOXD4_MA1507.2 6 bp overlap
Motif DE_72h DE_72h-HOXD4_MA1507.2 6 bp overlap
Hnf1A 1 dataset
Motif DE_72h DE_72h-Hnf1A_MA1991.2 10 bp overlap
IRF4 1 dataset
ChIP T-cell GSE136853.IRF4.T-cell 251 bp overlap
JUN 2 datasets
ChIP DE_D2 S02-DE-d2-JUN-exp1 272 bp overlap
ChIP Karpas-299 GSE151413.JUN.Karpas-299 836 bp overlap
KMT2B-D 1 dataset
ChIP SW480 GSE115985.KMT2B-D.SW480 640 bp overlap
LDB1 1 dataset
ChIP HEP GSE52637.LDB1.HEP 113 bp overlap
Lef1 1 dataset
Motif DE_72h DE_72h-Lef1_MA0768.3 8 bp overlap
MAF 1 dataset
ChIP CD4_Th1 GSE72266.MAF.CD4_Th1 281 bp overlap
MEIS1 1 dataset
Motif ES_0h ES_0h-MEIS1_MA0498.3 5 bp overlap
MPHOSPH8 1 dataset
ChIP H9 GSE95374.MPHOSPH8.H9 167 bp overlap
NANOG 8 datasets
ChIP H1 ENCFF747ZPQ 241 bp overlap
ChIP HUES-8 GSE109524.NANOG.HUES-8 506 bp overlap
ChIP WA01 ERP004238.NANOG.WA01 435 bp overlap
ChIP WA01 ENCSR000BMT.NANOG.WA01 255 bp overlap
ChIP WA01_3IL ERP004238.NANOG.WA01_3IL 579 bp overlap
ChIP WA09 GSE105028.NANOG.WA09 595 bp overlap
ChIP WA09_heat-shock GSE105028.NANOG.WA09_heat-shock 382 bp overlap
ChIP hESC GSE18292.NANOG.hESC 98 bp overlap
NFKB1 1 dataset
ChIP L1236 GSE63736.NFKB1.L1236 116 bp overlap
NFKB2 1 dataset
ChIP L1236 GSE63736.NFKB2.L1236 141 bp overlap
NIPBL 1 dataset
ChIP hESC_WNT3A GSE64758.NIPBL.hESC_WNT3A 183 bp overlap
NR3C1 1 dataset
ChIP BEAS-2B_TNF_IA1 GSE125623.NR3C1.BEAS-2B_TNF_IA1 372 bp overlap
NR4A1 1 dataset
Motif DE_72h DE_72h-NR4A1_MA1112.3 8 bp overlap
PDX1 1 dataset
ChIP pancreatic-progenitor GSE117136.PDX1.pancreatic-progenitor 480 bp overlap
POLR2A 2 datasets
ChIP H1 ENCFF566JSR 631 bp overlap
ChIP H1 ENCFF566JSR 620 bp overlap
POU1F1 2 datasets
Motif DE_60h DE_60h-POU1F1_MA0784.3 14 bp overlap
Motif DE_72h DE_72h-POU1F1_MA0784.3 14 bp overlap
POU2F1 2 datasets
Motif DE_60h DE_60h-POU2F1_MA0785.2 9 bp overlap
Motif DE_72h DE_72h-POU2F1_MA0785.2 9 bp overlap
POU2F2 2 datasets
Motif DE_60h DE_60h-POU2F2_MA0507.3 13 bp overlap
Motif DE_72h DE_72h-POU2F2_MA0507.3 13 bp overlap
POU2F3 2 datasets
Motif DE_60h DE_60h-POU2F3_MA0627.3 9 bp overlap
Motif DE_72h DE_72h-POU2F3_MA0627.3 9 bp overlap
POU3F1 2 datasets
Motif DE_60h DE_60h-POU3F1_MA0786.2 10 bp overlap
Motif DE_72h DE_72h-POU3F1_MA0786.2 10 bp overlap
POU3F2 2 datasets
Motif DE_60h DE_60h-POU3F2_MA0787.1 12 bp overlap
Motif DE_72h DE_72h-POU3F2_MA0787.1 12 bp overlap
POU3F3 2 datasets
Motif DE_60h DE_60h-POU3F3_MA0788.1 13 bp overlap
Motif DE_72h DE_72h-POU3F3_MA0788.1 13 bp overlap
POU3F4 2 datasets
Motif DE_60h DE_60h-POU3F4_MA0789.1 9 bp overlap
Motif DE_72h DE_72h-POU3F4_MA0789.1 9 bp overlap
POU5F1 6 datasets
ChIP HUES-8 GSE109524.POU5F1.HUES-8 547 bp overlap
ChIP NCCIT_SNF5 GSE36134.POU5F1.NCCIT_SNF5 432 bp overlap
ChIP hESC ENCSR264RJX.POU5F1.hESC 113 bp overlap
ChIP hESC_NAIVE GSE69646.POU5F1.hESC_NAIVE 359 bp overlap
ChIP hESC_PRIMED GSE69646.POU5F1.hESC_PRIMED 508 bp overlap
ChIP hiPSC GSE56567.POU5F1.hiPSC 260 bp overlap
POU5F1B 2 datasets
Motif DE_60h DE_60h-POU5F1B_MA0792.1 9 bp overlap
Motif DE_72h DE_72h-POU5F1B_MA0792.1 9 bp overlap
POU6F1 2 datasets
Motif DE_60h DE_60h-POU6F1_MA1549.2 7 bp overlap
Motif DE_72h DE_72h-POU6F1_MA1549.2 7 bp overlap
POU6F2 2 datasets
Motif DE_60h DE_60h-POU6F2_MA0793.2 9 bp overlap
Motif DE_72h DE_72h-POU6F2_MA0793.2 9 bp overlap
PRDM1 1 dataset
Motif DE_72h DE_72h-PRDM1_MA0508.4 7 bp overlap
PROX1 1 dataset
ChIP SW480 GSE60390.PROX1.SW480 130 bp overlap
RAD21 1 dataset
ChIP HAP1 GSE152721.RAD21.HAP1 254 bp overlap
REL 1 dataset
Motif DE_72h DE_72h-REL_MA0101.1 10 bp overlap
RELA 8 datasets
ChIP FaDu_LPS GSE132018.RELA.FaDu_LPS 218 bp overlap
ChIP HUVEC-C_TNF_JQ1 GSE53998.RELA.HUVEC-C_TNF_JQ1 218 bp overlap
ChIP IMR-90_TNF GSE43070.RELA.IMR-90_TNF 173 bp overlap
ChIP SGBS_TNF GSE64233.RELA.SGBS_TNF 175 bp overlap
ChIP SW480_16h_TNFa GSE102796.RELA.SW480_16h_TNFa 592 bp overlap
ChIP aortic-endothelial-cell_IL1B_D16 GSE139377.RELA.aortic-endothelial-cell_IL1B_D16 177 bp overlap
ChIP aortic-endothelial-cell_IL1B_D27 GSE139377.RELA.aortic-endothelial-cell_IL1B_D27 266 bp overlap
ChIP aortic-endothelial-cell_IL1B_D38 GSE139377.RELA.aortic-endothelial-cell_IL1B_D38 170 bp overlap
REST 1 dataset
Motif ES_0h ES_0h-REST_MA0138.3 20 bp overlap
SIN3A 2 datasets
ChIP WA01 ENCSR000EBO.SIN3A.WA01 248 bp overlap
ChIP hiPSC_IID12 GSE106870.SIN3A.hiPSC_IID12 174 bp overlap
SMAD2 2 datasets
Motif DE_60h DE_60h-SMAD2_MA1964.2 6 bp overlap
Motif DE_72h DE_72h-SMAD2_MA1964.2 6 bp overlap
SMAD2-3 1 dataset
ChIP HUES-8_DE GSE109524.SMAD2-3.HUES-8_DE 555 bp overlap
SMAD2_3 2 datasets
ChIP DE_D2 S01-DE-d2-SMAD2_3-exp1 527 bp overlap
ChIP DE_D2 S53-DE-d2-SMAD2_3-exp2 250 bp overlap
SMARCA4 5 datasets
ChIP 501-mel_SHSOX10 GSE61965.SMARCA4.501-mel_SHSOX10 534 bp overlap
ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCA4.BIN-67_lentivirus-SMARCA4-T910M 488 bp overlap
ChIP NSC GSE125033.SMARCA4.NSC 164 bp overlap
ChIP hiPSC GSE124903.SMARCA4.hiPSC 277 bp overlap
ChIP hiPSC_WT GSE124903.SMARCA4.hiPSC_WT 388 bp overlap
SMARCB1 2 datasets
ChIP hiPSC GSE124903.SMARCB1.hiPSC 221 bp overlap
ChIP hiPSC_WT GSE124903.SMARCB1.hiPSC_WT 392 bp overlap
SMARCC1 3 datasets
ChIP BIN-67_lentivirus-SMARCA4-K785R GSE117734.SMARCC1.BIN-67_lentivirus-SMARCA4-K785R 278 bp overlap
ChIP BIN-67_lentivirus-SMARCA4-T910M GSE117734.SMARCC1.BIN-67_lentivirus-SMARCA4-T910M 216 bp overlap
ChIP hiPSC_WT GSE124903.SMARCC1.hiPSC_WT 543 bp overlap
SOX10 1 dataset
Motif DE_72h DE_72h-SOX10_MA0442.3 6 bp overlap
SOX17 1 dataset
ChIP DE_D2 DED2-SOX17_Batch_II 261 bp overlap
SOX17_M 1 dataset
ChIP DE_D2 DED2-SOX17-M_Batch_II 326 bp overlap
SOX2 2 datasets
ChIP hESC GSE18292.SOX2.hESC 103 bp overlap
ChIP hiPSC GSE56567.SOX2.hiPSC 286 bp overlap
SOX21 1 dataset
ChIP neuroepithelilal-cells GSE110505.SOX21.neuroepithelilal-cells 457 bp overlap
SP1 1 dataset
ChIP WA01 ENCSR000BIR.SP1.WA01 180 bp overlap
Six4 1 dataset
Motif ES_0h ES_0h-Six4_MA2001.2 7 bp overlap
TAL1 1 dataset
ChIP K-562 GSE107726.TAL1.K-562 165 bp overlap
TCF12 1 dataset
ChIP SK-N-SH ENCFF147AHB 287 bp overlap
TCF7 1 dataset
Motif DE_72h DE_72h-TCF7_MA0769.3 7 bp overlap
TCF7L1 1 dataset
Motif DE_72h DE_72h-TCF7L1_MA1421.1 12 bp overlap
TEAD4 2 datasets
ChIP BJ_fibroblast_CD13-pos GSE114367.TEAD4.BJ_fibroblast_CD13-pos 281 bp overlap
ChIP H1 ENCFF778PAX 245 bp overlap
TFAP4 1 dataset
ChIP DLD-1 GSE46935.TFAP4.DLD-1 146 bp overlap
THRB 1 dataset
Motif DE_72h DE_72h-THRB_MA1575.2 17 bp overlap
TP53 2 datasets
ChIP SW480_0h_TNFa GSE102796.TP53.SW480_0h_TNFa 534 bp overlap
ChIP SW480_shp53_16h_TNF-a GSE115985.TP53.SW480_shp53_16h_TNF-a 487 bp overlap
Tfcp2l1 2 datasets
Motif DE_60h DE_60h-Tfcp2l1_MA0145.2 14 bp overlap
Motif DE_72h DE_72h-Tfcp2l1_MA0145.2 14 bp overlap
YY1 2 datasets
ChIP H1 ENCFF524BTL 337 bp overlap
ChIP WA01 ENCSR000BKD.YY1.WA01 256 bp overlap
ZBTB7A 1 dataset
ChIP HUDEP-2 GSE103445.ZBTB7A.HUDEP-2 264 bp overlap
ZNF211 1 dataset
Motif ES_0h ES_0h-ZNF211_MA1974.2 10 bp overlap
ZNF354A 1 dataset
Motif ES_0h ES_0h-ZNF354A_MA1978.2 20 bp overlap
ZNF416 1 dataset
Motif DE_72h DE_72h-ZNF416_MA1979.2 10 bp overlap
ZNF462 2 datasets
ChIP GM23338 ENCFF896CCA 251 bp overlap
ChIP GM23338 ENCSR334UWP.ZNF462.GM23338 275 bp overlap
ZNF682 1 dataset
Motif DE_72h DE_72h-ZNF682_MA1599.2 11 bp overlap
ZNF8 1 dataset
Motif ES_0h ES_0h-ZNF8_MA1718.1 20 bp overlap
ZNF823 1 dataset
ChIP HEK293T GSE78099.ZNF823.HEK293T 59 bp overlap
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